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Mode III fracture analysis of piezoelectric materials by Trefftz BEM
Qin, Qing-Hua Techno-Press 2005 Structural Engineering and Mechanics, An Int'l Jou Vol.20 No.2
Applications of the Trefftz boundary element method (BEM) to anti-plane electroelastic problems are presented in this paper. Both direct and indirect methods with domain decomposition are discussed in details. Each crack is treated as semi-infinite thin slit defined in a subregion, for which a particular solution of the anti-plane problem, satisfying exactly the crack-face condition, is derived. The stress intensity factors defined at each crack tip can be directly computed from the coefficients of the particular solution. The performance of the proposed formulation is assessed by two examples and comparison is made with results obtained by other approaches. The Trefftz boundary element approach is demonstrated to be suitable for the analysis of the anti-plane problem of piezoelectric materials.
Han-Qin Shen,Zhuan-Qiang Yan,Fan-Gui Zeng,Chang-Tao Liao,Qing-Feng Zhou,Jian-Ping Qin,Qingmei Xie,Yingzuo Bi,Feng Chen 대한수의학회 2015 Journal of Veterinary Science Vol.16 No.3
As part of our ongoing influenza surveillance program in South China, 19 field strains of H9N2 subtype avian influenza viruses (AIVs) wereisolated from dead or diseased chicken flocks in Guangdong province, South China, between 2012 and 2013. Hemagglutinin (HA) genes ofthese strains were sequenced and analyzed and phylogenic analysis showed that 12 of the 19 isolates belonged to the lineage h9.4.2.5, whilethe other seven belonged to h9.4.2.6. Specifically, we found that all of the viruses isolated in 2013 belonged to lineage h9.4.2.5. The lineageh9.4.2.5 viruses contained a PSRSSR↓GLF motif at HA cleavage site, while the lineage h9.4.2.6 viruses contained a PARSSR↓GLF at thesame position. Most of the isolates in lineage h9.4.2.5 lost one potential glycosylation site at residues 200–202, and had an additional oneat residues 295–297 in HA1. Notably, 19 isolates had an amino acid exchange (Q226L) in the receptor binding site, which indicated that theviruses had potential affinity of binding to human like receptor. The present study shows the importance of continuing surveillance of newH9N2 strains to better prepare for the next epidemic or pandemic outbreak of H9N2 AIV infections in chicken flocks.
Genetic Effects of Polymorphisms in Myogenic Regulatory Factors on Chicken Muscle Fiber Traits
Yang, Zhi-Qin,Qing, Ying,Zhu, Qing,Zhao, Xiao-Ling,Wang, Yan,Li, Di-Yan,Liu, Yi-Ping,Yin, Hua-Dong Asian Australasian Association of Animal Productio 2015 Animal Bioscience Vol.28 No.6
The myogenic regulatory factors is a family of transcription factors that play a key role in the development of skeletal muscle fibers, which are the main factors to affect the meat taste and texture. In the present study, we performed candidate gene analysis to identify single-nucleotide polymorphisms in the MyoD, Myf5, MyoG, and Mrf4 genes using polymerase chain reaction-single strand conformation polymorphism in 360 Erlang Mountain Chickens from three different housing systems (cage, pen, and free-range). The general linear model procedure was used to estimate the statistical significance of association between combined genotypes and muscle fiber traits of chickens. Two polymorphisms (g.39928301T>G and g.11579368C>T) were detected in the Mrf4 and MyoD gene, respectively. The diameters of thigh and pectoralis muscle fibers were higher in birds with the combined genotypes of GG-TT and TTCT (p<0.05). Moreover, the interaction between housing system and combined genotypes has no significant effect on the traits of muscle fiber (p>0.05). Our findings suggest that the combined genotypes of TT-CT and GG-TT might be advantageous for muscle fiber traits, and could be the potential genetic markers for breeding program in Erlang Mountain Chickens.
Guang-chong Qin,Tao Lan,Qing Qin,Shan-hua Xu,Zong-xing Zhang 대한토목학회 2019 KSCE JOURNAL OF CIVIL ENGINEERING Vol.23 No.8
The cross section would be reduced and the material properties of the steel structure would be deteriorated under the corrosion environment, which will have different effects on the earthquake resistant behavior. This paper takes corroded H-steel column as the research object. Firstly, the influence on the failure mode, bearing capacity, hysteretic properties, ductility and hysteretic energy is analyzed from specific factors which consist of different width-to-thickness on flange, different height-to-thickness on web and different axial compression ratios by FEA. The results show that, the area of the hysteresis loop diminishes gradually, the bearing capacity decrease clearly, the accumulative energy dissipation and ductility coefficient decreased continuously, and the degradation laws of buckling load, peak load, hysteretic energy and ductility coefficient of corroded H-steel columns are thereby established. When the thickness of flange decreased by 30%, the peak load decreased by 32% and hysteretic energy decreased by 77%. However, the peak load decreased by 14% and hysteretic energy decreased by 40% when the thickness of web decreased by 30%. When the axial compression ratio is 0.6, and the mass loss ratio of corroded H-steel columns reached 22%, the peak load and hysteretic energy decreased by 28% and 51% respectively. Secondly, the hysteretic model of load-displacement of corroded H-steel members under cyclic loading is proposed based on the simulation results and the degradation model of characteristic point of skeleton line was given. Finally, the evaluation criteria are proposed based on the seismic performance objectives, and the classification of failure types as well as the overall performance evaluation of corroded steel members are carried out.
Cui, Yan-Hui,Liang, Hai-Jun,Zhang, Qing-Qin,Li, Si-Qing,Li, Xiao-Rui,Huo, Xiao-Qing,Yang, Qing-Hui,Li, Wei-Wei,Gu, Jian-Fa,Hua, Qin-Liang,Lu, Ping,Miao, Zhan-Hui Asian Pacific Journal of Cancer Prevention 2012 Asian Pacific journal of cancer prevention Vol.13 No.4
Objective: To explore the effect on radiosensitivity of arsenic trioxide ($As_20_3$) in conjunction with hyperthermia on the esophageal carcinoma EC-1 cell line. Method: Inhibition of EC-1 cell proliferation at different concentrations of $As_20_3$ was assessed using the methyl thiazolyl blue colorimetric method (MTT method), with calculation of $IC_{50}$ value and choice of 20% of the $IC_{50}$ as the experimental drug concentration. Blank control, $As_20_3$, hyperthermia, radiotherapy group, $As_20_3$ + hyperthermia, $As_20_3$ + radiotherapy, hyperthermia + radiotherapy and $As_20_3$ + hyperthermia + radiotherapy groups were established, and the cell survival fraction (SF) was calculated from flat panel colony forming analysis, and fitted by the 'multitarget click mathematical model'. Flow cytometry (FCM) was used to detect changes in cell apoptosis and the cell cycle. Results: $As_20_3$ exerted inhibitory effects on proliferation of esophageal carcinoma EC-1 cells, with an $IC_{50}$ of 18.7 ${\mu}mol/L$. After joint therapy of $As_20_3$ + hyperthermia + radiotherapy, the results of FCM showed that cells could be arrested in the $G_2$/M phase, and as the ratio of cells in $G_0/G_1$ and S phases decreased, cell death became more pronounced. Conclusion: $As_20_3$ and hyperthermia exert radiosensitivity effects on esophageal carcinoma EC-1 cells, with synergy in combination. Mechanistically, $As_20_3$ and hyperthermia mainly influence the cell cycle distribution of EC-1 esophageal carcinoma cells, decreasing the repair of sublethal damage and inducing apoptosis, thereby enhancing the killing effects of radioactive rays.
He, Feng,Wen, Hai-Shen,Li, Ji-Fang,Yu, Da-Hui,Ma, Rui-Qin,Shi, Dan,Mu, Wei-Jie,Zhang, Yuan-Qing,Hu, Jian,Liu, Miao,Han, Wei-Guo,Zhang, Jia-Nan,Wang, Qing-Qing,Yuan, Yu-Ren,Liu, Qun Asian Australasian Association of Animal Productio 2011 Animal Bioscience Vol.24 No.4
Gonadotropin-releasing hormone receptor (GnRHR) gene is expressed at the anterior pituitary gland and plays a key role in gonad development. This study aimed to investigate molecular genetic characteristics of the GnRHR gene and elucidate the effects of single nucleotide polymorphisms (SNPs) of GnRHR gene on sex steroid level in Japanese flounder (Paralichthys olivaceus). We used polymerase chain reaction single-strand conformation polymorphism (PCR-SSCP) and sequencing of the GnRHR gene in 75 individuals. We identified three SNPs in the GnRHR gene: P1 locus (C759A and C830T) in the coding region of exon2 which were both linked together and P2 locus (G984T) in the coding region of exon3, which added a new transcript factor (ADR1) and a new methylation site (CG). Only C830T of P1 leads to amino acid changes Thr266Ile. Statistical analysis showed that P1 was significantly associated with $17{\beta}$-estradiol ($E_2$) level (p<0.01) and gonadosomatic index (GSI) (p<0.05). Individuals with genotype BB of P1 had significantly higher serum $E_2$ levels (p<0.01) and GSI (p<0.05) than those of genotype AA or AB. Another SNP, P2, synonymous mutation, was significantly associated with GSI (p<0.05). Individuals with genotype AB of P2 had significantly higher GSI (p<0.05) than that of genotype AA. In addition, there was a significant association between one diplotype based on three SNPs and reproductive traits. The genetic effects for both serum $E_2$ level and GSI of diplotype D4 were super diplotypes (p<0.05). These results suggest that the SNPs in Japanese Flounder GnRHR are associated with $E_2$ level and GSI.
Control Strategy for Buck DC/DC Converter Based on Two-dimensional Hybrid Cloud Model
Qing-Yu Wang,Ren-Xi Gong,Li-Wen Qin,Zhao-He Feng 대한전기학회 2016 Journal of Electrical Engineering & Technology Vol.11 No.6
In order to adapt the fast dynamic performances of Buck DC/DC converter, and reduce the influence on converter performance owing to uncertain factors such as the disturbances of parameters and load, a control strategy based on two-dimensional hybrid cloud model is proposed. Firstly, two cloud models corresponding to the specific control inputs are determined by maximum determination approach, respectively, and then a control rule decided by the two cloud models is selected by a rule selector, finally, according to the reasoning structure of the rule, the control increment is calculated out by a two-dimensional hybrid cloud decision module. Both the simulation and experiment results show that the strategy can dramatically improve the dynamic performances of the converter, and enhance the adaptive ability to resist the random disturbances, and its control effect is superior to that of the current-mode control.
A New Overlap Current Restraining Method for Current-source Rectifier
Qin, Haihong,Liu, Qing,Zhang, Ying,Zhang, Xin,Wang, Dan The Korean Institute of Power Electronics 2018 JOURNAL OF POWER ELECTRONICS Vol.18 No.2
To ensure a DC current path and avoid large voltage overshoot of the DC-link inductor, alternating PWM pulses in the current-source rectifier should be supplemented by overlap time, which generates an overlap current and causes input current distortion. In this study, the influence of overlap time is illustrated by comparing the AC-side current before and after overlap time is added. The overlap current distribution caused by overlap time is discussed under different modulation carriers, including triangle carrier, positive-going carrier, and negative-going carrier. The quantitative relationship between the extra harmonics of the AC-side current and overlap time is based on the Fourier analysis. Based on the commutation analysis, a new carrier modulation scheme that can restrain overlap current is proposed. A 3 kW prototype is established to verify the effectiveness of the influence of overlap time and the proposed restraining modulation scheme.