An Improved Lightweight Two-Factor Authentication and Key Agreement Protocol with Dynamic Identity Based on Elliptic Curve Cryptography

( Shuming Qiu ),( Guosheng Xu ),( Haseeb Ahmad ),( Guoai Xu ),( Xinping Qiu ),( Hong Xu ) 한국인터넷정보학회 2019 KSII Transactions on Internet and Information Syst Vol.13 No.2

With the rapid development of the Internet of Things, the problem of privacy protection has been paid great attention. Recently, Nikooghadam et al. pointed out that Kumari et al.’s protocol can neither resist off-line guessing attack nor preserve user anonymity. Moreover, the authors also proposed an authentication supportive session initial protocol, claiming to resist various vulnerability attacks. Unfortunately, this paper proves that the authentication protocols of Kumari et al. and Nikooghadam et al. have neither the ability to preserve perfect forward secrecy nor the ability to resist key-compromise impersonation attack. In order to remedy such flaws in their protocols, we design a lightweight authentication protocol using elliptic curve cryptography. By way of informal security analysis, it is shown that the proposed protocol can both resist a variety of attacks and provide more security. Afterward, it is also proved that the protocol is resistant against active and passive attacks under Dolev-Yao model by means of Burrows-Abadi-Needham logic (BAN-Logic), and fulfills mutual authentication using Automated Validation of Internet Security Protocols and Applications (AVISPA) software. Subsequently, we compare the protocol with the related scheme in terms of computational complexity and security. The comparative analytics witness that the proposed protocol is more suitable for practical application scenarios.

An Increase in Synaptic NMDA Receptors in the Insular Cortex Contributes to Neuropathic Pain

Qiu, Shuang,Chen, Tao,Koga, Kohei,Guo, Yan-yan,Xu, Hui,Song, Qian,Wang, Jie-jie,Descalzi, Giannina,Kaang, Bong-Kiun,Luo, Jian-hong,Zhuo, Min,Zhao, Ming-gao AAAS 2013 Science signaling Vol.6 No.275

<P><B>Stopping the Pain</B></P><P>Damage to the central or peripheral nervous system can trigger the development of neuropathic pain, which can manifest as painful sensations in response to stimuli that are not normally painful. Qiu <I>et al.</I> found that mice that had developed neuropathic pain after peripheral nerve injury showed changes in synaptic plasticity and increased abundance of synaptic NMDA receptors in the insular cortex, a region of the brain that is activated by acute and chronic pain. Using pharmacological inhibitors and transgenic mice, they mimicked these changes in vitro with insular cortical slices and thus identified the signaling pathway responsible. Mice injected with NMDA receptor inhibitors showed reduced behavioral signs of neuropathic pain after peripheral nerve injury. Thus, blocking NMDA receptor function in the insular cortex may prevent the development of neuropathic pain.</P>

High-risk Human Papillomavirus Genotypes in Cervical Lesions and Vaccination Challenges in China

Xu, Qiu-Xiang,Zhang, Zhen-Yu Asian Pacific Journal of Cancer Prevention 2015 Asian Pacific journal of cancer prevention Vol.16 No.6

Cervical cancer, mostly progressing from cervical intraepithelial neoplasia, is a major cause of morbidity and mortality in Chinese women. This is largely due to high prevalence of high-risk human papillomaviruses (hr-HPVs) in the population. The prevalence of hr-HPV DNA in women and in cervical lesions women ranged from 9.9% to 17.% and from 50.5% to 70.9% in different regions of China, respectively. The most common genotypes somewhat differ between regions throughout the country and from those in many other countries. This may be a challenge to cervical cancer screening and prevention in China. Combined detection of particular HPV genotypes should be recommended in all geographical regions in China and greater attention must be paid to specific hr-HPV types during cervical cancer screening and follow-up of cervical lesions. Besides, vaccination for prevention of cervical cancer by particular HPV genotypes, has not been introduced to China so far. Updated knowledge on prevalent HPV genotypes should be provided to public health organizations to help with the development of more effective HPV vaccines, which can protect Chinese women against HPV types prevalent in local China and thus have a substantial impact on the cervical cancer burden.

A Novel Method to Improve the Dispersibility of Silicon Nitride Powders in Aqueous Media

Bingjie Xu,Mengxing Li,Qi Chen,Pengfei Liu,Baosong Xu,Ben Qiu,Liang Xu,Zhao Han 성균관대학교(자연과학캠퍼스) 성균나노과학기술원 2019 NANO Vol.14 No.9

The present study describes a novel method to improve the dispersibility of silicon nitride powders in aqueous media. Specifically, a new Si3N4@g-C3N4 core–shell composite material was synthesized via annealing the mixture of silicon nitride and melamine under a nitrogen atmosphere using heating method. The effects of various initial mass ratios of Si3N4 and melamine on the structure and dispersibility of the composite were systematically investigated. The results of X-ray photoelectron spectroscopy and transmission electron microscope demonstrated that as-obtained Si3N4@g-C3N4 composite powders possess the core–shell structure, whereas the zeta potential and sedimentation analysis showed that they exhibit good dispersion in aqueous media. Furthermore, the colloidal dispersion of the composite powders is most stable when the initial mass ratio of Si3N4 and melamine is 100 : 3. The coated g-C3N4 could be completely removed in a cryogenic nitrogen atmosphere. The proposed process is expected to provide novel avenues for the study of dispersion of other inorganic powders.

Spectral Image Reconstruction of Chinese Ink and Wash Painting Based on Self-training with Multispectral Imaging

Peng Xu,Jueqin Qiu,Haisong Xu,Zhengnan Ye 한국색채학회 2017 AIC 2017 Jeju Vol.2017 No.10

The Chinese ink and wash painting is a special type of Chinese classic paintings. In this study, the spectral image of the Chinese ink and wash painting was reconstructed with multispectral imaging based on a self-training method. By partitioning the multispectral images of the painting with k-means clustering algorithm, the training samples are directly selected from the painting itself to restrain the deterioration of the spectral estimation caused by the material inconsistence between the training samples and the object painting in the conventional spectral reconstruction technique. In each cluster, only one sample which owns minimum mean distance to all the other samples residing in the cluster is chosen as the training sample. The spectral image of a Chinese ink and wash painting was reconstructed with a filter wheel based multispectral camera, indicating that the recovered spectral reflectance of the Chinese ink and wash painting based on this self-training method is more accurate than that based on the commercial color target.

Home-based traditional Chinese medicine nursing interventions for discharged patients with COVID-19: a rapid review of Chinese guidelines

Xiao Xu,Ya-Nan Shi,Rong-Yun Wang,Ting Liu,Jingming Xu,Wen Mao,Qiu-Hua Sun 한국한의학연구원 2020 Integrative Medicine Research Vol.9 No.3

Background: The aim of this review was to comprehensively summarize and analyze the current guidelines on home-based traditional Chinese medicine (TCM) nursing interventions for discharged patients with COVID-19. Methods: Eight data sources were searched until June 28, 2020. The frequency of home-based TCM nursing interventions and the use of specific acupuncture points recommended in Chinese guidelines for discharged COVID-19 patients were computed and analyzed. Results: In total, we identified 5 Chinese guidelines that provide for home-based TCM nursing interventions for discharged patients with COVID-19. Moxibustion and acupressure were singled out as the most frequently used intervention of the 11 home-based TCM nursing interventions recommended by these guidelines. RN12 and ST36 were the 2 most promoted acupuncture points for moxibustion and acupressure interventions for these patients. Conclusions: The present review showed the important role of home-based TCM nursing interventions for discharged COVID-19 patients. However, direct evidence of their efficacy is still insufficient.

Disorders of Small and Large Intestine : Colorectal Cancer In Guangdong Province: A Demographic And Anatomic Survey

( An Gao Xu ),( Bo Jiang ),( Zhi Jin Yu ),( Xin Ying Wang ),( Xu Hui Zhong ),( Ji Hong Liu ),( Li Shou Xiong ),( Qiu Yun Luo ),( Ai Hua Gan ) 대한소화기학회 2007 SIDDS Vol.9 No.-

Background/Aims: Colorectal cancer is the third leading incidence of malignant tumour in the world and the incidence of colorectal cancer has steadily been increasing in Asia in recently years. The aim of our study is to determine the basic demographic features of patients with colorectal cancer and the anatomic distribution and characteristics of the tumour in Guangdong population. Methods: A review of patients from 1990 to 2004 at five hospitals was conducted, including Peal Triangle Area in Guangdong (Nanfang Hospital and Huizhou Central People`s Hospital), North area of Guangdong (Shaoguan North-Guangdong People`s Hospital), West area of Guangdong (Affiliated Hospital Guangdong Medical Institute) and East area of Guangdong (Meizhou People`s Hospital). Results: Analysis was carried out on 6,501 patents, only 6,488 cases provided age. The age ranged from 5 years old to 91 years old and the mean age of 6,488 cases is 59. 5.2% (340/6,488) of the patients was young CRC patients. The peak incidence was between the ages 61 and 70 years old (29.5%). The mean age increases from 55 years old (1990-1992) to 61 years old (2002-2004) and the proportion of young CRC patients descends from 7.1% to 3.5%. The make to female ratio is 1.5:1 and the ratio increased with age increasing. Of 6,501 lesions, 3,423 (52.7%) were located in rectum and 3,078 (47.3%) in colon, the ratio of rectum cancer to colon cancer is 1.1:1. The proportion of rectum cancer decreased significantly from 74.5% (1990-1992) to 64.9% (2002-2004) and that of the right sides colon cancer increased from 25.5% to 35.1%. In four different areas, the mean age of CRC increasing and East area of Guangdong ranked the fist. There was no significant difference in the ratio of male to female. Conclusions: The demography of colorectal cancer in Guangdong is different from before and further study should be pursued to find the reason.

Bombyx mori used as a fast detection model of liver melanization after a clinical drug – Acetaminophen exposure

Yue He,Xu Xu,Jianfeng Qiu,Weimin Yin,Yang-Hu Sima,Shi-Qing Xu 한국응용곤충학회 2020 Journal of Asia-Pacific Entomology Vol.23 No.1

Acetaminophen (APAP) is an effective and widely used analgesic. However, APAP overdose is the principal cause of acute liver failure (ALF) in many countries. Here, we report the phenomenon of liver melanization which occurred before APAP-induced ALF in mice. A melanic surface induced by APAP which was time- and dosedependent in the silkworm invertebrate model was observed. In addition, an APAP-induced acute tissue failure model (ATF) was established using a metabolic detoxification tissue fat body which simulated mouse liver. An investigation of the anabolic mechanism of melanin in experimental animals showed that dopaquinone and dopamine which were synthesized from tyrosine via dopa in silkworms were further metabolized to melanin, while in mice, epinephrine was synthesized via the dopamine branch and melanin was only synthesized via the dopaquinone branch. On this basis, it is proposed that melanin-metabolic levels in plasma could be used as an early diagnostic marker of APAP overdose and the black spots on insect epidermis could be used as a fast detection model of toxicity.

피크전류모드 제어를 적용한 고주파 심부발열 전원장치 설계

허국성(Guo-Cheng Xu),정도(Tao Zheng),박성욱(Sheng-Xu Piao),구위경(Wei-Jing Qiu),김희제(Hee-Je Kim) 대한전기학회 2017 전기학회논문지 Vol.66 No.2

In this paper a prototype of high frequency heating power supply system based on the high frequency heating principle is designed to take the place of acupuncture, moxibustion, warm dressing treatment and some other traditional physical therapy methods. Which possess the advantages of low cost, convenient, easy operation and good effect. The high frequency heating power supply can generate a pulse voltage of more than 1KV with 300KHz switching frequency to heat the patient’s skin. The skin temperature can reach to 41~42℃. The peak current control method is used to maintain the skin temperature in the designed range. The design of the main circuit is based on the flyback converter topology. An easier and practical design method is proposed in this paper. The power supply system prototype is verified to be stable and reliable by both the simulation and experimental results.

Incorporation of Titanium into H-ZSM-5 Zeolite via Chemical Vapor Deposition: Effect of Steam Treatment

Xu, Cheng-Hua,Jin, Tai-Huan,Jhung, Sung-Hwa,Hwang, Jin-Soo,Chang, Jong-San,Qiu, Fa-Li,Park, Sang-Eon Korean Chemical Society 2004 Bulletin of the Korean Chemical Society Vol.25 No.5

Ti-ZSM-5 prepared by secondary synthesis, from the reaction of H-ZSM-5 with vapor phase $TiCl_4$, was characterized with several physicochemical techniques including FT-IR and UV/VIS-DRS. It was found that zeolite structure, surface area and pore volume did not change, and the framework aluminum could not be replaced by titanium atom during the secondary synthesis of Ti-ZSM-5. The incorporation of titanium into the framework might be due to reaction of $TiCl_4$with the silanol groups associated with defects or surface sites. The formation of extra-framework titanium could not be avoided, unless the samples were further treated by water vapor at 550 $^{\circ}C$ or higher temperature. High temperature steam treatment of Ti-ZSM-5 prepared by chemical vapor deposition with $TiCl_4$was efficient to prevent the formation of non-framework titanium species. Ti-ZSM-5 zeolites prepared in this work contained only framework titanium species and exhibited improved catalytic property close to TS-1 prepared by hydrothermal synthesis.