Effects of Two Types of Indirect Written Corrective Feedback on the Acquisition of English Articles

Mijeong Song,Given Lee 한국외국어교육학회 2017 Foreign languages education Vol.24 No.3

The study investigates the relative effects of two types of indirect written corrective feedback (CF) on the acquisition of English articles. Thirty-five high intermediate Korean EFL college students who were enrolled in three composition classes participated in this study. After the instruction on the English article usage, three classes (Class A, Class B, and Class C) received different types of feedback on their blog writings over the course of a semester. Both Class A and Class B received indirect feedback in the form of underlining errors. In the following class, Class A received correct forms with metalinguistic information for the errors revised incorrectly, but Class B did not have such opportunities. The Class C received no feedback. The results showed that only Class A, which received indirect feedback plus correct forms with metalinguistic information, made a statistically significant gain from the 3 sessions of feedback treatment. Pedagogical implications were provided on the basis of the findings.

텃밭 가꾸기 활동이 유아의 행복감과 사회·정서능력에 미치는 영향

송미정(Song, mijeong),유영의(Yoo, yungeui) 학습자중심교과교육학회 2018 학습자중심교과교육연구 Vol.18 No.12

본 연구는 텃밭 가꾸기 활동이 유아의 행복감과 사회 정서능력 발달에 긍정적인 효과가 있는지를 검증하는 것을 목적으로 한다. 이러한 연구목적을 위하여 본 연구에서의 연구대상은 충남에 위치한 A유치원의 만 5세 20명을 실험집단으로, B유치원의 만 5세 20명을 비교집단으로 선정하였다. 연구도구는 유아 행복 척도와 사회ㆍ정서 능력 발달 척도를 사용하였으며, 연구는 예비연구, 평정자교육실시, 사전검사, 실험처지, 사후검사의 순으로 진행하였다. 텃밭가꾸기 활동은 총 8주간, 16회 실시되었으며, 자료 분석은 SPSS 18.0 통계 프로그램을 이용하여 실험집단과 비교집단 유아들의 사전, 사후 평균과 표준편차를 구하고 공분산분석을 하였다. 연구결과는 첫째, 텃밭 가꾸기 활동은 유아의 행복감을 증진시키는데 효과적이었고, 행복감의 하위요소 중에서 ‘생활만족’을 제외한 ‘몰입’, ‘건강’, ‘심미감’, ‘또래관계’, ‘교사관계’, ‘인지 및 성취’, ‘정서’, ‘부모관계’ 의 8가지 요소에서 활동 전에 비하여 활 동 후에 증가하는 것으로 나타났다. 둘째, 텃밭 가꾸기 활동은 유아의 사회 정서능력 발달을 증진시키는데 효과가 있는 것으로 나타났다. 그리고 사회정서능력발달의 하위 요소인 ‘교사에 대한 비의존성’, ‘내적통제’, ‘또래와의 상호작용’, ‘유치원에서의 안정감’, ‘성취동기’, ‘호기심’ 모두에서 활동전보다 활동 후에 증가하는 것으로 나타났다. The objective of this study was to investigate the effects of garden activities on children s happiness and social-emotional development. Among two selected kindergarten in C city, we assigned one to an experimental group and the other to a control group. Twenty children in the experimental group participated in gardening activity 16 times for 8 weeks while another 20 children in the control group did outdoor play based on the Nuri curriculum. The results of this study were summarized as follows. First, there were statistically significant differences in eight elements, immersion , health , esthetics , peer relationship , teacher relationship , awareness and achievement , emotion , and parent relationship except for living satisfaction Second, there were statistically significant differences in all of the six subordinate elements in social and emotional capabilities, independency for teachers , internal control , mutual interaction between peers , stability in an institution , achievement motivation , and curiosity

Perilla Oil Suppresses Lipid Accumulation in the Liver via Suppression of Fatty Acid Synthase (FAS) and 3-hydroxylglutaryl-CoA reductase (HMGCR) in Apo E KO Mice Fed High Cholesterol Diet

Mijeong Kim,Yeong-Ok Song 한국식품영양과학회 2012 한국식품영양과학회 학술대회발표집 Vol.2012 No.10

Plasma Lipid Lowering Effects of Bugak, Traditional Korean Fried Food

Mijeong Kim,Sun Hee Hong,Lana Chung,Jeong-Eun Yang,Eunok Choe,Yeong Ok Song 한국식품영양과학회 2013 한국식품영양과학회 학술대회발표집 Vol.2013 No.11

HIF1A overexpression using cell-penetrating DNA-binding protein induces angiogenesis in vitro and in vivo

Jeon, Mijeong,Shin, Yooseok,Jung, Jaeeun,Jung, Ui-Won,Lee, Jae-Hoon,Moon, Jae-Seung,Kim, Ilkoo,Shin, Jin-Su,Lee, Sang-Kyou,Song, Je Seon Springer-Verlag 2018 MOLECULAR AND CELLULAR BIOCHEMISTRY - Vol.437 No.1

<P>Hypoxia-inducible factor-1 alpha (HIF1A) is an important transcription factor for angiogenesis. Recent studies have used the protein transduction domain (PTD) to deliver genes, but the PTD has not been used to induce the expression of HIF1A. This study aimed at using a novel PTD (Hph-1-GAL4; ARVRRRGPRR) to overexpress the HIF1A and identify the effects on angiogenesis in vitro and in vivo. Overexpression of HIF1A was induced using Hph-1-GAL4 in human umbilical vein/vascular endothelium cells (HUVEC). The expression levels of genes were analyzed by the quantitative real-time polymerase chain reaction (qPCR) after 2 and 4 days, respectively. An in vitro tube formation was performed using Diff-Quik staining. HIF1A and Hph-1-GAL4 were injected subcutaneously into the ventral area of each 5-week-old mouse. All of the plugs were retrieved after 1 week, and the gene expression levels were evaluated by qPCR. Each Matrigel plug was evaluated using the hemoglobin assay and hematoxylin and eosin (HE) staining. The expression levels of HIF1A and HIF1A target genes were significantly higher in HIF1A-transfected HUVEC than in control HUVEC in vitro. In the in vivo Matrigel plug assay, the amount of hemoglobin was significantly higher in the HIF1A-treatment group than in the PBS-treatment group. Blood vessels were identified in the HIF1A-treatment group. The expression levels of HIF1A, vascular endothelial growth factor (Vegf), and Cd31 were significantly higher in the HIF1A-treatment group than in the PBS-treatment group. These findings suggest that using Hph-1-G4D to overexpress HIF1A might be useful for transferring genes and regenerating tissues.</P>

백년초 및 녹차 가루 첨가 연근 부각의 지질저하 기능성

김미정(Mijeong Kim),홍선희(Sun Hee Hong),정라나(Lana Chung),최은옥(Eunok Choe),송영옥(Yeong-Ok Song) 한국식품영양과학회 2014 한국식품영양과학회지 Vol.43 No.3

본 연구는 한국 전통부각 제조방법을 이용하여 부각을 부식으로뿐만 아니라 스낵의 용도로도 사용할 수 있게 개발하고자 하였다. 부각 제조가 상대적으로 간편하며 원료 자체의 색상이 거의 없는 연근을 선정하여 여기에 빨강, 녹색 그리고 노란색을 낼 수 있도록 천연 기능성 색소 소재로 백년초, 녹차 그리고 치자 가루를 사용하였다. 이들 기능성 색소 재료를 삭힌 찹쌀풀 제조 후 첨가하여 다양한 부각을 만들고 이를 말린 후 생 참기름에 튀겨 동맥경화식이에 10%가 되도록 첨가하여 LDLr<SUP>-/-</SUP> 마우스에 10주간 섭취시켜 지질저하기능성을 비교하였다. 실험군은 동맥경화유발식이를 섭취한 wild type mice 대조군(WC), LDLr<SUP>-/-</SUP> mice 대조군(CON), 그리고 동맥경화식이에 다양한 연근부각을 첨가한 연근부각군(LRB), 백년초연근부각군(OFB), 녹차연근부각군(GTB), 그리고 치자연근부각군(GFB)의 총 7군이었다. 부각의 효과를 비교하기 위하여 제한식이를 실시하였다. CON의 혈중 지질 농도는 WC에 비해 유의적으로 높았으며, LRB의 혈중 TG, TC 그리고 LDL-C 농도는 CON에 비해 유의적으로 낮았다(P<0.05). 기능성 색소 재료 첨가에 따른 지질저하 기능성을 살펴보았을 때 OFB와 GTB군의 혈중 TG, TC 그리고 LDL-C 농도가 LRB군에 비해 유의적으로 낮았다(P<0.05). 간의 지방산 합성 효소인 FAS와 콜레스테롤 합성 효소인 HMGCR의 발현 역시 OFB와 GTB군에서 LRB군에 비해 유의적 낮아(P<0.05) 혈중 지질 농도 결과와 일치하였다. 그러나 GFB군의 혈중 지질 농도는 LRB군보다 낮았으나 유의적인 차이를 보이지 않았고, FAS 및 HMGCR 발현 역시 유의적인 차이를 보이지 않았다. FAS 및 HMGCR의 mRNA 발현을 조절하는 전사인자인 SREBP-1과 2의 발현을 살펴보았을 때, OFB군과 GTB군은 LRB군에 비해 각각 유의적으로 낮았으나(P<0.05) GFB군에서는 발현 정도가 낮기는 하였으나 유의적이지 않았다. 이상의 결과로부터 백년초와 녹차 가루를 첨가하여 제조한 연근부각은 LDLr<SUP>-/-</SUP>마우스의 간에서 지방산과 콜레스테롤의 생합성 억제를 통해 혈중 지질의 농도를 낮추는 효과가 있음을 확인하였다. The purpose of this study was to develop functional lotus root bugak with plasma lipid reduction capacity by controlling the color of batter used for bugak preparation. Lotus root, nearly colorless, was selected to observe color effects. Gardeniae fructus (GF), Opuntia ficus-indica var. saboten (OF), and green tea (GT), which are colored yellow, red, and green, respectively, were used as coloring agents. Fermented glutinous rice was prepared naturally during winter season by placing glutinous rice and water (1:2, w/w) together in a crock pot for 7 days. Coloring materials (10%, w/w) were blended with glue made from fermented glutinous rice flour to prepare the batter. Cooked lotus root was then mixed with a 1.1-fold amount of batter (w/w) and dried at room temperature. Lotus root bugak (LRB) is pan-fried with un-roasted sesame oil, which is traditionally used as frying oil in Korea. Low-density lipoprotein receptor knockout (LDLr<SUP>-/-</SUP>) mice (n=36) were fed an atherogenic diet (AD) containing various types of LRB (10 g%) for 10 weeks. Plasma triglyceride, total cholesterol, and LDL-C concentrations decreased significantly in mice fed LRB prepared with OF batter (OFB) and GT batter (GTB) (P<0.05). Protein expression levels of fatty acid synthase (FAS) and 3-hydroxyl-3-methylglutaryl coenzyme A reductase (HMGCR) in the OFB and GTB groups were suppressed compared with the LRB group (P<0.05). In accordance with the results on FAS and HMGCR expression, sterol regulatory element binding protein-Ⅰ and Ⅱ (SREBP-Ⅰ and Ⅱ), which are responsible for the regulation of FAS and HMGCR gene expression, respectively, were down-regulated compared to the LRB group (P<0.05). In conclusion, the plasma lipid reduction activities of OFB and GTB could be mediated through down-regulation of FAS and HMGCR mRNA expression via suppression of regulatory molecules, SREBP-Ⅰ and Ⅱ, in LDLr<SUP>-/- </SUP>mice.

Anti-atherogenic Effects of Functional Sujeonggwa Drinks in Hypercholesterolemic Apo E KO Mice

Aran Baek,Mijeong Kim,Koeun Jung,Seulki Kim,Yeong Ok Song 한국식품영양과학회 2014 한국식품영양과학회 학술대회발표집 Vol.2014 No.10

Ectopic Hard Tissue Formation by Odonto/Osteogenically In Vitro Differentiated Human Deciduous Teeth Pulp Stem Cells.

Kim, Seunghye,Song, Je Seon,Jeon, Mijeong,Shin, Dong Min,Kim, Seong-Oh,Lee, Jae Ho Springer Verlag 2015 Calcified tissue international Vol.97 No.1

<P>There have been many attempts to use the pulp tissue from human deciduous teeth for dentin or bone regeneration. The objective of this study was to determine the effects of odonto/osteogenic in vitro differentiation of deciduous teeth pulp stem cells (DTSCs) on their in vivo hard tissue-forming potential. DTSCs were isolated from extracted deciduous teeth using the outgrowth method. These cells were exposed to odonto/osteogenic stimuli for 4 and 8 days (Day 4 and Day 8 groups, respectively), while cells in the control group were cultured in normal medium. The in vitro differentiated DTSCs and the control DTSCs were transplanted subcutaneously into immunocompromised mice with macroporous biphasic calcium phosphate and sacrificed at 8 weeks post-implantation. The effect of odonto/osteogenic in vitro differentiation was evaluated using alkaline phosphatase (ALP) staining and quantitative reverse transcription polymerase chain reaction (RT-PCR). The in vivo effect was evaluated by qualitative RT-PCR, assessment of ALP activity, histologic analysis, and immunohistochemical staining. The amount of hard tissue was greater in Day 4 group than Day 8 group (p = 0.014). However, Day 8 group generated lamellar bone-like structure, which was immunonegative to anti-human dentin sialoprotein with significantly low expression level of DSPP compared with the control group (p = 0.008). This study demonstrates that odonto/osteogenic in vitro differentiation of DTSCs enhances the formation of bone-like tissue, instead of dentin-like tissue, when transplanted subcutaneously using MBCP as a carrier. The odonto/osteogenic in vitro differentiation of DTSCs may be an effective modification that enhances in vivo bone formation by DTSCs.</P>

A Morphological Processing of Determiner-Noun Agreement by Korean Learners of English

Jeonghwa Cho,Mijeong Song,Sungeun Lee 한국응용언어학회 2018 응용 언어학 Vol.34 No.3

The current study investigated the processing of determiner-noun number agreement by advanced Korean learners of English, with distance and working memory capacity as modulating factors. Twelve English native speakers and eighteen Korean learners of English read English sentences, half of which contained agreement violations, while their EEG data were recorded. The sentences also varied in the distance between determiner and noun (i.e. short distance and long distance). From the data analysis, no LAN effect was observed in both groups in the time window of 300-450 ms. However, only the native group showed a P600 effect (500-600 ms) in response to agreement violations. While short distance conditions overall elicited more positive waveforms than long distance conditions for both groups, the distance did not affect the size of P600. Finally, only the L2 learners with high working memory capacity showed a small P600 effect for short distance conditions at a later time window (700-800 ms). These findings demonstrate that advanced Korean learners do not process number agreement in a native-like way when the grammatical feature is absent in their mother language. Nonetheless, working memory capacity was found to play a moderate role in processing determiner-noun agreement for L2 learners with such aptitude.

Effects of Mineral Trioxide Aggregate on the Proliferation and Differentiation of Human Dental Pulp Stromal Cells from Permanent and Deciduous Teeth

Seunghye Kim,Mijeong Jeon,Dong Min Shin,Jae Ho Lee,Je Seon Song 大韓小兒齒科學會 2013 大韓小兒齒科學會誌 Vol.40 No.3

Mineral trioxide aggregate (MTA) has recently been used as a pulpotomy medicament for primary molars. The aim of this study was to evaluate and compare the proliferation and differentiation potential of dental pulp stromal cells of permanent teeth and deciduous teeth cultured on MTA-coated surface. Human dental pulp stromal cells were obtained from human permanent premolars and deciduous teeth and cultured on MTA-coated culture plates. The cells were subjected to proliferation assay and cell cycle analysis. Their differentiation potential was evaluated by analysing changes in the mRNA expressions of runt-related transcriptional factor 2 (Runx2) and alkaline phosphatase (ALP). Morphological changes of cells in direct contact with MTA were observed using scanning electron microscopy (SEM). The proliferation rates, distribution of cell cycles and mRNA expression patterns of Runx2 and ALP were similar in both types of pulpal cells. SEM observations revealed that both types changed into more dendrite-like cells. On the surface of MTA, human dental pulp stromal cells from deciduous and permanent teeth were able to both proliferate and differentiate into cells that induce mineralization. MTA is suitable as a biocompatible pulpotomy medicament for primary teeth. 최근 유구치의 치수절단술 약제로 MTA의 임상 적용이 문헌들에서 보고된 바 있으나 MTA 표면에서 일어나는 유치 치수세포의 반응에 대한 시험관내 연구는 많이 보고되지 않았다. 이번 연구의 목적은 유치 및 영구치에서 유래한 치수기질세포가경화된 MTA 표면에서 나타내는 증식 및 분화 능력을 비교 평가하는 것이었다. 사람 영구치와 유치 치수 조직에서 분리된 치수기질세포를 경화된 MTA 표면에서 배양 후 세포증식율과 세포주기를 검사하였으며, 정량적 역전사 중합효소 연쇄반응(RT-PCR)을 사용하여 분화양상을 분석하였다. Runt-related transcription factor 2 (Runx2)와 alkaline phosphatase (ALP)가 정량적 RT-PCR의 표지자로 사용되었고, MTA 표면에서 증식된 치수기질세포의 형태학적 변화를 주사전자현미경 하에서 관찰하였다. 영구치와 유치의 치수기질세포군은 세포증식률, 세포주기 분포 및 mRNA 발현 양상에 있어서 차이를 보이지 않았으며, 주사전자현미경 상에서 두 군 모두 수지상 형태를 나타내었다. MTA 상에서 관찰된 유치와 영구치의 치수기질세포의 비슷한 증식력 및 광화를 유도하는 세포로의 분화능은 유치의 치수절단술 제재로 MTA가 생체친화적으로 적합함을 보여준다.