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      • KCI등재

        A Study of the Content Validity of Reading Comprehension Tests in NMET II

        Zhen-Jie Liu,Ming-Hao Jin 대한언어학회 2018 언어학 Vol.26 No.4

        Liu, Zhen-Jie & Jin, Ming-Hao. (2018). A study of the content validity of reading comprehension tests in NMET II. The Linguistic Association of Korea Journal, 26(4), 103-124. Based on Bachman and Palmer’s (1996) framework of task characteristics, this paper aims to compare the reading comprehension tests of the 2013-2017 National Matriculation English Test II (NMET II) with the requirements of the New Curriculum Standards and Testing Syllabus, in particular, concerning the content validity of the tests in terms of the characteristics of input and expected responses. The implications of this study are discussed for test designers, teachers, and students. The results show that reading comprehension tests from 2013 to 2017 basically meet the requirements of the New Curriculum Standard and Testing Syllabus and have a high content validity. In terms of the characteristics of input, the length, reading speed, and readability of comprehension passages are appropriate for students; however, the distribution of topics and genres in each year is uneven. In terms of the characteristics of expected responses, the wordings of questions and the design of question items are reasonable. However, the response type is mainly restricted to selected response questions (multiple-choice), and the measure of reading skills coverage is unbalanced.

      • 뇌졸중환자의 인지기능에 관한 연구

        류명인,소희영 충남대학교 간호과학연구소 2006 충남대 간호학술지 Vol.9 No.1

        Purpose: This study was to explore the cognitive function of stroke patients. Method: The study sample were 88 who were possible to communicate and agreed to participate. The data was collected at OPD and wards from 2 Veteran's hospital located at Daejeon and Seoul and one C University hospital by trained nursing students at 2004 February. this research design is survey research. The measurement tool was MMSE-K. The data were analysed by SPSS 10.0 using frequency, t-test ANOVA, Pearson's correlation coefficients and Regression. Result: The mean score of MMSE-K was 26.74, being from minimum 13 to maximum 30. There was significant difference in attention/calculation subtype of MMSE-K according to length of education. There were statistically significant correlation among Time orientation, Place orientation, Registration, Attention & Calculation, Recall and Language. Conclusion: The cognitive function score of stroke patients was within normal limit. The length of education was a significant demographic characteristic affecting cognitive function. For rehabilitative care of stroke patient, the nurse has to collect data about cognition as well as demographic characteristics like income and perceived health status in order tar understand better and improve patients cognitive function.

      • Low Expression of the FoxO4 Gene may Contribute to the Phenomenon of EMT in Non-small Cell Lung Cancer

        Xu, Ming-Ming,Mao, Guo-Xin,Liu, Jian,Li, Jian-Chao,Huang, Hua,Liu, Yi-Fei,Liu, Jun-Hua Asian Pacific Journal of Cancer Prevention 2014 Asian Pacific journal of cancer prevention Vol.15 No.9

        Because of its importance in tumor invasion and metastasis, the epithelial-mesenchymal transition (EMT) has become a research focus in the field of cancer. Recently, evidence has been presented that FoxO4 might be involved in EMT. Our study aimed to detect the expression of FoxO4, E-cadherin and vimentin in non-small cell lung cancers (NSCLCs). We also investigated clinical features and their correlations with the markers. In our study, FoxO4, E-cadherin and vimentin were assessed by immunohistochemistry in a tissue microarray (TMA) containing 150 cases of NSCLC. In addition, the expression level of FoxO4 protein was determined by Western blotting. The percentages of FoxO4, E-cadherin and vimentin positive expression in NSCLCs were 42.7%, 38.7% and 55.3%, respectively. Immunoreactivity of FoxO4 was low in NSCLC when compared with paired normal lung tissues. There were significant correlations between FoxO4 and TNM stage (P<0.001), histological differentiation (P=0.004) and lymph node metastasis (P<0.001), but no significant links with age (P=0.323), gender (P=0.410), tumor size (P=0.084), smoking status (P=0.721) and histological type (P=0.281). Our study showed that low expression of FoxO4 correlated with decreased expression of E-cadherin and elevated expression of vimentin. Cox regression analysis indicated FoxO4 to be an independent prognostic factor in NSCLC (P=0.046). These data suggested that FoxO4 might inhibit the process of EMT in NSCLC, and might therefore be a target for therapy.

      • Design of 3-electrode system for <i>in situ</i> monitoring direct methanol fuel cells during long-time running test at high temperature

        Liu, Guicheng,Li, Xinyang,Wang, Hui,Liu, Xiuying,Chen, Ming,Woo, Jae Young,Kim, Ji Young,Wang, Xindong,Lee, Joong Kee Elsevier 2017 APPLIED ENERGY Vol.197 No.-

        <P>To understand the effect mechanisms of long-time running and high operation temperature on performance of the direct methanol fuel cell (DMFC) more clearly and directly, in this paper, a new design of 3-electrode system with a solution-type salt bridge has been developed to distinguish the integral polarization into anodic and cathodic polarizations at various temperatures and explore the attenuation mechanism by in situ monitoring the potential of anode during long-time running process at 80 degrees C, for the first time. The results indicate that the optimized 3-electrode system consists of a standard calomel electrode (SCE) and a solution-type salt bridge placed in the anode hole filled by 0.5 mol L-1 H2SO4 solution. By utilization of the 3-electrode system, the effect mechanisms of the running temperature and time on electrochemical parameters of the DMFC have been found: (1) The increasing operation temperature improves cathodic performance more significantly than that of anode; (2) the attenuation of fuel cell performance mainly comes from that of anode during the 20-h running test at 80 degrees C, resulting from the sharp drop of electrochemical active surface area of anode. More important, the new 3-electrode system has simplified the detection equipment and reduced the operating difficulty in a practical application for DMFCs, resulting in its portability. (C) 2017 Elsevier Ltd. All rights reserved.</P>

      • SCIESCOPUSKCI등재

        Modification of DC Flashover Voltage at High Altitude on the Basis of Molecular Gas Dynamics

        Liu, Dong-Ming,Guo, Fu-Sheng,Sima, Wen-Xia The Korean Institute of Electrical Engineers 2015 Journal of Electrical Engineering & Technology Vol.10 No.2

        The effect of altitude on thermal conduction, surface temperature, and thermal radiation of partial arc was investigated on the basis of molecular gas dynamics to facilitate a deep understanding of the pollution surface discharge mechanism. The DC flashover model was consequently modified at high altitude. The validity of the modified DC flashover model proposed in this paper was proven through a comparison with the results of high-altitude simulation experiments and earlier models. Moreover, the modified model was found to be better than the earlier modified models in terms of forecasting the flashover voltage. Findings indicated that both the thermal conduction coefficient and the surface thermodynamics temperature of partial arc had a linear decrease tendency with the altitude increasing from 0 m to 3000 m, both of which dropped by approximately 30% and 3.6%, respectively. Meanwhile, the heat conduction and the heat radiation of partial arc both had a similar linear decrease of approximately 15%. The maximum error of DC pollution flashover voltage between the calculation value according to the modified model and the experimental value was within 6.6%, and the pollution flashover voltage exhibited a parabola downtrend with increasing of pollution.

      • KCI등재

        Sputum Metabolomic Profiling Reveals Metabolic Pathways and Signatures Associated With Inflammatory Phenotypes in Patients With Asthma

        Liu Ying,Zhang Xin,Zhang Li,Oliver Brian G,Wang Hong Guang,Liu Zhi Peng,Chen Zhi Hong,Wood Lisa,Hsu Alan Chen-Yu,Xie Min,McDonald Vanessa,Wan Hua Jing,Luo Feng Ming,Liu Dan,Li Wei Min,Wang Gang 대한천식알레르기학회 2022 Allergy, Asthma & Immunology Research Vol.14 No.4

        Purpose: The molecular links between metabolism and inflammation that drive different inflammatory phenotypes in asthma are poorly understood. We aimed to identify the metabolic signatures and underlying molecular pathways of different inflammatory asthma phenotypes. Methods: In the discovery set (n = 119), untargeted ultra-high-performance liquid chromatography-mass spectrometry (UHPLC-MS) was applied to characterize the induced sputum metabolic profiles of asthmatic patients with different inflammatory phenotypes using orthogonal partial least-squares discriminant analysis (OPLS-DA), and pathway topology enrichment analysis. In the validation set (n = 114), differential metabolites were selected to perform targeted quantification. Correlations between targeted metabolites and clinical indices in asthmatic patients were analyzed. Logistic and negative binomial regression models were established to assess the association between metabolites and severe asthma exacerbations. Results: Seventy-seven differential metabolites were identified in the discovery set. Pathway topology analysis uncovered that histidine metabolism, glycerophospholipid metabolism, nicotinate and nicotinamide metabolism, linoleic acid metabolism as well as phenylalanine, tyrosine and tryptophan biosynthesis were involved in the pathogenesis of different asthma phenotypes. In the validation set, 24 targeted quantification metabolites were significantly expressed between asthma inflammatory phenotypes. Finally, adenosine 5′-monophosphate (adjusted relative risk [adj RR] = 1.000; 95% confidence interval [CI] = 1.000–1.000; P = 0.050), allantoin (adj RR = 1.000; 95% CI = 1.000–1.000; P = 0.043) and nicotinamide (adj RR = 1.001; 95% CI = 1.000–1.002; P = 0.021) were demonstrated to predict severe asthma exacerbation rates. Conclusions: Different inflammatory asthma phenotypes have specific metabolic profiles in induced sputum. The potential metabolic signatures may identify therapeutic targets in different inflammatory asthma phenotypes.

      • KCI등재

        A new power supply strategy for high power rectifying units in electrolytic copper process

        Liu He-Miao,Zhao Yu-Lian,Cheng Yan-Ming,Wu Jing,Al Shurafa Mahmoud A. M.,Liu Cheng,Lee Il-Kyoo 대한전기학회 2022 Journal of Electrical Engineering & Technology Vol.17 No.2

        For achieving the minimum energy consumption in electrolytic copper process, this paper proposes a power supply optimization strategy based on the improved BP neural network for high-power electrolytic copper rectifying units to eff ectively improve the utilization rate of electric energy, reduce the production cost, and achieve high effi ciency and energy saving. Aiming to operation scenarios including normal operation of rectifi ers, fault of random one rectifi er, fault of random two rectifi ers and number change of electrolytic tanks, the output current of each rectifi er, transformer gears and control angle of thyristor are obtained under these four scenarios by the proposed power supply strategy. The simulation results indicate that compared with BP neural network and PSO optimizing BP(PSO-BP)neural network, the prediction error of power supply strategy of GA optimizing BP (GA-BP) neural network is the minimum. Consequently, the optimal control of the output current of each rectifi er is obtained by using GA-BP neural network, and the stabilized current precision of total output current can be kept at 0.003–0.005, which verifi es the eff ectivity and feasibility of the proposed power supply optimization strategy, which provides valuable guidance and reference for the future design of high-power power supply system in electrolytic copper or other electrolytic metals.

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