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( Nobuyasu Awano ),( Minoru Inomata ),( Naoyuki Kuse ),( Mari Tone ),( Hanako Yoshimura ),( Tatsunori Jo ),( Kohei Takada ),( Chikatoshi Sugimoto ),( Tomonori Tanaka ),( Hiromitsu Sumikawa ),( Yuzo Su 대한결핵 및 호흡기학회 2019 대한결핵 및 호흡기학회 추계학술대회 초록집 Vol.127 No.-
Background: Idiopathic pulmonary fibrosis (IPF) is a progressive disease often accompanied by skeletal muscle wasting. We aimed to assess whether skeletal muscle mass and muscle attenuation on computed tomography (CT) are predictors of mortality in IPF patients using a nationwide cloud-based database and web-based multidisciplinary discussion (MDD) system. Methods: IPF patients diagnosed using MDD from April 2009 to March 2014 were included. We analyzed the cross-sectional area (CSA) of the erector spinae muscle (ESM<sub>CSA</sub>) and the pectoralis muscle (PM<sub>CSA</sub>), muscle attenuation of ESM (ESM<sub>MA</sub>), and PM (PM<sub>MA</sub>) on single-slice axial CT. Survival probability was assessed by the Kaplan-Meier method and compared by the log-rank test. Multivariate Cox proportional hazards models were performed to evaluate the relationship among the ESM<sub>CSA</sub>, PM<sub>CSA</sub>, ESM<sub>MA</sub>, PM<sub>MA</sub>, clinical parameters, and prognosis. Results: A total of 199 IPF patients were enrolled. Seventy-four patients died during the study period and the most frequent cause was acute exacerbation (13.1%). The group with the lowest quartile of ESMCSA had significantly worse survival than other groups (P = 0.009). Survival rates of the groups with the lowest quartile of PM<sub>CSA</sub>, lower ESM<sub>MA</sub>, and lower PM<sub>MA</sub> were not different from other groups. After multivariate analysis, ESM<sub>CSA</sub> < lower quartile was significantly associated with all-cause mortality (hazards ratio, 1.96; P = 0.030), whereas, ESM<sub>MA</sub> < median, PM<sub>CSA</sub> < lower quartile, and PM<sub>MA</sub> < median were not. Conclusions: Low ESM<sub>CSA</sub> on CT images may be a strong risk factor for all-cause mortality in IPF patients nationwide by MDD diagnosis.
A Proposal of Refactoring toWell-StructuredWorkflow Nets
Yuki Kuroda,Shingo Yamaguchi,Minoru Tanaka 대한전자공학회 2009 ITC-CSCC :International Technical Conference on Ci Vol.2009 No.7
In this paper, we discuss refactoring free choice workflow nets (WF-net for short) to well-structured ones. It is known that most actual workflows can be modeled as free choice or well-strcutured WF-nets. There are more analysis methods for well-structured WF-nets. Refactoring free choice WF-nets to well-structured ones enables us to apply many analysis methods to free choice ones. We propose two rules for the refactoring. And we show an example of refactroing a WF-net, which represents the actual workflow for an travel agency.
Two Step Framework to Extend Workflow Nets and Soundizability Problem
Shingo Yamaguchi,Ryo Ikeda,Minoru Tanaka 대한전자공학회 2009 ITC-CSCC :International Technical Conference on Ci Vol.2009 No.7
We discuss in this paper whether we can extend work-flow nets (WF-nets for short) under the condition to preserve behavioral inheritance and soundness. We propose a two step framework to extend WF-nets, i.e. we first extend a given WF-net under the condition to preserve only behavioral inheritance, and then correct it to be sound if necessary. We tackle a problem of deciding whether we can correct an unsound WF-net to be sound under the condition to preserve behavioral inheritance, named soundizability problem. There are two kinds of behavioral inheritance: Projection inheritance and protocol inheritance. Our results show that if an acyclic free choice WF-net is extended under the condition to preserve projection inheritance, the extended WF-net is sound; If an acyclic free choice WF-net is extended under the condition to preserve protocol inheritance, the extended WF-net may be unsound; The unsound extended WF-net cannot be corrected to be sound under the condition to preserve projection inheritance, but may be corrected under the condition to preserve protocol inheritance.