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Comorbidity Between Anorexia Nervosa and Depressive Disorder: A Narrative Review
Maria Pilar Calvo-Rivera,Maria Isabel Navarrete-Páez,Isabel Bodoano,Luis Gutiérrez-Rojas 대한신경정신의학회 2022 PSYCHIATRY INVESTIGATION Vol.19 No.3
Objective Anorexia nervosa (AN) is a disorder with a significantly high prevalence. Affective disorders, including depressive disorder (DD), often coexist with this eating disorder (ED). In this review we will focus on its prevalence, associated vulnerability factors, clinical manifestations, possible etiological factors and its prognosis.Methods A bibliographic search was carried out in the PubMed database selecting those articles that approached the subject of comorbidity between AN and DD. The search was limited to articles published from January 1990 to December 2021.Results Of the 1891 abstracts reviewed, 33 studies met inclusion criteria. The prevalence of this comorbidity was extremely variable between studies, which exposed their heterogeneity. As to symptomatology this comorbidity presents itself with more severity, greater expression of psychological traits and greater cognitive impairment. Certain personality traits are postulated as vulnerability factors. Genetic factors such as neurochemicals seem to be involved in its pathogenesis.Conclusion The comorbidity between DD and ED have important influence in its symptomatic expression, severity and prognosis. Some of the analyzed studies provide consistent data, but there are others that are contradictory. It would be necessary to increase the number of studies and use a unified methodology.
Prognostic role of genetic biomarkers in clinical progression of prostate cancer
Maria Jesus Alvarez-Cubero,Luis Javier Martinez-Gonzalez,Maria Saiz,Pedro Carmona-Saez,Juan Carlos Alvarez,Manrique Pascual-Geler,Jose Antonio Lorente,Jose Manuel Cozar 생화학분자생물학회 2015 Experimental and molecular medicine Vol.47 No.-
The aim of this study was to analyze the use of 12 single-nucleotide polymorphisms in genes ELAC2, RNASEL and MSR1 as biomarkers for prostate cancer (PCa) detection and progression, as well as perform a genetic classification of high-risk patients. A cohort of 451 men (235 patients and 216 controls) was studied. We calculated means of regression analysis using clinical values (stage, prostate-specific antigen, Gleason score and progression) in patients and controls at the basal stage and after a follow-up of 72 months. Significantly different allele frequencies between patients and controls were observed for rs1904577 and rs918 (MSR1 gene) and for rs17552022 and rs5030739 (ELAC2). We found evidence of increased risk for PCa in rs486907 and rs2127565 in variants AA and CC, respectively. In addition, rs627928 (TT–GT), rs486907 (AG) and rs3747531 (CG–CC) were associated with low tumor aggressiveness. Some had a weak linkage, such as rs1904577 and rs2127565, rs4792311 and rs17552022, and rs1904577 and rs918. Our study provides the proof-of-principle that some of the genetic variants (such as rs486907, rs627928 and rs2127565) in genes RNASEL, MSR1 and ELAC2 can be used as predictors of aggressiveness and progression of PCa. In the future, clinical use of these biomarkers, in combination with current ones, could potentially reduce the rate of unnecessary biopsies and specific treatments.
Real Exchange Rates in Latin America : The PPP Hypothesis and Fractional Integration
GUGLIELMO MARIA CAPORALE;LUIS A. GIL-ALANA 경제연구소 2010 Journal of Economic Development Vol.35 No.2
This paper tests for PPP in a group of seventeen Latin American (LA) countries by applying fractional integration techniques to real exchange rate series. Compared to earlier studies on these economies, this approach has the advantage of allowing for non-integer values for the degree of integration, and thus for the possibility of PPP not holding continuously but as a long-run equilibrium condition. Further, breaks in the series are endogenously determined using a procedure based on the least-squares principle. This is particularly crucial in the Latin American countries, which have been affected by several exchange rate crises and policy regime changes. The results, based on different assumptions about the underlying disturbances, are in the majority of cases inconsistent with PPP, even more so when breaks are incorporated: Argentina is the only country for which clear evidence of mean reversion is found in the model including a break, albeit only in the second subsample.
Fungal diversity in soils across a gradient of preserved Brazilian Cerrado
Ademir Sergio Ferreira de Araujo,Walderly Melgaço Bezerra,Vilma Maria dos Santos,Luis Alfredo Pinheiro Leal Nunes,Maria do Carmo Catanho Pereira de Lyra,Marcia do Vale Barreto Figueired,Vania Maria Ma 한국미생물학회 2017 The journal of microbiology Vol.55 No.4
The preserved Cerrado from Northeastern Brazil presentsdifferent physicochemical properties and plant diversity,which can influence the fungal communities. Therefore, weevaluated the fungal diversity in preserved sites, at Sete CidadesNational Park, across a gradient of vegetation that includedCampo graminoide, Cerrado stricto sensu, Cerradao,and Floresta decidual. Of all of the operational taxonomicunits (OTUs) obtained, the Floresta decidual presented thehighest richness. Ascomycota were the most abundant phylum(45%), followed by Basidiomycota (32%). Basal fungiand other phyla accounted for 23% of the total dataset. Agaricomycetes, Eurotiomycetes, Lecanoromycetes, Basidiobolus,Dothideomycetes, and Taphrinomycetes were themost abundant classes of fungi found across the gradient ofCerrado vegetation. In conclusion, our study suggests thatthe Brazilian Cerrado from Sete Cidades National Park presentsa high fungal diversity and includes sources of newfungal species for biotechnological purposes.
Luis Souza Lima de Souza Reis,Neuza Maria Frazatti-Gallina,Rosana de Lima Paoli,Rogerio Giuffrida,Avelino Albas,Eunice Oba,Paulo Eduardo Pardo 대한수의학회 2008 Journal of Veterinary Science Vol.9 No.4
This study evaluated the effect of Matricaria chamomilla and vaccination frequency on cattle immunization against rabies. Four groups (n = 15 /group) were treated with or without Matricaria chamomilla CH12 and vaccinated with one or two doses of rabies vaccine (30 day interval). No effect of chamomile was found on cattle immunization against rabies; however, antibody titers were protective in cattle vaccinated twice, while 93.3% of cattle vaccinated only once had titers under 0.5 UI/ml after 60 days. In conclusion, the use of chamomile did not alter the humoral immune response in cattle, and two vaccine doses are suggested for achieving protective antibody titers.
Chronic Management of Hypertension after Stroke: The Role of Ambulatory Blood Pressure Monitoring
Luis Castilla-Guerra,Maria del Carmen Fernandez-Moreno 대한뇌졸중학회 2016 Journal of stroke Vol.18 No.1
Hypertension is the most important potentially reversible risk factor for stroke in all age groups; high blood pressure (BP) is also associated with increased risk of recurrent stroke in patients who have already had an ischemic or hemorrhagic event. Twenty-four hour ambulatory BP monitoring (ABPM) has become an important tool for improving the diagnosis and management of hypertension, and is increasingly used to assess patients with hypertension. Nevertheless, although ABPM devices are increasingly used for assessment of hypertension, their value in the chronic management of hypertension in patients with stroke has not been systematically studied. In fact, among large-scale randomized trials for secondary stroke prevention, only the Morbidity and Mortality After Stroke, Eprosartan Compared With Nitrendipine for Secondary Prevention trial included 24-hour ABPM. ABPM has demonstrated chronic disruption of the circadian rhythm of BP after acute phase of stroke and has shown higher sensitivity compared to office BP in evaluating the effectiveness of antihypertensive treatment among stroke survivors. High 24-hour BP is an independent predictor for cerebrovascular events, brain microbleeds, and subsequent development of dementia. Nevertheless, although stroke care guidelines endorse the importance of hypertension management, the specific role of ABPM among stroke survivors after the acute phase of disease has not been established. Further studies are needed to clarify whether routine application of ABPM among these patients should be recommended.
Personal Exposure to PM2.5 in the Massive Transport System of Bogotá and Medellín, Colombia
Maria Paula Castillo-Camacho,Isabel Cristina Tunarrosa-Grisales,Lina María Chacón-Rivera,Marco Andrés Guevara Luna,Luis Carlos Belalcázar Cerón 한국대기환경학회 2020 Asian Journal of Atmospheric Environment (AJAE) Vol.14 No.3
Recent studies have shown that public transport users can be exposed to high levels of pollution emitted from their own vehicles and nearby sources. The purpose of this research is to determine the personal exposure of passengers to PM2.5 inside the vehicles of the massive public transport of two of the main and more populated cities of Colombia, Bogotá and Medellín. TM (TransMilenio powered by diesel) and SITVA (electric and gas natural vehicles) were the systems studied. Were evaluated the integration of new vehicles with technologies Euro V and Euro VI in the TM system, the impact of the weekend effect on personal exposure into public transport(TM and SITVA), and the possible differences between personal exposure regarding the ways of the systems(mixed lane or exclusive lane for TM and SITVA). To measure PM2.5 levels, a DustTrak monitor previously calibrated was used. This measurement campaigns lasted for more than 80 hours and a mean of 17000 data of PM2.5 concentrations were obtained for each route. The personal dose was calculated based on the recorded data. The mean PM2.5 concentrations and personal dose found in the research for TM are 167 µg/m³ and 2.3 µg/min, respectively, while, for SITVA they are 41 µg/m³ and 0.53 µg/min, respectively. Therefore, SITVA users have a 5 times lower personal exposure to PM2.5 than TM users. It was also found that due to the poor proportion of new TM vehicles during the monitoring period, the personal exposure in the old vehicles and in the new ones is similar. In the case of SITVA, it was evidenced that the mixed lane contributes to a high personal exposure to PM2.5 than the exclusive one.