Prenatal exposure to phencyclidine produces abnormal behaviour and NMDA receptor expression in postpubertal mice

Lu, Lingling,Mamiya, Takayoshi,Lu, Ping,Toriumi, Kazuya,Mouri, Akihiro,Hiramatsu, Masayuki,Kim, Hyoung-Chun,Zou, Li-Bo,Nagai, Taku,Nabeshima, Toshitaka Oxford University Press 2010 International Journal of Neuropsychopharmacology Vol.13 No.7

HOW CHINESE CONSUMERS RESPONSE TO FOOD NUTRITION CLAIM

Jingwen Liu,Peng Zou,Qingqing Lu 글로벌지식마케팅경영학회 2016 Global Marketing Conference Vol.2016 No.7

With increasing income and education, requirements to product quality are getting higher in China. Specifically, people tend to nutrition and health now. Food safety has attracted increasing attention due to its importance. The nutrition claims on packaging became one of the most important standards to decide whether to buy. A great deal of research has focused on consumer responses (e.g., Hieke and Taylor 2012; Parker & Lehmann 2014; Shah et al. 2014) to the influx of product information to markets. Topics of research included the impact on consumers’ beliefs with regards to products (Ford et al. 2005), purchasing behavior (Nikolova and Inman 2015), and information processing behavior (Moorman 1990). The diversity of consumer responses is based on consumer differences (Moorman 1990), and health- and nutrition-related (HNR) claims (Choi et al. 2013). Although a great deal of research has addressed the influence of product information disclosure on the market, these studies have focused almost exclusively on developed economies. Going forward it is very likely that emerging markets will play a more important part in corporate strategic planning, as opposed to something considered after making plans for long developed markets. Thus, the impact of market information is likely to matter more and more to those global marketers operating in emerging markets. To fill the research gaps, we investigated how the existence and forms of nutrition claims affect the purchase intention of consumers in China. We explore the moderating role of consumer’s nutrition knowledge. We combine simulation experiment and questionnaire and design two experiments: Experiment 1 is about the existence of nutrition claims, we want to know how the existence of nutrition claims affects the purchase intention of consumers. Experiment 2 which is 2(health claims Vs function claims)×2 (promotion Vs prevention) test is to find out how the claim presentation forms impact the purchase intention of consumers. In experiment 1, we required the subjects to choose one setting randomly and fill in the questionnaires according to their choices. We collected 315 effective questionnaires of experiment 1and 156 effective questionnaires of experiment 2. The results show that: (1) The existence of nutrition claims affects the purchase intention of consumers. specifically, compared with the product without health claims, consumers tend to choose the one with health claims, and compared with the product without function claims, consumers tend to choose the one with health claims.(2)Nutrition knowledge plays a positively role. Nutrition knowledge can change the effect of the existence of health claims and function claims on purchase intention.(3) Consumer trust only plays a partly moderate role. The consumer trust can increase the effect of the existence of function claims but not health claims on purchase intention.(4)The forms of nutrition claims affect consumers purchase intention. Consumers tend to choose the product with promotion claims more than the one with prevention claims.(5) Nutrition knowledge plays a positively role, it can improve the effect of the forms of health claims on purchase intention. The more nutritional knowledge does consumers comprehend, the more sensitive to the product with promotion claims they are.(6)Consumer trust also plays a positively role. The higher Consumer trust does consumers maintain, the more sensitive to the product with promotion claims they are.

Characterization of the complete chloroplast genome sequence of <i>Hypericum petiolulatum</i> (Hypericaceae)

ZOU Le,BAI Rui-Zhu,XIANG Chun-Lei,LI Lu 한국식물분류학회 2024 식물 분류학회지 Vol.54 No.1

<i>Hypericum</i> L. (Hypericaceae) is one of the best-selling herbal medicines in the world comprising ca. 500 species of herbs, shrubs, and small trees. <i>Hypericum petiolulatum</i> Hook. f. & Thomson ex Dyer is widely distributed in China, Vietnam, Myanmar, Nepal, India, Malaysia, and Bhutan and is used as a traditional herb to treat hemoptysis and inflammation. In this study, we sequenced and assembled the complete chloroplast (cp) genome of <i>H. petiolulatum</i>. The complete plastome of <i>H. petiolulatum</i> was 136,105 bp in length, with a large single copy region (LSC) of 93,709 bp, a small single copy region (SSC) of 11088 bp and two identical inverted repeats (IRs) of 15,654 bp. The overall GC content of the plastome was 37.0%, while GC contents of the LSC, SSC, and each IR were 35.5%, 31.0%, and 43.8%, respectively. In addition, 116 genes consisting of 76 protein-coding genes, six ribosomal RNA genes, and 34 transfer RNA genes were identified. A phylogenetic analysis of 14 taxa inferred based on cp genome sequences revealed a close relationship between <i>H. petiolulatum</i> and <i>H. perforatum</i>. The complete cp genome sequence of <i>H. petiolulatum</i> reported in this paper will facilitate population and phylogenomics studies of this medicinal plant group.

Shape Recognition and Classification Based on Poisson Equation- Fourier-Mellin Moment Descriptor

Zou, Jian-Cheng,Ke, Nan-Nan,Lu, Yan Society for Computational Design and Engineering 2008 International Journal of CAD/CAM Vol.8 No.1

In this paper, we present a new shape descriptor, which is named Poisson equation-Fourier-Mellin moment Descriptor. We solve the Poisson equation in the shape area, and use the solution to get feature function, which are then integrated using Fourier-Mellin moment to represent the shape. This method develops the Poisson equation-geometric moment Descriptor proposed by Lena Gorelick, and keeps both advantages of Poisson equation-geometric moment and Fourier-Mellin moment. It is proved better than Poisson equation-geometric moment Descriptor in shape recognition and classification experiments.

Regular Unknown Input Functional Observers for 2-D Singular Systems

Lu Wang,Huiling Xu,Yun Zou 제어·로봇·시스템학회 2013 International Journal of Control, Automation, and Vol.11 No.5

This paper concerns with asymptotic regular unknown input functional observers (UIFOs) for two-dimensional (2-D) acceptable singular systems described by the Fornasini-Marchesini local state-space second model. A sufficient condition for the existence of an asymptotic regular UIFO is first presented in terms of a rank condition on the given system matrices. Based on this, an asymptotic 2-D regular UIFO is constructed using a linear matrix inequality (LMI) technique, while a new method is also given for designing regular functional observers for 2-D acceptable singular systems. Two illustrative examples are provided to demonstrate the feasibility and effectiveness of the proposed method.

Engineered exosomes enriched in netrin-1 modRNA promote axonal growth in spinal cord injury by attenuating inflammation and pyroptosis

Lu Xiao,Xu Guangyu,Lin Zhidi,Zou Fei,Liu Siyang,Zhang Yuxuan,Fu Wei,Jiang Jianyuan,Ma Xiaosheng,Song Jian 한국생체재료학회 2023 생체재료학회지 Vol.27 No.00

Spinal cord injury (SCI) brings a heavy burden to individuals and society, and there is no effective treatment at present. Exosomes (EX) are cell secreted vesicles containing molecules such as nucleic acids and proteins, which hold promise for the treatment of SCI. Netrin-1 is an axon guidance factor that regulates neuronal growth. We investigated the effects of engineered EX enriched in netrin-1 chemically synthetic modified message RNA (modRNA) in treating SCI in an attempt to find a novel therapeutic approach for SCI.Netrin-1 modRNA was transfected into bone marrow mesenchymal stem cells to obtain EX enriched with netrin-1 (EX-netrin1). We built an inflammatory model in vitro with lipopolysaccharide (LPS) in vitro to study the therapeutic effect of EX-netrin1 on SCI. For experiments in vitro, ELISA, CCK-8 assay, immunofluorescence staining, lactate dehydrogenase release experiments test, real-time quantitative polymerase chain reaction, and western blot were conducted. At the same time, we constructed a rat model of SCI. MRI, hematoxylin-eosin and Nissl staining were used to assess the extent of SCI in rats.In vitro experiments showed that EX had no effect on the viability of oligodendrocytes and PC12 cells. EX-netrin1 could attenuate LPS-induced inflammation and pyroptosis and accelerate axonal/dentritic growth in PC12 cells/oligodendrocytes. In addition, netrin-1 could activate the PI3K/AKT/mTOR signalling pathway upon binding to its receptor unc5b. When Unc5b and PI3K were inhibited, the effect of EX-netrin1 was weakened, which could be reversed by PI3K or mTOR activator. Our in vivo experiments indicated that EX-netrin1 could promote recovery in rats with SCI.We found that EX-netrin1 regulated inflammation, pyroptosis and axon growth in SCI via the Unc5b/PI3K/AKT/mTOR pathway, which provides a new strategy for the treatment of SCI.

Research on Improving Memory of VR Game based on Visual Thinking

Kai Lu,조동민,Jia Xing Zou 한국멀티미디어학회 2022 멀티미디어학회논문지 Vol.25 No.5

Based on visual Thinking theory, VR(virtual reality) game changes the traditional form of memory and maps the content into game elements to realize the immersive spatial memory mode. This paper analyzes the influencing factors of game design and system function construction. This paper proposes a hypothesis: with the help of visual thinking theory, VR game is helpful to improve learners' visual memory, and carries out research. The experiment sets different levels of game through empirical research and case analysis of memory flip game. For example, when judging two random cards. If the pictures are the same, it will be judged as the correct combination; if they are different, the two cards will be restored to the original state. The results are analyzed by descriptive statistical analysis and AMOS data analysis. The results show that game content using the concept of "Memory Palace", which can improve the accuracy of memory. We conclude that the use of spatial localization characteristics in flip games combining visual thinking can improve users' memory by helping users memorize and organize information in a Virtual environment, which means VR games have strong feasibility and effectiveness in improving memory.

A novel pattern recognition protein of the Chinese oak silkmoth, Antheraea pernyi, is involved in the pro-PO activating system

Xia Lu Wan,Zhang Jing Hai,Ying Chen,You Lei Ma,Wen Jun Zou,Guo Yuan Ding,Wei Li,Ming Yi Zhao,Chun Fu Wu 생화학분자생물학회(구 한국생화학분자생물학회) 2013 BMB Reports Vol.46 No.7

Influences on Distribution of Solute Atoms in Cu‑8Fe Alloy Solidification Process Under Rotating Magnetic Field

Jin Zou,Qi‑Jie Zhai,Fang‑Yu Liu,Ke‑Ming Liu,De‑Ping Lu 대한금속·재료학회 2018 METALS AND MATERIALS International Vol.24 No.6

A rotating magnetic field (RMF) was applied in the solidification process of Cu-8Fe alloy. Focus on the mechanism of RMFon the solid solution Fe(Cu) atoms in Cu-8Fe alloy, the influences of RMF on solidification structure, solute distribution, andmaterial properties were discussed. Results show that the solidification behavior of Cu–Fe alloy have influenced through thechange of temperature and solute fields in the presence of an applied RMF. The Fe dendrites were refined and transformed torosettes or spherical grains under forced convection. The solute distribution in Cu-rich phase and Fe-rich phase were changedbecause of the variation of the supercooling degree and the solidification rate. Further, the variation in solute distributionwas impacted the strengthening mechanism and conductive mechanism of the material.

Flexural Behavior of Ultra-High Performance Concrete (UHPC) Deck with Joints subjected to an Improved Steel Wire Mesh (SWM) Treatment

Kaiwei Lu,Linpu Du,Fan Zhang,Xingxing Zou,Jingquan Wang 대한토목학회 2023 KSCE Journal of Civil Engineering Vol.27 No.5

Prefabricated Ultra-high performance concrete (UHPC) decks are often connected using UHPC wet joints to create the overall deck structure. The UHPC deck is, nevertheless, made weak by the fiber discontinuity at the contact interface. In this study, the fiber at the interface was made to serve as a bridge using an embedded steel wire mesh, and experiments were utilized to determine how the contact between the fiber and the steel bar affects the flexural behavior. The results show that the fiber significantly affects the ductility and flexural strength without reinforcement. The combined action of the fiber and reinforcement of the reinforced specimen somewhat increases the flexural capacity and ductility. The flexural capacity of decks with joints was finally calculated using three different ways, and it was found that the method that simplifies the tension and compression zones into rectangles is the most appropriate.