A Network Intrusion Detection Model Based on K-means Algorithm and Information Entropy

Gao Meng,Li Dan,Wang Ni-hong,Liu Li-chen 보안공학연구지원센터 2014 International Journal of Security and Its Applicat Vol.8 No.6

Many factors could influence the clustering performance of K-means algorithm, selection of initial cluster centers was an important one, traditional method had a certain degree of randomness in dealing with this problem, for this purpose, information entropy was introduced into the process of cluster centers selection, and a fusion algorithm combining with information entropy and K-means algorithm was proposed, in which, information entropy value was used to measure the similarity degree among records, the least similar record would be regarded as a cluster center. In addition, a network intrusion detection model was built, it could make cluster centers change dynamically along with the network changes, and the model could real-time update the cluster centers according to actual needs. Experiment results show that the improved algorithm proposed is better than the traditional K-means algorithm in detection ratio and false alarm ratio, and the network intrusion detection model is proved to be feasible.

<나는 누구인가?>를 통해 본 성룡의 정체성 분석

( Gao Meng ),김종갑 ( Kim Jong-gab ) 한양대학교 동아시아문화연구소(구 한양대학교 한국학연구소) 2018 동아시아 문화연구 Vol.74 No.-

“나는 누구인가?”-이것은 정체성에 대한 질문으로, 다문화적이고 다민족적인 현대사회에서 과거의 어느 때보다도 더욱 자주 제기된다. 이 정체성에 대한 문제를, 글로벌 연예인이 된 성룡 (Jackie Chan)을 통해서 접근하는 것이 본 논문의 목표이다. 할리우드에 진출한 그는 홍콩인이면서 중국인이고, 또 그러면서 미국적인 상황에 놓인 자신을 발견한다. 성룡의 <나는 누구인가?>라는 영화의 주인공은 치명적 기억 상실로 인해서 자신이 누구인지를 모르는 인물이다. 잠정적으로 그에게 주어진 이름 Whoami는 한편으로는 자기 자신을 가리키지만 다른 한편으로는 자기 자신이 누구인지를 몰라서 묻는 질문이다. 이와 같이 성룡은 현실에서 홍콩인인가, 중국인인가, 아니면 그 어디에도 속하지 못하는가? 이중 부정인가? 아니면 이중 긍정인가? 사실 모든 홍콩인들은 이러한 정체성의 위기를 겪고 있다. 이 글의 필자는, 성룡은 이 영화와 자신의 삶에서 정체성이란 하나의 주어진 사실이 아니라 만들어가는 과정이라는 점을 보여준다. 즉 일종의 포스트모던적 정체성이다. 뿐만 아니라 성룡은 할리우드에 진출하면서 자신이 빠지는 “셀레브리티 게임”의 규칙도 점차 깨닫게 된다. 즉 셀레브리티는 성룡의 다각적인 정체성의 한 모습이라 엔터테인먼트 산업 아래서 대중매체와 관객들에게 같이 만들어지며 소비되는 이미지이다. 성룡은 이 게임규칙에 따라 자신의 애매한 정체성을 전략적으로 이용하고 더욱 재미있는 문화작품을 제작하고 성공한다. 이 점에서 필자는 그의 정체성은 전략적 정체성이라고 주장한다. “Who am I?”-an essential question that everyone would ask sometime in life; so does Jackie Chan, now a global celebrity who even shouted out this question openly in his film Who Am I? (1998). The paper aims to solve Jackie Chan’s identity dilemma as a global celebrity throughout his transnational crossing from local Hong Kong cinema to global Hollywood. Through Who Am I?(1998), it explores how Chan’s offscreen identity and onscreen personae can be linked together via celebrity mechanism, modern and postmodern identity theories. The paper further argues that Chan’s celebrity is primarily produced by mass media in entertainment industries, such as Hong Kong cinema and Hollywood, and consumed by transnational audiences, thus subject to their authorities as well. Despite early identity crisis, Chan can eventually utilize his ambiguous identity as a survival strategy to stand out from numerous opponents, thereby winning the “celebrity game.” Further studies are needed when it comes to “Who is Jackie Chan?” now, especially with emerging “celebrity logics” on SNSs like Facebook where an online “Jackie Chan” with over 63 million of followers among other top “celebrities,” that is, an online “Jackie Chan”-dominant celebrity.

ANXA2 Regulates the Behavior of SGC-7901 Cells

Sun, Meng-Yao,Xing, Rui-Huan,Gao, Xiao-Jie,Yu, Xiang,He, Hui-Min,Gao, Ning,Shi, Hong-Yan,Hu, Yan-Yan,Wang, Qi-Xuan,Xu, Jin-Hui,Hou, Ying-Chun Asian Pacific Journal of Cancer Prevention 2013 Asian Pacific journal of cancer prevention Vol.14 No.10

ANXA2, a member of the annexin family, is overexpressed and plays important roles in tumor development. However, the significance of ANXA2 expression in gastric carcinoma has not been clarified.To elucidate its roles in growth of gastric cancer, ANXA2 expression in SGC-7901 cells was inhibited with a designated siRNA, then cell proliferation, cell cycling, apoptosis and motility were determined by MTT assay, flow cytometry, Hoechst 33342 staining and wound healing assay, respectively. To further assess the behavior of ANXA2 deleted SGC-7901 cells, changes of microstructures were observed under fluorescence microscopy, laser scanning confocal microscopy and electron microscopy. We found that inhibition of ANXA2 expression caused cell proliferation to decrease significantly with G1 arrest, motility to be reduced with changes in pseudopodia/filopodia structure and F-actin and ${\beta}$-tubulin expression, and apoptosis to be enhanced albeit without significance. At the same time, ANXA2 deletion resulted in fewer pseudopodia/filopodia, non-stained areas were increased, contact inhibition among cells reappeared, and expression of F-actin and ${\beta}$-tubulin was decreased, with induction of polymerized disassembled forms. Taken together, these data suggest that ANXA2 overexpression is important to maintain the malignancy of cancer cells, and this member of the annexin family has potential to be considered as a target for the gene therapy of gastric carcinoma.

A Novel Hybrid Bat Algorithm with Differential Evolution Strategy for Constrained Optimization

Xianbing Meng,X. Z. Gao,Yu Liu 보안공학연구지원센터 2015 International Journal of Hybrid Information Techno Vol.8 No.1

A novel hybrid Bat Algorithm (BA) with the Differential Evolution (DE) strategy using the feasibility-based rules, namely BADE is proposed to deal with the constrained optimization problems. The sound interferences induced by other things are inevitable for the bats which rely on the echolocation to detect and localize the things. Through integration of the DE strategy with BA, the insects’ interferences for the bats can be effectively mimicked by BADE. Moreover, the bats swarm’ mean velocity is simulated as the other bats’ effects on each bat. Having considered the living environments the bats inhabit, the virtual bats can be lifelike. Experiments on some benchmark problems and engineering designs demonstrate that BADE performs more efficient, accurate, and robust than the original BA, DE, and some other optimization methods.

Field Load Testing Study of Vertical Bearing Behavior of a Large Diameter Belled Cast-in-Place Pile

Guangyun Gao,Meng Gao,Qingsheng Chen,Jun Yang 대한토목학회 2019 KSCE JOURNAL OF CIVIL ENGINEERING Vol.23 No.5

To investigate the vertical bearing behavior of manually excavated large diameter belled concrete piles (LDBCPs), field loading tests were performed on a total of 16 LDBCPs, ranging from 0.8 to 3.5 m in base diameter from 6.1 to 18.0 m in embedment length. The end bearing stratum is sand and gravel. The influence of pile dimensions (i.e., size of enlarged base D, embedment length L, and length-to-diameter ratio L/D) on the vertical bearing behavior of a belled pile is presented and discussed. Comparison is also made of the vertical bearing behavior of a belled pile and of a conventional straight pile under otherwise similar conditions. The results indicate that: 1) The vertical bearing capacity of a belled pile is significantly greater than that of a conventional straight pile provided the debris at the bottom of a belled pile is properly removed; 2) over 65% of the vertical bearing capacity for a belled pile is attributed to the tip resistance (Qe); 3) compared to the contribution of pile length L, increasing enlarged base D is a more effective way to increase the vertical ultimate bearing capacity of a belled pile (Qu); 4) the optimum length-to-enlarged base ratio (L/D) for belled piles to achieve maximum vertical bearing capacity is around 3.2.

Genomic diversity of the Avian leukosis virus subgroup J gp85 gene in different organs of an infected chicken

Fanfeng Meng,Xue Li,Jian Fang,Yalong Gao,Lilong Zhu,Guiju Xing,Fu Tian,Yali Gao,Xuan Dong,Shuang Chang,Peng Zhao,Zhizhong Cui,Zhihao Liu 대한수의학회 2016 Journal of Veterinary Science Vol.17 No.4

The genomic diversity of Avian leukosis virus subgroup J (ALV-J) was investigated in an experimentally infected chicken. ALV-J variantsin tissues from four different organs of the same bird were re-isolated in DF-1 cells, and their gp85 gene was amplified and cloned. Ten clonesfrom each organ were sequenced and compared with the original inoculum strain, NX0101. The minimum homology of each organ rangedfrom 96.7 to 97.6%, and the lowest homology between organs was only 94.9%, which was much lower than the 99.1% homology of inoculumNX0101, indicating high diversity of ALV-J, even within the same bird. The gp85 mutations from the left kidney, which contained tumors,and the right kidney, which was tumor-free, had higher non-synonymous to synonymous mutation ratios than those in the tumor-bearing liverand lungs. Additionally, the mutational sites of gp85 gene in the kidney were similar, and they differed from those in the liver and lung, implyingthat organ- or tissue-specific selective pressure had a greater influence on the evolution of ALV-J diversity. These results suggest that moreALV-J clones from different organs and tissues should be sequenced and compared to better understand viral evolution and molecularepidemiology in the field.

Soluble Epoxide Hydrolase Inhibitory and Anti-inflammatory Components from the Leaves of <i>Eucommia ulmoides</i> Oliver (Duzhong)

Bai, Meng-Meng,Shi, Wei,Tian, Jun-Mian,Lei, Ming,Kim, Jang Hoon,Sun, Ya Nan,Kim, Young Ho,Gao, Jin-Ming American Chemical Society 2015 Journal of agricultural and food chemistry Vol.63 No.8

<P><I>Eucommia ulmoides</I> leaves have been used as a functional food and drink in China. The purpose of this study was to identify the bioactive constituents with soluble epoxide hydrolase (sEH) inhibitory activity and anti-inflammatory properties. Twenty-seven known compounds (<B>1</B>–<B>27</B>) were isolated from the leaves of <I>E. ulmoides</I> Oliver, and their structures were identified by NMR and ESIMS analysis; three of these, 2,5-dimethoxy-3-glucopyranosyl cinnamic alcohol (<B>11</B>), foliasalacioside E<SUB>2</SUB> (<B>26</B>), and icariside F<SUB>2</SUB> (<B>27</B>), were obtained from this plant for the first time. Compounds <B>1</B>–<B>7</B> exhibited soluble epoxide hydrolase (sEH) inhibitory activity at 100 μM; among them, quercetin (<B>1</B>) and kaempferol (<B>5</B>) displayed potential activities with IC<SUB>50</SUB> values of 22.5 ± 0.9 and 31.3 ± 2.6 μM, respectively, with noncompetitive inhibition mode. Nuclear factor kappa B (NF-κB) inhibitory activity of the isolated compounds was evaluated by the NF-κB liciferase assay in HepG2 cells. Compounds <B>1</B>, <B>9</B>, <B>20</B>, and <B>27</B> displayed potent NF-κB inhibitory effects, with IC<SUB>50</SUB> values of 15.14 ± 2.29, 15.23 ± 2.34, 16.88 ± 2.17, and 16.25 ± 2.19 μM, respectively, whereas other compounds showed weak inhibition of NF-κB transcriptional activity ranging from 17.54 to 92.6 μM. A structure–activity relationship of flavonoids <B>1</B>–<B>9</B> was also discussed. The results obtained in this work might contribute to the understanding of pharmacological activities of <I>E. ulmoides</I> leaves and further investigation on its potential application values for food and drug.</P><P><B>Graphic Abstract</B> <IMG SRC='http://pubs.acs.org/appl/literatum/publisher/achs/journals/content/jafcau/2015/jafcau.2015.63.issue-8/acs.jafc.5b00055/production/images/medium/jf-2015-00055j_0004.gif'></P><P><A href='http://pubs.acs.org/doi/suppl/10.1021/jf5b00055'>ACS Electronic Supporting Info</A></P>

Position-based Data Dissemination to Interested Region in VANETs

Shuoping Wang,Meng Kuai,Honghao Gao 보안공학연구지원센터 2014 International Journal of Grid and Distributed Comp Vol.7 No.5

Vehicular Ad-hoc Networks (VANETs) are expected to provide assistance to various applications, such as accident broadcast or emergency notification. Some kinds of applications need data to be delivered in a certain region by geocast, which means disseminating information in a specific area, instead of using a certain IP address. In this paper, we propose a data dissemination protocol for VANETs, which delivers data to all the vehicles in an interested region. We assume each vehicle is equipped with GPS and DSRC devices. Our simulation results show that this data dissemination protocol can contribute to high delivery ratio. Also, it performs well in adaptability during heavy traffic.

microRNA-328 in exosomes derived from M2 macrophages exerts a promotive effect on the progression of pulmonary fibrosis via FAM13A in a rat model

Meng-Ying Yao,Wei-Hong Zhang,Wen-Tao Ma,Qiu-Hong Liu,Li-Hua Xing,Gao-Feng Zhao 생화학분자생물학회 2019 Experimental and molecular medicine Vol.51 No.-

Currently, exosome-enclosed microRNAs (miRs) in exhaled breath have potential for biomarker discovery in patients with pulmonary diseases. This study was performed to investigate the roles of M2 macrophage-derived exosomes expressing miR-328 in pulmonary fibrosis (PF). Microarray-based analysis was used to screen differentially expressed genes (DEGs) and regulatory miRs in PF. The miR-target relationship between FAM13A and miR-328 was confirmed. The expression of FAM13A and miR-328 was measured in PF rats, and gain- and loss-of-function assays were conducted to determine the regulatory effects of FAM13A and miR-328 on PF. In addition, exosomes derived from M2 macrophages were isolated and then cocultured with pulmonary interstitial fibroblasts to identify the role of these exosomes in PF. Furthermore, the effects of M2 macrophage-derived exosomes overexpressing miR-328 on pulmonary fibroblast proliferation and the progression of PF were assessed in vivo. miR-328 might perform a vital function in PF by regulating FAM13A. FAM13A expression was downregulated while miR-328 expression was upregulated in rats with PF, and a miR-target relationship between miR-328 and FAM13A was observed. Additionally, miR-328 overexpression and FAM13A silencing each were suggested to promote pulmonary interstitial fibroblast proliferation and the expression of Collagen 1A, Collagen 3A and α-SMA. Then, in vitro experiments demonstrated that M2 macrophage-derived exosomes overexpressing miR-328 contributed to enhanced pulmonary interstitial fibroblast proliferation and promoted PF. Furthermore, in vivo experiments confirmed the promotive effects of M2 macrophagederived exosomes overexpressing miR-328 on the progression of PF. Collectively, the results showed that

Use of Fluorescence Imaging in Combination with Patent Blue Dye versus Patent Blue Dye Alone in Sentinel Lymph Node Biopsy in Breast Cancer

Meng Tong,Wenbin Guo,Wei Gao 한국유방암학회 2014 Journal of breast cancer Vol.17 No.3

Purpose: Near-infrared fluorescence imaging with indocyaninegreen (ICG) has the potential to improve sentinel lymph node(SLN) mapping in breast cancer. In this clinical trial, we comparedthe potential value of ICG combined with blue dye withthat of blue dye alone for detecting SLNs. Methods: Patients undergoingSLN biopsy (SLNB) between November 2010 and November2013 were included. Up to December 2011, SLNs weredetected by using patent blue (PB) alone, and since January2012, by using PB in combination with ICG. The patients weredivided into the following two groups: group A (ICG-PB; n=96)and group B (PB; n=73), and SLN detection parameters werecompared between the groups. All patients underwent level Iand II axillary dissections after SLNB. Results: In group A, theSLN detection rate was 96.9% (93/96), the accuracy of detectionwas 98.9% (92/93), and the false-negative rate (FNR) was3.4% (1/29). In group B, the SLN detection rate was 84.9%(62/73), the accuracy of detection was 96.8% (60/62), and theFNR was 11.1% (2/18). The ICG-PB group showed significantlysuperior results compared to the PB group for SLN detection(p=0.005) and a greatly improved FNR. Conclusion: The combinedfluorescence and blue dye-based tracer technique wassuperior to the use of blue dye alone for identifying SLNs, andfor predicting axillary lymph node status in patients with breastcancer; in addition, the combined technique had reduced falsenegativeresults.