유치열에서 scissors bite의 치료에 대한 증례보고 : CASE REPORT

문성권,김정욱,이상훈,한세현,장기택 大韓小兒齒科學會 2006 大韓小兒齒科學會誌 Vol.33 No.2

중심교합위 상태에서 편측이나 양측으로 구치부의 상악치아가 하악치아의 협측으로 위치한 경우를 scissors bite라고 한다. 이런 부정교합은 상악의 폭이 크거나 하악의 폭이 좁은 경우 발생한다. 이로 인해 턱의 성장이 방해를 받고 악궁간 부조화를 유발하며 적절한 저작을 할 수 없게 된다. 따라서 scissor bite는 즉시 차단 교정을 해야 하며 일반적으로 scissors bite의 치료는 고정성 또는 가철성 장치를 이용하여 하악을 확장한다. 이에 저자는 scissors bite를 보이는 환아의 4세의 두명의 남아에게 Schwarz 장치를 이용하여 양호한 결과를 얻어 scissors bite의 치료법 제시에 도움이 되고자 보고하는 바이다. A scissors bite in the posterior teeth occurs when the upper teeth are positioned totally or unilaterally buccal to the lower teeth in centric occlusion. This malocclusion can result from either excessive width of maxilla, deficient width mandible, or combination of both. The malocclusion can lead to hindered growth of jaws or to asymmetry between the jaws. Besides, the severe lingual inclination of the mandibular posterior teeth prevents adequate mastication. Thus, the scissors bite is in need of immediate interceptive orthodontic interbention. The common treatments of the scissors bite is to expand the mandibular arch: fixed or removable appliances. In our clinic, we made a seccess in treatment of the scissors bite using the Schwarz appliance. We treated the scissors bite using the lower Schwarz appliance for a mean observation period of 21 months. The subjects were 2 boys, aged 4 years.

報漏閣 自擊漏 硏究(II) : 計時시스템

김성균,이재효,한영호,남문현 건국대학교 산업기술연구원 2006 건국기술연구논문지 Vol.31 No.-

This is the second part of the paper series about Jagyeungnoo, 'The Self Time Announcing Clepsydra', restoration project. The content of the second part is about the constant flow rate keeping system to the time measuring vessels. This system consists of three vessels. They are reservoir, compensating, and regulating vessels. In Jagyeungnoo system overflow mechanism was adopted to achieve constant flow rate regardless inflow rate variations. Through extensive parametric and experimental study based on extensive trial-error based on the mathematical model, optimal values of two parameters, i.e, initial height of regulating vessel and the diameter of the pipe exit orifice were determined and discussed improving method of accuracy. For the application of this result to Jagyeungnoo system, the eleven 24 solar seasonal time-ruler and its floating accessories were restored based upon Nujutongui, i.e. Clepsydra Operation Manual published in King Sejong's era.

ACTG2 Variants in Pediatric Chronic Intestinal Pseudo-obstruction With Megacystis

( Jong Woo Hahn ),( Soo Young Moon ),( Min Soo Kim ),( Min Hyung Woo ),( Min Ji Sohn ),( Hyun-young Kim ),( Moon-woo Seong ),( Sung Sup Park ),( Sung-hye Park ),( Jin Soo Moon ),( Jae Sung Ko ) 대한소화기기능성질환·운동학회 2022 Journal of Neurogastroenterology and Motility (JNM Vol.28 No.1

Background/Aims Chronic intestinal pseudo-obstruction (CIPO) is a clinically heterogeneous syndrome characterized by compromised peristalsis and intestinal obstruction. Variants of actin gamma 2 (ACTG2), a protein crucial for correct enteric muscle contraction, have been found in CIPO patients. The aim of this study is to examine the clinical features and ACTG2 variants in Korean patients with CIPO. Methods From January 1995 to August 2020, 12 patients diagnosed with CIPO were included and genetic analysis testing of ACTG2 was performed. Results Heterozygous ACTG2 missense variants were found in 6 patients (50.0%). The p.Arg257Cys variant was found in 3 patients, and p.Arg63Gln and p.Arg178His variants were found in 1 patient each. A novel variant, p.Ile193Phe, was found in 1 patient. Three patients were diagnosed at birth, 2 at the age of 1 year, and 1 at 3 years of age. Abnormal prenatal genitourinary ultrasonographic findings were found in all 6 patients; microcolon was found in 4 patients (66.7%), and megacystis in all 6 patients. The pathology showed abnormal ganglion cells as well as myopathic findings. All patients are dependent on total parenteral nutrition and are to date alive. Conclusions ACTG2 variants are commonly found in Korean patients with CIPO. In CIPO patients with megacystis and abnormal prenatal ultrasonography, genetic testing of ACTG2 should be considered. Molecular diagnosis of CIPO is more important than pathologic diagnosis. (J Neurogastroenterol Motil 2022;28:104-110)

脛骨下端部 骨髓炎의 數例 : 後方到達手術療法

韓文植,李鍾贊,劉相峯,李漢九 醫藥係社 1965 綜合 醫學 Vol.10 No.8

Volkmann雎血性拘縮에 對하여 : Report of 11 cases and Review of Literatures

文命相,林憲命,李甲淳,崔在鶴,韓文植 醫藥係社 1965 綜合 醫學 Vol.10 No.11

Use of Annular Closure Device (Barricaid®) for Preventing Lumbar Disc Reherniation: One-Year Results of Three Cases

Hahn, Bang Sang,Ji, Gyu Yeul,Moon, Bongju,Shin, Dong Ah,Ha, Yoon,Kim, Keung Nyun,Yoon, Do Heum Korean Neurotraumatology Society 2014 Korean Journal of Neurotrauma Vol.10 No.2

<P>Although lumbar discectomy is an effective treatment for lumbar disc herniation, complications exist, including postoperative disc height loss, facet joint degeneration, and recurrent disc herniation. To solve these problems, annular closure devices have been utilized in other countries, producing satisfactory results, but there has been no report of annular closure device use in our country. Here, we demonstrate the preliminary reports of Barricaid® insertion in 3 patients who underwent surgery for lumbar disc herniation.</P>

進行性, 化骨性 筋炎 : 症例報告 A Report of Two Cases

文命相,李甲淳,李德鏞,崔在鶴,韓文植 醫藥係社 1965 綜合 醫學 Vol.10 No.12

Vaccination and Complementary and Alternative Medicine in Patients with Inflammatory Bowel Disease

( Sung Bae Kim ),( Soo Jung Park ),( Sook Hee Chung ),( Kyu Yeon Hahn ),( Do Chang Moon ),( Sung Pil Hong ),( Jae Hee Cheon ),( Tae Il Kim ),( Won Ho Kim ) 대한장연구학회 2014 Intestinal Research Vol.12 No.2

Background/Aims: Vaccinations in patients with inflammatory bowel disease (IBD) are recommended to prevent infectiousdiseases. However, there are few reports of vaccination in IBD patients in Korea. The frequency of complementary and alternativemedicine (CAM) use is high despite its uncertain effectiveness. This study aimed to identify the rates of vaccination anduse of CAM in patients with IBD. Methods: A total of 219 patients attended an education session for IBD patients held at SeveranceHospital on March 23, 2013. We conducted a survey on vaccination and CAM use in IBD patients; 120 patients completedthe questionnaire. Results: The influenza vaccination rate was 44.2% and pneumococcal vaccination rate was 4.2%. Thirtyone(66%) patients were aware of the importance of vaccination. The vaccination rate was higher in patients who were awareof the importance of vaccination compared with that in patients who were unaware of the importance of vaccination (70.1%vs. 41.7%, P =0.004). The rate of CAM use was 30.0%. The most commonly used CAMs were oral products: vitamins (33.3%),red ginseng (25.0%), and probiotics (19.4%). Conclusions: Awareness of the importance of vaccination and actual vaccinationrates were low in IBD patients. Despite insufficient evidence on the effectiveness of CAMs in IBD patients, many patients usedCAMs. We believe that repeated education and promotion of vaccination are important. Further large-scale studies to investigatethe efficacy and safety of CAMs are warranted in patients with IBD. (Intest Res 2014;12:124-130)

THE EFFECT OF FLUORIDE VARNISH AND ACIDULATED PHOSPHATE FLUORIDE GEL ON ARTIFICIAL CARIES LESION : A MICROCOMPUTED TOMOGRAPHIC STUDY

Moon, Sung-Kwon,Lee, Jae-Cheoun,Kim, Young-Jae,Lee, Sang-Hoon,Hahn, Se-Hyun,Jang, Ki-Taeg 大韓小兒齒科學會 2004 大韓小兒齒科學會誌 Vol.31 No.2

치아 우식의 예방에 있어서 불소 도포는 효과적인 방법으로 재광화를 촉진하고 탈회를 억제한다. APF gel은 전문가 불소도포용으로 가장 일반적인 방법이었으나 최근 fluoride varnish가 소개되면서 그 사용이 증가되고 있다. 이번 연구의 목적은 fluoride varnish와 acidulated phosphate fluoride(APF gel)이 인공우식 병소에 미치는 영향을 시편의 화학적 고정이나 절단 없이 미세전산화 단층 촬영과 3차원 영상을 이용하여 재광화 효과를 비교해 보고자 함이다. 48개의 우식이 없는 건전한 영구 소구치에 인공우식을 유발하고 각 군당 16개씩, 세 군으로 나누었다. 1군은 대조군으로 어떠한 처치도 시행하지 않았다. 2군은 APF gel을 도포하고 1분 후에 gel을 거즈로 제거하여 수세하고 3군은 fluoride varnish를 도포한 후 45분 후에 얇은 varnish 막을 외과용 칼로 조심스럽게 제거하였다. 그 후 각 시편을 50㎖의 인공타액에 3개월 동안 담그어 둔 후 그 사이 기간동안 매달 미세전산화 단층 촬영을 이용하여 3차원 영상을 얻었다. 3차원 영상분석 프로그램으로 재광화 부위의 밀도를 측정하고 다음과 같은 결과를 얻었다. 1. 모든 군에서 시간이 지남에 따라 인공우식 부위의 밀도는 증가하였다. 2. APF gel 군과 fluoride varnish 군에서 한 달, 두 달, 세 달 후 밀도가 대조군보다 통계학적으로 유의성 있게 높았다(P<0.05). 3. APF gel 군과 fluoride varnish 군에서 처치전과 처치 한 달 후의 밀도 차이가 대주군보다 통계학적으로 유의성 있게 높았으며 fluoride varnish 군에서 처치 한 달 후와 처치 두 달 후의 밀도 차이가 대조군과 APF gel 군보다 유의성 있게 높았다(P<0.05). 4. Fluoride varnish가 APF gel보다 불소 처치 후 두 달, 세 달 후 재광화 효과가 더 우수하였고 오래 지속되었다. The application of acidulated phosphate fluoride gel(APF) and fluoride varnishes are the most common topical fluoride therapy. The purpose of this in vitro study was to compare the remineralization effects of two topical fluoride agents, APF gel and fluoride varnish with microtomograph and 3D image analyzer without sample preparation and chemical fixation. For the purpose of the study, the artificial caries lesion was caused on the caries-free permanent premolar and 48 specimens were divided into three groups each containing 16 specimens. No application was performed on group 1, which acted as control group. Group 2 was treated with APF gel and was removed after a minute. Group 3 was treated with the topical application of fluoride varnish and removed after 45 minutes. Each specimen was placed into a closed container with 50ml of a artificial saliva during three months and the 3D images of the remineralization area were taken using the SkyScan each month. Using the density-measuring program in V works^(TM), the density value of the remineralization area was measured. The following results were obtained: 1. All groups demonstrated an increase in the density of artificial caries lesion with time. 2. The density was significantly higher in APF gel and fluoride varnish group than control group at 1 month, 2 months, 3 months after the treatment(P(0.05). 3. The difference of the density between that "prior to treatment" and that "l month after treatment in Group 2 and Group 3 was significantly higher than that of Group 1 and, the difference of the density between that "1 month after treatment and that "2 month after treatment" in Group 3 was significantly higher than that of Group 1 and 2(P〈0.05). 4. The fluoride varnish was more effective after 2 and 3 months and continuous than the APF gel.

망간 노출 근로자의 정신 ·신경행동 양상에 영향을 주는 요인

문영한,권기련,김은아,김규상,김양호,김재우,노재훈,양정선,진영우 大韓産業醫學會 1999 대한직업환경의학회지 Vol.11 No.2

The risk posed to human health by environmental manganese (Mn) exposure is unknown. The purpose of this study is to establish if subclinical effects related to Mn exposure and examine the factors influencing psychoneurobehaviral outcomes of Mn exposed workers. This study involved 121 male workers of welding, alloy furnace, and manufacturing of welding stick. Study investigations include: a questionnaire covering demographic characteristics, job and exposure history and medical symptoms and conditions, monitoring workplace air for personal exposure to respirable and inhalable manganese, analysis of blood and urine samples, psychoneurobehaviral test(neurobehaviral core test battery(NCTB), signal change on magnetic resonance imaging (MRI) scans, minimental state and neurological examination). The main results of this study were as follows; 1. Preliminary results showed that, with increasing manganese exposure, neurobehaviral performance was poorer and signal change on MRI scans increased. 2. The results of examination revealed significant relations on psychoneurobehaviral outcomes (neurobehaviral performance, signal change on MRI scans, and neurological features). 3. In multiple regression, age and educational status as demographic variables and exposure level were significantly related to neurobehaviral test. Also exposure level and serum Mn concentrations were positively related to signal change on MRI scans and neurological features affected by Mn on the brain (signal change). 4. Psychoneurobehaviral outcomes from Mn exposure were related to neurobehaviral performance, signal change on MRI scans, neurological features and profile of mood states (POMS), and influenced positively with age, alcohol and smoking history, and duration of Mn exposure, negatively with educational status. Serum Mn concentrations in combination with brain MRI scans, and perhaps a battery of neurobehaviral tests, appear to be the best way to monitor excessive exposure to Mn. These results are consistent with our knowledge on Mn action on the brain and are similar to the type of neurobehaviral dysfunction. They suggest that there may be age, educational status, and life style (alcohol and drinking history) differences with chronic environmental exposure. These findings suggest further evaluation, particularly on relationships between Mn exposure, aging, and susceptibility factors.