http://chineseinput.net/에서 pinyin(병음)방식으로 중국어를 변환할 수 있습니다.
변환된 중국어를 복사하여 사용하시면 됩니다.
Paulo Gustavo Kotze,Daniela Oliveira Magro,Barbara Saab,Mansur Paulo Saab,Lilian Vital Pinheiro,Marcia Olandoski,Maria de Lourdes Setsuko Ayrizono,Carlos Augusto Real Martinez,Claudio Saddy Rodrigues 대한장연구학회 2018 Intestinal Research Vol.16 No.1
Background/Aims: The use of anti-tumor necrosis factor (anti-TNF) agents seems to reduce surgical rates and delay surgicalprocedures in prospective trials and population-based studies in the management of Crohn’s disease (CD). This study aimedto identify whether preoperative anti-TNF agents influence the time from diagnosis to surgery. Methods: An observationalretrospective cohort study was conducted on patients with CD submitted to intestinal resections due to complications ormedical therapy failure in a period of 7 years. The patients were allocated into 2 groups according to their previous exposure toanti-TNF agents in the preoperative period. Epidemiological aspects regarding age at diagnosis, smoking, perianal disease, andpreoperative conventional therapy were considered. A Kaplan-Meier survival analysis was used to outline possible differencesbetween the groups regarding the time to surgery. Results: A total of 123 patients were included (71 and 52 with and withoutprevious exposure to biologics, respectively). The overall time to surgery was 108±6.9 months (maximum, 276 months). The survival estimation revealed no difference in the mean time to intestinal resection between the groups (99.78±10.62 months inthe patients without and 114.01±9.07 months in those with previous anti-TNF use) (log-rank P =0.35). There was no significantdifference in the time to surgery regarding perianal CD (P =0.49), smoking (P =0.63), preoperative azathioprine (P =0.073) andsteroid use (P =0.58). Conclusions: The time from diagnosis to surgery was not influenced by the preoperative use of anti-TNFtherapy in this cohort of patients.
Paulo S. André,Ant?io L. Teixeira,Armando N. Pinto,Lara P. Pellegrino,Berta B. Neto,J?e F Rocha,Jo? L. Pinto,Paulo N. Monteiro 한국전자통신연구원 2006 ETRI Journal Vol.28 No.2
In this letter, we will evaluate the performance degradation of a 40 km high-speed (40 Gb/s) optical system, induced by optical fiber variations of the chromatic dispersion induced by temperature changes. The chromatic dispersion temperature sensitivity will be estimated based on the signal quality parameters.
A Heart Rate Variability-based Smart Approach to Analyze Frailty in Older Adults
Joao Paulo do Vale Madeiro,Paulo Cesar Cortez,Arnaldo Aires Peixoto Junior,Joao Alexandre Lobo Marques,Antonio Alisson Pessoa Guimara,John Hebert da Silva Felix 한국산학기술학회 2015 SmartCR Vol.5 No.4
This paper presents an algorithm that applies metrics derived from automatic QRS detection and segmentation in electrocardiogram signals for analyzing Heart Rate Variability to study the evolution of metrics in the frequency domain of a clinical procedure. The analysis was performed on three sets of elderly people, who are categorized according to frailty phenotype. The first set was comprised of frail elderly, the second pre-frail elderly, and the third robust elderly. Investigators from many disciplines have been encouraged to contribute to the understanding of molecular and physiological changes in multiple systems that may increase the vulnerability of frail elderly. In this work, the frailty phenotype can be characterized by unintentional weight loss, as self-reported, fatigue assessed by self-report, grip strength (measured directly), physical activity level assessed by self-report and gait speed (measured). The results obtained demonstrate the existence of significant differences between Heart Rate Variability metrics for the three groups, especially considering a higher preponderance for sympathetic nervous system for the group of robust patients in response to postural maneuver.
Experimental and numerical study of headed bars embedded in RC members under tension
Paulo F.M. Santana,Patricia C.S. Silva,Mauricio P. Ferreira,Luciano M. Bezerra,Marcos H. Oliveira 국제구조공학회 2022 Structural Engineering and Mechanics, An Int'l Jou Vol.84 No.4
Headed bars are often used when there is insufficient space for a straight or curved bar to be fully developed to ensure the transference of forces between steel and concrete in several types of connections between structural members. In such cases, the concrete breakout strength of the headed bars can be a critical point of the design and must be considered appropriately. This paper evaluates the tensile strength of headed bars embedded in reinforced concrete members, failing due to concrete breakout. Four experimental tests on headed bars embedded in slender concrete members are presented and discussed, showing that strength previsions from the design codes can be significantly conservative as they ignore the contribution from the flexural reinforcement. 3D finite element models were developed using Abaqus Unified FEA to simulate the tested specimens, and it was observed that they were able to reproduce the formation of the concrete cone accurately, besides the response and resistance observed in tests. Furthermore, the experimental, numerical, and design code resistances are compared and discussed. A new equation to evaluate the concrete cone strength of the tested headed bars is proposed, which takes into account parameters not explicitly considered in the current design equations.
Intramammary sentinel lymph node with capsular extravasation in breast cancer
Paulo Roberto De Alcantara Fil,Carla Curi,Camila Souza Guatelli,Cynthia Aparecida B. de Toledo,Stephania Martins Bezerra,Fernando Augusto Soares,Fabiana Baroni Makdissi 대한외과학회 2017 Annals of Surgical Treatment and Research(ASRT) Vol.92 No.5
Sentinel lymph node biopsy has been developed as the standard of treatment in breast cancer. Status of axillary sentinel lymph node is known to be a significant prognostic factor. Nevertheless, involvement of an intramammary lymph node with metastasis in breast cancer is a rare radiological and clinical presentation, and with extracapsular extravasation even more uncommon. Historically, reported series of patients with intramammary lymph node diagnosed by final histological examination are small in number and clinical significance of metastasis is still unclear. Here, we report a case of conservative breast cancer surgery with 3 intramammary sentinel lymph nodes containing metastasis and extracapsular extravasation. After multidisciplinary consensus, the patient was surgically reapproached with mastectomy. Even though the 3 intramammary sentinel lymph nodes were positive for metastases, pathology examination did not reveal any signs of malignancy in the mastectomy specimen.
Paulo B. Gonçalves,Daniel Leonardo B.R. Jurjo,Carlos Magluta,Ney Roitman 국제구조공학회 2013 Structural Engineering and Mechanics, An Int'l Jou Vol.46 No.6
This work presents an experimental methodology specially developed for the nonlinear largeamplitude free vibration analysis of a clamped-free thin-walled metal column under self-weight. The main contribution of this paper is related to the developed experimental methodology which is based on a remote sensing technique using a computer vision system that integrates, on-line, the digital image acquisition and its treatment through special image processing routines. The main importance of this methodology is that it performs large deflections measurements without making contact with the structure and thus, not introducing undesirable changes in its behavior, for instance, appreciable changes in mass and stiffness properties. This structure presents, in most cases, highly non-linear responses, which cannot be reproduced by conventional finite-element softwares due, mainly, to the simultaneous influence of geometric and inertial non-linearities. To capture the non-linearities associated with large amplitude vibration and be able to describe the buckling process, the structure is discretized as a sequence of jointed coupled elastic pendulums. The obtained numerical results are favorably compared with the experimental ones, in the preand post-buckling regimes.
Preoperative use of anti-tumor necrosis factor therapy in Crohn`s disease: promises and pitfalls
( Paulo Gustavo Kotze ),( Subrata Ghosh ),( Willem A. Bemelman ),( Remo Panaccione ) 대한장연구학회 2017 Intestinal Research Vol.15 No.2
Recent advances in medical and surgical therapy were achieved during the last two decades in the management of Crohn`s disease (CD). Anti-tumor necrosis factor (anti-TNF) agents are widely used worldwide. However, a significant proportion of patients still need surgical resections. The impact of previous exposure to these agents on the perioperative and postoperative outcomes is still controversial. In this critical review, we aimed to position the strategy of intentional preoperative use of anti- TNF agents in the management of CD. The indications and contraindications for this strategy are detailed, and despite scarce evidence, the possible advantages and disadvantages of the intentional use of anti-TNF agents before abdominal surgery in CD are discussed. (Intest Res 2017;15:160-165)
Paulo A. Augusto,Teresa Castelo-Grande,Pedro Augusto,Domingos Barbosa,A.M. Est?vez 한국물리학회 2007 Current Applied Physics Vol.7 No.3
A new device, MAGCLATMoped by the authors. In a previous article the equations of movement for non-magnetic particles in this new device were analyzed and inthis paper the limiting conditions set by the dierent variables and equations of movement are presented for the case of the non-magneticparticles. The knowledge of these limiting conditions is important as they set the boundaries within which we may manipulate theMAGCLATM’s operating and design variables.
Supervised Teaching Practice in Initial Teacher Education of Early Childhood Teachers in Portugal
Paulo Viana,Marta Abelha,Helena Inês,Patrícia Gramaxo,Filipa Seabra The Pacific Early Childhood Education Research Ass 2023 Asia-Pacific journal of research in early childhoo Vol.17 No.3
Supervised teaching practice (STP) is a fundamental stage of initial teacher education, including preschool educators and teachers of the first cycle of basic education (1st CBE), which impacts their future practices. Our objectives were: a) to characterize STP in the curricula of degrees habilitating teachers for preschool education and teaching of the 1st CBE; b) to gather indicators about the process of STP implemented by the same cycles of studies; and c) to describe the improvement recommendations by the Agency for Evaluation and Accreditation of Higher Education (A3ES) to the same cycles of studies, concerning STP. The study was based on the documentary analysis of the plans of study, and A3ES reports on the initial teacher education programs preparing preschool educators and teachers of the 1st CBE of public higher education institutions (HEI) in Portugal, available during the academic year of 2020/2021. The results point to discrepancies in the definition of contact hours and the number of hours dedicated to supervised teaching practice across HEI. The recommendations for improvement by the A3ES about STP encompass cooperating teachers, the accompaniment by the HEI, and the conditions of reception at the cooperating schools.