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崔七男,朴聖珪,丁梧鎭,문경국 조선대학교 기초과학연구소 1984 自然科學硏究 Vol.7 No.1
pH 6.0∼12.0 範圍에서 0.15M 타르타르 酸鹽支持溶液 속에서 Cd(Ⅱ) Polarogram을 25℃에서 二段還元波를 調査한 결과 pH8.2部分 까지는 限界電流 및 半波電位값이 一定하며 한편 같은 濃度의 窒酸鹽 支持溶液을 사용하였을 때에 比하여 一段還元波의 半波電位값은 0.03volt 陰의 電位값으로 移動하고, 限界電流 값은 21% 減少되었다. pH8.2 部分 以上부터 限界電流 값이 急激하게 增加하다가 pH8.9 以上부터는 다시 急激하게 減少하는 現象을 보여 주었다. 한편 pH8.2 以上부터는 半波電位가 pH11.0에서는 -1.37volt로 되었다. 可能한 電極反應을 假定하여, pH11.0에 이르기까지의 還元波移動의 原因을 檢討하였다. The second reduction waves of the polarogram of Cd(Ⅱ) in 0.15M sodium tartrate solution were investigated in the range of pH from 6.0 to 12.0 at 25 C. Up to pH 8.2, the limiting current and the half wave potential were found to be constant, and when compared with the nitrate solution equal to the concentration of sodium tartrate, the limiting current of the first reduction wave has been decrease 21% and the half wave potential of the first reduction wave shifted by -0.03 volt. The values of limiting current were sharply increased above pH 8.2, and maximum value was obtained at pH 9.8. The half wave potentials were gradually proceeded in negative direction with increasing pH and the half wave potential of -1.37 volt was obtained at the pH 11.0. Suggesting possible mechanisms of electrode reactions, the anomalous behavior of reduction waves of Cd(Ⅱ) in sodium tartrate solution up to pH 11.0 was discussed.
0.35um BCD 공정을 이용한 700V Double Resurf LDMOS Transistor 구현
문남칠(Nam-Chil Moon),전본근(Bon-Keun Jun),권경욱(Kyung-Wook Kwon),이창준(Chang-Jun Lee),김종민(Jong-Min Kim),김남주(Nam-Joo Kim),유광동(Kwang-Dong Yoo) 대한전자공학회 2010 대한전자공학회 학술대회 Vol.2010 No.6
We have developed nLDMOS with over 800V BV based on 0.35um technology using Double RESURF (REduced SURface Field) technology without extra layers & Epi wafer. This device is applied to power switch and level shifter for HVIC such as LED lighting, motor control IC, etc. Also, this paper presents the optimization condition for wide RESURF region regarding a robust breakdown voltage and low specific on-resistance.
釜山市 街路樹의 大氣汚染物質 및 鹽分의 濃度에 관한 硏究
남정칠,문추연,박승범 東亞大學校生命資源科學大學附設 農業資原硏究所 1996 農業生命資援硏究 Vol.5 No.1
This study was to investigate the element of SO₂, Pb, Zn, Cu, Fe, Mn, Cd and the NaCl concentration in the leaves. The object of this study was Ginkgo biloba, Pinus thunbergii, Platanus occidentalis, Pruns yedoensis and camellia japonica, and these were planted in the city of Pusan. The study considered such factors as the sort of the tree, the month of the survey, the position of the tree. The results of this finding are as follows: The factor of the month indicated that regardless of the sort, the changing quantity of the SO₂ for all surveryed trees continued to increase as the time from Spring to Autumn passed. Particularly, the increase happened to the case of Ginkgo biloba and Platanus occidentalis, but was slow in Pruns yedoensis, Camellia japonica and Pinus thunbergii. SO₂-related standing was placed as follows: Ginkgo biloba for 0.65%, Platanus occidentalis for 0.56%, Pruns yedoensis for 0.31%, Camellia japonica for 0.27% and Pinus thunbergii for 0.25%. For the average content of heavy metal in the leaves the research founded the Fe for 298.5ppm, Mn for 28.2ppm, Zn for 24.9ppm, Cu for 6.8ppm, Cd for 1.44ppm and Pb for 0.91ppm. The Ginkgo biloba out of the surveyed trees indicated the high content of Fe and Cu, and the Platanus occidentalis recorded the high percentage of Mn, Zn and Cd. The findings thus concluded that based on the absorption and accumulation of SO₂ and each heavy metal, Ginkgo biloba and Platanus occidentalis are considered as the best street trees planted in the city. The NaCl concentration of the surveyed areas were proportional to the distance of the seaside. Specifically, the NaCl concentration of June was higher than that of April. The lowest was in August and the highest in October. The standing for the trees was placed as followe: Ginkgo biloba, Pinus thunbergii, Platanus occidentalis, Pruns yedoensis and Camellia japonica.
Woo, Sung-Chil,Kim, Gi-Young,Lee, Chang-Min,Moon, Dong-Oh,Kim, Hyung-Keun,Lee, Tae-Hyung,Moon, Yu-Seok,Park, Nam-Chul,Yoon, Man-Soo,Lee, Kyu-Sub,Park, Yeong-Min Landes Bioscience 2005 Cancer Biology & Therapy Vol.4 No.12
<P>Immunization of dendritic cells (DC) pulsed with tumor antigen can activate tumor-specific cytotoxic T lymphocytes (CTL) which are responsible for protection from tumor challenge and regression of established metastatic tumor. It has been hypothesized that tumor lysate contains factors that may modulate DC maturation. In this study, we examined whether the uptake of tumor lysate (MCA-102 fibrosarcoma) could modulate DC phenotypes in vitro and whether the administration in vivo of tumor lysate-pulsed DC (TP-DC) could elicit efficient tumor specific immune responses followed by a regression of established tumor burdens. It was investigated the uptake of tumor lysate by DC by means of flow cytometry and fluorescent microscope. Murine bone marrow-derived DC efficiently phagocytosed tumor lysate and after the uptake, the phenotype of TP-DC was surprisingly comparable to unpulsed-DC (UP-DC), exhibiting lower levels of CD80 (<51%), CD86 (<43%), and MHC class II (<59%). Also, TP-DC did not enhance secretion of IL-12p70 (UP- vs. TP; 54.5+/-6.4 vs. 50.5+/-4.8 pg/ml, respectively), contrary to those activated with LPS (113.6+/-16.8 pg/ml). However, TP-DC vaccination in vivo increased the IFN-gamma production from splenocytes higher than that of UP-DC (TP- vs. UP-DC; 41029+/-1523 vs. 4752+/-590 pg/ml, respectively). Furthermore, the administration of TP-DC enhanced specific T cell responses against MCA-102 fibrosarcoma. These results demonstrate that augmentation of DC phenotype and function in vitro is not necessarily a prerequisite for TP-DC vaccination to successfully promote anti-tumor immunity in vivo.</P>
충북 괴산 덕평리 일대 흑색셰일 및 흑색점판암기원 토양의 점토광물 조성 및 중금속원소의 분산
전철민,문희수,최선경,우남칠,Chon, Chul-Min,Moon, Hi-Soo,Choi, Sun Kyung,Woo, Nam Chil 대한자원환경지질학회 1997 자원환경지질 Vol.30 No.6
Concentrations of several heavy metals in soils derived from black shale and slate have been reported to be higher than the average concentrations in non-polluted soils. This study describes and characterizes soil minerals, and investigates the distribution of heavy metals in soils, and then examines their relationship. Soils in the study area are mainly consist of guartz and feldspars with minor amount of kaolin, illite, vermiculite, chlorite and illite-vermiculite interstratified minerals. Mineral compositions are similar in mountain-, farmland-, and paddy-soils. The residual soils derived from sandy phyllites contain less illites than those from black shale and black slate. Heavy metals appear to be more concentrated in soils than in rocks. The concentrate ratios in soils to rocks ranges 1.1 times for Cr, 2 for Cu, 1.4 for Ni. The contour maps of Cd, Zn, Pb, Cu contents using 0.43N $HNO_3$-extraction imply that these elements are highly concentrated in the soils near the past uranium exploration region, coal seams, black slate beds and tailings than other parts of the study area. The proportions of the day in most soils are less than 10%. In spite of small proportions of the clay, the concentrations of heavy metals from clay fractions to the total concentrations are high: 1~2.4 times for Co, 1.4~2.5 for Cu, 1.2~2.6 for Ni, 1~5 for Pb, 1~2.7 for Zn and 1.6~1.8 for Cr and V. The contents of organic carbons in clay fractions are also 1.5~3.9 times higher than in silt and sand fractions. Cu, Pb and organic carbons show positive relationship in all size fractions. In the size-fractionated soil profile samples, the contents of heavy metals and organic carbons show analogous trends with depth. For the clay fractions of soil profile samples, the contents of heavy metals with depth have analogous trends to abundances of vermiculites, which have the high CEC in main clay minerals.
신규 세파로스포린 항생제 DWC-751 의 in vitro 항균작용
심점순,최응칠,최문정,유영효,박남준,김병오 한국응용약물학회 1993 Biomolecules & Therapeutics(구 응용약물학회지) Vol.1 No.2
We compared in vitro antibacterial activity of DWC-751, a new parenteral cephalosporin antibiotic, with those of cefpirome (CPR), cefotaxime (CTX) and ceftazidime (CAZ). DWC-751 showed a broad antimicrobial spectrum against Gram-positive and negative bacteria The antibacterial activity of DWC-751 against Stapylococcus aureus was equal to that of CPR and superior to those of CTX and CAZ. The activity of it against Escherichia coli was more potent than those of CPR, CTX and CAZ. Against Pseudomonas aeruginosa, DWC-751 was slightly inferior to that of CAZ and superior to those of CPR and CTX. The antibacterial activity of DWC-751 was superior to those of CPR, CTX and CAZ against clinical isolates and ofloxacin resistant strains. DWC-751 showed bactericidal action against Escherichia coli at concentrations close to the MIC and induced the formation of filament and burge and lysis of Escherichia coli in a microscopic examination.