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Deep Learning: High-quality Imaging through Multicore Fiber
Liqing Wu,Jun Zhao,Minghai Zhang,Yanzhu Zhang,Xiaoyan Wang,Ziyang Chen,Jixiong Pu 한국광학회 2020 Current Optics and Photonics Vol.4 No.4
Imaging through multicore fiber (MCF) is of great significance in the biomedical domain. Although several techniques have been developed to image an object from a signal passing through MCF, these methods are strongly dependent on the surroundings, such as vibration and the temperature fluctuation of the fiber’s environment. In this paper, we apply a new, strong technique called deep learning to reconstruct the phase image through a MCF in which each core is multimode. To evaluate the network, we employ the binary cross-entropy as the loss function of a convolutional neural network (CNN) with improved U-net structure. The high-quality reconstruction of input objects upon spatial light modulation (SLM) can be realized from the speckle patterns of intensity that contain the information about the objects. Moreover, we study the effect of MCF length on image recovery. It is shown that the shorter the fiber, the better the imaging quality. Based on our findings, MCF may have applications in fields such as endoscopic imaging and optical communication.
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Wenjing Wang,Biao Wu,Zhihong Liu,Liqing Zhou,Xiujun Sun,Jiteng Tian,Aiguo Yang 한국유전학회 2021 Genes & Genomics Vol.43 No.6
Background The ark shell (Scapharca broughtonii) is one of the most economically important mollusks in the Bohai Sea and Yellow Sea of China. In recent years, ark shells from the Korean population were introduced to China for seed propagation and culture. Objective To explore the impact of the introduction of Korean ark shell on the genetic diversity of native population in China. Methods Simple sequence repeat (SSR) is efective and widely used tool for genetic analysis. In this study, 180 EST-SSRs were selected and verifed by polymerase chain reaction and polyacrylamide gel electrophoresis. Subsequently, fve polymorphic EST-SSRs were screened and their primers were modifed by fuorescein for use in the genetic analysis of four populations. Results Genetic analysis showed that 361 alleles amplifed by fve SSR loci were detected in the four populations. The number of alleles for the fve SSRs ranged from 8 to 30, with a mean of 18.05 (standard deviation, SD=6.492). The efective number of alleles varied from 2.253 to 22.222, with a mean of 10.596 (SD=4.713). Observed heterozygosity and expected heterozygosity were 0.167–0.833 and 0.566–0.971, with average values of 0.520 (SD=0.177) and 0.891 (SD =0.062), respectively. Polymorphic information content ranged from 0.521 to 0.953, with a mean of 0.865 (SD=0.070). The pairwise genetic diferentiation coefcient (FST) of the four populations ranged from 0.0267 to 0.0477, showing low genetic diferentiation. The phylogenetic tree constructed by neighbor-joining method showed that the genetic distance between the Chinese Dalian native population and three Korean populations was relatively more far than that among those Korean populations. Conclusion The results indicated that the genetic structure of the Dalian wild population was less afected by the introduced Korean wild populations.
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Hongguan Wang,Guofeng Qiu,Yanjie Niu,Liqing Chen,Yan Li,Sixi Guo,Yixin Zhang,Jianjun Wu,Fanhui Guo 한국공업화학회 2023 Journal of Industrial and Engineering Chemistry Vol.125 No.-
Spent tire is a kind of solid waste with large production, accumulation and great pollution. Spent tire charis the primary product of tire harmless disposal. Its commercial value is enhanced by modification. In thisstudy, K-N co-doped activated carbon was prepared by using spent tire char as raw material, KOH andmelamine as activator and dopant to enhance CO2 capture. In comparison with traditional process, thereasons for the decrease in specific surface area and pore volume caused by K doped have been identified,and a potential doped mechanism has been proposed. It was determined that pyridine nitrogen in theamino functional group played a key role in CO2 adsorption. Meanwhile, the synergistic intensificationof CO2 adsorption by potassium phenolic and pyridine nitrogen was verified by simplified model simulation. The precise K-N doping significantly intensify the CO2 adsorption capacity of spent tire char from0.45 to 2.60 mmol/g (1 bar, 0℃), an increase of 4.78 times. Thermodynamic studies have demonstratedthat the Langmuir model accurately describes the adsorption process, and the adsorption reaction takesplace spontaneously at temperatures below 80.52 C. This work presents an efficient process for upgradingspent tire char, and a novel method of co-treating waste and CO2.
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Fanhui Guo,Sixi Guo,Yanjie Niu,Guofeng Qiu,Yang Guo,Yan Li,Liqing Chen,Yixin Zhang,Jianjun Wu 한국공업화학회 2023 Journal of Industrial and Engineering Chemistry Vol.125 No.-
Porous carbon materials with ultra-high specific surface area and adjustable pore structure characteristicswere prepared from food industry waste hazelnut shells for the adsorption of methylene blue (MB)wastewater by two-step activation by impregnation with ZnCl2 followed by chemical activation withKOH. The Fusso effect, which can reduce the size of MB molecules, was further used to enhance theadsorption of MB on porous carbon. The results show that both HSBC-a and HSBC-a-b have ultra-highspecific surface area (2979.59 m2/g for HSBC-a, 2882.73 m2/g for HSBC-a-b). The mesopore ratio ofHSBC-a-b (Vmeso/Vtotal % = 14.05%) was doubled compared to HSBC-a. It showed an excellent adsorptionperformance of 694.03 mg/g for MB. It showed a fast adsorption kinetics and the adsorbed amountincreased to 882.46 mg/g at 0.1 M NaCl solution. In addition, adsorption processes were studied usingadsorption kinetics and adsorption isotherm model fitting. The results of this research confirm that hazelnutshell is a kind of promising and sustainable porous carbon raw material, and its ultra-high specificsurface area and adjustable pore structure characteristics are favorable for the efficient treatment ofMB from dyeing wastewater. This work could provide potential guidance for the high-value utilizationof waste hazelnut shell biochar.
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Rui Zou,Xiao Zhou,Hailing Liu,Peng Wang,Fan Xia,Liqing Kang,Lei Yu,Depei Wu,Zhengming Jin,Changju Qu 대한암학회 2023 Cancer Research and Treatment Vol.55 No.4
Primary central nervous system lymphoma (PCNSL) is a rare and aggressive non-Hodgkin’s lymphoma that affects the brain, eyes, cerebrospinal fluid, or spinal cord without systemic involvement. The outcome of patients with PCNSL is worse compared to patients with systemic diffuse large B-cell lymphoma. Given potential mortality associated with severe immune effector cell-associated neurotoxicity syndrome (ICANS), patients with PCNSL have been excluded from most clinical trials involving chimeric antigen receptor T-cell (CAR-T) therapy initially. Here, we report for the first time to apply decitabine-primed tandem CD19/CD22 dual-targeted CAR-T therapy with programmed cell death-1 (PD-1) and Bruton’s tyrosine kinase (BTK) inhibitors maintenance in one patient with multiline-resistant refractory PCNSL and the patient has maintained complete remission (CR) for a 35-month follow-up period. This case represents the first successful treatment of multiline resistant refractory PCNSL with long-term CR and without inducing ICANS under tandem CD19/CD22 bispecific CAR-T therapy followed by maintenance therapy with PD-1 and BTK inhibitors. This study shows tremendous potential in the treatment of PCNSL and offers a look toward ongoing clinical studies.
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