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- 저자 : Liqing Tang (검색결과 3 건)
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Liqing Tang,Tongyun Zhang HONG KONG ACADEMY OF SOCIAL SCIENCES 2023 Journal of Social Science Development Research Vol.1 No.1
With the advancement of economic globalization and the gradual intensification of competition in international market, enterprises need to constantly enhance their comprehensive strength to consolidate market position and improve the internal innovation ability, which is also a new mission given to enterprises under the new era. At present, the innovation activities of Chinese enterprises are faced with many difficulties, such as long investment cycle time, too much investment capital, high risk, short-term income is not obvious, and so on. However, if enterprises use agents to promote enterprise innovation, the financing constraints caused by the current market agency costs and internal and external information asymmetry greatly hinder the process of independent innovation of private enterprises. Therefore, it is of great significance to study the influencing factors of private enterprises' input in indigenous innovation to improve their independent innovation ability and promote their further development.
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Seismic Response of Resilient Steel Frame with Self-Centering SMA Brace
Shujun Hu,Liqing Chang,Bo Zhang,Sizhi Zeng,Fenghua Tang,Qing Zhi 한국강구조학회 2023 International Journal of Steel Structures Vol.23 No.6
An innovative self-centering shape memory alloy (SMA) brace aiming at improving the seismic performance and self-centering capacity of steel frame structures is proposed in this paper. A series of cyclic loading tests with six self-centering SMA brace (SC-SMAB) specimens was carried out to investigate the effects of SMA area, bolt torque and initial SMA force on the hysteresis curves, energy dissipation and self-centering capacity. In addition, based on the experimental results, a numerical model of SC-SMAB with the improved Graesser and Bouc–Wen model was established and validated. Three different single-bay plan configurations of 9 storey steel frames including bare steel frame (BSF), steel frame with slip braces (SF-SB) and steel frame with SC-SMABs (SF-SCB) were analyzed to evaluate the seismic response. The test results show that the SC-SMAB with the bolt torque of 10 N M and initial SMA force of 5 kN has the maximum bearing force and self-centering capacity ratio. The established numerical model can accurately predict the seismic performance of the SC-SMAB. The inter-story drift ratio, roof displacement and roof acceleration of SF-SCB are lower than those of the BSF and SF-SB evidently, which decrease by 62.21%, 29.46% and 28.36% respectively from BSF. The hysteresis curve of SC-SMAB in the steel frame has nearly ideal flag-shape with high bearing force, good energy dissipation capacity, small residual deformation and outstanding re-centering capacity.
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Chongli Xu,Yu Liu,Yuchen Gong,Xinping Duan,Xiaochun Tang,Mingjun Zhang,Daxin Pang,Liqing Yu,Hongwei Zhao,Hongsheng Ouyang 한국유전학회 2015 Genes & Genomics Vol.37 No.2
Although Niemann-Pick C1-Like 1 (NPC1L1)plays a key role in intestinal cholesterol absorption, regulatingcholesterol metabolism and maintaining cholesterolmetabolic homeostasis, the molecular mechanism ofNPC1L1 in lipid-metabolism disorders leading to liverdisease remains largely unknown. Previous studies haveshown that NPC1L1 is related with the development offatty liver. Therefore, we hypothesized that NPC1L1 playsan important role in lipid-metabolism disorders and liverdisease by affecting the transcription of certain genesinvolved in lipid synthesis. To further elucidate the functionof NPC1L1, especially in the liver, we used somaticcellnuclear transfer to establish transgenic pigs thatexpressed human NPC1L1 in their livers. We investigatedsuperoxide dismutase activities and the levels of free fattyacids and malondialdehyde, a biomarker of lipid peroxidation. Superoxide dismutase activities significantlydecreased, and free fatty acid and malondialdehyde levelssignificantly increased in the NPC1L1 transgenic pigs,indicating that the overexpression of NPC1L1 in the liverresulted in severe lipid peroxidation. Our findings suggestthat NPC1L1 plays an important role in lipid-metabolismdisorders and liver disease.
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