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( Hua Qi Pan ),( Su Ya Yu ),( Chun Feng Song ),( Nan Wang ),( Hui Ming Hua ),( Jiang Chun Hu ),( Shu Jin Wang ) 한국미생물 · 생명공학회 2015 Journal of microbiology and biotechnology Vol.25 No.3
A new actinomycete strain NA4 was isolated from a deep-sea sediment collected from the South China Sea and showed promising antifungal activities against soilborne fungal pathogens. It was identified as Streptomyces cavourensis by morphological, physiological, and phylogenetic analyses based on its 16S rRNA gene sequence. The main antifungal components were isolated and identified from the fermentation culture as bafilomycins B1 and C1. These compounds exhibited significant antifungal activities and a broad antifungal spectrum. The results suggest that the Streptomyces cavourensis NA4 and bafilomycins B1 and C1 could be used as potential biocontrol agents for soilborne fungal diseases of plants.
Yi Ling Qi,Xu Chun Song,Yi Fan Zheng 성균관대학교(자연과학캠퍼스) 성균나노과학기술원 2017 NANO Vol.12 No.3
Novel heterostructure BiOI/BiOIO3 nanocomposites were successfully prepared through a facile deposition method at room temperature. BiOIO3 is a noncentrosymmetric compound that has an internal self-built electric field. BiOI was applied as a visible light absorber to sensitize semiconductors owing to its smallest bandgap. The coupling between BiOIO3 and BiOI can combine their advantages and improve photocatalytic properties. Compared with the single BiOI and BiOIO3, the heterostructure BiOI/BiOIO3 nanocomposites displayed a significantly enhanced photocatalytic activity for the Rhodamine B (RhB) degradation. The enhanced photocatalytic performance is deduced closely related to the formation of BiOI/BiOIO3 heterojunction interface whose presence is regarded to be a favorable factor for the transfer and separation of the photogenerated electrons and holes.
Liu Yan-qi,Zhang Yan,Song Chun-fang,Huangsen Gu,Longlong Xu 대한기계학회 2019 JOURNAL OF MECHANICAL SCIENCE AND TECHNOLOGY Vol.33 No.1
The dynamic response of a track structure under a uniform-speed moving harmonic load is researched according to dynamic response characteristics of a periodic structure under moving harmonic load in the frequency domain. The track was assumed as a simple Euler beam model periodically supported by continuous discrete point, and mathematical model of the dynamic differential equation of vertical vibration for the track structure is built. Then, the analytical equation for the dynamic response of any point on the track structure is concluded in the frequency domain for the following research. The dynamic responses of the track structure under the uniform-speed moving harmonic load are investigated using the theory of infinite periodic structure. Finally, the effects of excitation frequency, fastener stiffness, fastener damping, and speed of the moving harmonic load on the dynamic response of the track structure are studied. Results indicate that the response peaks of the rail under moving harmonic load occur near the excitation frequency, and the dynamic response decreases rapidly in the area far from the excitation frequency. The response peaks of the rail will move slightly toward a high frequency with the increase in the excitation frequency. The increase in the fastener stiffness will lead to improvement of the dynamic response of the rail in the nonresonant region at a high frequency, equivalent to the high rigidity of the rail fastener and intense vibration of the rail. The changes in fastener damping exert no significant effect on the resonant peak and peak bandwidth of the system. The fastener damping plays a significant role in restraining the vibration at a high frequency. The strong vibration of the track structure can be effectively controlled by an increase in the damping.
Feng, Xiao-Dong,Song, Qi,Li, Chuan-Wei,Chen, Jian,Tang, Hua-Mei,Peng, Zhi-Hai,Wang, Xue-Chun Asian Pacific Journal of Cancer Prevention 2014 Asian Pacific journal of cancer prevention Vol.15 No.21
Background: Structural maintenance of chromosomes 4 (SMC-4) is a chromosomal ATPase which plays an important role in regulate chromosome assembly and segregation. However, the role of SMC-4 in the incidence of malignancies, especially colorectal cancer is still poorly understood. Materials and Methods: We here used quantitative PCR and Western blot analysis to examine SMC-4 mRNA and protein levels in primary colorectal cancer and paired normal colonic mucosa. SMC-4 clinicopathological significance was assessed by immunohistochemical staining in a tissue microarray (TMA) in which 118 cases of primary colorectal cancer were paired with noncancerous tissue. The biological function of SMC-4 knockdown was measured by CCK8 and plate colony formation assays. Fluorescence detection has been used to detect cell cycling and apoptosis. Results: SMC-4 expression was significantly higher in colorectal cancer and associated with T stage, N stage, AJCC stage and differentiation. Knockdown of SMC-4 expression significantly suppressed the proliferation of cancer cells and degraded its malignant degree. Conclusions: Our clinical and experimental data suggest that SMC-4 may contribute to the progression of colorectal carcinogenesis. Our study provides a new therapeutic target for colorectal cancer treatment.
Primary Research on Theoretical Performance and Powder Supply Characteristics of Powder Rocket
Deng, Zhe,Hu, Chun-bo,Hu, Song-qi,Xu, Yi-hua The Society for Aerospace System Engineering 2015 International Journal of Aerospace System Engineer Vol.2 No.2
The powder propellant rocket which uses micron-sized particles as fuel is storable and costly. Functions like thrust control and multiple-ignition can be realized by changing powder mass flow rate. In this paper, we discuss the theoretical performance of bi-propellant and mono-propellant powder rocket. When used as the fluidization gas, helium can improve specific impulse dramatically. The stability of the powder feeding device is preliminarily quantified through metal/N2O powder rocket hot fire tests.
Shikang Zhao,Wei Liu,Shuo Li,Tao Shi,Qiusong Chen,Qi Li,Leina Sun,Dian Ren,Zuoqing Song,Chun Huang,Song Xu 대한암학회 2021 Cancer Research and Treatment Vol.53 No.2
A 61-year-old male patient was simultaneously diagnosed with lung adenocarcinoma and inflammatory myofibroblastic tumor (IMT). The lung adenocarcinoma and IMT harbored two distinct types of ALK translocation, LOC101927285-ALK, and TPM3-ALK, respectively. The ALK Ventana showed strong positivity on both lesions. The patient was therefore given an endobronchial cryotherapy and ALK inhibitor crizotinib. The tumors showed durable response however the left lung adenocarcinoma relapsed at 17th month post-crizotinib treatment. Tissue re-biopsy on the resistant tumor revealed an ALK exon 23 C1156Y missense mutation in addition to LOC101927285-ALK mutation. Further RNA-based sequence uncovered that the noncoding region rearrangement is the fusion mutation of EML4-ALK. The patient was therefore received alectinib, and the tumor exhibited partly response. Overall, it is very rare that two types of pulmonary tumors exist in one patient driven by two distinct ALK fusions, which emphasizes the necessity of gene sequencing in clinical decision-making and individualized therapy.
Kaixian Ba,Bin Yu,Xiangdong Kong,Hua-Long Zhao,Jin-Song Zhao,Qi-Xin Zhu,Chun-He Li 제어·로봇·시스템학회 2017 International Journal of Control, Automation, and Vol.15 No.4
The highly integrated valve-controlled cylinder (HIVC) is the joint driver in the hydraulic drive leggedrobot motion process, with the inner-loop-control-based outer loop dynamic compliance control method of the hydraulicsystem adopted. Yet the dynamic compliance of the HIVC position inner loop control has effects on theaccuracy of the outer loop dynamic compliance control. Therefore, the dynamic compliance parallel compositiontheory of the HIVC position inner loop control is presented and its dynamic compliance is analyzed in this paper,based on the HIVC position control nonlinear mathematical model. Moreover, the multiple parallel branch dynamiccompliance compound compensation control method is also designed and the dynamic compliance parallel compositionis rearranged. The experimental results indicate that adopting the compensation control method can decreasethe dynamic compliance of the HIVC position control system dramatically, which would provide the inner loopdynamic compliance compensation control method of the robot with high accuracy and high robustness.