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RISS 인기검색어
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- 저자 : Qi’an Peng (검색결과 3 건)
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Peng Liu,Wei Qi,Wenzhen An,Longlong Tian,Zhan Li,Xiaolei Chen,Wang-Suo Wu 성균관대학교(자연과학캠퍼스) 성균나노과학기술원 2015 NANO Vol.10 No.3
As is well-known, porous nanomaterials have attracted increasing attention recently, and graphene-related materials (such as porous graphene) have been studied both experimentally and theoretically. Almost all researches are focused on nanoelectronics, supercapacitors, multifunctional membrances, bio-applications or others. Consequently, in order to understand the differences between porous graphene and normal graphene at adsorption and catalytic property, in this experiment, with the removal of metal ion (152Eu(III)) and organic matter (gallic acid) and reduction of 4-nitrophenol (4-NP) by NaBH4 as model reactions, a systematic investigation into the adsorptive performance as well as catalytic activity of graphene with or without electron beam irradiation exposure had been carried out. As the results showed, compared with the reduction of pristine graphene oxidized (R-GO), the reduction of graphene oxidized with electron beam irradiation exposure (100 MGy, about 2 h, radiation graphene oxide (R-RGO)) had many irregular defects caused by lack of atoms; the adsorptive performance of the R-RGO increased for metals but decreased for organic matter. However, the adsorption rate of the R-RGO was lower for metals, but higher for organic matter than that of the R-GO. In addition, the results also showed that the R-RGO had a better catalytic capacity than the R-GO.
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Fei Li,Sanmin Wang,Peng Chen,Zhibin Li,Linlin Li,Qi’an Peng 대한기계학회 2022 JOURNAL OF MECHANICAL SCIENCE AND TECHNOLOGY Vol.36 No.7
A multi-objective variable parameter optimization method that considers meshing efficiency and contact performance simultaneously is proposed to optimize the tooth surface of spiral bevel gears to achieve higher contact performance and transmission efficiency. First, the tooth surface equations of the spiral bevel gear are established in line with the gear cutting process, and the deviation of tooth surface is analyzed and controlled. Second, the machine tool parameters with the greatest impact on the tooth surface are selected on the basis of the sensitivity analysis approach as the optimization design variables, and the relationship between the machine tool parameters, contact performance, and meshing efficiency is established. Third, the multi-objective variable parameter optimization algorithm is applied to determine the final optimal machine parameters, and the multi-objective optimization algorithm for the tooth surface of spiral bevel gear is formed. Finally, the correctness and effectiveness of the algorithm are verified by numerical simulation and experiment.
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Jingcui Yu,Songbin Fu,Peng Liu,Xiaobo Cui,Yu Sui,Guohua Ji,Rongwei Guan,Donglin Sun,Wei Ji,Fangli Liu,An Liu,Yuzhen Zhao,Yang Yu,Yan Jin,Jing Bai,Jingshu Geng,Yingwei Xue,Jiping Qi,Ki-Young Lee 한국분자세포생물학회 2011 Molecules and cells Vol.32 No.1
Previously, we identified 3 overlapping regions showing loss of heterozygosity (LOH, R_1-R_3 from 11 to 30 cM) on chromosome 17 in 45 primary gastric cancers (GCs). The data indicated the presence of tumor suppressor genes (TSGs) on chromosome 17 involved in GC. Among the putative TSGs in these regions, HIC1 (in SR_1) and TOB1 (in SR_3) remain to be examined in GC. By immunohistochemistry (IHC), methylation-specific PCR (MSP) and western blot, we evaluated the expression and regulation status for HIC1 and TOB1 protein in GC. We narrowed down the deletion intervals on chromosome 17 and defined five smaller LOH subregions, SR_1-SR_5 (0.54 to 3.42 cM), in GC. We found that HIC1 had downregulated expression in 86% (91/106) and was methylated in 87% (26/30) of primary GCs. Of the primary GCs showing downregulation of HIC1 protein, 75% (18/24) had methylated HIC1 gene. TOB1 was either absent or expressed at reduced levels in 75% (73/97) of the GC samples. In addition, a general reduction was found in total and the ratio of unphosphorylated to phosphorylated TOB1 protein levels in the differentiated GC cell lines. Further analysis revealed significant simultaneous downregulation of both HIC1 and TOB1 protein in GC tissue microarray samples (67%, 52/78) and in primary GCs (65%, 11/17). These results indicate that silencing of HIC1 and TOB1 expression is a common occurrence in GC and may contribute to the development and progression of the disease.
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