Pathogenecity of insect pathogenic fungus Isaria fumosorosea to different aphid species

Muhammad Naeem Malik,Shoaib Freed,Hafiza Tahira Gul,Muhammad Akmal 단국대학교 국제농업협력연구소 2012 단국대학교 국제농업협력연구소 학술대회 Vol.2012 No.1

In the current research, the insect pathogenic fungus, Is aria fumosorosea was assessed for its pathogenecity against adults of different aphid species of wheat and Brassica crop i.e. Schizaphis graminum, Rhopalosiphum padi, Brevicoryne brassicae and Lipaphis erysimi. I. fumosorosea (IF-01) was found effective at all concentrations i.e. 1x106, 1x107 and 1x108 spores/ml on all aphid species, but the uppermost concentration (lx108 spores/ml) provided maximum control within short period of time (P < 0.05). The results showed that the effect of I. fumosorosea on different aphid species was dose and time dependent. I. fumosorosea with LC50 value of 9.02 x 105 proved to be lethal to L. erysimi after 3rd day. Mortality of B. brassicae was observed maximum on highest concentration of 1x108 spores/ml with LC50 value of 1.64 x 107 , while the LT50 values were in range of 1.78-4.53 days for different aphid species treated at various concentrations. By checking the field efficacy of I. fumosorosea against aphid species, this entomopathogenic fungus can be used as possible biological control agent for suppressing aphids.

Simultaneous Equations and Endogeneity in Corporate Finance: The Linkage between Institutional Ownership and Corporate Financial Performance

MALIK, Qaisar Ali,HUSSAIN, Shahzad,ULLAH, Naeem,WAHEED, Abdul,NAEEM, Muhammad,MANSOOR, Muhammad Korea Distribution Science Association 2021 The Journal of Asian Finance, Economics and Busine Vol.8 No.3

The objective of this research is to explore the inconclusive theoretical and empirical association between institutional ownership and firm performance in the context of emerging Pakistani economy. The data set consists of all the non-financial firms listed on the Pakistan Stock Exchange (PSX). Annual data set covers the period ranging from 2010 to 2015. However, the econometric analysis does not include those firms with incomplete data. Thus the final data set comprised of an unbalanced panel of sample of 276 firms with 1231 firms years observations. Data related to the institutional ownership and other variables taken for the study were extracted through the annual financial reports of the firms. The research used Tobin's Q as a proxy of market measure of firm performance and tested the endogenous relation with institutional ownership through OLS and 2SLS approach. The study also applied Durbin-Wu-Hausman test to determine the endogeneity before analyzing the 2SLS model. The Durbin-Wu-Hausman Test (DWH) conform the endogenous link between institutional ownership and performance and vice versa. The results derived from 2SLS also confirm a highly significant relationship and two way direct proportional relationships between the institutional investment and corporate performance in the studied companies.

Case-Control Study of Diet and Prostate Cancer in a Rural Population of Faisalabad, Pakistan

Bashir, Muhammad Naeem,Malik, Muhammad Akram Asian Pacific Journal of Cancer Prevention 2015 Asian Pacific journal of cancer prevention Vol.16 No.6

Background: The effects of diet on epidemiology of prostate cancer are inconclusive. Therefore a hospitalbased, case-control study was conducted in a rural population of Faisalabad, Pakistan, to examine the impact of dietary factors on risk of cancer development. Materials and Methods: This study was based on 102 confirmed cases of prostate cancer and 204 normal controls. Logistic regression was used to estimate odds ratios and 95% confidence intervals for odds ratios to evaluate the relationship between prostate cancer and diet. Results: Consumption of red meat and fat items significantly increased the prostate cancer risk having odds ratios and 95% confidence intervals of 3.41; 1.46-7.96 and 2.45; 1.17-5.15, respectively. On the other hand, more consumption of vegetables, fluid intake and fruit significantly decreased the prostate cancer risk (odd ratios and corresponding 95% confidence intervals of 0.21; 0.10-0.44, 0.10; 0.05- 0.19 and 0.09; 0.03- 0.23, respectively. Conclusions: The present study supports the hypothesis that frequent consumption of red meat and fat items may increase prostate cancer risk while more intake of fruit, vegetables and fluid intake may protect against prostate cancer in the relatively low risk group in rural Pakistan.

Risk Factors of Prostate Cancer: a Case-control Study in Faisalabad, Pakistan

Bashir, Muhammad Naeem,Ahmad, Muhammad Riaz,Malik, Akram Asian Pacific Journal of Cancer Prevention 2014 Asian Pacific journal of cancer prevention Vol.15 No.23

Background: Prostate cancer is the third most commonly diagnosed cancer among males in Pakistan but very little is known about risk factors among the Pakistani population. Therefore a hospital-based, case-control study was carried out in Faisalabad to identify potential risk factors. Materials and Methods: This study was based on 140 prostate cancer cases and 280 normal controls. Logistic regression was used to estimate odds ratios and 95% confidence intervals for odds ratios to assess the relationship between prostate cancer and different risk factors. Results: Family history of prostate cancer, age, smoking, obesity, consumption of red meat and frequent use of fat items significantly increased the prostate cancer risk (odds ratios and 95% confidence intervals of: 7.32; 1.79-29.8; 16.9, 5.60-50.8; 2.47, 1.17-5.18; 5.79, 2.66-12.6; 2.71, 1.07-6.91; and 3.39, 1.47-7.83, respectively. On the other hand, more consumption of fruit, fluid intake and better lifestyle (physical activity) significantly reduced the risk of developing prostate cancer with odd ratios and corresponding 95% confidence intervals of: 0.27, 0.11-0.61; 0.05, 0.02-0.12; and 0.28, 0.13-0.58. Conclusions: The results of the present study suggested that age, family history of prostate cancer, smoking, obesity, fluid intake, frequent use of fat items, consumption of fruits and better lifestyle might be associated with prostate cancer among Pakistani males.

Initial-Dip Existence and Estimation in Relation to DPF and Data Drift

Kamran, Muhammad A.,Naeem Mannan, Malik M.,Jeong, Myung-Yung Frontiers Media S.A. 2018 Frontiers in neuroinformatics Vol.12 No.-

<P>Early de-oxygenation (initial dip) is an indicator of the primal cortical activity source in functional neuro-imaging. In this study, initial dip's existence and its estimation in relation to the differential pathlength factor (DPF) and data drift were investigated in detail. An efficient algorithm for estimation of drift in fNIRS data is proposed. The results favor the shifting of the fNIRS signal to a transformed coordinate system to infer correct information. Additionally, in this study, the effect of the DPF on initial dip was comprehensively analyzed. Four different cases of initial dip existence were treated, and the resultant characteristics of the hemodynamic response function (HRF) for DPF variation corresponding to particular near-infrared (NIR) wavelengths were summarized. A unique neuro-activation model and its iterative optimization solution that can estimate drift in fNIRS data and determine the best possible fit of HRF with free parameters were developed and herein proposed. The results were verified on simulated data sets. The algorithm is applied to free available datasets in addition to six healthy subjects those were experimented using fNIRS and observations and analysis regarding shape of HRF were summarized as well. A comparison with standard GLM is also discussed and effects of activity strength parameters have also been analyzed.</P>

Colorectal carcinoma and chronic inflammatory demyelinating polyneuropathy: is there a possible paraneoplastic association?

Adnan Malik,Faisal Inayat,Muhammad Hassan Naeem Goraya,Gul Nawaz,Ahmad Mehran,Atif Aziz,Saad Saleem 대한소화기내시경학회 2023 Clinical Endoscopy Vol.56 No.2

A plethora of paraneoplastic syndromes have been reported as remote effects of colorectal carcinoma (CRC). However, there is a dearth of data pertaining to the association of this cancer with demyelinating neuropathies. Herein, we describe the case of a young woman diagnosed with chronic inflammatory demyelinating polyneuropathy (CIDP). Treatment with intravenous immunoglobulins and prednisone did not improve her condition, and her neurological symptoms worsened. Subsequently, she was readmitted with exertional dyspnea, lightheadedness, malaise, and black stools. Colonoscopy revealed a necrotic mass in the ascending colon, which directly invaded the second part of the duodenum. Pathologic results confirmed the diagnosis of locally advanced CRC. Upon surgical resection of the cancer, her CIDP showed dramatic resolution without any additional therapy. Patients with CRC may develop CIDP as a type of paraneoplastic syndrome. Clinicians should remain cognizant of this potential association, as it is of paramount importance for the necessary holistic clinical management.

Pollination biology of Callistemon viminalis (Sol. Ex Gaertn.) G. Don (Myrtaceae), Punjab, Pakistan

Abdul Latif,Naeem Iqbal,Muhammad Ejaz,Saeed Ahmad Malik,Allah Bakhsh Gulshan,Abid Mahmood Alvi,Khaliq Dad 한국응용곤충학회 2016 Journal of Asia-Pacific Entomology Vol.19 No.2

A research was conducted to find out the floral traits and pollinator's community of bottle brush (Callistemon viminalis: Myrtaceae). Total numbers of pollen grains, pollen grain viability, stigma receptivity, nectar volume and nectar concentration, numbers of ovules and pollen/ovule ratio were recorded. The pollinators' abundance, visitation rate and frequency were also observed. In field experiment, capsule weight, seed setting and seed numbers in open and caged flowers were also evaluated. The results revealed a total of 128,139 pollen grains/ flower. Among total pollen grains, viable pollen grains were 84.3% and non-viable were 15.69%. There were 275 ovules/flower and pollen ovule ratio was 472.50. Stigma receptivity was decreased with the age of the flowers and stigma remained receptive for about 6 days. The nectar volume and nectar concentration were 13 μL and 29%, respectively. The flowers were visited by nine Hymenopteran, four Lepidopteran, one Dipteran and one bird species. Among all pollinators, bees represented the most abundant species (1290) and showed the highest visitation rate (3.6–13.8 numbers of flowers/min) and visitation frequency (0.22–1.92 individuals/ branch/5 min). Open-pollinated flowers showed statistically higher capsule weight (0.0824 ± 0.001), seed setting (0.052 ± 0.0001) and seed numbers (242.4 ± 2.87) as compared to flowers in cages.

Detection of BCR/ABL Fusion Gene by Hematological and Cytogenetical Analysis in Chronic Myeloid Leukemia Patients in Quetta, Pakistan

Tahira, Bibi,Asif, Muhammad,Khan, Samiullah,Hussain, Abrar,Shahwani, Muhammad Naeem,Malik, Arif,Inayatullah, Syed,Iqbal, Zafar,Rasool, Mahmood Asian Pacific Journal of Cancer Prevention 2015 Asian Pacific journal of cancer prevention Vol.16 No.9

Background: Chronic myeloid leukemia (CML) is a myeloproliferative disorder of pluripotent stem cells, caused by reciprocal translocation between the long arms of chromosomes 9 and 22, t(9;22)(q34;q11), known as the Philadelphia chromosome. Materials and Methods: A total of 51 CML patients were recruited in this study. Complete blood counts of all CML patients were performed to find out their total leukocytes, hemoglobin and platelets. FISH was performed for the detection of BCR-ABL fusion and cryptogenic tests using bone marrow samples were performed for the conformation of Ph (9;22)(q34;q11) and variant translocation mechanisms. Results: In cytogenetic analysis we observed that out of 51 CML patients 40 (88.9%) were Ph positive and 4 (8.88%) had Ph negative chromosomes. Mean values of WBC 134.5 $10^3/{\mu}l$, hemoglobin 10.44 mg/dl, and platelets 288.6 $10^3/{\mu}l$ were observed in this study. Conclusions: In this study, Ph positive translocation between chromosome (9:22)(q34;q11) were observed in 40 (88.9%) CML patients.