Advancing LHC probes of dark matter from the inert two-Higgs-doublet model with the monojet signal

Belyaev, A.,Moretti, S.,Fernandez Perez Tomei, T. R.,Novaes, S. F.,Mercadante, P. G.,Moon, C. S.,Panizzi, L.,Rojas, F.,Thomas, M. American Physical Society 2019 Physical review. D Vol.99 No.1

Effects of the Use of Curcumin on Ulcerative Colitis and Crohn's Disease: A Systematic Review

Ricardo de Alvares Goulart,Sandra M. Barbalho,Vinícius Marinho Lima,Gabriela Achete de Souza,Julia Novaes Matias,Adriano Cressoni Araújo,Cláudio José Rubira,Rogério Leone Buchaim,Daniela Vieira Buchai 한국식품영양과학회 2021 Journal of medicinal food Vol.24 No.7

Inflammatory bowel disease (IBD) is an umbrella term used to describe chronic inflammatory disorders related to a substantial reduction in the quality of life of patients. Some patients with Crohn's disease (CD) and ulcerative colitis (UC) are refractory to conventional therapies, and Curcuma longa derivatives have been considered as adjuvants. Owing to the anti-inflammatory and antioxidant effects, some clinical trials used this plant in the therapeutic approach of IBD, and some meta-analyses evaluated the outcomes found in these studies. Owing to controversial findings, our systematic review aimed to evaluate these studies to show whether C. longa compounds can still be considered in the therapeutic approach of patients with CD and UC. MEDLINE-PubMed, EMBASE, and Cochrane were searched, and Preferred Reporting Items for a Systematic Review and Meta-Analysis guidelines were followed. The results of the randomized clinical trials (RCTs) showed promising results with the use of curcumin in the therapeutic approach of both UC and CD patients. Some meta-analyses show controversial results, possibly due to the presence of bias in the included studies. The actions of curcumin are achieved by several mechanisms, such as reducing the expression of interleukin (IL)-1, IL-6, IL-12, and tumor necrosis factor-α. Moreover, it reduces the levels of reactive oxygen species, such as superoxide anions and malondialdehyde. The results of using curcumin in CD and UC patients are challenging to be evaluated because RCTs are variable in the dose and the formulations of curcumin, in the time of treatment, and the route of administration. The number of patients in the samples is also usually small.

An introductory review on the application of principal component analysis in the data exploration of the chemical analysis of food samples

Anderson Santos Souza,Marcos Almeida Bezerra,Uillian Mozart Ferreira Mata Cerqueira,Caiene Jesus Oliveira Rodrigues,Bianca Cotrim Santos,Cleber Galvão Novaes,Erica Raina Venâncio Almeida 한국식품과학회 2024 Food Science and Biotechnology Vol.33 No.6

Principal component analysis (PCA) is currently one of the most used multivariate data analysis techniques for evaluating information from food analysis. In this review, a brief introduction to the theoretical principles that underlie PCA will be given, in addition to presenting the most commonly used computer programs. An example from the literature was discussed to illustrate the use of this chemometric tool and interpretation of graphs and parameters obtained. A list of recently published articles will also be presented, in order to show the applicability and potential of the technique in the food analysis field.

Evaluation of microbiological, cellular and risk factors associated with subclinical mastitis in female buffaloes

de Oliveira Moura, Emmanuella,do Nascimento Rangel, Adriano Henrique,de Melo, Maria Celeste Nunes,Borba, Luiz Henrique Fernandes,de Lima, Dorgival Morais Junior,Novaes, Luciano Patto,Urbano, Stela Ant Asian Australasian Association of Animal Productio 2017 Animal Bioscience Vol.30 No.9

Objective: This study aimed to evaluate the microbiological and cellular milk profile for the diagnosis of subclinical mastitis in female buffaloes and to assess risk factors for predisposition of the disease. Methods: Analyses were carried out by standard plate count (SPC), identification of species and antibiotic resistance, somatic cell count (SCC), electrical electrical conductivity of milk (ECM), and lactoferrin content in milk. Teat cups were swabbed to evaluate risk factors, observing hyperkeratosis, milking vacuum pressure and cleanliness of the site. Hence, 30 female buffaloes were randomly selected (15 from a group in early lactation and 15 in late lactation). Results: The most common bacteria in the microbiological examination were Staphylococcus spp., Streptococcus spp. and Corynebacterium sp. In the antibiotic sensitivity test, 10 (58.82%) of the 17 antibiotics tested were sensitive to all isolates, and resistant bacteria were Streptococcus uberis, Streptococcus dysgalactiae, Streptococcus haemolyticus, and Escherichia coli. It was observed that positive samples in the microbiological examination showed total bacterial count between $9.10{\times}10^3$ to $6.94{\times}10^6$ colony forming units/mL, SCC between 42,000 to 4,320,000 cells/mL and ECM ranging from 1.85 to 7.40 mS/cm. It was also found that the teat cups had high microbial counts indicating poor hygiene, and even faults in the cleanliness of the animals' waiting room were observed. It is concluded that values of SCC above 537,000 cells/mL and ECM above 3.0 mS/mL are indications of mammary gland infection for this herd; however, the association of these values with a microbiological analysis is necessary to more accurately evaluate the health status of mammary glands with subclinical mastitis. Conclusion: Through phenotypic characterization of bacteria involved in the samples, the genera Staphylococcus spp., Streptococcus spp., and Corynebacterimum bovis were the most prevalent in this study. Faults in environment and equipment hygienization are factors that are directly associated with mastitis.

Preliminary study of AR navigation-guided core-needle breast biopsy

Nova Eka Diana,Jegyeong Ryu,Hee Ryung Lee,Youngseok O,Deukhee Lee 제어로봇시스템학회 2022 제어로봇시스템학회 국제학술대회 논문집 Vol.2022 No.11

Accurate tumor localization has remained to be one of the biggest challenges in core-needle biopsy due to the malleability and texture-heterogeneity of tissues surrounding a tumor. To overcome these limitations, we explored the effectiveness of augmented reality (AR)-guidance to navigate the core-needle insertion in breast biopsy thanks to the enhanced technology of AR. Our proposed framework consists of two independent functions: tumor localization and needle pose tracking in real-time. First, tumor localization was achieved by employing the two-front environmental sensors of HoloLens 2 (HL2) for tracking the passive-reflective markers. Given the geometrical information of the reference markers, the stereo-correspondences and the marker pose can be calculated efficiently for overlaying the corresponding virtual models in HL2. Second, an external RGB camera was used to track the pose of a needle. A You-Only-Look-Once (YOLO) model with a customized training set of 200 images was employed to detect the collinear pinkt-ape points attached to the needle. The interpoint-distance between these points will be utilized to estimate the pose of a needle that will be sent to HL2 using TCP/IP communication. Finally, real-time navigation of needle insertion can be rendered in HL2 using a more accurate transformation to assist the breast biopsy. Overall, the preliminary results demonstrate that the whole process can be executed in a reasonable running time of less than two seconds.

The Influence Factors on Customer Satisfaction and Loyalty in Distribution: An Empirical Study on Sushi Tei Restaurant, Jakarta

Nova ANDRIYANI,Z. HIDAYAT 한국유통과학회 2021 유통과학연구 Vol.19 No.6

Purpose: A restaurant is a business of the physical distribution of food and beverages which includes intercultural interaction. This research paper aims to examine the influence of Japanese taste as a product advantage, determining service quality factor in the restaurant business, the e-CRM that involves technology, social media campaigns to reach the target market of young people, and customer satisfaction on customer loyalty in Sushi Tei restaurant. This study also intends to find direct and indirect influence between the variables. Research design, data and methodology: Quantitative research was conducted using a survey method by distributing 100 questionnaires to Sushi Tei customers in Jakarta, consisting of Gen Z and Millennials. Samples were taken at each outlet in the Jakarta area on weekend and weekdays by purposive sampling. Data was generated by path analysis Results: The results showed that Japanese taste, service quality, and e-CRM significantly influence customer satisfaction and customer loyalty. However, social media campaigns failed to influence customer loyalty. As a result, customer satisfaction has a significant influence on customer loyalty within Sushi Tei restaurant. Conclusion: The study also proposed significant implications to develop and maintain a relationship with the customer to gain satisfaction and loyalty in the food and beverage industry.

Beneficial Effects of a Synbiotic Supplement on Self-Perceived Gastrointestinal Well-Being and Immunoinflammatory Status of Healthy Adults

Esther Nova,Blanca Viadel,Julia Wärnberg,Jose E. Carreres,Ascensión Marcos 한국식품영양과학회 2011 Journal of medicinal food Vol.14 No.1

The use of synbiotics as health promoters is still poorly defined, and human intervention studies are scarce. This study was designed to evaluate the effects of a commercialized synbiotic product containing Lactobacillus acidophilus La5, Bifidobacterium animalis ssp. lactis Bb-12, Lactobacillus delbrueckii ssp. bulgaricus, Lactobacillus paracasei ssp. paracasei, Streptococcus thermophilus, and fructooligosaccharides on the self-reported gastrointestinal well-being and the immunoinflammatory status of healthy human subjects. In this randomized, double-blind, placebo-controlled study, 20 women and 16 men (25–45 years old) received either three tablets per day of the synbiotic product (2.4×109 colony-forming units/day) or placebo during 6 weeks. Gastrointestinal symptoms and bowel habits were evaluated through a self-administered questionnaire. In those subjects suffering from any kind of digestive disturbance (mild dyspepsia, flatulence, postprandial bloating, constipation, etc.), improvements in symptoms after product consumption were also evaluated. Blood lymphocyte subsets, phagocytic activity, serum C-reactive protein, ceruloplasmin, and adhesion molecules concentrations were analyzed prior and after treatment. A significant improvement in overall self-reported gastrointestinal symptoms and bowel habit was found in the synbiotic group. A marginal effect of treatment (analysis of variance P=.050) was observed with L-selectin, which showed a significant decrease in the synbiotic group (P=.019). In addition, basal L-selectin levels correlated with final intercellular adhesion molecule (ICAM)-1 levels (r=0.468; P=.050), and basal ICAM-1 levels tended to correlate negatively with final L-selectin concentration (r=–0.457; P=.056). None of these correlations was found in the placebo group. The rest of the immunological parameters studied were not modified by the intervention. In conclusion, consumption of the synbiotic product improves self-perceived bowel habits and might facilitate a better profile of adhesion molecules in healthy adults.

The Burden Experience of Family Caregiver of Older Adults with Chronic Illness

Yustisia Nova,Titin Aprilatutini,Tuti Anggriani Utama,Mahmasoni Masdar 한국지역사회간호학회 2023 지역사회간호학회지 Vol.34 No.2

Purpose: This study aims to find out further about the burden on families in undertaking caregiving for the elderly with chronic illnesses. Methods: A qualitative study was developed using in-depth interviews with 12 family caregivers selected by purposive sampling in July 2022. The thematic analysis was then carried out using the Colaizzi method, and N-Vivo 12 Qualitative Data Analysis Software was used to assist with the content analysis. Results: The result from the experience interview analysis of caregivers participating in this study were 54 codes which were categorized into thirteen categories. Then, they were derived into four themes, as follows: 1) Physical burden of the caregivers for the elderly with chronic illness, 2) Psychological burden of the caregivers for the elderly with chronic illness, 3) Obstacle of caregivers for the elderly with chronic illness, 4) The state of caregivers who perform caregiving for the elderly with chronic illness. Conclusion: The experience of caregivers in undertaking caregiving for the elderly with chronic disease has many obstacles, such as physical, psychological, and economic burdens. Caregivers often find positive aspects of their experiences while caregiving for the elderly, although their burden also constantly increases. Health facilities should pay serious attention to family caregivers and facilitate programs that can help reduce the burden on family caregivers.

A Contemporary History of North Korea

Daniel Schwekendiek,Nova Mercier 숙명여자대학교 아시아여성연구원 2016 Asian Women Vol.32 No.4

The breakdown of the public distribution system in North Korea and the famine of the 1990s made way for citizen-led grassroots marketization as a means of survival. A confluence of several factors including the skewed ratio of males in official jobs, the state-sanctioned role of women as housewives and mothers, mandatory military service for males and the predominance of females in the light industry and service sectors allowed women greater opportunity to participate in this burgeoning market economy. An understudied aspect of this new phenomenon is if regional discrepancies in North Korea affect the role of women in the markets. While large regional socioeconomic differences do exist in North Korea, previous studies only used haphazard samples of refugees who were coming primarily from the Northeastern province close to China. Through semi-structured, open-ended oral history interviews with five female refugees coming from different regions of North Korea, this study paid special attention to women who witnessed changes in several provinces, including the capital. The findings here are that while some disparities certainly exist across regions, the urban/rural gap is more pronounced. This study also confirmed that despite being “double victims” of both state marginalization and social discrimination, North Korean women are now the primary breadwinners for the nuclear family―challenging the traditional gender roles as a result of this nationwide market participation.

The Environmental Impact of Tall vs Small: A Comparative Study

Drew, Christopher,Nova, Katrina Fernandez,Fanning, Keara Council on Tall Building and Urban Habitat Korea 2015 International journal of high-rise buildings Vol.4 No.2

The concept of vertical living has been hailed as a solution to control fast growth and urbanization of cities worldwide. As super tall residential projects become more common and sustainability considerations become more necessary, their efficiency has been called into question. How do vertical residential developments compare with suburban homes? What are the environmental advantages and disadvantages of vertical communities? Is there a middle ground? We present the results from an AS+GG study that compares the environmental performance of different housing typologies ranging from a 215 supertall building to single family residences, including several scales in between. Our samples comprise 2,000 residential units per type and include the infrastructure needed to support them. We analyzed land use, energy use, and lifecycle carbon emissions for each typology. The results show that different typologies perform better depending on the parameter being assessed. We discuss these findings; assess overall performance, and present conclusions.