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Jonathan Paquette,Di Wang,Won Min Seo 국립민속박물관 2019 International Journal of Intangible Heritage Vol.14 No.-
Public housing is an important facet of social life in HongKong. Nearly half the population benefits from living in apublicly subsidised unit. In recent years, strategies havebeen put in place to preserve the architectural heritage ofpublic housing in Hong Kong. Similarly, other strategiestargeted the safeguarding, the valuation, and promotion oflife in the public estates in the 1950s, 1960s, and 1970s asa manifestation of intangible heritage, and symbol of HongKong’s identity. Memories of public housing contribute topreserving and promoting a form of intangible heritagethat is remembered across Hong Kong’s various heritageinstitutions. Over the last decade, many projects haveattempted to engage with the ethos of life in publicestates through different ambitious exhibitions and siteredevelopment projects. After reviewing the differentstrategies put in place to engage with the intangibleheritage of early life in public housing, this paper reviewsthe technical challenges and the ethical dimensionsassociated with the preservation and valuation of this typeof intangible heritage.
Picard, Nathalie,Ali, Hasrat,Van Lier, Johan E.,Klarskov, Klaus,Paquette, Benoit Korean Society of Photoscience 2009 Photochemical & photobiological sciences Vol.8 No.2
With the aim to develop improved dual-action sensitizers suitable for both photodynamic therapy (PDT) and radiotherapy, we prepared a series of metal and metal-free cationic porphyrins, brominated either on $\beta$- or N-allyl positions. Photo- and radiosensitizing efficacy was evaluated in MDA-MB-231 breast cancer cells incubated with $1\;{\mu}M$ porphyrin and treated with graded doses of visible light or 0.6 Gy of $^{60}Co$ gamma irradiation. Metabolic activity after PDT or cell survival after gamma irradiation were estimated by a colorimetric (MTT) or clonogenicity assay, respectively. The highest photo- and radiosensitizing activities were observed with the porphyrins substituted with bromines on N-allyl positions. The non-metalated N-allyl bromoporphyrin exhibited the highest photocytotoxicity ($LD_{50}=4.1{\pm}0.6\;J\;cm^{-2}$, compared to $15.3{\pm}2.2\;J\;cm^{-2}$ for the non-brominated analog). The radiosensitizing capacity of the cationic porphyrins was also affected by these substitutions with the non-metalated N-allyl bromo analog showing the best improvement ($LD_{50}=1.2{\pm}0.4\;Gy$ vs. $3.6{\pm}0.9\;Gy$ for the non-brominated analog). The increased photodynamic and radiosensitizing potencies due to bromine addition hold potential for the development of new, improved drugs for cancer treatment in combination with photodynamic and radiation therapy.
Positive biodiversity-productivity relationship predominant in global forests
Liang, Jingjing,Crowther, Thomas W.,Picard, Nicolas,Wiser, Susan,Zhou, Mo,Alberti, Giorgio,Schulze, Ernst-Detlef,McGuire, A. David,Bozzato, Fabio,Pretzsch, Hans,de-Miguel, Sergio,Paquette, Alain,H&eac American Association for the Advancement of Scienc 2016 Science Vol.354 No.6309
<P>The biodiversity-productivity relationship (BPR) is foundational to our understanding of the global extinction crisis and its impacts on ecosystem functioning. Understanding BPR is critical for the accurate valuation and effective conservation of biodiversity. Using ground-sourced data from 777,126 permanent plots, spanning 44 countries and most terrestrial biomes, we reveal a globally consistent positive concave-down BPR, showing that continued biodiversity loss would result in an accelerating decline in forest productivity worldwide. The value of biodiversity in maintaining commercial forest productivity alone-US$166 billion to 490 billion per year according to our estimation-is more than twice what it would cost to implement effective global conservation. This highlights the need for a worldwide reassessment of biodiversity values, forest management strategies, and conservation priorities.</P>