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      • SCOPUSKCI등재

        Unsafe Disposal of Child Faeces: A Community-based Study in a Rural Block in West Bengal, India

        PS, Preeti,Sahoo, Sanjaya Kumar,Biswas, Dhiraj,Dasgupta, Aparajita The Korean Society for Preventive Medicine 2016 Journal of Preventive Medicine and Public Health Vol.49 No.5

        Objectives: A clean India is the responsibility of all Indians. One of the objectives of the Swachh Bharat Abhiyan (Clean India Initiative) is to bring about behavioural changes regarding healthy sanitation practices. While large-scale programs in India have increased latrine coverage, they have to some extent failed to bring behavioural changes ensuring optimal latrine use, including the safe disposal of child faeces, which is a significant source of exposure to faecal pathogens. Hence, this study was done to explore child faeces disposal practices in rural West Bengal and to elicit the determinants of unhygienic faeces disposal. Methods: Data collection was done using an interview method among the mothers of 502 under-5 children, following a pre-designed, semi-structured schedule during house-to-house visits in a set of villages in the Hooghly district of West Bengal. Results: The prevalence of unsafe disposal of child faeces was 72.4%, and maternal education, per capita income, and water source were found to be significantly associated with unsafe child faeces disposal. Conclusions: This study draws attention to the unsafe disposal of child faeces in this area of India and raises questions about the efficiency of sanitation campaigns in rural India that focus on expanding coverage rather than emphasizing behavioural changes, which are crucial to ensure the safe disposal of child faeces. Thus, it is urgently necessary to strengthen efforts focusing on behavioural changes regarding the safe disposal of child faeces in order to minimise adverse health outcomes.

      • Genetic Variation in MicroRNAs and Risk of Oral Squamous Cell Carcinoma in South Indian Population

        Sushma, PS,Jamil, Kaiser,Kumar, P Uday,Satyanarayana, U,Ramakrishna, M,Triveni, B Asian Pacific Journal of Cancer Prevention 2015 Asian Pacific journal of cancer prevention Vol.16 No.17

        Background: MicroRNAs (miRNAs) are small non-coding RNA molecules, implicated in several activities like initiation, progression and prognosis of various cancers. Single nucleotide polymorphisms (SNPs) in miRNA genes can lead to alteration in mRNA expression, resulting in diverse functional consequences. The aim of our study was to investigate the association of miR-149C>T and miR-196a2C>T SNPs with susceptibility to development of oral squamous cell carcinoma (OSCC) in South Indian subjects. Materials and Methods: 100 OSCC patients and 102 healthy controls from the general population were recruited for the study. Genetic analysis was performed by polymerase chain reaction/restriction fragment length polymorphism (PCR/RFLP) as per a standard protocol. Results: The genotype frequencies in miR-196a2 polymorphism, of TT, CT and CC in the OSCC patients were 69%,10% and 22% respectively while for control group it was 80%, 15% and 5% respectively. The CC genotype of miR196a2 polymorphism was significantly associated with oral squamous cell carcinoma. The genotype frequencies in miR-149 polymorphisms of CC, CT and TT in the oral squamous cell carcinoma (OSCC) patients were 72%, 22% and 6% respectively and for control group 88%, 12% and 0% respectively. CT and TT genotypes of miR149 polymorphism were found to be significantly associated with OSCC (p = 0.05 and 0.07). Conclusions: Our study suggests that miR-196a2C>T and miR-149C>T polymorphisms may play crucial roles in the development of OSCC in South Indian subjects.

      • A Review on Modified Image Enhancement Applications

        Mahendra PS Kuber,Manish Dixit 보안공학연구지원센터 2014 International Journal of Signal Processing, Image Vol.7 No.5

        The aim of image enhancement is to or to provide ‘better’ input for other improve the interpretability or perception of information in images for human viewing automated image processing techniques. Various Histogram Equalization techniques like CHE, GHE, BBHE, DSIHE, RMSHE and Multi-HE techniques are used for processing the image input to enhance its output. This paper provides a review over the modification of the brightness preserving dynamic histogram equalization technique to improve its brightness preserving and contrast enhancement abilities while reducing its computational complexity. There are many modified technique related to brightness preserving dynamic Histogram Equalization that uses statistics of digital images for their representation and processing are discussed here. Representation and processing of images in the spatial domain enables the technique to handle the inexactness of gray level values in a better way, resulting in improved performance. This algorithm enhances image contrast as well as preserves the brightness very effectively. Some images are not available to good quality, so these algorithms are used for image enhancement to improve the quality of the image.

      • KCI등재

        인간정자동결보존에 관한 연구

        구평삼(PS Ku) 대한산부인과학회 1985 Obstetrics & Gynecology Science Vol.28 No.2

        Contributions to research and clinical knowledge of frozen-stored human semen already has been presensed since 1964. The cryopreservation of the human semen requires a complete sperm analysis of the normal semen, full knowledge of cryoprotectant media and cryogenic methods. The following results were obtained by carefully observing the motility, survival rate, and viability of post-thawing sperms. 1. Of those 50 cases of semen collected for the experiment, the mean volume was 2.18ml, and sperm counting showed 60.9X106±83 per ml. The total count was 187.4 X106±29. The overall motility rate was 71.47±9.8%, and the normal sperms motility rate was 65±4%. For this study, the sperm motility was graded into five categories such as EXCELLANT(grade V), GOOD(grade IV), AVERAGE(grade III), FAIR(grade II), and POOR(grade I). 2. For the first trial, it has shown 14.37% of the survival rate for the cryopreserved sepcimen. However, for the second trial, the rate was 19%, 23.7% and 29.7% for each third and fourth trial, respectively. On the fifth trial, the rate was improved to 43.3% of survival rate. On the ninth trial, the survival rate was 61.4%. The overall survival rates were ranging from 55.7% to 85%, and 61.6% was accounted for the grade III or higher. 3. For the cryoprotectant media, Tris yolk, HSPM, and Lopata were employed in this study. The survival rate of sperms in each medium was 57.8% for Tris yolk, 50.8% for HSPM, and 75.7% for Lopata medium accordingly. 4. The fresh and cryopreserved semen has shown excellant motility and increased survival rates after washing with Hams F-10 medium. The survival rate of fresh semen was 88.5% after four hours, that was comparable with 79% for the cryopreserved semen. On the eighth hours of observation, the fresh and cryopreserved semens survival rates were 80% and 59%, respectively. On the sixteenth hours of observation, the survival rates for the fresh and cryopreserved semen were 56% and 33%, respectively. Finally, on the twenty-fourth hours, the survival rates for the fresh and cryopreserved semen were dropped down to 46.7% and 17%, respectively. By comparing the experimental of the fresh and cryopreserved semen, it has shown that the more drastic decrement of the survival rate for the cryopreserved semen was inevitable. 5. The aforementioned motility grade of the post-thawing sperms was different according with the each type of media. The post-thawing sperm motility was 33.3% in Tris yolk which their grades were higher than III. But the motility of the grade III or higher has increased by 98% after washing with Hams F-10 medium. Accordingly, the grade II in HSPM was 66.6%. But the grade was also improved to grade III after washing with it. Finally, the grade III in Lopata medium was 40% which was improved to 99% after washing with Hams F-10 medium. According to the above experimental data, the washing with Hams F-10 medium was very effective in improving the motility of the post-thawing sperms and also has shown effects that certain kind of media can make. 6. The motility rate of the semen observed thirty minutes after washing were 95% and 90% for the fresh and cryopreserved semen, respectively. However, these rates were decreased as time elapsed. Compare to 87% of fresh semens motility, the cryopreserved semens motility was 81% after two hours. On the eighth hours, the both fresh and cryopreserved semens motility rates were dropped to 67.7% and 54.4%, respectively. On the twelfth hours of observation, motility rates were kept decreasing for both fresh and cryopreserved semen by 54.5% and 47%, respectively. Finally, on the twenty-fourth hours of observation, only the fresh semen showed the motility rate of 46.4%.

      • KCI등재

        Unsafe Disposal of Child Faeces: A Community-based Study in a Rural Block in West Bengal, India

        Preeti PS,Sanjaya Kumar Sahoo,Dhiraj Biswas,Aparajita Dasgupta 대한예방의학회 2016 Journal of Preventive Medicine and Public Health Vol.49 No.5

        Objectives: A clean India is the responsibility of all Indians. One of the objectives of the Swachh Bharat Abhiyan (Clean India Initiative) is to bring about behavioural changes regarding healthy sanitation practices. While large-scale programs in India have increased latrine coverage, they have to some extent failed to bring behavioural changes ensuring optimal latrine use, including the safe disposal of child faeces, which is a significant source of exposure to faecal pathogens. Hence, this study was done to explore child faeces disposal practices in rural West Bengal and to elicit the determinants of unhygienic faeces disposal. Methods: Data collection was done using an interview method among the mothers of 502 under-5 children, following a pre-designed, semi-structured schedule during house-to-house visits in a set of villages in the Hooghly district of West Bengal. Results: The prevalence of unsafe disposal of child faeces was 72.4%, and maternal education, per capita income, and water source were found to be significantly associated with unsafe child faeces disposal. Conclusions: This study draws attention to the unsafe disposal of child faeces in this area of India and raises questions about the efficiency of sanitation campaigns in rural India that focus on expanding coverage rather than emphasizing behavioural changes, which are crucial to ensure the safe disposal of child faeces. Thus, it is urgently necessary to strengthen efforts focusing on behavioural changes regarding the safe disposal of child faeces in order to minimise adverse health outcomes.

      • Control of Shock Train in the Isolator of Hypersonic Engine

        Vignesh Ram PS,Tae Ho Kim(김태호),Heuy Dong Kim(김희동) 한국추진공학회 2019 한국추진공학회 학술대회논문집 Vol.2019 No.11

        The Isolator plays a critical role in scramjet engine situated between the inlet and the combustion chamber. The supersonic flow decelerated to subsonic speed achieved by compression waves. The flow filed is more complex with shock–shock interaction and shock boundary layer interaction. The series of shock wave occurs inside the isolator is called as shock train. In the present work the characteristic of shock train flow field in a constant area isolator and its control using suction is studied numerically. The results shows that the suction of boundary layer can influence the shock train length and with the optimum pressure ratio the shock train can become a single normal shock. The total pressure loss also improved by boundary layer suction.

      • KCI등재

        Quantitative histology-based classification system for assessment of the intestinal mucosal histological changes in patients with celiac disease

        Prasenjit Das,Gaurav PS Gahlot,Alka Singh,Vandana Baloda,Ramakant Rawat,Anil K Verma,Gaurav Khanna,Maitrayee Roy,Archana George,Ashok Singh,Aasma Nalwa,Prashant Ramteke,Rajni Yadav,Vineet Ahuja,Vishnu 대한장연구학회 2019 Intestinal Research Vol.17 No.3

        Background/Aims: The existing histological classifications for the interpretation of small intestinal biopsies are based on qualitative parameters with high intraobserver and interobserver variations. We have developed and propose a quantitative histological classification system for the assessment of intestinal mucosal biopsies. Methods: We performed a computer-assisted quantitative histological assessment of digital images of duodenal biopsies from 137 controls and 124 patients with celiac disease (CeD) (derivation cohort). From the receiver-operating curve analysis, followed by multivariate and logistic regression analyses, we identified parameters for differentiating control biopsies from those of the patients with CeD. We repeated the quantitative histological analysis in a validation cohort (105 controls and 120 patients with CeD). On the basis of the results, we propose a quantitative histological classification system. The new classification was compared with the existing histological classifications for interobserver and intraobserver agreements by a group of qualified pathologists. Results: Among the histological parameters, intraepithelial lymphocyte count of ≥25/100 epithelial cells, adjusted villous height fold change of ≤0.7, and crypt depth-to-villous height ratio of ≥0.5 showed good discriminative power between the mucosal biopsies from the patients with CeD and those from the controls, with 90.3% sensitivity, 93.5% specificity, and 96.2% area under the curve. Among the existing histological classifications, our quantitative histological classification showed the highest intraobserver (69.7%–85.03%) and interobserver (24.6%–71.5%) agreements. Conclusions: Quantitative assessment increases the reliability of the histological assessment of mucosal biopsies in patients with CeD. Such a classification system may be used for clinical trials in patients with CeD.

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