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      • SCIESCOPUSKCI등재

        A Novel AE Based Algorithm for PD Localization in Power Transformers

        Mehdizadeh, Sina,Yazdchi, Mohammadreza,Niroomand, Mehdi The Korean Institute of Electrical Engineers 2013 Journal of Electrical Engineering & Technology Vol.8 No.6

        In this paper, a novel algorithm for PD localization in power transformers based on wavelet de-noising technique and energy criterion is proposed. Partial discharge is one of the main failures in power transformers. The localization of which could be very useful for maintenance systems. Acoustic signals due to a PD event are transient, irregular and non-repetitive. So wavelet transform is an efficient tool for this signal processing problem that gives a time-frequency demonstration. First, different wavelet based de-noising methods are analyzed. Then, a reasonable structure for threshold value determining and applying manner on signals is presented. Evaluated errors are good evidences for choices. Next, applying the elimination low energy frequency bands is discussed and developed as a de-noising method. Time differences between signals are used for PD localization. Different ways in time arrival detection are introduced and a novel approach in energy criterion method is presented. At the end, the quality of algorithm is verified through the different assays in lab.

      • KCI등재

        A Novel AE Based Algorithm for PD Localization in Power Transformers

        Sina Mehdizadeh,Mohammadreza Yazdchi,Mehdi Niroomand 대한전기학회 2013 Journal of Electrical Engineering & Technology Vol.8 No.6

        In this paper, a novel algorithm for PD localization in power transformers based on wavelet de-noising technique and energy criterion is proposed. Partial discharge is one of the main failures in power transformers. The localization of which could be very useful for maintenance systems. Acoustic signals due to a PD event are transient, irregular and non-repetitive. So wavelet transform is an efficient tool for this signal processing problem that gives a time-frequency demonstration. First, different wavelet based de-noising methods are analyzed. Then, a reasonable structure for threshold value determining and applying manner on signals is presented. Evaluated errors are good evidences for choices. Next, applying the elimination low energy frequency bands is discussed and developed as a de-noising method. Time differences between signals are used for PD localization. Different ways in time arrival detection are introduced and a novel approach in energy criterion method is presented. At the end, the quality of algorithm is verified through the different assays in lab.

      • KCI등재후보

        Frequency, shape, and estimated volume of intracranial physiologic calcification in different age groups investigated by brain computed tomography scan: a retrospective study

        Mehrdad Ghorbanlou,Fatemeh Moradi,Mehdi Mehdizadeh 대한해부학회 2022 Anatomy & Cell Biology Vol.55 No.1

        Intracranial calcification is referred to calcification of parenchyma and vascular structures in brain which can be physiologic or pathologic. This study was conducted with the purpose of investigating the frequency, location, pattern, dimensions and estimated volume of intracranial physiologic calcification (IPC) by computer tomography in different age groups. In this cross-sectional retrospective study, brain computed tomography scans of 216 patients were analyzed in 9 age groups each containing 24 patients from 2 to 89 years old. Data were analyzed by SPSS software using one way analysis of variance (ANOVA, post hoc Tukey), chi square, and linear regression tests (P≤0.05 was considered significant). Rate of calcification in different areas were as follows: pineal gland (75.0%), habenula (36.4%), pineohabenula (15.0%), right lateral ventricle choroid plexus (RCP) (67.7%), left lateral ventricle choroid plexus (LCP) (62.7%), falx cerebri (26.8%), petroclinoid ligament (13.2%), tentorium cerebelli (6.8%), third ventricle choroid plexus (0.9%), fourth ventricle choroid plexus (2.7%), basal ganglia (0.9%). A significant correlation exists between the presence of calcification in pineal, habenula, RCP, and LCP (P≤0.001). Nodular shape of calcification was dominant (47.9%). Estimated volume of pineal calcification showed increased levels in group 8 (70-79 years old) compared to group 2 (10-19 years old) (P≤0.05). Since the accurate description of radiologic appearance of IPCs (location, shape, and size) accompanied with age and clinical manifestation is of great importance in diagnosis and distinguishing from pathologic calcification—for example in patients with melatonin dysregulation or schizophrenic patients—this study was required.

      • KCI등재

        Health concerns regarding the effect of the COVID-19 pandemic on male fertility

        Hamidreza Mosleh,Fatemeh Moradi,Mehdi Mehdizadeh,Marziyeh Ajdary,Alaa Moeinzadeh,Ronak Shabani 대한생식의학회 2021 Clinical and Experimental Reproductive Medicine Vol.48 No.3

        Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is a novel coronavirus found in China in 2019. The disease caused by SARS-CoV-2, coronavirus disease 2019 (COVID-19), has been found to be closely related to the cells that secrete angiotensin-converting enzyme 2 (ACE2). ACE2 is involved in the renin-angiotensin system and is widely secreted in several tissues, including the testis, which has raised concerns because organs with high expression of the ACE2 receptor are susceptible to infection. Analyses have shown that in testicular cells, such as spermatogonia, seminiferous duct cells, Sertoli cells, and Leydig cells, there is a high expression level of ACE2. Therefore, SARS-CoV-2 may damage male reproductive tissues and cause infertility. Since male infertility is an important problem, scientists are evaluating whether COVID-19 may influence male infertility through the ACE2 receptor.

      • SCOPUSKCI등재

        Evaluation of polyglycolic acid as an animal-free biomaterial for three-dimensional culture of human endometrial cells

        Sadegh Amiri,Zohreh Bagher,Azadeh Akbari Sene,Reza Aflatoonian,Mehdi Mehdizadeh,Peiman Broki Milan,Leila Ghazizadeh,Mahnaz Ashrafi,FatemehSadat Amjadi The Korean Society for Reproductive Medicine 2022 Clinical and Experimental Reproductive Medicine Vol.49 No.4

        Objective: Animal-free scaffolds have emerged as a potential foundation for consistent, chemically defined, and low-cost materials. Because of its good potential for high biocompatibility with reproductive tissues and well-characterized scaffold design, we investigated whether polyglycolic acid (PGA) could be used as an animal-free scaffold instead of natural fibrin-agarose, which has been used successfully for three-dimensional human endometrial cell culture. Methods: Isolated primary endometrial cells was cultured on fibrin-agarose and PGA polymers and evaluated various design parameters, such as scaffold porosity and mean fiber diameter. Cytotoxicity, scanning electron microscopy (SEM), and immunostaining experiments were conducted to examine cell activity on fabricated scaffolds. Results: The MTT (3-[4,5-dimethylthiazol-2-yl]-2,5 diphenyl tetrazolium bromide) assay and SEM results showed that endometrial cells grew and proliferated on both scaffolds. Immunostaining showed cytokeratin and vimentin expression in seeded cells after 7 days of culture. On both scaffolds, an epithelial arrangement of cultured cells was found on the top layer and stromal arrangement matrix on the bottom layer of the scaffolds. Therefore, fibrin-agarose and PGA scaffolds successfully mimicked the human endometrium in a way suitable for in vitro analysis. Conclusion: Both fibrin-agarose and PGA scaffolds could be used to simulate endometrial structures. However, because of environmental and ethical concerns and the low cost of synthetic polymers, we recommend using PGA as a synthetic polymer for scaffolding in research instead of natural biomaterials.

      • SCOPUSKCI등재

        Transition nuclear protein 1 as a novel biomarker in patients with fertilization failure

        Jamileh Sadat Mirsanei,Hadis Gholipour,Zahra Zandieh,Masoumeh Golestan Jahromi,Mojgan Javedani Masroor,Mehdi Mehdizadeh,Fatemehsadat Amjadi The Korean Society for Reproductive Medicine 2023 Clinical and Experimental Reproductive Medicine Vol.50 No.3

        Objective: Although intracytoplasmic sperm injection (ICSI) is a way to deal with in vitro fertilization failure, 3% of couples still experience repeated fertilization failure after attempted ICSI, despite having sperm within normal parameters. These patients are a challenging group whose sperm cannot fertilize the egg during ICSI. Unfortunately, no test can predict the risk of fertilization failure. Phospholipase C zeta (PLCζ) and transition nuclear proteins (TNPs) are essential factors for chromatin packaging during sperm maturation. This study aimed to assess PLCζ1 and TNP1 expression in the sperm of patients with fertilization failure and the correlations among the DNA fragmentation index, PLCζ1 and TNP1 gene and protein expression, and the risk of fertilization failure. Methods: In this study, 12 infertile couples with low fertilization rates (<25%) and complete failure of fertilization in their prior ICSI cycles despite normal sperm parameters were chosen as the case group. Fifteen individuals who underwent ICSI for the first time served as the control group. After sperm analysis and DNA fragmentation assays, quantitative reverse-transcription polymerase chain reaction (qRT-PCR) and Western blot analyses were performed to compare the gene and protein expression of PLCζ and TNP1 in both groups. Results: DNA fragmentation was significantly higher in the fertilization failure group. The qRT-PCR and Western blot results demonstrated significantly lower PLCζ and TNP1 gene and protein expression in these patients than in controls. Conclusion: The present study showed that fertilization failure in normozoospermic men was probably due to deficient DNA packaging and expression of TNP1.

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