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      • KCI등재

        Phase transition, ferroelectric and piezoelectric properties of Ba1- xCaxTi1-yZryO3 lead-free ceramics

        Wei Lin,Linli Fan,Dunmin Lin,Qiaoji Zheng,Ximing Fan,Hailing Sun 한국물리학회 2013 Current Applied Physics Vol.13 No.1

        Lead-free piezoelectric ceramics Ba1xCaxTi1yZryO3þ1mol%CuO were prepared by an ordinary sintering technique and the effects of Ca2þ and Zr4þ on phase transition and electrical properties of the ceramics were studied. The results of X-ray diffraction show that the ceramics exhibit a pure perovskite structure at 0 x 0.175 and 0 y 0.175, suggesting that Ca2þ and Zr4þ diffuse into BaTiO3 lattices to form a solid solution. The substitution of Zr4þ for the B-site Ti4þ ions of BaTiO3 decreases greatly Curie temperature TC and strengthens the relaxor character of the ceramics, while the addition of Ca2þ has a weak influence on TC and leads to an inhibition of grain growth. Owing to the more possible polarization states resulting from the coexistence of tetragonal and orthorhombic phases near room temperature, the ceramics with x ¼ 0.075e0.125 and y ¼ 0.1 exhibit excellent piezoelectric properties: d33 ¼ 254e345 pC/N and kp ¼ 38.0e45.2%, respectively.

      • KCI등재

        New Pixel Circuit Compensating Poly-si TFT Threshold-voltage Shift for a Driving AMOLED

        Ching-Lin Fan,Y. Y. Lin,B. S. Lin,J. Y. Chang,C. L. Fan,H. C. Chang 한국물리학회 2010 THE JOURNAL OF THE KOREAN PHYSICAL SOCIETY Vol.56 No.4

        This study presents a novel pixel circuit that uses only n-type low-temperature polycrystallinesilicon (poly-Si) thin-film transistors (LTPS-TFTs) to simplify the fabrication process of activematrix organic light-emitting diode (AMOLED) displays. The proposed pixel circuit consists of five switching TFTs, one driving TFT (DTFT), and two capacitors. The output current and the OLED anode voltage error rates are about 3% and 0.7%, respectively. Thus, the pixel circuit can realize uniform output current with high immunity to the poly-Si TFT threshold voltage deviation. The proposed novel pixel design has great potential for use in large-size, high-resolution AMOLED displays.

      • KCI등재

        A Comparison Study of Sport Medicine Research Trend Before and After the 4th Industrial Revolution: A Systematic Review

        Tenglong Fan(Tenglong Fan),Man-Hsu Lin(Man-Hsu Lin),Kijin Kim(Kijin Kim) 대한운동학회 2023 아시아 운동학 학술지 Vol.25 No.1

        OBJECTIVES The purpose of the study is to explore the changing trend of research keywords in the field of sports medicine the contributions of outstanding authors, institutions, and countries participating in the research, and the technologies directly related to the 4th Industrial Revolution (4IR) in the field of 4IR sports medicine before and after 4IR. METHODS The sample data of this study was retrieved from all the bibliographic information of the top two journals in the sports medicine field (i.e. Sports Medicine and British Journal of Sports Medicine). A bibliometric analysis was carried out by using CiteSpace, and python was used for further text mining on the key nodes in the analysis results. RESULTS The study has found that cardiovascular disease has always been popular in the research field of sports medicine; improving people’s quality of life and avoiding the risk of disease through physical activity, as long as research related to cruciate ligament may appear frequently again in the next few years. After 4IR, the field of sports medicine began to shift from a single study of epidemiology to multidimensional research of epidemiology, preventive medicine and psychology; the population characteristics of the researches began to be more segmented. Also, more collaboration between authors, institutions and institutions involved in sports medicine research has found. Germany and hospitals have become emerging forces after 4IR, and meta-analysis and systematic review are common concerns of Germany and hospitals. The impact of 4IR on sports medicine is mainly manifested in the application of sensors, intelligent monitoring, metabolomics and genomics, which having a great prospect in application. CONCLUSIONS The study sorted out the changes in research trends in the field of sports medicine before and after 4IR, and at the same time proved that the impact of 4IR on sports medicine has already existed, and more scholars need to pay attention. 4IR has brought new forces and new trends to the field of sports medicine, which deepened the research cooperation in this field. Wearable devices, intelligent monitoring, metabolomics, and genomics have applied and had a positive developing trend in sports medicine field.

      • rs10505474 and rs7837328 at 8q24 Cumulatively Confer Risk of Prostate Cancer in Northern Han Chinese

        Zhang, Lin-Lin,Sun, Liang,Zhu, Xiao-Quan,Xu, Yong,Yang, Kuo,Yang, Fan,Yang, Yi-Ge,Chen, Guo-Qiang,Fu, Ji-Cheng,Zheng, Chen-Guang,Li, Ying,Mu, Xiao-Qiu,Shi, Xiao-Hong,Zhao, Fan,Wang, Fei,Yang, Ze,Wang, Asian Pacific Journal of Cancer Prevention 2014 Asian Pacific journal of cancer prevention Vol.15 No.7

        Aims: Genome-wide association studies (GWAS) have identified several risk variants for prostate cancer (pCa) mainly in Europeans, which need to be further verified in other racial groups. We selected six previously identified variants as candidates and to define the association with PCa in Northern Han Chinese. Methods: 749 subjects from Beijing and Tianjin in Northern China were included. Six variants (rs10505474, rs7837328, rs4242384, rs7813, rs486907 and rs1058205) were genotyped by high resolution melting (HRM) assays. The individual and cumulative contribution for of the risk of PCa and clinical covariates were analyzed. Results: Among the six candidate variants, onlyrs10505474, and rs7837328, both locating at 8q24 region, were associated with PCa in our population.rs10505474 (A) was associated with PCa ($OR_{recessive}=1.56$, p=0.006); and rs7837328 (A) was associated with PCa ($OR_{dominant}=1.38$, p=0.042/$OR_{recessive}=1.99$, p=0.003). Moreover, we observed a cumulative effects between them ($p_{trend}=2.58{\times}10^{-5}$). The joint population attributable risk showed the two variants might account for 71.85% of PCa risk. In addition, we found the homozygotes of rs10505474 (A) and rs7837328 (A) were associated with PCa clinical covariants (age at onset, tumor stage, respectively) ($p_{age}=0.046$, $P_{tumorstage}=0.048$). Conclusion: rs10505474 (A) and rs7387328 (A) at 8q24 are associated with PCa and cumulatively confer risk, suggesting the two variations could determine susceptibility to PCa in the Northern Chinese Han population.

      • Encapsulated Egg Deposition Pattern of Schistosoma mansoni in the Peritoneal Cavity of Mice

        Lin, L.L.,Fan, P.C. INSTITUTE OF TROPICAL MEDICINE YONSEI UNIVERSITY 1995 YONSEI REPORTS ON TROPICAL MEDICINE Vol.26 No.1

        Two groups of albino mice were individually exposed to 50 or 300 cercariae of Schistosoma mansoni by intraperitoneal(IP) or percutaneous(PC) route and sacrificed 105-175 days later. The peritoneal cavity was flushed by tap water and worms were perfused by citrate saline solution. The washings were examined with the aid of a dissecting microscope. Mature worms were only found in the protal vein system. The worm recovery rate was higher by percutaneous infection (29.5%) than by intraperitoneal (15.0%). The encapsulated eggs were observed either in the peritoneal cabity or on the intestinal wall; the mean number of encapsulated egg granulomas was also higher in the former (2.5) than in the latter (0.5). The average number of eggs per granuloma was higher by percutaneous infection (2.8) than by intraperitoneal infection (1.2). The mean size of encapsulated egg granulomas was 426 ㎛. There was no viable encapsulated egg granuloma recovered from the intestinal wall while 18% of the eggs from the peritoneal cavity were viable. According to the morphology, the dead encapsulated egg granulomas can be classified as darkened, semi-darkened, with fine granules, and with contracted embryo.

      • KCI등재

        CNOP-Based Sensitive Areas Identification for Tropical Cyclone Adaptive Observations with PCAGA Method

        Lin-Lin Zhang,Shi-Jin Yuan,Bin Mu,Fei-Fan Zhou 한국기상학회 2017 Asia-Pacific Journal of Atmospheric Sciences Vol.53 No.1

        In this paper, conditional nonlinear optimal perturbation (CNOP) was investigated to identify sensitive areas for tropical cyclone adaptive observations with principal component analysis based genetic algorithm (PCAGA) method and two tropical cyclones, Fitow (2013) and Matmo (2014), were studied with a 120 km resolution using the fifth-generation Mesoscale Model (MM5). To verify the effectiveness of PCAGA method, CNOPs were also calculated by an adjoint-based method as a benchmark for comparison on patterns, energies, and vertical distributions of temperatures. Comparing with the benchmark, the CNOPs obtained from PCAGA had similar patterns for Fitow and a little different for Matmo; the vertically integrated energies were located closer to the verification areas and the initial tropical cyclones. Experimental results also presented that the CNOPs of PCAGA had a more positive impact on the forecast improvement, which gained from the reductions of the CNOPs in the whole domain containing sensitive areas. Furthermore, the PCAGA program was executed 40 times for each case and all the averages of benefits were larger than the benchmark. This also proved the validity and stability of the PCAGA method. All results showed that the PCAGA method could approximately solve CNOP of complicated models without computing adjoint models, and obtain more benefits of reducing the CNOPs in the whole domain.

      • KCI등재

        Backbone Cyclization of Flavin Mononucleotide-Based Fluorescent Protein Increases Fluorescence and Stability

        Lin Tingting,Ge Yuanyuan,Gao Qing,Zhang Di,Chen Xiaofeng,Hu Yafang,Fan Jun 한국미생물·생명공학회 2023 Journal of microbiology and biotechnology Vol.33 No.12

        Flavin mononucleotide-binding proteins or domains emit cyan-green fluorescence under aerobic and anaerobic conditions, but relatively low fluorescence and less thermostability limit their application as reporters. In this work, we incorporated the codon-optimized fluorescent protein from Chlamydomonas reinhardtii with two different linkers independently into the redox-responsive split intein construct, overexpressed the precursors in hyperoxic Escherichia coli SHuffle T7 strain, and cyclized the target proteins in vitro in the presence of the reducing agent. Compared with the purified linear protein, the cyclic protein with the short linker displayed enhanced fluorescence. In contrast, cyclized protein with incorporation of the long linker including the myc-tag and human rhinovirus 3C protease cleavable sequence emitted slightly increased fluorescence compared with the protein linearized with the protease cleavage. The cyclic protein with the short linker also exhibited increased thermal stability and exopeptidase resistance. Moreover, induction of the target proteins in an oxygen-deficient culture rendered fluorescent E. coli BL21 (DE3) cells brighter than those overexpressing the linear construct. Thus, the cyclic reporter can hopefully be used in certain thermophilic anaerobes.

      • Amplification at 1400–1450 nm of the Large-Core Nd-Doped Fiber by White LED Pumping

        Lin Htein,Weiwei Fan,Watekar, P. R.,Won-Taek Han IEEE 2013 Photonics Technology Letters Vol.25 No.11

        <P>A novel cost-effective fiber amplifier operating over 1400-1450 nm is developed based on pumping of a large-core Nd-doped fiber with a high-power white light-emitting diode (LED). An optical gain of 6 dB at 1400 nm is obtained by simultaneously exciting the multiple absorption bands in the visible wavelength of the Nd-doped fiber.</P>

      • Impedance Modeling and Stability Analysis of Triple-Phase-Shift-Based Dual Active Bridge Converter with LC Filter

        Fan Feng,Xin Zhang,Peiyi Gao,Fanfan Lin,Bohui Zhao,Hoay Beng Gooi 전력전자학회 2019 ICPE(ISPE)논문집 Vol.2019 No.5

        The emerging triple-phase-shift (TPS) modulation method has been successfully applied to the dual active bridge (DAB) converters, eliminating the circulating current and thus improving the efficiency. Hence the TPS-based DAB converter has been receiving greater attention in recent years. However, the interaction between the TPS-DAB converter and its LC filter may cause instable problems. This paper develops the impedance model of the TPS-DAB converter. With the developed input impedance model, the stability of the TPS-DAB converter and its LC filter is analyzed. The effects of the LC filter parameters on the stability of the TPS-DAB converter and the LC filter are clarified. Finally, the experimental results are provided for validating the impedance model and stability analysis.

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