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      • Influencer Marketing: College Students’ Attitudes on Social Media

        Omar Dominguez,Mayra Hernandez,Thomas Lee,Joy Smith,Sua Jeon 전남대학교 생활과학연구소 2019 生活科學硏究 Vol.29 No.1

        Influencer marketing is a type of marketing in which respected experts are paid to advertise a product to influence follower attitudes. With the rise of social media use among college students, this study examines the effectiveness of influencer marketing in this market segment. Using data from 150 college students this study empirically examines the use of influencer marketing and the effect on college students’ consumer attitudes on social media. The results indicate that college students’ use of social media is positively associated with elevated consumer attitudes towards brands through influencer marketing. Discussion of these findings, their implications, and limitations are provided in the research.

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        Abnormal expression of H-Ras induces S-phase arrest and mitotic catastrophe in human T-lymphocyte leukemia

        Jorge Antonio Zamora Dominguez,Irma Olarte Carrillo,Rubén Ruiz Ramos,Christian Omar Ramos-Peñafiel,Luis Jiménez Zamudio,Ethel García Latorre,Federico Centeno Cruz,Adolfo Martínez Tovar 대한혈액학회 2023 Blood Research Vol.58 No.1

        Background Leukemia is a neoplasm with high incidence and mortality rates. Mitotic death has been observed in tumor cells treated with chemotherapeutic agents. Ras family proteins participate in the transduction of signals involved in different processes, such as proliferation, differentiation, survival, and paradoxically, initiation of cell death. Methods This study investigated the effect of H-Ras expression on human T-cell acute lymphoblastic leukemia MOLT-4 cells. Cells were electroporated with either wild-type (Raswt) or oncogenic mutant in codon 12 exon 1 (Rasmut) versions of H-Ras gene and stained for morphological analysis. Cell viability was assessed using trypan blue staining and cell cycle analysis using flow cytometry. H-Ras gene expression was determined using quantitative real-time reverse transcription polymerase chain reaction. The t, ANOVA, and Scheffe tests were used for statistical analysis. Results Human T-cell acute lymphoblastic leukemia MOLT-4 cells showed nuclear fragmentation and presence of multiple nuclei and micronuclei after transfection with either wt or mutant H-Ras genes. Cell cycle analysis revealed a statistically significant increase in cells in the S phase when transfected with either wt (83.67%, P <0.0005) or mutated (81.79%, P <0.0001) H-Ras genes. Although similar effects for both versions of H-Ras were found, cells transfected with the mutated version died at 120 h of mitotic catastrophe. Conclusion Transfection of human T-cell acute lymphoblastic leukemia MOLT-4 cells with either normal or mutated H-Ras genes induced alterations in morphology, arrest in the S phase, and death by mitotic catastrophe.

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