http://chineseinput.net/에서 pinyin(병음)방식으로 중국어를 변환할 수 있습니다.
변환된 중국어를 복사하여 사용하시면 됩니다.
Visible Emission Properties of V₂O<SUB>5</SUB> Nanorods Prepared by Different Growth Methods
Manil Kang,Sok Won Kim,Ji-Wook Ryu 한국진공학회(ASCT) 2014 Applied Science and Convergence Technology Vol.23 No.5
α-V₂O? nanorods were grown by means of electron beam irradiation and thermal oxidation methods and the visible emission properties of the nanorods grown by both methods were investigated. The growth and crystallinity of the nanorods were greatly enhanced by the insertion of a buffer layer. The emission spectra of the nanorods grown by thermal oxidation and electron beam irradiation showed a peak centered at 710∼720 nm, which is believed to be due to oxygen vacancies introduced during the growth process. Also, the emission peak centered at 530 nm observed in the V₂O? nanorods grown by electron beam irradiation was considered to be due to the band edge transition as a result of the enhanced crystallinity.
Kukkar, Manil,Tuteja, Satish K.,Sharma, Amit L.,Kumar, Vinod,Paul, Ashok K.,Kim, Ki-Hyun,Sabherwal, Priyanka,Deep, Akash American Chemical Society 2016 ACS APPLIED MATERIALS & INTERFACES Vol.8 No.26
<P>We report an efficient method for the synthesis of few-layered MoS2 nanosheets and demonstrate their application in the label-free detection of the prostate-specific antigen (PSA) cancer marker. As a novel strategy, the electro-dissolution of molybdenum metal sheets in the presence of Na+ and S2- ions led to the formation of Na+ intercalated MoS2. Further exfoliation by ultrasonication yielded the desired formation of few-layered MoS2 nanosheets. After comprehensive characterization, the synthesized MoS2 nanosheets were channeled in a field-effect transistor (FET) microdevice. Chemically reduced anti-PSA antibodies were immobilized on the MoS2 channel above the FET microdevice to construct a specific PSA immunosensor. The antibodies were deliberately reduced to expose the hinge-region disulfide bonds. This approach offered a robust and site-directed immunosensing device through biointerfacing of the sulfhydryl groups (SH) in the reduced antibody with the surface S atoms of MoS2. This device was validated as an effective immunosensor with a low detection limit (10(-5)ng/mL) over a wide linear detection range (10(-5) to 75 ng/mL).</P>
Kukkar, Manil,Tuteja, Satish K.,Kumar, Parveen,Kim, Ki-Hyun,Bhadwal, Akhshay Singh,Deep, Akash Elsevier 2018 Analytical Biochemistry Vol.555 No.-
<P><B>Abstract</B></P> <P>The application of molybdenum disulfide (MoS<SUB>2</SUB>) nanosheets has assumed great significance in the design of next-generation biosensors. The immobilization of biomolecules on MoS<SUB>2</SUB> nanosheets has generally been achieved via hydrophobic interactions or through other complicated surface modifications. In this work, we report a novel strategy for electrochemically assisted amine derivatization of MoS<SUB>2</SUB> nanosheets. This newly proposed approach helped to immobilize the MoS<SUB>2</SUB> nanosheets with antibodies via facile EDC/NHS {N-(3-dimethylaminopropyl)-N-(ethylcarbodiimide/N-hydroxysuccinimide)} cross-linking chemistry. The MoS<SUB>2</SUB> nanosheets were first exfoliated and then electrochemically modified with 2-aminobenzylamine. Through a subsequent bioconjugation of the above amine-derivatized MoS<SUB>2</SUB> nanosheets with anti-prostate-specific antigen (PSA) antibodies, an immunosensing device was realized for the detection of the ‘prostate specific antigen’. The application of the proposed immunosensor was characterized with a low detection limit (10<SUP>−3</SUP> ng/mL) over a very wide quantitation range (10<SUP>−3</SUP> to 200 ng/mL).</P> <P><B>Highlights</B></P> <P> <UL> <LI> The bioconjugation of MoS<SUB>2</SUB> nanosheets has been processed with a novel strategy. </LI> <LI> MoS<SUB>2</SUB> nanosheets were exfoliated and electrochemically modified with 2-aminobenzylamine. </LI> <LI> MoS<SUB>2</SUB> nanosheets have been interfaced with antibodies via facile EDC/NHS cross-linking chemistry. </LI> <LI> MoS<SUB>2</SUB> nanosheets immunosensor for PSA has offered a low detection limit and a very wide range of analysis. </LI> </UL> </P>
A comprehensive review on nano-molybdenum disulfide/DNA interfaces as emerging biosensing platforms
Kukkar, Manil,Mohanta, Girish C.,Tuteja, Satish K.,Kumar, Parveen,Bhadwal, Akhshay Singh,Samaddar, Pallabi,Kim, Ki-Hyun,Deep, Akash Elsevier 2018 Biosensors & Bioelectronics Vol.107 No.-
<P><B>Abstract</B></P> <P>The development of nucleic acid-based portable platforms for the real-time analysis of diseases has attracted considerable scientific and commercial interest. Recently, 2D layered molybdenum sulfide (2D MoS<SUB>2</SUB> from here on) nanosheets have shown great potential for the development of next-generation platforms for efficient signal transduction. Through combination with DNA as a biorecognition medium, MoS<SUB>2</SUB> nanostructures have opened new opportunities to design and construct highly sensitive, specific, and commercially viable sensing devices. The use of specific short ssDNA sequences like aptamers has been proven to bind well with the unique transduction properties of 2D MoS<SUB>2</SUB> nanosheets to realize aptasensing devices. Such sensors can be operated on the principles of fluorescence, electro-cheumuluminescence, and electrochemistry with many advantageous features (e.g., robust biointerfacing through various conjugation chemistries, facile sensor assembly, high stability with regard to temperature/pH, and high affinity to target). This review encompasses the state of the art information on various design tactics and working principles of MoS<SUB>2</SUB>/DNA sensor technology which is emerging as one of the most sought-after and valuable fields with the advent of nucleic acid inspired devices. To help achieve a new milestone in biosensing applications, great potential of this emerging technique is described further with regard to sensitivity, specificity, operational convenience, and versatility.</P> <P><B>Highlights</B></P> <P> <UL> <LI> In this review, an outlook of 2-D nanomaterial inspired biosensors is described. </LI> <LI> This article focused on MoS<SUB>2</SUB>-DNA/aptamer biosensors and their practical applications. </LI> <LI> 2-D MoS<SUB>2</SUB>-DNA interfaces are recognized as the next-generation biosensors. </LI> </UL> </P>