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RISS 인기검색어
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- 저자 : Nu Liu (검색결과 2 건)
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Yi-Jing Wang,Pan Zhao,Bing-Dong Sui,Nu Liu,Cheng-Hu Hu,Ji Chen,Chen-Xi Zheng,An-Qi Liu,Kun Xuan,Ya-Ping Pan,Yan Jin 생화학분자생물학회 2018 Experimental and molecular medicine Vol.50 No.-
Mesenchymal stem cell (MSC)-based regeneration, specifically cell aggregate or cell sheet engineering, is a promising approach for tissue reconstruction. Considering the advantages of ease of harvest and lack of immune rejection, the application of autologous MSCs (i.e., patients’ own MSCs) in regenerative medicine has developed considerable interest. However, the impaired cell viability and regenerative potential following MSCs impacted by disease remain a major challenge. Resveratrol (RSV) exhibits reliable and extensive rejuvenative activities that have received increasing clinical attention. Here, we uncovered that resveratrol enhances the functionality and improves the regeneration of mesenchymal stem cell aggregates. Periodontal ligament MSCs (PDLSCs) from normal control subjects (N-PDLSCs) and periodontitis patients (P-PDLSCs) were investigated. Compared to N-PDLSCs, P-PDLSCs were less capable of forming cell aggregates, and P-PDLSC aggregates showed impaired osteogenesis and regeneration. These functional declines could be mimicked in N-PDLSCs by tumor necrosis factor alpha (TNF-α) treatment. Notably, a TNF-α-induced functional decline in N-PDLSC aggregates was rescued by RSV application. More importantly, in both N-PDLSCs and P-PDLSCs, RSV promoted cell aggregate formation and improved their osteogenic potential. Furthermore, as proven ectopically in vivo, the tissue regenerative capability of P-PDLSC aggregates was also enhanced after RSV treatment during aggregate formation in vitro. Finally, in a rat in situ regeneration model, we successfully applied both N-PDLSC aggregates and P-PDLSC aggregates to repair periodontal defects upon long-term functional improvements by RSV preconditioning. Together, our data unravel a novel methodology for using pharmacology (i.e., RSV)-based cell aggregate engineering to improve the functionality and facilitate the regeneration of MSCs from both healthy and inflammatory microenvironments, shedding light on improving the application of autologous MSC-mediated regenerative medicine.
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축구선수들의 경기력 향상을 위한 트레이닝 방법 문헌고찰
이서민 ( Rui-min Li ),조영현 ( Yeong-hyun Cho ),유주인 ( Joo-in Yu ),유붕 ( Peng Liu ),사공혁 ( Hyuk Sakong ),박영준 ( Young-jun Park ),한누리 ( Nu-ri Han ),서태범 ( Tae-beom Seo ) 제주대학교 해양스포츠센터 2020 해양스포츠연구 Vol.10 No.2
본 연구의 목적은 축구선수의 경기력 향상을 위한 트레이닝 방법을 확인하고자 하는데 있다. 이를 위해 온라인(Online) 상에서 Pubmed, Riss, Kiss, Google scholar에서 2000~2020년 사이의 기간을 설정하고, 용어는 Training, Performance, soccer player, core training 그리고 Plyometric training을 사용하여 문헌 조사를 실시하였다. 축구선수의 경기력관련 체력요인 향상을 위한 훈련 프로그램의 효과를 보고한 20개의 논문을 선정하였고, 플라이오메트릭과 코어트레이닝 각각 5개씩 10개의 논문이 최종 채택되었다. 채택한 문헌을 기반으로 내용을 정리한 결과 플라이오메트릭과 코어트레이닝은 근력, 근지구력, 민첩성, 순발력, 허리와 무릎 등속성 근기능 및 유연성을 증가시키는 것으로 확인되었다. 따라서 플라이오메트릭과 코어트레이닝의 적용은 축구선수의 경기력 관련 체력을 향상시킨다는 중요한 정보를 제공한다. The purpose of this study is to identify a training method for improving soccer player's performance. To this end, the period between 2000 and 2020 was set in Pubmed, Riss, Kiss, and Google scholar on Online, and a literature survey was conducted using the terms Training, Performance, soccer player, core training and Plyometric training. Twenty academic journals were selected to report the effectiveness of training programs to improve the fitness factors related to the performance of soccer players, and ten papers were finally selected, five each for plyometric and core training. As a result of organizing the contents based on the adopted literature, it was confirmed that plyometric and core training increased muscle strength, muscular endurance, agility, power, waist and knee isokinetic muscle function and flexibility. Therefore, these results provide information that plyometric and core training may improve physical fitness related to the performance of soccer players.
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