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      • The Theoretical Grounds of the Advertisement Comment

        Fang Ning 한국유통과학회 2013 한국유통과학회 학술대회 논문집 Vol.2013 No.-

        The paper is not a standard thesis with a central argument but a discussion of the theoretical grounds about the given advertisement comment. It will mainly analyze structuralism, Marxism, feminism, traditionalism, discourse transfer and some other aspects related to both linguistics and literary criticism, which should be, in my opinion, the theoretical background for the argumentation in the article in question.

      • SCOPUSSCIEKCI등재

        Camouflage treatment in adult skeletal Class III cases by extraction of two lower premolars

        Ning, Fang,Duan, Yinzhong The Korean Association Of Orthodontists 2010 대한치과교정학회지 Vol.40 No.5

        Objective: The purpose of this study was to evaluate the dentoskeletal and soft tissue profile changes after extraction of two lower first or second premolars in "borderline" adult skeletal Class III cases. Methods: Twenty-eight patients with "borderline" skeletal Class III malocclusion were studied. All of them were treated by extraction of two lower first or second premolars. Lateral cephalometric radiographs taken at the start and end of treatment were analysed. Twenty-five cephalometric variables were calculated and paired $t$-tests were performed. Results: After treatment, no significant changes were noted in the skeletal parameters ($p{\geq}0.05$). Regarding the dental parameters, the L1-MP angle decreased by $8.1^{\circ}$, the U1-L1 angle increased by $7.7^{\circ}$ ($p$ < 0.01), the overjet distance increased by 5.7 mm ($p$ < 0.01), the L1-NB angle decreased by $7.3^{\circ}$ and the L1-NB distance decreased by 4.8 mm ($p$ < 0.01). The soft tissue parameters of Li-E, Li-H and Li-RL2 distance decreased by 3.2 mm, 3.4 mm and 4.1 mm respectively ($p$ < 0.01). Conclusions: Orthodontic camouflage treatment by extraction of two lower first or second premolars provides a viable treatment alternative for "borderline" skeletal Class III cases to achieve a good occlusal relationship. 이번 연구의 목적은 성인 골격성 III급 부정교합환자의 하악 제1소구치 또는 제2소구치 발치 후에 치조골격성 변화와 연조직 변화를 평가하는 데 있다. 28명의 경계선상에 있는 골격성 III급 부정교합환자들이 연구되었다. 모든 환자는 하악 제1소구치 또는 제2소구치를 발치한 후 치료되었으며 치료 전과 치료 후 측모두부방사선사진을 촬영하여 paired t-test를 통해 분석하였다. 치료 후에 골격적으로 유의성 있는 변화는 관찰되지 않았다. 치성변화에 대해 하악 전치각도가 8.1도 정도 감소하였으며 interincisal angle은 7.7도 정도 증가하였다 ($p$ < 0.01). 수평 피개는 5.7 mm로 증가하였으며 ($p$ < 0.01), L1-NB 각은 7.3도 감소하였고 L1-NB 거리는 4.8 mm 감소하였다 ($p$ < 0.01). 연조직 변화에 있어 Li-E, Li-H과 LiRL2 거리는 각각 3.2 mm, 3.4 mm, 4.1 mm 감소하였다 ($p$ < 0.01). 심하지 않은 골격성 III급 부정교합 환자에 대한 하악 소구치 발치를 통한 교정적인 보상치료는 우수한 교합관계를 달성할 수 있으며 예측이 가능한 치료 대안이 될 수 있다.

      • KCI등재

        Camouflage treatment in adult skeletal Class III cases by extraction of two lower premolars

        Fang Ning,Yinzhong Duan 대한치과교정학회 2010 대한치과교정학회지 Vol.40 No.5

        이번 연구의 목적은 성인 골격성 III급 부정교합환자의 하악 제1소구치 또는 제2소구치 발치 후에 치조골격성 변화와 연조직 변화를 평가하는 데 있다. 28명의 경계선상에 있는 골격성 III급 부정교합환자들이 연구되었다. 모든 환자는 하악 제1소구치 또는 제2소구치를 발치한 후 치료되었으며 치료 전과 치료 후 측모두부방사선사진을 촬영하여 paired t-test를 통해 분석하였다. 치료 후에 골격적으로 유의성 있는 변화는 관찰되지 않았다. 치성변화에 대해 하악 전치각도가 8.1도 정도 감소하였으며 interincisal angle은 7.7도 정도 증가하였다 (p < 0.01). 수평 피개는 5.7 mm로 증가하였으며 (p < 0.01), L1-NB 각은 7.3도 감소하였고 L1-NB 거리는 4.8 mm 감소하였다 (p < 0.01). 연조직 변화에 있어 Li-E, Li-H과 LiRL2 거리는 각각 3.2 mm, 3.4 mm, 4.1 mm 감소하였다 (p < 0.01). 심하지 않은 골격성 III급 부정교합 환자에 대한 하악 소구치 발치를 통한 교정적인 보상치료는 우수한 교합관계를 달성할 수 있으며 예측이 가능한 치료 대안이 될 수 있다. Objective: The purpose of this study was to evaluate the dentoskeletal and soft tissue profile changes after extraction of two lower first or second premolars in “borderline” adult skeletal Class III cases. Methods: Twenty-eight patients with “borderline” skeletal Class III malocclusion were studied. All of them were treated by extraction of two lower first or second premolars. Lateral cephalometric radiographs taken at the start and end of treatment were analysed. Twenty-five cephalometric variables were calculated and paired t-tests were performed. Results: After treatment, no significant changes were noted in the skeletal parameters (p ≥ 0.05). Regarding the dental parameters, the L1-MP angle decreased by 8.1˚, the U1-L1 angle increased by 7.7˚ (p < 0.01), the overjet distance increased by 5.7 mm (p < 0.01), the L1-NB angle decreased by 7.3˚ and the L1-NB distance decreased by 4.8 mm (p < 0.01). The soft tissue parameters of Li-E, Li-H and Li-RL2 distance decreased by 3.2 mm, 3.4 mm and 4.1 mm respectively (p < 0.01). Conclusions: Orthodontic camouflage treatment by extraction of two lower first or second premolars provides a viable treatment alternative for “borderline” skeletal Class III cases to achieve a good occlusal relationship. (Korean J Orthod 2010;40(5):349-357)

      • KCI등재

        Two Androstane Derivatives from the Cultures of Fungus Marasmiellus ramealis (Bull.) Singer

        Ning-Ning Yang,Qing-Yun Ma,Sheng-Zhuo Huang,Hao-Fu Dai,Zhi-Kai Guo,Zhi-Fang Yu,You-Xing Zhao 대한화학회 2014 Bulletin of the Korean Chemical Society Vol.35 No.11

        A new androstane derivative, 4β-methyl-15-oxa-14β-androstane-7-ene-4α-carboxylic acid (1) and a known one 4β-methyl-15-oxa-14β-androstane-7-ene-4α-hydroxyl (2) were isolated from the EtOAc extract of the cultures of the fungus Marasmiellus ramealis (Bull.) Singer. Their structures were elucidated on the basis of 1D and 2D NMR as well as MS spectroscopic data analysis. The inhibitory activity of two isolates against acetylcholinesterase (AChE) revealed that compound 1 exhibited definitely inhibitory activity.

      • KCI등재
      • SCOPUSKCI등재

        Two Androstane Derivatives from the Cultures of Fungus Marasmiellus ramealis (Bull.) Singer

        Yang, Ning-Ning,Ma, Qing-Yun,Huang, Sheng-Zhuo,Dai, Hao-Fu,Guo, Zhi-Kai,Yu, Zhi-Fang,Zhao, You-Xing Korean Chemical Society 2014 Bulletin of the Korean Chemical Society Vol.35 No.11

        A new androstane derivative, $4{\beta}$-methyl-15-oxa-$14{\beta}$-androstane-7-ene-$4{\alpha}$-carboxylic acid (1) and a known one $4{\beta}$-methyl-15-oxa-$14{\beta}$-androstane-7-ene-$4{\alpha}$-hydroxyl (2) were isolated from the EtOAc extract of the cultures of the fungus Marasmiellus ramealis (Bull.) Singer. Their structures were elucidated on the basis of 1D and 2D NMR as well as MS spectroscopic data analysis. The inhibitory activity of two isolates against acetylcholinesterase (AChE) revealed that compound 1 exhibited definitely inhibitory activity.

      • Quality of Life of Male Spouse Caregivers for Breast Cancer Patients in China

        Zhu, Ping,Fu, Ju-Fang,Wang, Bo,Lin, Jing,Wang, Yan,Fang, Ning-Ning,Wang, Dan-Dan Asian Pacific Journal of Cancer Prevention 2014 Asian Pacific journal of cancer prevention Vol.15 No.10

        Background: The aim of this study was to describe the characteristics of male spouse caregivers of breast cancer patients in China, assess their quality of life (QOL), and investigate the influencing factors. Materials and Methods: A total of 243 breast cancer patient-spouse caregiver dyads were recruited from four hospitals in Shanxi and Anhui province of China. A cross-sectional design was applied to collect data and the Chinese version of the Medical Outcomes Study 36-item Short Form (SF-36) was used to measure caregivers' QOL, and the Chinese version of M.D. Anderson Symptom Inventory (MDASI-C) was applied to measure patient symptom severity and interference. Pearson's correlation was used to examine the correlations between caregiver burden and QOL. The multiple regression analysis was used to determine the most predictive factors influencing QOL. Results: The scores of all SF-36 scales were above 50.0, which were much lower than that of general mainland Chinese males. Mental QOL was significantly worse than physical QOL. Spouses demographic characteristics, caregiving-related variables and patient symptoms were related to spouse QOL. Caregiver burden has a negative relationship with QOL. Conclusions: A decrease in life events and patient symptoms, as well as increase in spouse sleeping time and family income, ought to improve QOL.

      • KCI등재

        Preclinical Study of Cell Therapy for Osteonecrosis of the Femoral Head with Allogenic Peripheral Blood-Derived Mesenchymal Stem Cells

        Tao Zhang,Qiang Fu,Ning-Ning Tang,Qian Zhang,Yi Liu,Jia-Chen Peng,Ning Fang,Li-Mei Yu,Jin-Wei Liu 연세대학교의과대학 2016 Yonsei medical journal Vol.57 No.4

        Purpose: To explore the value of transplanting peripheral blood-derived mesenchymal stem cells from allogenic rabbits (rPBMSCs)to treat osteonecrosis of the femoral head (ONFH). Materials and Methods: rPBMSCs were separated/cultured from peripheral blood after granulocyte colony-stimulating factor mobilization. Afterwards, mobilized rPBMSCs from a second passage labeled with PKH26 were transplanted into rabbit ONFH models, which were established by liquid nitrogen freezing, to observe the effect of rPBMSCs on ONFH repair. Then, the mRNA expressions of BMP-2 and PPAR-γ in the femoral head were assessed by RT-PCR. Results: After mobilization, the cultured rPBMSCs expressed mesenchymal markers of CD90, CD44, CD29, and CD105, but failed to express CD45, CD14, and CD34. The colony forming efficiency of mobilized rPBMSCs ranged from 2.8 to 10.8 per million peripheralmononuclear cells. After local transplantation, survival of the engrafted cells reached at least 8 weeks. Therein, BMP-2 was up-regulated, while PPAR-γ mRNA was down-regulated. Additionally, bone density and bone trabeculae tended to increase gradually. Conclusion: We confirmed that local transplantation of rPBMSCs benefits ONFH treatment and that the beneficial effects are relatedto the up-regulation of BMP-2 expression and the down-regulation of PPAR-γ expression.

      • KCI등재

        위안화 환율 변화의 중국 수출입에 대한 영향 분석

        필위녕(Bi, Wei Ning),임방방(Ren, Fang Fang),남수중(Nam, Soo Joong) 영남대학교 중국연구센터 2014 중국과 중국학 Vol.22 No.-

        본 논문은 요한슨 공적분 검정법과 중력모형을 이용하여 위안화 환율변화가 중국 용도별 수출입에 미친 영향을 실증적으로 분석하였다. 1998년부터 2012년까지 중국과 20개 교역대상국의 연도별 패널데이터를 고정효과, 확률효과와 최소자승법(OLS)으로 나누어 분석하였다. 본 논문의 주요 결과는 다음과 같은 의미를 갖는다. 첫째, 환율의 변화와 수출입 사이에는 장기적 균형관계가 존재하는 것으로 나타났다. 환율의 수출 및 수입 수요 탄력성의 절대값 합이 3.09에 달해 1보다 크다는 것을 알 수 있었다. 즉 마샬-러너 조건이 충족되었다. 본 연구는 위안화의 명목환율 변화가 장기적으로 중국 수출입에 영향을 미칠 수 있음을 규명하였다. 위안화 환율변화가 중국의 수출입에 미치는 영향을 추정한 결과에 따르면 수출보다는 수입이 환율변동에 대해 더 민감하게 반응하는 것을 알 수 있었다. 둘째, 중국과 외국의 GDP 변화가 수출입에 미친 영향을 보면, 중국의 수출에 대한 외국의 GDP 영향, 즉 외국의 수입 수요는 모두 통계적으로 1%에서 유의미하였으나, 중간재와 소비재보다 자본재의 수출에 대한 영향이 가장 컸던 것으로 파악되었다. 또한 수입의 경우, 중국 국내수입 수요, 즉 GDP 증가는 자본재, 중간재, 소비재 모두 회귀계수 값이 높지 않은 반면, 중간재와 소비재의 경우 통계적으로 1%에서 유의하였다. 셋째, 실증분석 결과는 실질실효 환율이 절상된다면 자본재, 중간재, 소비재 수출이 모두 증가하는 것으로 나타났다. 모두 통계적으로도 유의하였다. 반면 수입의 경우, 환율 변화의 영향이 제한적인 것으로 추정되었다. 특히 자본재의 수입이 통계적으로 유의미한 값을 제시하지 못하였다. This paper focuses on the long-term and short-term impact of RMB exchange rate on China’s export and import trade to 20 countries from 1980 to 2012. Through the Johansen cointegration test and gravity model, this paper concludes that the export is a positive to the change of exchange rate in the long-term, but the import is negative. The exchange rate elasticity of the import is larger than the export. As a result, Marshall-Lerner condition is valid. It is 3.09, more high than 1. Therefore, the GDP of China and foreign countries are the important factors and possesses a significantly positive impact on China’s exports and imports. The empirical model reveals that the effects of RMB real effective exchange rate are a significantly positive on capital goods, intermediate goods and consumption goods exports. But China’s imports have not any significant results statistically, particularly on capital goods imports. From the empirical result, it is proved that exchange rate flexibility has the obvious influence on China’s export and import trade in the short and long term.

      • Long Non-coding RNAs are Differentially Expressed in Hepatocellular Carcinoma Cell Lines with Differing Metastatic Potential

        Fang, Ting-Ting,Sun, Xiao-Jing,Chen, Jie,Zhao, Yan,Sun, Rui-Xia,Ren, Ning,Liu, Bin-Bin Asian Pacific Journal of Cancer Prevention 2014 Asian Pacific journal of cancer prevention Vol.15 No.23

        Background: Metastasis is a major reason for poor prognosis in patients with cancer, including hepatocellular carcinoma (HCC). A salient feature is the ability of cancer cells to colonize different organs. Long non-coding RNAs (lncRNAs) play important roles in numerous cellular processes, including metastasis. Materials and Methods: In this study, the lncRNA expression profiles of two HCC cell lines, one with high potential for metastasis to the lung (HCCLM3) and the other to lymph nodes (HCCLYM-H2) were assessed using the Arraystar Human LncRNA Array v2.0, which contains 33,045 lncRNAs and 30,215 mRNAs. Coding-non-coding gene co-expression (CNC) networks were constructed and gene set enrichment analysis (GSEA) was performed to identify lncRNAs with potential functions in organ-specific metastasis. Levels of two representative lncRNAs and one representative mRNA, RP5-1014O16.1, lincRNA-TSPAN8 and TSPAN8, were further detected in HCC cell lines with differing metastasis potential by qRT-PCR. Results: Using microarray data, we identified 1,482 lncRNAs and 1,629 mRNAs that were differentially expressed (${\geq}1.5$ fold-change) between the two HCC cell lines. The most upregulated lncRNAs in H2 were RP11-672F9.1, RP5-1014O16.1, and RP11-501G6.1, while the most downregulated ones were lincRNA-TSPAN8, lincRNA-CALCA, C14orf132, NCRNA00173, and CR613944. The most upregulated mRNAs in H2 were C15orf48, PSG2, and PSG8, while the most downregulated ones were CALCB, CD81, CD24, TSPAN8, and SOST. Among them, lincRNA-TSPAN8 and TSPAN8 were found highly expressed in high lung metastatic potential HCC cells, while lowly expressed in no or low lung metastatic potential HCC cells. RP5-1014O16.1 was highly expressed in high lymphatic metastatic potential HCC cell lines, while lowly expressed in no lymphatic metastatic potential HCC cell lines. Conclusions: We provide the first detailed description of lncRNA expression profiles related to organ-specific metastasis in HCC. We demonstrated that a large number of lncRNAs may play important roles in driving HCC cells to metastasize to different sites; these lncRNAs may provide novel molecular biomarkers and offer a new basis for combating metastasis in HCC cases.

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