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- 저자 : Qingfeng Peng (검색결과 3 건)
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Development Issues of An ISG PM Machine and Control System
Xiaojiang Chen,Murray Edington,Roger Thornton,Yunzhou Fang,Qingfeng Peng 전력전자학회 2007 ICPE(ISPE)논문집 Vol.- No.-
This paper focuses on addressing some practical considerations in developing an ISG PM system for hybrid electric-vehicle (HEV) applications. Extensive practical test results and theoretical analyses are presented and analyzed. Firstly, the ISG PM machine design is discussed in term of the machine size, pole-pair number, permanent magnet flux, inductance, etc. A cost-effective machine design example, which was successfully demonstrated in a mild ISG HEV application, is analyzed. Its performance test results are evaluated. Subsequently, the impacts of the position sensors on the ISG performance are investigated exclusively. Three prominent position sensor candidates are studied in detail to examine their limitation and feasibility for ISG applications. Furthermore, the control related issues are discussed. The torque control of the ISG machine is implemented through vector control algorithm. Flux-weakening control is employed to achieve a wide speed range of constant-power operation. The impact of the inverter DC-link voltage variation is explored. In addition the digital control delay influence and its effective compensation strategy are addressed.
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DNMT1 mediates chemosensitivity by reducing methylation of miRNA-20a promoter in glioma cells
Daoyang Zhou,Yingfeng Wan,Dajiang Xie,Yirong Wang,Junhua Wei,Qingfeng Yan,Peng Lu,Lianjie Mo,Jixi Xie,Shuxu Yang,Xuchen Qi 생화학분자생물학회 2015 Experimental and molecular medicine Vol.47 No.-
Although methyltransferase has been recognized as a major element that governs the epigenetic regulation of the genome during temozolomide (TMZ) chemotherapy in glioblastoma multiforme (GBM) patients, its regulatory effect on glioblastoma chemoresistance has not been well defined. This study investigated whether DNA methyltransferase (DNMT) expression was associated with TMZ sensitivity in glioma cells and elucidated the underlying mechanism. DNMT expression was analyzed by western blotting. miR-20a promoter methylation was evaluated by methylation-specific PCR. Cell viability and apoptosis were assessed using the 3-(4,5-dimethyl-2-thiazolyl)-2,5-diphenyl-2-H-tetrazolium bromide (MTT) and TdT-mediated dUTP-biotin nick end labeling assays, respectively. The results showed that compared with parental U251 cells, DNMT1 expression was downregulated, miR-20a promoter methylation was attenuated and miR-20a levels were elevated in TMZ-resistant U251 cells. Methyltransferase inhibition by 5-aza-2′-deoxycytidine treatment reduced TMZ sensitivity in U251 cells. In U251/TM cells, DNMT1 expression was negatively correlated with miR-20a expression and positively correlated with TMZ sensitivity and leucine-rich repeats and immunoglobulin-like domains 1 expression; these effects were reversed by changes in miR-20a expression. DNMT1 overexpression induced an increase in U251/TM cell apoptosis that was inhibited by the miR-20a mimic, whereas DNMT1 silencing attenuated U251/TM cell apoptosis in a manner that was abrogated by miR-20a inhibitor treatment. Tumor growth of the U251/TM xenograft was inhibited by pcDNA-DNMT1 pretreatment and boosted by DNMT1-small hairpin RNA pretreatment. In summary, DNMT1 mediated chemosensitivity by reducing methylation of the microRNA-20a promoter in glioma cells.
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Huiqin Wang,Xiaoqing Yang,Jinzhao Zi,Mingjun Zhou,Zhefei Ye,Jinze Li,Qingfeng Guan,Peng Lv,Pengwei Huo,Yongsheng Yan 한국공업화학회 2016 Journal of Industrial and Engineering Chemistry Vol.35 No.-
Ag/AgCl/activated carbon (AC) plasmonic photocatalysts were prepared by precipitation and photoreduc-tion method. The as-prepared plasmonic photocatalysts were characterized by XRD, SEM, BET, EDS, UV–visDRS, XPS and PL. The results show the composite photocatalysts are successfully obtained and obviouslyexhibit surface plasmon resonance and effectively enhance the separation of h+/e . The photocatalyticdegradation rate of tetracycline (TC) could reach 97.3% in 60 min under visible light irradiation and cycledexperiments show stably photocatalytic activities. The active species analysis displays holes andsuperoxide radicals are the main reactive species. Photocatalytic kinetic indicates that the degradationprocesses obey pseudo first order kinetic equation.
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