A New Septum in the Female Breast

Mostafa Abdel Rahman Awad,Mahmoud Magdi Sherif,Eaman Yahya Sadek,Hesham Aly Helal,Wafaa Raafat Abdel Hamid 대한성형외과학회 2017 Archives of Plastic Surgery Vol.44 No.2

Background Understanding the female breast fascial system is of paramount importance in breast surgery. Little was written about breast ligaments. Most articles refer to Cooper’s work without further anatomical studies. Lately, a horizontal septum has been described conveying nerves and vessels to the nipple areola complex. Methods During the surgical dissection of the lower part of the breast, in supero-medial technique for breast reduction operations, a fascial septum between the lower two quadrants was detected. This fibrous septum was studied through anatomic dissection of breast tissues during routine breast reshaping procedures that was done on 30 female patients. Magnetic resonance imaging (MRI) was performed preoperatively in all cases and correlated with the intraoperative findings. In the other five cases, outside the clinical study, the imaging was done during routine investigation for breast swellings. Results A vertical septum was identified in the lower part of the breast, lying at the breast meridian between the two lower quadrants. It is a tough bi-laminated structure that extends from the middle of the infra-mammary crease caudally to nipple-areola complex cranially and from the pectoral fascia posteriorly to the overlying skin anteriorly. This was proved by MRI findings. Conclusions This study describes a new inferior vertical septum which separates the lower half of the breast into two definite anatomical compartments: medial and lateral.

A New Septum in the Female Breast

Awad, Mostafa Abdel Rahman,Sherif, Mahmoud Magdi,Sadek, Eaman Yahya,Helal, Hesham Aly,Hamid, Wafaa Raafat Abdel Korean Society of Plastic and Reconstructive Surge 2017 Archives of Plastic Surgery Vol.44 No.2

Background Understanding the female breast fascial system is of paramount importance in breast surgery. Little was written about breast ligaments. Most articles refer to Cooper's work without further anatomical studies. Lately, a horizontal septum has been described conveying nerves and vessels to the nipple areola complex. Methods During the surgical dissection of the lower part of the breast, in supero-medial technique for breast reduction operations, a fascial septum between the lower two quadrants was detected. This fibrous septum was studied through anatomic dissection of breast tissues during routine breast reshaping procedures that was done on 30 female patients. Magnetic resonance imaging (MRI) was performed preoperatively in all cases and correlated with the intraoperative findings. In the other five cases, outside the clinical study, the imaging was done during routine investigation for breast swellings. Results A vertical septum was identified in the lower part of the breast, lying at the breast meridian between the two lower quadrants. It is a tough bi-laminated structure that extends from the middle of the infra-mammary crease caudally to nipple-areola complex cranially and from the pectoral fascia posteriorly to the overlying skin anteriorly. This was proved by MRI findings. Conclusions This study describes a new inferior vertical septum which separates the lower half of the breast into two definite anatomical compartments: medial and lateral.

Role of protease inhibitors and acylation stimulating protein in the adipogenesis in 3T3-L1 cells

Mohamed Mohamed Soliman,Yakut Abdel-Fattah El-Senosi,Maysara Mahmoud Salem,Omniya Mahmoud Abdel Hamid,Kimura Kazuhiro 대한수의학회 2009 JOURNAL OF VETERINARY SCIENCE Vol.10 No.3

Treatment of AIDS (HIV) and hepatitis C virus needs protease inhibitors (PI) to prevent viral replication. Uses of PI in therapy are usually associated with a decrease in body weight and dyslipidemia. Acylation stimulating protein (ASP) is a protein synthesized in adipocytes to increase triglycerides biosynthesis, for that the relation of PI and ASP to adipogenesis is tested in this work. ASP expression was increased during 3T3-L1 differentiation and reached a peak at day 8 with cell maturation. Addition of PI during adipocytes differentiation dose dependently and significantly (p < 0.5) inhibited the degree of triglycerides (TG) accumulation. Moreover, presence of ASP (450 ng/mL) in media significantly (p < 0.5) stimulated the degree of TG accumulation and there was additive stimulation for ASP when added with insulin (10 μg/mL). Finally, when ASP in different doses (Low, 16.7; Medium, 45 and High, 450 ng/mL) incubated with a dose of ×150 PI, ASP partially inhibited the PI-inhibited adipogenesis and TG accumulation. The results in this study show that PI inhibit lipids accumulation and confirm role of ASP in TG biosynthesis and adipogenesis.

Synergistic impact of multiwalled carbon nanotubes on the properties of Ni-Mo thin-film via electrodeposition technique

Mona Hasan Gomaa,Zeinab Abdel Hamid,Magdy Ahmed Mahmoud Ibrahim,Rania Abd El Sttar,El-Said Helmy El- Mosallamy 한국화학공학회 2023 Korean Journal of Chemical Engineering Vol.40 No.5

Carbon nanotubes (CNTs) are the hardest and strongest materials due to their perfect mechanical properties and excellent chemical, electrical, and thermal characteristics. Therefore, CNTs are attractive candidates for the development of innovative multifunctional nanocomposites. The goal of the study was to synthesize and characterize NiMoCNT nanocomposite coatings onto steel substrates by electrodeposition technique to enhance the properties of the NiMo layer coating. The electrodeposition was carried out galvanostatically, and the percentage of MWCNT (wt%) in the composites was investigated under various working circumstances, including current density, pH, temperature, and CNTs concentration in the electroplating bath. Different techniques, such as X-ray diffraction (XRD), X-ray photoelectron spectroscopy (XPS), and energy dispersive X-ray analysis (EDS), were used for the composite characterization. Moreover, the corrosion resistance and the nanocomposites’ mechanical characteristics were investigated. The results of the NiMo alloy show that the enhancement in current density decreases the Mo content from 41.8 wt% (at 3.5×10−2 Acm−2) to 31.06 wt% (at 6.5×10−2 Acm−2). On the other hand, the results proved that as the concentration of CNTs in the bath increases, the wt% of CNTs co-deposited in the NiMo matrix enhances, peaking at 22.36 wt% at 0.03 gL−1. Furthermore, the findings show that the Mo content of the coating is reduced when CNTs are present. In comparison to a NiMo coating without CNTs, the composite incorporating CNTs exhibits better corrosion resistance. In addition, the mechanical properties show that the microhardness of NiMoCNT composite-coated steel is better than that of NiMo, and the highest microhardness of NiMoCNT composite coated steel was 4.69 GPa, while pure NiMo coated steel had a microhardness of 2.37 GPa.

Voltammetric Studies of Cu-Adriblastina Complex and Its Effect on ssDNA-Adriblastina Interaction at In Situ Mercury Film Electrode

D. Abd El-Hady,M. Ibrahim Abdel-Hamid,M. Mahmoud Seliem,N. Abo E-Maali 대한약학회 2004 Archives of Pharmacal Research Vol.27 No.11

Adriblastina, a cancerostatic anthracycline antibiotic, causes considerable oxidative damage to DNA molecules. The interaction of this compound with DNA was investigated using Osteryoung square wave stripping voltammetry (OSWSV) and cyclic voltammetry (CV) at an in situ mercury film electrode. It was found that the equilibrium constant of the bonded oxidized form of the drug was 63 times bigger more important than that of the bonded reduced form. Copper forms 1 metal: 2 drug stoichiometry complex which is highly stable compared to ssDNA-drug interaction and consequently inhibited the drug biochemical damaging effects. Copper complex offered sub-nanogram determination of adriblastina in aqueous and urine media.

Antioxidant and antibacterial activities of bioactive peptides in buffalo’s yoghurt fermented with different starter cultures

Soad Taha,Moniur El Abd,Cristian De Gobba,Mahmoud Abdel-Hamid,Ensaf Khalil,Doaa Hassan 한국식품과학회 2017 Food Science and Biotechnology Vol.26 No.5

The effect of Lactobacillus acidophilus 20552 ATCC (T2) or Lactobacillus helveticus CH 5 (T3) in combination with yoghurt starter (1:1) on the antioxidant and antibacterial activities of the bioactive peptides present in buffalo’s yoghurt was studied. The SDS-PAGE results indicate that all caseins were completely hydrolyzed by both strains, whereas whey protein fractions were still present. All starter cultures have the ability to produce lowmolecular- weight bioactive peptides, most of which were originated from b-casein and fewer from as1 casein. The antioxidant activity (%) of the water-soluble peptide extract from yoghurt samples increased in all samples during storage. Samples containing Lb. helveticus CH 5 showed the highest values. All yoghurt treatments displayed antibacterial activity against Escherichia coli. Control yoghurt and T3 showed higher antibacterial activity on E. coli, Staphylococcus aureus, and Bacillus cereus as compared to T2.