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      • KCI등재

        Measurement of the ^(236)U(n, f) Cross Section at n_TOF

        R. Sarmento,I. F. Goncalves,P. Vaz,M. Calviani,N. Colonna 한국물리학회 2011 THE JOURNAL OF THE KOREAN PHYSICAL SOCIETY Vol.59 No.23

        A precise knowledge of the ^(236)U neutron-induced fission cross-section is required for the development of accelerator-driven systems and reactors based on the Th-U cycle. The evaluated data presently stored in the nuclear data libraries rely on outdated experimental measurements and show large discrepancies in the energy region between 1 keV and 100 keV. More recent measurements made at LANSCE and GELINA yielded results which are in disagreement with the literature for the resonance region and below 10 eV. In order to improve the present knowledge of the ^(236)U(n, f) cross-section, a new measurement was performed at the neutron Time-Of-Flight facility n_TOF at CERN. A Fast Ionization Chamber was used, in which four samples of ^(236)U and two of ^(235)U were mounted. The ^(236)U(n,f) cross-section was determined relative to the standard ^(235)U(n, f) reaction. The contribution from the ^(235)U contamination in the samples was subtracted, together with the alpha-particle background. Finally, the data were corrected for dead-time and detection efficiency. The n_TOF results on the ^(236)U(n, f) cross-section are reported in the neutron energy region from 200 meV to 2 MeV. The present high-resolution data point to several shortcomings in the current evaluated databases in the sub-threshold region. High accuracy cross-sections, important for applications to fast nuclear reactors as well as for fundamental Nuclear Physics, are also reported here.

      • KCI등재

        Assessment performance of Eucalyptus clones attacked by the recent invasion of Leptocybe invasa (Hymenoptera: Eulophidae): Implications to invasion pest management

        Carvalho M.A.F.,Pinto I.O.,Sarmento M.I.,Carvalho P.H.N.,da Silva R.S.,Rocha J.P.L.,Sarmento R.A. 한국응용곤충학회 2022 Journal of Asia-Pacific Entomology Vol.25 No.3

        Eucalyptus gall wasp, Leptocybe invasa is one of the most important invasive pests of Eucalyptus (Myrtaceae) and has been reported in new cultivation areas worldwide. This pest causes severe damage to susceptible plants of the genus Eucalyptus, where it induces galls in the midribs and petioles of young leaves and the internodes of branch and apices. In this work, we evaluated the response of Eucalyptus clones (E. urophylla (Urophylla) and two clone hybrids, one of the E. urophylla × E. camaldulensis (Urocam) and other of E. urophylla × E. grandis (Urograndis) crossings.) submitted to L. invasa collected from areas where L. invasa was recently reported. Our results show that the eucalypt materials cultivated in the areas where L. invasa were reported sensitive to L. invasa attacks. However, the wasp causes fewer galls in the Urocam clone. Thus, the Urocam clone can be preferred for use to reduce population growth of L. invasa in Brazilian savannah areas.

      • SCOPUSKCI등재

        Original Article : Influence of P53 on the radiotherapy response of hepatocellular carcinoma

        ( Ana R. Gomes ),( Ana M. Abrantes ),( Ana F. Brito ),( Mafalda Laranjo ),( Joao E. Casalta Lopes ),( Ana C. Goncalves ),( Ana B. Sarmento Ribeiro ),( Maria F. Botelho ),( Jose G. Tralhao ) 대한간학회 2015 Clinical and Molecular Hepatology(대한간학회지) Vol.21 No.3

        Background/Aims: Hepatocellular carcinoma (HCC) is one of the most common cancers worldwide, and it has a poor prognosis and few therapeutic options. Radiotherapy is one of the most effective forms of cancer treatment, and P53 protein is one of the key molecules determining how a cell responds to radiotherapy. The aim of this study was to determine the therapeutic effi cacy of iodine-131 in three human HCC cell lines. Methods: Western blotting was used to measure P53 expression. The effects of radiotherapy with iodine-131 were assessed by using the clonogenic assay to evaluate cell survival. Flow cytometry was carried out to examine the effectsof iodine-131 on cell death, oxidative stress, reduced intracellular glutathione expression, the mitochondrial membrane potential, and the cell cycle. Results: The P53 protein was not expressed in Hep3B2.1-7 cells, was expressed at normal levels in HepG2 cells, and was overexpressed in HuH7 cells. P53 expression in the HuH7 and HepG2 cell lines increased after internal and external irradiation with iodine-131. Irradiation induced a decrease in cell survival and led to a decrease in cell viability in all of the cell lines studied, accompanied by cell death via late apoptosis/necrosis and necrosis. Irradiation with 131-iodine induced mostly cell-cycle arrest in the G0/G1 phase. Conclusions: These results suggest that P53 plays a key role in the radiotherapy response of HCC. (Clin Mol Hepatol 2015;21:257-267)

      • KCI등재

        A Transparent Detector for n_TOF Neutron Beam Monitoring

        S. Andriamonje,M. Calviani,Y. Kadi,R. Losito,V. Vlachoudis,E. Berthoumieux,F. Gunsing,A. Giganon,Y. Giomataris,C. Guerrero,R. Sarmento,P. Schillebeeckx,P. Siegler 한국물리학회 2011 THE JOURNAL OF THE KOREAN PHYSICAL SOCIETY Vol.59 No.23

        In order to obtain high precision cross-section measurements using the time-of-flight technique, it is important to know with good accuracy the neutron uence at the measuring station. The detector dedicated to these measurements should be placed upstream of the detectors used for capture and fission cross-section measurements. The main requirement is to reduce the material of the detector as much as possible, in order to minimize the perturbation of the neutron beam and, especially, the background produced by the device itself. According to these considerations, a new neutron detector equipped with a small-mass device based on MicroMegas "Micro-bulk" technology has been developed as a monitoring detector for the CERN n TOF neutron beam. A description of the different characteristics of this innovative concept of transparent detector for neutron beam monitoring is presented. The result obtained in the commissioning of the new spallation targetof the n TOF facility at CERN is shown, compared with simulations performed with the FLUKA code.

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