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- 저자 : Hideyuki Takai (검색결과 2 건)
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Emi Kondo,Eri Takai,Hiroyuki Sagayama,Hideyuki Takahashi 한국운동영양학회 2023 Physical Activity and Nutrition (Phys Act Nutr) Vol.27 No.1
[Purpose] Muscle glycogen storage before a race is necessary for endurance athletes to achieve the best performance. Generally, the recommended carbohydrate intake for preparation over 90 min of the race is 10–12 g·kg-1·day-1. However, it remains unclear whether an elite athlete with an already high-carbohydrate diet can further increase muscle glycogen through a very-high-carbohydrate intake. Therefore, we compared the effects of three types of glycogen loading in a 28-year-old male athlete who belongs to the top 50 racewalkers in the world, consuming a daily energy intake of 4507 kcal and a carbohydrate intake of 12.7 g·kg-1·day-1. [Methods] The racewalker consumed very-high-carbohydrate diets three times for 2 days each, 13.7 g·kg-1·day-1 for trial 1, 13.9 g·kg-1·day-1 for trial 2, and 15.9 g·kg-1·day-1 for trial 3. Muscle glycogen concentrations in the anterior (vastus lateralis and vastus intermedius) and posterior thighs (semimembranosus, semitendinosus, and biceps femoris) were measured using carbon-13 magnetic resonance spectroscopy. [Results] Muscle glycogen concentrations in both the anterior and posterior thighs increased in all trials, particularly in trial 3. Body mass also increased by 1.5 kg in trials 1 and 2 and by 1.8 kg in trial 3 before and after the trials. The participant felt satiated throughout the day and experienced stomach discomfort during trial 3. [Conclusion] We found that a 2-day very-high-carbohydrate diet and tapering of training could further increase the muscle glycogen concentration in athletes. However, we speculated that 15.9 g·kg-1·day-1 carbohydrate intake was unrealistic for the actual pre-race diet.
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Yeunhwa Gu,Ikukatsu Suzuki,Motoki Koide,Ikuo Hayash,Hideyuki Takai,Ahn,Kyoo-seok,Hajimu Yamamoyo INSTITUTE OF ORIENTAL MEDICINE KYUNG-HEE UNIVERSIT 1999 JOURNAL OF ORIENTAL MEDICINE Vol.4 No.1
Propolis is a resin-like material produced by honeybees, an mixture with resin and pollen in their saliva. Propolis, in Oriental medicine, has been referred to as 'Nobongbang'(露蜂房)and used for anti-pyretic, antidotal, analgesic, and anti-inflammatory purpose. The pharmacological effects of Propolis are known to be anti-bacterial, anti-inflammatory, anti-tumor, and immunopotentiating. Propolis was extracted with water, the extract was centrifuged, and the supernatant was filtered and freeze-dried. It was then gel-filtered and purified according to the increase in the ratio of mouse lymphocytes versus polymorphonuclear leukocytes(L/P activity). We previously reported the immunopotentiating effects of Propolis at the 114the General Conference of the Japan Society of Pharmacology(March, 1994 : Tokyo) and its anti-tumor effects on solid and ascitic tumors in mice bearing Ehrlich carcinoma at the 53rd General Conference of the Japanese Cancer Association(October, 1994 : Nagoya). Furthermore we reported the anti-tumor and anti-cytopenic effects of combined use of water-soluble Propolis and its gel-filtration fractions G-1, G-2, and G-3 with anti-cancer drugs(5FU and MMC) in ICR mice(5-week-old males) bearing Ehrlich carcinoma at the 115th General Conference of the Japan Society of Pharmacology(March, 1995 : Sendai). The tumor growth was inhibited, and cytopenia due to 5FU was significantly alleviated(Pr.<0.01 for WBS and RBC), when water-soluble Propolis was administered with 5FU as compared with 5FU alone(inhibition rate 83.0%). When water-soluble Propolis and its gel-filtration fractions G-1 and G-2 were administered with MMC, the tumor growth was more suppressed(inhibition rates 91.8%, 88.0%, and 82.0%, respectively) than by intraperitoneal administration of MMC alone. In addition, leukopenia was significantly alleviated(Pr.<0.05) by administration of water-soluble and G-2 with MMC as compared with MMC alone(54th General Conference of the Japan Cancer Society : Oct., 1995 : Kyoto). Aithouse, the active component responsible for the anti-tumor activity of water-soluble Propolis has been identified, and its anti-tumor effects likely to be derived from stimulation of host responses as well as direct effects on cancer cells, because water-soluble Propolis and its gel-filtration fractions increased the L/P activity and antibody-producing cells(PFC activity). Water-soluble Propolis, G-1 and G-2 had preventive effects on cytopenia induced by anti-cancer drugs, probably because they exert stimulatory effects on hemopoietic functions via cytokines such as IL-6 and IL-11. We intended to analyze components of G-1 and G-2, which showed potent anti-tumor effects, by high-performance liquid chromatography.
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