A novel covalent organic framework with multiple adsorption sites for removal of Hg2+ and sensitive detection of nitrofural

Linyu Wang,Yonghai Song,Ying Luo,Li Wang 한국공업화학회 2022 Journal of Industrial and Engineering Chemistry Vol.106 No.-

It is urgent to control serious drug pollution and heavy metal ion pollution. Covalent organic framework(COF) is becoming a promising material for the removal of heavy metal ion and adsorption of organicsmall molecule because of the designed functional sites, ordered pore channel, high specific surface areaand abundant p electrons. Herein, 2,4,6-triformylphloroglucinol (TFP) and benzene-1,3,5-tricarbohydrazide (BTH) was used to design a stable yet efficient beta-ketoenamine COF (COFTFP-BTH)adsorbent, which would provide multiple adsorption sites of Hg2+ by dense acylhydrazine. The maximumadsorption capacity of COFTFP-BTH toward Hg2+ achieved 909 mg g1, coinciding with Langmuir adsorptionand pseudo-second-order adsorption kinetic model, with the h value as high as 71.43 mg g1 min1. COFTFP-BTH was also grown on NH2-carbon nanotubes (CNT) to form a novel COFTFP-BTH@NH2-CNT compositefor sensitive detection of nitrofural (NF). The NF sensor based on COFTFP-BTH@NH2-CNT showed alow detection limit (3.2 nM) and a wide linear range (9.6 nM-100 lM). The excellent performances werealso attributed to the ordered channels of COFTFP-BTH exposing more adsorption sites of Hg2+ and NF, aswell as the good stability of beta-ketoenamine COFTFP-BTH.

Caspase Recruitment Domain Containing Protein 9 Suppresses Non-Small Cell Lung Cancer Proliferation and Invasion via Inhibiting MAPK/p38 Pathway

Linyue Pan,Yuting Tan,Bin Wang,Wenjia Qiu,Yulei Yin,Haiyan Ge,Huili Zhu 대한암학회 2020 Cancer Research and Treatment Vol.52 No.3

Purpose Caspase recruitment domain containing protein 9 (CARD9) has been demonstrated to be a pro-tumor factor in various cancers. However, our previous study found a significant decrease of CARD9 in malignant pleural effusion compared with benign pleural effusion. So we investigated the role of CARD9 in non-small cell lung cancer (NSCLC) and its working mechanism. Materials and Methods Immunohistochemistry, western blot, and quantitative real-time polymerase chain reaction were used to detect the expression of CARD9 in specimens of NSCLC patients. The Cancer Genome Atlas (TCGA) database was also used to analyze the expression of CARD9 in NSCLC and its predicting value for prognosis. Immunofluorescence was used for CARD9 cellular location. Cell growth assay, clonal formation assay, wound healing assay, matrigel invasion assay, and flow cytometry were used to test cell proliferation, migration, invasion, apoptosis, and cycle progression of NSCLC cells with CARD9 knockdown or CARD9 overexpression. Co-immunoprecipitation was used to identify the interaction between CARD9 and B-cell lymphoma 10 (BCL10). SB203580 was used to inhibit p38 activation. Results CARD9 was decreased in NSCLC tissues compared with normal tissues; low CARD9 expression was associated with poor survival. CARD9 was expressed both in tumor cells and macrophages. Downregulation of CARD9 in NSCLC cells enhanced the abilities of proliferation, invasion, and migration via activated mitogen-activated protein kinases (MAPK)/p38 signaling, while overexpression of CARD9 presented antitumor effects. BCL10 was identified to interact with CARD9. Conclusion We demonstrate that CARD9 is an independent prognostic factor in NSCLC patients and inhibits proliferation, migration, and invasion by suppressing MAPK/p38 pathway in NSCLC cells.

Porous WO₃ monolith-based photoanodes for high-efficient photoelectrochemical water splitting

Wang, Yina,Zhang, Fangfang,Zhao, Guoyan,Zhao, Yingao,Ren, Yangyang,Zhang, Huijun,Zhang, Linyu,Du, Jimin,Han, Yumin,Kang, Dae Joon Elsevier 2019 CERAMICS INTERNATIONAL Vol.45 No.6

<P><B>Abstract</B></P> <P>We report a successful fabrication of low-cost, high-efficient, structurally-rigid, porous WO<SUB>3</SUB> photoelectrochemical (PEC) catalysts using polystyrene as the template by a sol-gel method and a high-temperature annealing treatment. The scanning electron microscopy and Brunauer-Emmett-Teller surface analysis results indicate that such WO<SUB>3</SUB> monoliths possess a porous structure and a large specific surface area, which can supply lots of photogenerated charge transfer pathways as well as more surface PEC active sites. Compared with a commercially available WO<SUB>3</SUB>, our highly porous WO<SUB>3</SUB> PEC catalysts show an excellent PEC water splitting activity. Particularly, the porous WO<SUB>3</SUB> photoanodes calcinated in the presence of oxygen atmosphere at 450 °C for 7 h show the best PEC performance exhibiting the photocurrent density of 0.97 mA/cm<SUP>2</SUP> at 1.23 V versus reversible the hydrogen electrode and the incident photon-to-current conversion efficiency up to 48.9% at 420 nm in 0.5 M Na<SUB>2</SUB>SO<SUB>4</SUB> electrolyte under AM 1.5 G irradiation. Such excellent PEC performance is due to the high porosity of the WO<SUB>3</SUB>, promoting the fast transfer and the separation rate of photogenerated carriers during the PEC water splitting process.</P>

Impact of acid-base conditions on defluoridation by induced crystallization

Linyu Deng,Ying Wang,Jianqi Zhou,Ting Lin Huang,Xin Sun 한국공업화학회 2020 Journal of Industrial and Engineering Chemistry Vol.83 No.-

Defluoridation by induced crystallization under extreme pH and bicarbonate/carbonate alkalinity of anaquatic environment was researched. At the conditions of initial pH 4–10 and alkalinity of less than9.92 mM, the F could be successfully removed by the induced crystallization of Ca5(PO4)3F on the PRsurface within 1 h. With a prolonged time of 144 h, the F could be also removed by the formation ofCa5(PO4)3F at initial pH 2 and alkalinity 9.92 mM. However, in extreme base aquatic environments, suchas pH 12 or alkalinity 17.12 mM, the F was partially removed by the induced crystallization of FCO3-apatite (Ca9.316Na0.36Mg0.144(PO4)4.8(CO3)1.2F2.48) and the F could be completely removed by adjustingpH to a range of 4–10. Additionally, the safe disposal of spent crystal seed is successfully achieved as anextra benefit.

Effects of Reaction Conditions on EICP-Treated Desert Aeolian Sand

Linyu Wu,Linchang Miao,Satoru Kawasaki,Hengxing Wang 대한토목학회 2022 KSCE JOURNAL OF CIVIL ENGINEERING Vol.26 No.6

Aeolian sand is a fine, non-cohesive and homogeneous material widely distributed in desert areas, and therefore susceptible to wind erosion, causing serious environmental concerns. This study demonstrates the promise of enzyme-induced carbonate precipitation (EICP) as a means of solidifying aeolian sand to prevent wind erosion. Different cementation solution concentration, urease activity, temperature and number of treatments will have diverse influence on the mechanical property of solidified sand. The test-tube experiments were performed to evaluate the effect of these factors on the enzymatic calcium carbonate precipitation process. The method was then applied to solidify aeolian sand to assess the reinforcement effect by unconfined compressive strength (UCS), calcium carbonate content and mercury intrusion capillary pressure tests. The results demonstrated that the increase of urease activity from 2.95 U/mL to 5.39 U/mL and that of cementation solution from 0.25 M to 0.75 M resulted in an increase in UCS. The increase of number of treatments and that of temperature from 15oC to 45oC can also effectively enhance the mechanical property of aeolian sand. The mercury intrusion capillary pressure test revealed that the improvement of performance of solidified aeolian sand was mainly due to the reduction of porosity caused by the generated of calcium carbonate; and there is an exponential function relationship between the strength and porosity. Furthermore, the increase in urease activity and temperature significantly reduced the porosity and the proportion of larger pores in the solidified sand, thereby appreciably enhancing the strength of aeolian sand with a minor increase in calcium carbonate content.

A Hybrid Life-Cycle Analysis and Two-Stage Stochastic Programming Model for Low-Carbon Management upon Urban Water Resources

Wencong Yue,Yanpeng Cai,Linyu Xu,Xumei Wang,Qiangqiang Rong,Lin Liu 보안공학연구지원센터 2016 International Journal of Smart Home Vol.10 No.6

Due to population growth and economic development, water demands for municipal, industrial, and agricultural users are increasing. It is a challenging and critical issue in water resources system to properly allocate and utilize water resources to satisfy the goals of different stakeholders and greenhouse gases mitigation. In this study, a hybrid life-cycle analysis and two-stage stochastic programming model was proposed to analyze the water-allocation strategies based on complicated urban water resource system. The hybrid model can effectively assess the low-carbon performance of an urban water resources system in the framework of life-cycle analysis. The environmental impacts and GHGs reduction of urban water resources were firstly considered as the objective and constraint for solving the water allocation problems. The results indicated that the first-stage solutions of surface water conveyance of Dalian could be [3.83×108, 8.25×108] in 2015, and [3.83×108, 9.21×108] in 2020; Meanwhile, the first-stage solutions of surface water conveyance of Dalian could be [4.26×108, 8.68×108] in 2015, and [5.35×108, 10.7×108] in 2020.