Effects of Vocabulary Size on Anticipatory Sentence Processing in Korean Learners of English

Yuree Noh,Miseon Lee 한국언어학회 2016 언어 Vol.41 No.3

Noh Yuree & Lee Miseon. 2016. Effects of vocabulary size on anticipatory sentence processing in Korean learners of English. Korean Journal of Linguistics, 41-3. 359-378. The present study investigates whether and the extent to which nonnative speakers of English exhibit anticipatory processing of English sentences in comparison to native speakers (Borovsky et al., 2012), using a looking-while-listening paradigm. We also examine the relationship between the anticipatory behavior and vocabulary knowledge of English as a second language. College students with high-intermediate English proficiency participated in an eye-tracking experiment and an offline measurement of vocabulary knowledge. The results revealed that the participants anticipate upcoming words, thereby incrementally processing English sentences as native speakers do. In doing so, they also actively make use of combinatory information of semantic cues and real-world knowledge, having advantage of a larger L2 vocabulary size. (Hanyang University)

Survival impact of low anterior resection in the patients with epithelial ovarian cancer grossly confined to pelvic cavity: A multicenter retrospective study

( Miseon Kim ),( Jeong-yeol Park ),( E Sun Baik ),( Hee Seung Kim ),( Sunghoon Kim ),( Dong Hoon Suh ) 대한산부인과학회 2016 대한산부인과학회 학술대회 Vol.102 No.-

목적: To evaluate the survival impact of low anterior resection (LAR) in patients with epithelial ovarian cancer (EOC) grossly confined to pelvis. 방법: A total of 397 patients who underwent primary staging operation for the treatment of stage II-IIIA EOC was retrospectively reviewed: 116 (29.2%) IIA, 212 (53.4%) IIB, 30 (7.6%) IIIA1, and 39 (9.8%) IIIA2. Patients who had grossly enlarged retroperitoneal lymph nodes positive for metastatic carcinoma were excluded. Total study population comprised three groups according to the presence of gross tumor on intrapelvic rectosigmoid colon and bowel resection: no-tumor/non-LAR group (n=305, 76.8%), tumor/non-LAR group (n=68, 17.1%), and tumor/LAR group (n=24, 6.1%). Survival rates were compared between the groups. 결과: Median follow-up was 36 months (range 0-260 months). Five-year progression-free survival (PFS) of stage IIA, IIB, IIIA1, and IIIA2 were 65.1%, 61.0%, 50.4%, and 45.5%, respectively. There was no survival difference between no-tumor (n=305) and tumor (n=92) groups. All patients of tumor/non-LAR group underwent tumorectomy and/or electrocoagulation. Survival difference was not observed between no-tumor/non-LAR group and tumor/non-LAR group (5-yr PFS, 60.4% vs.58.3%; p=0.530 and 5-yr overall survival [OS], 81.2% vs. 88.0%; p=0.985) even though complete cytoreduction rate was significantly higher in no-tumor/non-LAR group than tumor/non-LAR group (p<0.001). There was no significant survival difference between tumor/LAR and tumor/non-LAR groups (5-yr PFS, 62.5% vs. 58.3%; p=0.787 and 5-yr OS, 63.5% vs. 88.0%; p=0.078). Age, histologic type, optimal cytoreduction rate (residual tumor size≤1cm), and cycle number of adjuvant chemotherapy were not different between the groups of comparisons. Postoperative ileus ≥grade 2 was more frequently observed in LAR group than non-LAR group (13.6% vs. 3.2%; p=0.013). 결론: Survival benefit of LAR does not appear to be significant in the patients with grossly pelvis-confined EOC where post-tumorectomy site on intrapelvic rectosigmoid colon might not be considered as residual tumor.

Franco Fabbro, The Neurolinguistics of Bilingualism : An Introduction

Miseon Lee(서평자) 한국응용언어학회 2004 응용 언어학 Vol.20 No.2

Effect of polysaccharides from a Korean ginseng berry on the immunosenescence of aged mice

Miseon Kim,이영수,김주원,Sang Yun Han,Su Hwan Kim,Dae Bang Seo,Jae Youl Cho,신송석 고려인삼학회 2018 Journal of Ginseng Research Vol.42 No.4

Background: Korean ginseng has been widely evaluated to treat human diseases; however, most studies on Korean ginseng have focused on its root. In this study, polysaccharides [acidic-polysaccharide-linked glycopeptide (APGP) extracted with 90% ethanol and hot water] were prepared from Korean ginseng berries, and their effect on immunosenescence was explored. Methods: The effect of APGP on thymic involution was evaluated by measuring the size of thymi dissected from aged mice. The effect of APGP on populations of immune cells, including natural killer (NK) cells, dendritic cells, age-correlated CD11c-positive B cells, and several subtypes of T cells [CD4- positive, CD8-positive, and regulatory (Treg) T cells] in the thymi and spleens of aged mice was analyzed by fluorescence-activated cell sorting analysis. Serum levels of interleukin (IL)-2 and IL-6 were evaluated by enzyme-linked immunosorbent assay analysis. Profiles of APGP components were evaluated by high-performance liquid chromatography (HPLC) analysis. Results: APGP suppressed thymic involution by increasing the weight and areas of thymi in aged mice. APGP increased the population of NK cells, but showed no effect on the population of dendritic cells in the thymi and spleens of aged mice. APGP decreased the population of age-correlated CD11c-positive B cells in the spleens of aged mice. APGP showed no effect on the populations of CD4- and CD8-positive T cells in the thymi of aged mice, whereas it increased the population of Treg cells in the spleens of aged mice. APGP further decreased the reduced serum levels of IL-2 in aged mice, but serum levels of IL-6 were not statistically changed by APGP in aged mice. Finally, HPLC analysis showed that APGP had one major peak at 15 min (a main type of polysaccharide) and a long tail up to 35 min (a mixture of a variety of types of polysaccharides). Conclusion: These results suggested that APGP exerted an anti-immunosenescent effect by suppressing thymic involution and modulating several types of immune cells.

Bilateral salpingectomy to reduce the risk of ovarian/ fallopian/peritoneal cancer in women at average risk: a position statement of the Korean Society of Obstetrics and Gynecology (KSOG)

( Miseon Kim ),( Young-han Kim ),( Yong Beom Kim ),( Jayeon Kim ),( Jae-weon Kim ),( Mi Hye Park ),( Joo Hyun Park ),( Jeong Ho Rhee ),( Myong Cheol Lim ),( Joon-seok Hong ) 대한산부인과학회 2018 Obstetrics & Gynecology Science Vol.61 No.5

Based on the current understanding of a preventive effect of bilateral salpingectomy on ovarian/fallopian/peritoneal cancers, the Korean Society of Obstetrics and Gynecology, Korean Society of Gynecologic Endocrinology, Korean Society of Gynecologic Oncology, Korean Society of Maternal Fetal Medicine, and Korean Society for Reproductive Medicine support the following recommendations: · Women scheduled for hysterectomy for benign gynecologic disease should be informed that bilateral salpingectomy reduces the risk of ovarian/fallopian/peritoneal cancer, and they should be counseled regarding this procedure at the time of hysterectomy. · Although salpingectomy is generally considered as a safe procedure in terms of preserving ovarian reserve, there is a lack of evidences representing its long-term outcomes. Therefore, patients should be informed about the minimal potential of this procedure for decreasing ovarian reserve. · Prophylactic salpingectomy during vaginal hysterectomy is favorable in terms of prevention of ovarian/fallopian/ peritoneal cancer, although operation-related complications minimally increase with this procedure, compared to the complications associated with vaginal hysterectomy alone. Conversion to open or laparoscopic approach from vaginal approach to perform prophylactic salpingectomy is not recommended. · Women who desire permanent sterilization at the time of cesarean delivery could be counseled for prophylactic salpingectomy before surgery on an individual basis.

Estrogen Regulates the Expression of Aminoacyl-tRNA-Synthetase-Interacting Multifunctional Protein-1 (Aimp1) in the Mouse Uterus

Miseon Park,Eun Jin Lim,Si-jeong Bea,Eunhye Kim,Young-eun Lee,Dong Ryul Lee,Youngsok Choi 한국동물생명공학회(구 한국동물번식학회) 2014 한국동물번식학회 한중일 심포지엄 Vol.2014 No.1

Aimp1 is known as a multifunctional cytokine in various cellular events. Recent study showed Aimp1 is localized in glandular epithelial, endothelial, and stromal cells in functionalis and basalis layers of the endometrium. However, the regulatory mechanism of Aimp1 in the uterus remains unknown. In the present study, we found that Aimp1 is expressed in the mouse uterus. Aimp1 transcripts were decreased at diestrus stage. However, the level of Aimp1 protein was significantly increased in the luminal epithelium in the uterine endometrium at the estrus stage during the estrous cycle. In addition, we found that the treatment of estrogen increased the expression of Aimp1 in the uterus. The treatment of estrogen increased Aimp1 expression in the uterus of ovarectomized mice. We identified one estrogen receptor binding element (ERE) on the mouse Aimp1 promoter. The activity of Aimp1 promoter was increased with estrogen treatment. Our findings indicate that Aimp1 might act as an important regulator to remodel the uterine endometrium and its expression might be regulated by estrogen during the estrous cycle. This will give us better understanding the dynamic change of uterine remodeling during the estrous cycle.

Bit Flip Reduction Schemes to Improve PCM Lifetime

Miseon Han,Youngsun Han 대한전자공학회 2016 IEIE Transactions on Smart Processing & Computing Vol.5 No.5

Recently, as the number of cores in computer systems has increased, the need for larger memory capacity has also increased. Unfortunately, dynamic random access memory (DRAM), popularly used as main memory for decades, now faces a scalability limitation. Phase change memory (PCM) is considered one of the strong alternatives to DRAM due to its advantages, such as high scalability, non-volatility, low idle power, and so on. However, since PCM suffers from short write endurance, direct use of PCM in main memory incurs a significant problem due to its short lifetime. To solve the lifetime limitation, many studies have focused on reducing the number of bit flips per write request. In this paper, we describe the PCM operating principles in detail and explore various bit flip reduction schemes. Also, we compare their performance in terms of bit reduction rate and lifetime improvement.

Transcriptional Response and Enhanced Intestinal Adhesion Ability of Lactobacillus rhamnosus GG after Acid Stress

( Miseon Bang ),( Cheng-chung Yong ),( Hyeok-jin Ko ),( In-geol Choi ),( Sejong Oh ) 한국미생물생명공학회(구 한국산업미생물학회) 2018 Journal of microbiology and biotechnology Vol.28 No.10

Lactobacillus rhamnosus GG (LGG) is a probiotic commonly used in fermented dairy products. In this study, RNA-sequencing was performed to unravel the effects of acid stress on LGG. The transcriptomic data revealed that the exposure of LGG to acid at pH 4.5 (resembling the final pH of fermented dairy products) for 1 h or 24 h provoked a stringent-type transcriptomic response wherein stress response- and glycolysis-related genes were upregulated, whereas genes involved in gluconeogenesis, amino acid metabolism, and nucleotide metabolism were suppressed. Notably, the pilus-specific adhesion genes, spaC, and spaF were significantly upregulated upon exposure to acid-stress. The transcriptomic results were further confirmed via quantitative polymerase chain reaction analysis. Moreover, acid-stressed LGG demonstrated an enhanced mucin-binding ability in vitro, with 1 log more LGG cells (p < 0.05) bound to a mucin layer in a 96-well culture plate as compared to the control. The enhanced intestinal binding ability of acid-stressed LGG was confirmed in an animal study, wherein significantly more viable LGG cells (≥ 2 log CFU/g) were observed in the ileum, caecum, and colon of acid-stressed LGG-treated mice as compared with a non-acid-stressed LGG-treated control group. To our knowledge, this is the first report showing that acid stress enhanced the intestine-binding ability of LGG through the induction of pili-related genes.

The Practice of English Writing Assessment in Korean High Schools

Miseon Lee 한국영어교육학회 2019 KATE Forum Vol.43 No.1

Development and Evaluation of Autonomy Support Program using Mobile for Prevention of Metabolic Syndrome in Middle-Aged Women

Miseon Seo,Eun-Young Jun 한국간호과학회 2021 한국간호과학회 학술대회 Vol.2021 No.10

Aim(s): This study was to examine effects of the autonomy support program using mobile on basic psychological needs, autonomous motivation, health behavior, and metabolic syndrome indicator in middle-aged women. Method(s): A quasi-experimental pretest and posttest design was used. A total of 47 participants (experimental 24, control 23) were middle age women who had one or two symptoms of 5 risk factors of metabolic syndrome, which are waist circumference, blood pressure, triglyceride, high density cholesterol, and fasting blood glucose. Autonomy support program using mobile was main strategies of the program being self-selection, proper goal settings and motivation, improving sense of ability, providing information for clear evidence presentation, perceiving internal conflict, providing positive feedback and emotional recognition of subjects. The program effects were measured by basic psychological needs (autonomy, competence, and relatedness), autonomous motivation, health behavior, and metabolic syndrome indicator. The collected data were analyzed using descriptive statistics, chi-square test, t-test, and paired t-test. Result(s): There were significant differences in autonomy, competence, autonomous motivation, health behavior, circumference, and systolic blood pressure between the experimental and control groups. Relatedness, diastolic blood pressure, triglyceride, high density cholesterol, and fasting blood glucose improved in the experimental group compared to the control group, but the differences were not significant. Conclusion(s): The autonomy support program provides the health care system for middle-aged women with accessibility to the local community and cost effective strategy. Therefore, we expect that the program will be utilized as the nursing intervention in all aspects of nursing practice.