The Burden of Stroke in Kurdistan Province, Iran From 2011 to 2017

Moradi, Shahram,Moradi, Ghobad,Piroozi, Bakhtiar The Korean Society for Preventive Medicine 2021 예방의학회지 Vol.54 No.2

Objectives: The aim of this study was to calculate the burden of stroke in Kurdistan Province, Iran between 2011 and 2017. Methods: Incidence data extracted from the hospital information system of Kurdistan Province and death data extracted from the system of registration and classification of causes of death were used in a cross-sectional study. The World Health Organization method was used to calculate disability-adjusted life years (DALYs). Results: The burden of stroke increased from 2453.44 DALYs in 2011 to 5269.68 in 2017, the years of life lost increased from 2381.57 in 2011 to 5109.68 in 2017, and the years of healthy life lost due to disability increased from 71.87 in 2011 to 159.99 in 2017. The DALYs of ischaemic stroke exceeded those of haemorrhagic stroke. The burden of disease, new cases, and deaths doubled during the study period. The age-standardised incidence rate of ischaemic stroke and haemorrhagic stroke in 2017 was 21.72 and 20.72 per 100 000 population, respectively. Conclusions: The burden of stroke is increasing in Kurdistan Province. Since health services in Iran are based on treatment, steps are needed to revise the current treatment services for stroke and to improve the quality of services. Policy-makers and managers of the health system need to plan to reduce the known risk factors for stroke in the community. In addition to preventive interventions, efficient and up-to-date interventions are recommended for the rapid diagnosis and treatment of stroke patients in hospitals. Along with therapeutic interventions, preventive interventions can help reduce the stroke burden.

Enhancement of Soft Soil Behaviour by using Floating Bottom Ash Columns

Razieh Moradi,Aminaton Marto,Ahmad Safuan A Rashid,Mohammad Moeen Moradi,Abideen Adekunle Ganiyu,Mohamad Hafeezi Abdullah,Suksun Horpibulsuk 대한토목학회 2019 KSCE JOURNAL OF CIVIL ENGINEERING Vol.23 No.6

The current disposition worldwide is for sustainable construction, and the application of by-products is one of the ways to achieve it. In this research, bottom ash was used as a substitute material in a granular column to decrease settlement and enhance the bearing capacity of soft soil. Bottom ash is a derivate of the coal burning process, it has similar engineering properties to sand and fine gravel. A set of reduced scale physical modelling tests were performed on floating bottom ash columns to assess the improvement in the bearing capacity of the composite ground. The results clearly showed that the bearing capacity of the model soil was greatly improved with the installation of bottom ash column sand. There was an obvious enhancement of the load capacity of the granular columns when they were encased. The usage of bottom ash instead of aggregate or sand for granular columns will reduce the project cost and it aligns with the goal of sustainable construction development.

Effects of p53 Codon 72 and MDM2 SNP309 Polymorphisms on Gastric Cancer Risk among the Iranian Population

Moradi, Mohammad-Taher,Salehi, Zivar,Aminian, Keyvan,Yazdanbod, Abbas Asian Pacific Journal of Cancer Prevention 2014 Asian Pacific journal of cancer prevention Vol.15 No.17

Background: Development of gastric cancer (GC) is a multistep process that requires alterations in the expression of oncogenes and tumor suppressor genes, occurring over several decades. The p53 tumor suppressor protein is involved in cell-cycle control, apoptosis and DNA repair. One of the most important regulators of p53 is MDM2, which acts as a negative regulator in the p53 pathway. Based on the key role of p53 and MDM2 in tumor suppression, polymorphisms that cause change in their function might affect cancer risk. We therefore elevated associations of the polymorphisms of p53 (R72P) and MDM2 (SNP309) with GC in Iran. Materials and Methods: A total of 104 patients with gastric cancer and 100 controls were recruited. Genomic DNA was extracted from fresh gastric samples. Genotyping of the p53 and MDM2 genes was performed using allele specific PCR (AS-PCR). Results: There was no significant difference between the p53 codon 72 polymorphism distribution in control and patient groups (p=0.54), but the G allele of MDM2 was found to be over-represented in patients (p=0. 01, Odds Ratio=2. 08, 95% Confidence Interval= 1.37-4.34). Conclusions: The p53 R72P seems not to be a potential risk factor for development of GC among Iranian patients, but our data suggest that MDM2 SNP309 might modify the risk related to GC.

Geomechanical study of well stability in high-pressure, high-temperature conditions

Moradi, Seyyed Shahab Tabatabaee,Nikolaev, Nikolay I.,Chudinova, Inna V.,Martel, Aleksander S. Techno-Press 2018 Geomechanics & engineering Vol.16 No.3

Worldwide growth in hydrocarbon and energy demand is driving the oil and gas companies to drill more wells in complex situations such as areas with high-pressure, high-temperature conditions. As a result, in recent years the number of wells in these conditions have been increased significantly. Wellbore instability is one of the main issues during the drilling operation especially for directional and horizontal wells. Many researchers have studied the wellbore stability in complex situations and developed mathematical models to mitigate the instability problems before drilling operation. In this work, a fully coupled thermoporoelastic model is developed to study the well stability in high-pressure, high-temperature conditions. The results show that the performance of the model is highly dependent on the truly evaluated rock mechanical properties. It is noted that the rock mechanical properties should be evaluated at elevated pressures and temperatures. However, in many works, this is skipped and the mechanical properties, which are evaluated at room conditions, are entered into the model. Therefore, an accurate stability analysis of high-pressure, high-temperature wells is achieved by measuring the rock mechanical properties at elevated pressures and temperatures, as the difference between the model outputs is significant.

Prevalence of underweight and wasting in Iranian children aged below 5 years: a systematic review and meta-analysis

Moradi, Yousef,Shadmani, Fatemeh Khosravi,Mansori, Kamyar,Hanis, Shiva Mansouri,Khateri, Rozhin,Mirzaei, Hossein The Korean Pediatric Society 2018 Clinical and Experimental Pediatrics (CEP) Vol.61 No.8

Purpose: Wasting and underweight are the 2 main indicators of children's undernutrition. We aimed to estimate the prevalence of undernutrition at the national level in Iran. Methods: We performed a search for original articles published in international and Iranian databases including MEDLINE, Web of Science, Google Scholar, Scopus, CINHAL (Cumulative Index to Nursing and Allied Health Literature), Scientific Information Database, Irandoc, Iranmedex, and Magiran during January 1989-August 2017. Seven keywords, in English and Persian, including malnutrition, protein energy malnutrition, growth disorders, underweight wasting, weight loss, children below 5 years old, and children, were used to search the databases. Results: Finally, 17 articles were included in the meta-analysis, based on which the prevalence of underweight and wasting in Iranian children were estimated to be 11% and 5%, respectively. The prevalence rates of underweight among children in the central, western, southern, and northern parts of Iran and at the national level were 24%, 5%, 20%, 17%, and 6%, respectively. The prevalence rates of wasting in the central, western, southern, and northern parts of Iran and at the national level were 9%, 4%, 11%, 5%, and 4%, respectively. Conclusion: Although the prevalence of underweight and wasting in Iran was low, some parts of the country showed high prevalence. The main reason behind this difference in the prevalence of malnutrition may be due to the level of development in different regions.

Common endpoints of generalized weak contractive mappings via separation theorem with applications

Moradi, Sirous,Farajzadeh, Ali P,Cho, Yeol Je,Plubtieng, Somyot Springer (Biomed Central Ltd.) 2015 Fixed point theory and applications Vol.2015 No.1

Theoretical Study of Thiazole Adsorption on the (6,0) zigzag Single-Walled Boron Nitride Nanotube

Moradi, Ali Varasteh,Peyghan, Ali Ahmadi,Hashemian, Saeede,Baei, Mohammad T. Korean Chemical Society 2012 Bulletin of the Korean Chemical Society Vol.33 No.10

The interaction of thiazole drug with (6,0) zigzag single-walled boron nitride nanotube of finite length in gas and solvent phases was studied by means of density functional theory (DFT) calculations. In both phases, the binding energy is negative and presenting characterizes an exothermic process. Also, the binding energy in solvent phase is more than that the gas phase. Binding energy corresponding to adsorption of thiazole on the BNNT model in the gas and solvent phases was calculated to be -0.34 and -0.56 eV, and about 0.04 and 0.06 electrons is transferred from the thiazole to the nanotube in the phases. The significantly changes in binding energies and energy gap values by the thiazole adsorption, shows the high sensitivity of the electronic properties of BNNT towards the adsorption of the thiazole molecule. Frontier molecular orbital theory (FMO) and structural analyses show that the low energy level of LUMO, electron density, and length of the surrounding bonds of adsorbing atoms help to the thiazole adsorption on the nanotube. Decrease in global hardness, energy gap and ionization potential is due to the adsorption of the thiazole, and consequently, in the both phases, stability of the thiazole-attached (6,0) BNNT model is decreased and its reactivity increased. Presence of polar solvent increases the electron donor of the thiazole and the electrophilicity of the complex. This study may provide new insight to the development of functionalized boron nitride nanotubes as drug delivery systems for virtual applications.

Machine learning modeling and DOE-assisted optimization in synthesis of nanosilica particles via Stöber method

Moradi, Hiresh,Atashi, Peyman,Amelirad, Omid,Yang, Jae-Kyu,Chang, Yoon-Young,Kamranifard, Telma Techno-Press 2022 Advances in nano research Vol.12 No.4

Silica nanoparticles, which have a broad range of sizes and specific surface features, have been used in many industrial applications. This study was conducted to synthesize monodispersed silica nanoparticles directly from tetraethyl orthosilicate (TEOS) with an alkaline catalyst (NH₃) based on the sol-gel process and the Stöber method. A central composite design (CCD) is used to build a second-order (quadratic) model for the response variables without requiring a complete three-level factorial experiment. The process was then optimized to achieve the minimum particle size with the lowest concentration of TEOS. Dynamic light scattering and scanning electron microscopy were used to analyze the size, dispersity, and morphology of the synthesized nanoparticles. After optimization, a confirmation test was carried out to evaluate the confidence level of the software prediction. The results revealed that the predicted optimization is consistent with experimental procedures, and the model is significant at the 95% confidence level.

Underwater explosion and its effects on nonlinear behavior of an arch dam

Moradi, Melika,Aghajanzadeh, Seyyed Meisam,Mirzabozorg, Hasan,Alimohammadi, Mahsa Techno-Press 2018 Coupled systems mechanics Vol.7 No.3

In the present paper, the behavior of the Karaj double curvature arch dam is studied focusing on the effects of structural nonlinearity on the responses of the dam body when an underwater explosion occurred in the reservoir medium. The explosive sources are located at different distances from the dam and the effects of the cavitation and the initial shock wave of the explosion are considered. Different amount of TNT are considered. Two different linear and nonlinear behavior are assumed in the analysis and the dam body is assumed with and without contraction joints. Radial, tangential and vertical displacements of the dam crest are obtained. Moreover, maximum and minimum principal stress distributions are plotted. Based on the results, the dam body responses are sensitive to the insertion of joints and constitutive model considered for the dam body.

Socioeconomic Inequalities in the Oral Health of People Aged 15-40 Years in Kurdistan, Iran in 2015: A Cross-sectional Study

Moradi, Ghobad,Moinafshar, Ardavan,Adabi, Hemen,Sharafi, Mona,Mostafavi, Farideh,Bolbanabad, Amjad Mohamadi The Korean Society for Preventive Medicine 2017 Journal of Preventive Medicine and Public Health Vol.50 No.5

Objectives: The aim of this study was to evaluate socioeconomic inequalities in the prevalence of dental caries among an urban population. Methods: This study was conducted among 2000 people 15-40 years of age living in Kurdistan, Iran in 2015. Using a questionnaire, data were collected by 4 trained dental students. The dependent variable was the decayed, missing, and filled teeth (DMF) index. Using principal component analysis, the socioeconomic status (SES) of families was determined based on their household assets. Inequality was measured using the concentration index; in addition, the Oaxaca analytical method was used to determine the contribution of various determinants to the observed inequality. Results: The concentration index for poor scores on the DMF index was -0.32 (95% confidence interval [CI], -0.40 to -0.36); thus, poor DMF indices had a greater concentration in groups with a low SES (p<0.001). Decomposition analysis showed that the mean prevalence of a poor DMF index was 43.7% (95% CI, 40.4 to 46.9%) in the least privileged group and 14.4% (95% CI, 9.5 to 9.2%) in the most privileged group. It was found that 85.8% of the gap observed between these groups was due to differences in sex, parents' education, and the district of residence. A poor DMF index was less prevalent among people with higher SES than among those with lower SES (odds ratio, 0.31; 95% CI, 0.19 to 0.52). Conclusions: An alarming degree of SES inequality in oral health status was found in the studied community. Hence, it is suggested that inequalities in oral health status be reduced via adopting appropriate policies such as the delivery of oral health services to poorer groups and covering such services in insurance programs.