한국인 알코올 의존 환자에서 알코올 대사 효소 유전자형 빈도의 남녀 차이

김성곤,김철민,이덕기,황인복,이현숙,김성연,전은숙,송영상,박제민,최병무,김명정 大韓神經精神醫學會 2005 신경정신의학 Vol.44 No.2

Objectives : There are a number of preceding epidemiological studies reporting gender differences in the genetic etiology of alcohol dependence. The author investigated gender difference in the frequencies of ADH2 and ALDH2 genoypes between the patients with alcohol dependence and normal control. Methods : The subjects were 141 alcohol dependent patients (104 males, 37 females) and 138 normal control (79 males, 59 females). The frequencies of 1/1 and 1/2+2/2 (2+ afterward) genotypes for ADH2 and ALDH2 were investigated in male and female between alcohol dependence and normal control group. DNA was extracted from WBC in peripheral venous blood and PCR-RFLP method was used out for genotyping. Results : First, the frequency of ADH2 1/1 genotype was significantly higher in alcohol dependent patients than normal control in both genders. Second, while there was no gender difference in the frequency of ADH2 1/1 genotype in normal controls, in the patient group however, the frequency was significantly higher in females than males. Third, in male subjects with alcohol dependence, the frequency of ALDH2 1/1 genotype was significantly higher than in male normal control subjects. On the other hand, in female subjects with alcohol dependence, the frequency of ALDH2 2+ genotype was significantly higher than in female normal control subjects. Conclusion : These results suggest that while the risk of alcohol dependence is predominantly affected by ALDH2 1/1 geno-type in male, the female ADH2 1/1 genotype is mainly associated with the risk of alcohol dependence. This means that there are gender differences in the genetic etiology of alcohol dependence.

1,2 디아미노알칸을 포함하는 코발트(Ⅲ)착물의 합성과 분리에 관한 연구

都命基,金奉坤 嶺南大學校府設 基礎科學硏究所 1983 基礎科學硏究 Vol.3 No.-

[Co(en)(pn)₂]I₃ and [Co(Pn)₃]I₃ containing ethylenediamine (en) in EDTA and 1,2-diaminopropane(pN) was isolated from the reaction of [Co(EDTA)]-with 1,2-diamino-propane in aqueous solution by sp-sephadex c-25, cation exchange resin. The structure and composition of these complexes have been determined by means of elemental analysis, ir, electronic absorption spectroscopy. From these results, We have been suggested the new substitution mechanism of the reactions of [Co(EDTA)]-with 1,2-diaminopropane.

從屬理論의 不適實性 : 臺灣의 경우

金麟坤,劉明喆 경북대학교 교육대학원 1987 논문집 Vol.19 No.-

The case of Taiwan represents a challege to two predictions from dependency theory: that foreign economic penetration leads to slow economic growth and also to heightened inequality. Taiwan has received massive foreign aid and investment, but it has also had one the highest sustained rates of growth in the world, while income inequality on the island has decreased substantially. An examination of this deviant case is pursed by consideration of the various mechanisms dependency theorists claim are responsible for the linkage of foreign economic penetration to stagnation and inequality. The reasons are complex and varied; the involve features of the Japanese colonial experience, the nature of mainlander rule in Taiwan, the labor-intensive growth strategy pursued, the lack of strong foreign investment and trading stakes in early postwar Taiwan. A variety of factors made it possible for foreign economic dependency to exist without seriously retarding economic growth on Taiwan. Factors such as the well-developed rural infrastructure, a high rate of literacy, labor intensive development in firms without strong advantage of scale, the absence of powerful traditional elites dominating the government, and Taiwan's extraordinarily rapid rate of growth all helped to guarantee that income distribution would improve over time, regardless of the importance of foreign economic ties. Consideration of Taiwan draws attention to flaws in the arguments of most dependency theorists and suggests a more optimistic picture for at least some developing societies that have to deal with foreign economic penetration.

러시아어의 간접화법구문

손명곤 慶南大學校 人文科學硏究所 2002 人文論叢 Vol.15 No.-

여가활동 유형과 여가만족 및 생활만족의 관계

김승곤,양명환 濟州大學敎 體育科學硏究所 1995 체육과학연구 Vol.1 No.-

The purpose of this study was to determine the relationship of leisure activity types, leisure satisfaction and life satisfaction among college students. Specifically, two purposes were established for this study. The first purpose was to examine the effects of gender, age and types of leisure activity on leisure satisfaction and life satisfaction. The second purpose was to examine a casual relationship among types of leisure activity, leisure satisfaction, and life satisfaction. The subjects in this study were 115 male and 109 female college students. A purposive sampling method was used to select subjects who participated in three leisure activities including sport & exercise program(n=70,31.3%), hobby & creative activity(n=68, 30.4%),and amusement activity(n=86, 38.4%). Data were collected from all subjects during the fall of 1995. The Leisure Satisfaction Scale(Ragheb & Beard, 1980)was used to provide a measure of the extent to which individuals perceive that certain needs are met or satisfied through leisure activities. Life satisfaction was assessed by using a semantic differential technique. A 5 point Likert response scale was adopted for the instruments. One-way MANOVA, ANOVA and multiple regression analyses were used for research problems testing. MANOVAs indicated that gender, age, and leisure activity type had a significant effects on leisure satisfaction. Posttesting showed that male group perceived significantly higher in leisure satisfaction(psychological, educational, social, relaxational physio1ogical)than female group. The higher the age, the greater the leisure satisfaction(psychologica1, educational, social, relaxational physiological), and sport activity group perceived more leisure satisfaction (psychological, educational, social, relaxational, physiological, physical environment)than did the hobby & creative activity group and amusement group. ANOVA indicated that gender, age, leisure activity types had a significantly effects on life satisfaction. The male group perceived significantly higher in life satisfaction than female group. Scheffe multipe comparison indiacted that the higher the age, the greater the life satisfaction, and sport activity group perceived more life satisfaction than did the hobby & creative activity group and amusement group. Also multiple regression analysis and path analysis revealed that life satisfaction could be the best predicted from leisure satisfaction and could be affected through the sport activity indirectly. The findings provide significant casual relationships among leisure activity type, leisure satisfaction and life satisfaction in college students.

근적외 부광분석법에 의한 한국산 쌀의 성분분석

신명곤 우송대학교 1996 우송대학교 논문집 Vol.1 No.-

1993년도에 수확된 39종의 쌀을 이용하여 쌀의 식미와 관련이 높은 수분, 단백질, 아밀로오스 및 취반액 요오드쟁색도에 대해 근적외분광분석법을 활용한 측정가능성을 검토하였다. 이 화학적 분석방법의 실험결과와 근적외분광분석법에 의한 흡광도 데이터로부터 다중회귀분석을 행한 결과, 백미의 수분, 단백질, 아밀로오스 및 취반액 요오드정색도의 설명계수(r)는 각각 0.974, 0.972, 0.450 및 0.585이었으며, 각 성분의 측정오차(SEP)는 0.10, 0.15, 0.81 및 0.05를 나타내었다. 따라서 쌀의 수분 및 단백질함량은 근적외분광분석법에 의해 비파괴적으로 측정이 가능하였으나, 아밀로오스 및 요오드 정색도의 정량시에는 정확도가 낮음을 알 수 있었다. 한편, 분쇄된 쌀의 수분함량은 근적외분광분석법에 의해 신속하게 정량이 가능하였으나 분쇄과정중 발생되는 수분감소로 인해 분쇄전 쌀의 수분함량측정에는 한계가 있음을 알 수 있었다. Near-Infrared Reflectance Spectroscopy(NIR) in determining moisture, protein, amylose and iodine blue value was applied. The standard error of calibration(SEC) of moisture, protein, amylose and iodine blue value was 0.1327, 0.1319, 0.7702 and 0.0280, respectively. The results also showed that protein content in milled rice could be precisely analyzed by NIR, but the accuracy for determining moisture, amylose and iodine blue was not acceptable.

복합레진 수복물의 미세누출 감소를 위한 레진 전색제의 효과

조영곤,김문홍,이명구 大韓齒科保存學會 2006 Restorative Dentistry & Endodontics Vol.31 No.4

본 연구의 목적은 5급 복합레진 수복물에 각종 레진 전색제를 적용한 후, 수복물의 교합면측과 치은측 변연 미세누출 에 대한 레진 전색제의 감소효과를 평가하기 위하여 시행하였다. 40개의 발거된 대구치의 협면 치경부 5급 와동을 형성하고 복합레진을 충전한 후, 사용된 레진 전색제에 따라 다음과 같은 4개의 군으로 분류하였다; 복합레진 표면과 변연부에 레진 전색제를 적용하지 않은 대조군, 복합레진 표면과 번연부에 각각 레진 전색제를 적용한 Fortify Plus 군, BisCover 군 및 PermaSeal 군으로 분류하였다. 각 군의 시편을 실온의 증류수에 24시간 동안 보관한 후, 5℃와 55℃에서 1,000회의 열 순환을 시행하고 2% methylene blue 용액에 4시간 동안 침적시켰다. 각 치아는 저속의 diamond disk를 이용하여 각 수복물의 중앙부를 따라 협, 설 방향으로 양분하고 20배율의 광학 입체 현미경 하에서 각각 교합면측과 치은측 변연 미세누출을 평가하였다. 각 군의 교합면측과 치은측 변연 미세누출에 대한 유의성을 검정을 시행하여 다음과 같은 결과를 얻었다. 1. 교합면측 변연 미세누츨은 사용된 레진 전색제 간에 통계학적으로 유의한 차이를 나타내지 않았다. 2. 치은측 변연 미세누출은 대조군과 Fortify Plus 군이 PermaSeal 군보다 통계학적으로 높게 나타났으며, 또한 Fortify Plus 군은 Biscover 군보다 통계학적으로 높은 변연 미세누출을 나타내었다 (p < 0,05). 3. 대조군과 Fortify Plus 군은 교합면측 보다 치은측 변연에서 통계학적으로 더 높은 미세누출을 나타내어다 (p < 0.05). 4. BisCover 군과 PermaSeal 군은 교합면측과 치은측의 변연 미세누출 간에 통계학적으로 유의한 차이를 나타내지 않았다. 본 연구를 종합하면, 5급 복합레진 수복물의 교합면측 변연 미세누출에 대한 레진 전색제의 감소효과는 크게 나타나지 않았지만, 치은측 변연 미세누출에 대한 레진 전색제의 감소효과는 사용된 레진 전색제에 따라 서로 다르게 나타났다. The purpose of this study was to compare the ability of three resin surface sealants to prevent microleakage in Class V composite resin restorations. Forty Class V cavities with the occlusal margin in enamel and ginggival margin in dentin were prepared on the buccal surfaces of sound extracted molars, and restored with composite resin. Restorations were randomly assigned into one of four equal groups (n = 10) : a control group, without resin sealing, and three experimental groups in which margins were sealed with Fortify Plus, Biscover and Permaseal, respectively. Specimens were thermocycled, immersed in a 2% methylene blue solution for 4 hours, sectioned longitudinally, and observed the leakage at the occlusal and gingival margins. The result was analyzed using Kruskal-Wallis test, Mann-Whitney test and Wilcoxon signed rank test. In conclusion, the ability to reduce microleakage at occlusal margins was similar in all of three sealants. However at gingival margin, it depended on the type of used resin surface sealant. At gingival margin, control and Fortify Plus group showed statistically higher microleakage than PermaSeal group. and Fortify plus group also showed higher microleakage than BisCover group (p < 0.05). 〔J Kor Acad Cons Dent 31(4):282-289, 2006〕

다이아몬드 기구로 삭제한 와동에서 2단계 접착제의 미세누출 비교

이명구,조권환,조영곤 대한치과보존학회 2007 Restorative Dentistry & Endodontics Vol.32 No.5

중소기업형 CIM시스템 구축을 위한 생산계획수립 및 실적파악 모듈

최후곤,신완선,장중순,서준성,여명구,안동근,김진봉 成均館大學校 科學技術硏究所 1996 論文集 Vol.47 No.2

This study Focuses on developing several modules involved in an integrated production information system for medium- or small-sized industries. The modules of order management, quality control, production scheduling, and shop management are executed for an example case industry. The potential values of this research includes that the major information modules to collect, analysis, and display production data and shop data for constructing the computer integrated manufacturing system(CIMS) are programmed with various features of medium- or small-sized industries

東學運動과 甲午改革

金麟坤,劉明喆 경북대학교 1984 새마을 硏究論叢 Vol.4 No.-

The purpose of this paper is to explain that the reform bills of maladministration of Tonghak Movement were carried out autonomously throughout the period of the Kabo Reformation, and were later reflected in the Kabo Reformation. The Kabo Reformation was able to have autonomy and independence not only(1) because Japan at that time was absorbed in the pursuit of interests and worried about the intervention of Russia and other countries but also(2) because Daeweongun and the Gyojeong Office had autonomy. With such results of the autonomous Reformation Movement, the Kabo Reformation was able to (1) defeat the feudalistic elements, (2) bring about the development of systems of modern countries, and (3) finally helped Korea to be modernized in every field.