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Characterization of Phage Behaviors Against Antibiotic-Resistant Salmonella Typhimurium
Maheswaran Easwaran,Juhee Ahn 한국식품위생안전성학회 2020 한국식품위생안전성학회지 Vol.35 No.6
본 연구는 다양한 항생제 내성을 갖는 Salmonella enterica subsp. enterica serovar Typhimurium ATCC 19585 (STWT), S. Typhimurium KCCM 40253 (STKCCM), ciprofloxacininduced S. Typhimurium ATCC 19585 strains (STCIP), and S. Typhimurium CCARM 8009 (STCCARM)에 대한 phage의 흡착 및 용균 특성을 평가하였다. PBST-10, PBST-13, PBST-32, PBST-35, P-22, P-22 B1 phages는 narrow host range를 보였다. 숙주인 STWT, STKCCM, STCIP에 대한 phage 의 흡착률은 각각 47-85%, 58-95%, 61-93%였지만, STCCARM 에 대한 phage의 흡착률은 14-36%의 낮은 수준을 보였다. STWT, STKCCM, STCIP, STCCARM에 대한 phage burst size는 각 각 43-350, 37-530, 66-500, 24-500 plaque-forming unit (PFU)으로 다양하게 관찰되었다. P-22 B1을 제외한 모든 phage는 배양 초기에 STCIP숙주를 효과적으로 저해하였다. 이러한 결과는 항생제 내성균을 저해하기 위해 phage control system 개발에 유용한 정보로 활용될 것이다. This study was designed to investigate the dynamic behaviors of phages against Salmonella enterica subsp. enterica serovar Typhimurium ATCC 19585 (STWT), S. Typhimurium KCCM 40253 (STKCCM), ciprofloxacin- induced S. Typhimurium ATCC 19585 strains (STCIP), and S. Typhimurium CCARM 8009 (STCCARM). Phages, including PBST-10, PBST-13, PBST-32, PBST-35, P-22, and P-22 B1 had narrow host ranges. The adsorption rates of all phages ranged from 47 to 85%, 58 to 95%, and 61 to 93%, respectively, against STWT, STKCCM, and STCIP, while the lowest adsorption rates ranged from 14 to 36% against STCCARM. The phage burst sizes were from 43 to 350, 37 to 530, 66 to 500, and 24 to 500 plaque-forming units (PFUs) per infected STWT, STKCCM, STCIP, and STCCARM, respectively. The STCIP strain was effectively inhibited by all phages at the early of incubation period. These results provide useful information for better understanding the phage behaviors against antibiotic-resistant and antibiotic-sensitive pathogens.
Maheswaran, D.,Rajasekar, N.,Priya, K.,Ashok kumar, L. The Korean Institute of Electrical Engineers 2015 Journal of Electrical Engineering & Technology Vol.10 No.3
Pulse Width Modulation (PWM) techniques are increasingly employed for PWM inverter fed induction motor drive. Among various popular PWM methods used, Selective Harmonic Elimination PWM (SHEPWM) has been widely accepted for its better harmonic elimination capability. In addition, using SHEPWM, it is also possible to maintain better voltage regulation. Hence, in this paper, an attempt has been made to apply Bacterial Foraging Algorithm (BFA) for solving selective harmonic elimination problem. The problem of voltage harmonic elimination together with output voltage regulation is drafted as an optimization task and the solution is sought through proposed method. For performance comparison of BFA, the results obtained are compared with other techniques such as derivative based Newton-Raphson method, and Genetic Algorithm. From the comparison, it can be observed that BFA based approach yields better results. Further, it provides superior convergence, reduced computational burden, and guaranteed global optima. The simulation results are validated through experimental findings.
Behavior of GGBS concrete with pond ash as a partial replacement for sand
Maheswaran, J.,Chellapandian, M.,Kumar, V. Techno-Press 2022 Advances in concrete construction Vol.13 No.3
An attempt is made to develop an eco-friendly concrete with ground granulated blast furnace slag (GGBS) and pond ash as partial replacement materials for cement and fine aggregate, respectively without compromising the strength and durability. Sixteen concrete mixes were developed by replacing cement and fine aggregate by GGBS and pond ash, respectively in stages of 10%. The maximum replacement levels of cement and fine aggregates were 50% and 30% respectively. Experimental results revealed that the optimum percentage of GGBS and pond ash replacement levels were 30% and 20% respectively. The optimized mix was used further to study the flexural behavior and durability properties. Reinforced Concrete (RC) beams were cast and tested under a four-point bending configuration. Also, the specimens prepared from the optimized mix were subjected to alternate wet and dry cycles of acid (3.5% HCl and H<sub>2</sub>SO<sub>4</sub>) and sulphate (10% MgSO<sub>4</sub>) solutions. Results show that the optimized concrete mix with GGBS and pond ash had a negligible weight loss and strength reduction.
Assisting children with special needs
( Nithya Maheswaran ) 대구대학교 한국특수교육문제연구소 2018 한국특수교육문제연구소 학술대회발표자료집 Vol.2018 No.1
When considering assisting children with special needs, there are several important factors that need to be attended to, in order to have a successful impact on the child’s progress. When considering a controlled environment such as a school, the importance of thorough assessment of the child should be emphasized. Every child has unique needs and it is our role as an educator to be able to identify the specific needs and be able to incorporate that within the plan of study and training that the child will receive. Likewise, parental training is something that has equal impact on the child’s progress and is often a common subject that is overlooked by several educators. It is crucial to realize that the child spends more than 75% of the day away from school, and therefore in order to be able to see visible progress, the child should be constantly exposed to a learning environment. I will be discussing both these factors in detail using case studies from my institution, and will attempt to highlight the importance of thorough assessment and parental training when considering the education of a special child.
D. Maheswaran,N. Rajasekar,K. Priya,L. Ashok kumar 대한전기학회 2015 Journal of Electrical Engineering & Technology Vol.10 No.3
Pulse Width Modulation (PWM) techniques are increasingly employed for PWM inverter fed induction motor drive. Among various popular PWM methods used, Selective Harmonic Elimination PWM (SHEPWM) has been widely accepted for its better harmonic elimination capability. In addition, using SHEPWM, it is also possible to maintain better voltage regulation. Hence, in this paper, an attempt has been made to apply Bacterial Foraging Algorithm (BFA) for solving selective harmonic elimination problem. The problem of voltage harmonic elimination together with output voltage regulation is drafted as an optimization task and the solution is sought through proposed method. For performance comparison of BFA, the results obtained are compared with other techniques such as derivative based Newton-Raphson method, and Genetic Algorithm. From the comparison, it can be observed that BFA based approach yields better results. Further, it provides superior convergence, reduced computational burden, and guaranteed global optima. The simulation results are validated through experimental findings.
C.P. Maheswaran,C. Helen Sulochana 한국통신학회 2016 ICT Express Vol.2 No.2
With respect to the rapidly growing Fourth Generation (4G) wireless communication system, an outstanding feature is the heterogeneous wireless access. Despite the fact that this amazing feature allows users to connect to several wireless access networks simultaneously, various challenges with respect to bandwidth allocation (BA) among various heterogeneous networks also arise. A feasible and effective solution to tackle this problem has been proposed in this paper, which concerns a bandwidth allocation using game (BAG) algorithm with respect to heterogeneous wireless networks. This paper proposes modeling a Resource allocation RA or Bandwidth Allocation problem as a game, and then formulating it to increase the total utility to a maximum of the dissimilar networks. The game model that has been proposed in this paper also establishes the existence of the Experimental Economic Method (EEM). In order to divert assigning too much Resource or bandwidth to a single user, utility functions have also been designed. Moreover, simulation results reveal that the scheme proposed in this paper not only achieves a high utility, but also reduces blocking probability within a few iterations.