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- 저자 : Motoki Koide (검색결과 3 건)
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Takafumi Hiranaka,Takaaki Fujishiro,Motoki Koide,Koji Okamoto 대한정형외과학회 2023 Clinics in Orthopedic Surgery Vol.15 No.4
This technical note demonstrates kinematically aligned Oxford unicompartmental knee arthroplasty using the Microplasty instrumentation system with custom-made devices. The medial joint line is evaluated preoperatively; if it is aligned and parallel with the lateral joint line, they are considered to comprise the coronal knee joint line (CJL). In this case, the coronal inclination of a spoon gauge inserted into the medial joint space indicates the CJL. Otherwise, an accessory spoon is inserted and connected to the medial spoon to refer to the posterior condylar line, which is considered the CJL. The tibial cutting block is then connected without changing the inclination of the spoon and the coronal tilt of the tibial extramedullary rod is adjusted, which is implemented with a custom-made ankle yoke. The remainder of the steps is then identical to the conventional Microplasty procedure. This technique can imitate the cutting line to the CJL, which might be considered ideal from mechanical and kinematic perspectives.
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Yeunhwa Gu,Ikukatsu Suzuki,Motoki Koide,Ikuo Hayash,Hideyuki Takai,Ahn,Kyoo-seok,Hajimu Yamamoyo INSTITUTE OF ORIENTAL MEDICINE KYUNG-HEE UNIVERSIT 1999 JOURNAL OF ORIENTAL MEDICINE Vol.4 No.1
Propolis is a resin-like material produced by honeybees, an mixture with resin and pollen in their saliva. Propolis, in Oriental medicine, has been referred to as 'Nobongbang'(露蜂房)and used for anti-pyretic, antidotal, analgesic, and anti-inflammatory purpose. The pharmacological effects of Propolis are known to be anti-bacterial, anti-inflammatory, anti-tumor, and immunopotentiating. Propolis was extracted with water, the extract was centrifuged, and the supernatant was filtered and freeze-dried. It was then gel-filtered and purified according to the increase in the ratio of mouse lymphocytes versus polymorphonuclear leukocytes(L/P activity). We previously reported the immunopotentiating effects of Propolis at the 114the General Conference of the Japan Society of Pharmacology(March, 1994 : Tokyo) and its anti-tumor effects on solid and ascitic tumors in mice bearing Ehrlich carcinoma at the 53rd General Conference of the Japanese Cancer Association(October, 1994 : Nagoya). Furthermore we reported the anti-tumor and anti-cytopenic effects of combined use of water-soluble Propolis and its gel-filtration fractions G-1, G-2, and G-3 with anti-cancer drugs(5FU and MMC) in ICR mice(5-week-old males) bearing Ehrlich carcinoma at the 115th General Conference of the Japan Society of Pharmacology(March, 1995 : Sendai). The tumor growth was inhibited, and cytopenia due to 5FU was significantly alleviated(Pr.<0.01 for WBS and RBC), when water-soluble Propolis was administered with 5FU as compared with 5FU alone(inhibition rate 83.0%). When water-soluble Propolis and its gel-filtration fractions G-1 and G-2 were administered with MMC, the tumor growth was more suppressed(inhibition rates 91.8%, 88.0%, and 82.0%, respectively) than by intraperitoneal administration of MMC alone. In addition, leukopenia was significantly alleviated(Pr.<0.05) by administration of water-soluble and G-2 with MMC as compared with MMC alone(54th General Conference of the Japan Cancer Society : Oct., 1995 : Kyoto). Aithouse, the active component responsible for the anti-tumor activity of water-soluble Propolis has been identified, and its anti-tumor effects likely to be derived from stimulation of host responses as well as direct effects on cancer cells, because water-soluble Propolis and its gel-filtration fractions increased the L/P activity and antibody-producing cells(PFC activity). Water-soluble Propolis, G-1 and G-2 had preventive effects on cytopenia induced by anti-cancer drugs, probably because they exert stimulatory effects on hemopoietic functions via cytokines such as IL-6 and IL-11. We intended to analyze components of G-1 and G-2, which showed potent anti-tumor effects, by high-performance liquid chromatography.
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Matsui, Tetsuya,Nakao, Katsuhiro,Higa, Motoki,Tsuyama, Ikutaro,Kominami, Yuji,Yagihashi, Tsutomu,Koide, Dai,Tanaka, Nobuyuki Springer Japan 2018 Ecological research Vol.33 No.2
<P><B>Abstract</B></P><P>Climate change will likely change the species composition or abundance of plant communities, and it is important to anticipate these changes to develop climate change adaptation policies. We chose beech (<I>Fagus crenata</I> Blume) and its competitive tree species as target species to evaluate potential turnover in forest types under climate change using a multivariate classification tree model. To construct the model, geographical presence/absence data for nine target species were used as multivariate response variables, with five climatic factors were used as predictor variables. Current and future distribution probabilities for the target species were calculated, and the 15 dominant forest types were subjectively classified in approximately 1‐km<SUP>2</SUP> grid cells within the area of the current beech forest distribution. All 16,398 grid cells of the beech‐dominant forest type (FCR‐QCR) were projected to be replaced in the future by five <I>Quercus crispula</I>‐dominant types (59% of FCR‐QCR grid cells), four <I>Q. serrata</I> types (22%), two <I>Q. salicina</I> types (8%), or two <I>Abies firma</I> types (0.1%). The FCR‐QCR type remained unchanged (stable) in only 11.4% of grid cells; these were mainly distributed at high elevations in snowy areas on the Sea of Japan side of the country. In contrast, vulnerable habitats (future probability of beech occurrence less than 1.0%) were found at low elevations on both the Sea of Japan and the Pacific Ocean sides. Northwards or upwards range expansions or increases of <I>Quercus</I> spp., in particular, need to be carefully monitored.</P>
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