An Arabidopsis SUMO E3 Ligase, SIZ1, Negatively Regulates Photomorphogenesis by Promoting COP1 Activity

Lin, Xiao-Li,Niu, De,Hu, Zi-Liang,Kim, Dae Heon,Jin, Yin Hua,Cai, Bin,Liu, Peng,Miura, Kenji,Yun, Dae-Jin,Kim, Woe-Yeon,Lin, Rongcheng,Jin, Jing Bo Public Library of Science 2016 PLoS genetics Vol.12 No.4

<P>COP1 (CONSTITUTIVE PHOTOMORPHOGENIC 1), a ubiquitin E3 ligase, is a central negative regulator of photomorphogenesis. However, how COP1 activity is regulated by post-translational modifications remains largely unknown. Here we show that SUMO (small ubiquitin-like modifier) modification enhances COP1 activity. Loss-of-function siz1 mutant seedlings exhibit a weak constitutive photomorphogenic phenotype. SIZ1 physically interacts with COP1 and mediates the sumoylation of COP1. A K193R substitution in COP1 blocks its SUMO modification and reduces COP1 activity in vitro and in planta. Consistently, COP1 activity is reduced in siz1 and the level of HY5, a COP1 target protein, is increased in siz1. Sumoylated COP1 may exhibits higher transubiquitination activity than does non-sumoylated COP1, but SIZ1-mediated SUMO modification does not affect COP1 dimerization, COP1-HY5 interaction, and nuclear accumulation of COP1. Interestingly, prolonged light exposure reduces the sumoylation level of COP1, and COP1 mediates the ubiquitination and degradation of SIZ1. These regulatory mechanisms may maintain the homeostasis of COP1 activity, ensuing proper photomorphogenic development in changing light environment. Our genetic and biochemical studies identify a function for SIZ1 in photomorphogenesis and reveal a novel SUMO-regulated ubiquitin ligase, COP1, in plants.</P>

Research on the influence of union-pay M-payment quality and brand personality on user viscosity

Zi-Yang Liu,Jun-Lin Wang,Jiayu Liu,Xiao-yin Liu,Kai Liao 한국컴퓨터정보학회 2020 韓國컴퓨터情報學會論文誌 Vol.25 No.4

이 연구의 목적은 서비스 품질 및 브랜드 특성의 관점에서 Union-Pay 모바일 결제가 사용자 점도에 미치는 영향을 탐색하는 것이다. 앞으로 중국Union-Pay가 모바일결제 시장에서 안정적이고 충실한 사용자 그룹을 확보하는 것이 의미가 있다. 이 연구는 SPSS22.0 및 AMOS 통계 분석 도구를 사용하여 경험적 연구를 수행을 했다. 본 연구는 모바일 서비스 품질을 사용하고 브랜드 성격은 독립 변수이고, 사용자의 점도는 종속 변수이며, China Union-Pay 모바일 결제와 관련하여 사용자의 점도에 미치는 영향을 연구하였다. 연구 분석결과에 따르면, 서비스 품질이 사용자가 인식 한 가치에 유의 한 영향을 미친다는 결과 나타났다. 서비스 품질은 사용자 점도에 유의 한 양의 관계를 갖다. 인식 된 값은 사용자 점도에 유의한 양의 효과를 나타났다. 사용자에 대한 브랜드 특성이 사용자 점도에 유의한 양의 효과를 나타났다. 브랜드 성격은 사용자가 인식 한 가치에 유의 한 양의 관계 영향을 미친다. 이 연구를 통해 모바일 결제 기업의 산업 발전에 대한 제안을 했고 모바일 결제발전에 대한 더 나은 의견을 제시 하였다. The purpose of this study is to explore the impact of Union-Pay mobile payments on user viscosity from the perspective of service quality and brand personality. In the future, it is meaningful for CUP to obtain a stable and loyal user group in China’s mobile payment market. This study uses SPSS22.0 and AMOS statistical analysis tools to conduct empirical research. In this case, this study uses mobile service quality and The brand personality is the independent variable, and the user’s viscosity is the dependent variable, which studies the impact on the user’s viscosity in the context of China Union-Pay mobile payment. the study. According to the analysis results, the research goal: service quality has a significant positive correlation effect on user perceived value; service quality has a significant positive correlation effect on user viscosity; perceived value has significant positive correlation effect on user viscosity; brand personality to user Viscosity has a significant positive correlation effect; brand personality has a significant positive correlation effect on user perceived value. Through this research, we can make Suggestions on the industrial development of mobile payment enterprises and provide better opinions on the development of mobile payment.

Robust State Observer Design for Dynamic Connection Relationships in Complex Dynamical Networks

Zi-lin Gao,Yin-He Wang,Jiang Xiong,Li-li Zhang,Wen-li Wang 제어·로봇·시스템학회 2019 International Journal of Control, Automation, and Vol.17 No.2

The complex dynamical network with the time-varying links may be regarded to be composed of the twomutually coupled subsystems, which are called the nodes subsystem and the connection relationships subsystemrespectively. Designing the state observer for the nodes subsystem has been discussed in some existing researches byemploying the known connection relationships. However, the state observer design for the connection relationshipssubsystem is not shown in the existing researches. In practical applications, the connection relationships subsystempossesses also the state variables such as the relationship strength in social network, the size of web tension in theweb winding system. Therefore, designing the state observer for the connection relationships subsystem is also ofpractical significance. In this paper, a novel state observer is proposed for the connection relationships subsystemmodeled mathematically by the Riccati matrix differential equation. The observer utilizes the output measurementsof the connection relationships subsystem and the state of nodes subsystem. Compared with the state observerof nodes subsystems which employs the known connection relationships, the state observer for the connectionrelationships subsystem employs the state of nodes subsystem and is represented in form of the matrix differentialequation. By using Lyapunov stability theory, it is proved in this paper that the state observer for the connectionrelationships subsystem is asymptotical under certain mathematic conditions. Finally, the illustrative simulation isgiven to show the efficiency and validity of the proposed method in this paper.

Flavonoid Glycosides and Potential Antivirus Activity of Isolated Compounds from the Leaves of Eucalyptus citriodora

Zhou, Zhong-Liu,Yin, Wen-Qing,Zou, Xiao-Peng,Huang, Dan-Ying,Zhou, Cui-Liu,Li, Lian-Mei,Chen, Ke-Cheng,Guo, Zi-Ying,Lin, San-Qing 한국응용생명화학회 2014 Applied Biological Chemistry (Appl Biol Chem) Vol.57 No.6

The extraction and solvent partition of the leaves of Eucalyptus citriodora, and repeated column chromatography for n-BuOH fraction yielded a new flavonoid glycoside, citrioside C (1), along with three known flavonoid glycosides (2-4). The latter were identified with kaempferol-3-O-${\beta}$-$\small{D}$-glucopyranosyl (12)-${\alpha}$-$\small{L}$-rhamnoside (2), kaempferol-3-O-${\alpha}$-$\small{L}$-rhamnoside (3), and quercetin-3-O-${\alpha}$-$\small{L}$-rhamnoside (4). Their chemical structures were identified on the basis of spectroscopic data analyses including NMR, MS, UV, and IR. All constitutents were isolated for the first time from the leaves of Eucalyptus citriodora. The potential antivirus activity of all the isolated compounds was evaluated. Compound 4 showed potent antiviral activity against respiratory syncytial virus with 50% inhibition concentration ($IC_{50}$) value of $1.9{\mu}g/mL$ and selective index value of 9.8.

Tracking Control for the Connection Relationships of Discrete-time Complex Dynamical Network Associated with the Controlled Nodes

Li-zhi Liu,Yin-He Wang,Zi-lin Gao 제어·로봇·시스템학회 2019 International Journal of Control, Automation, and Vol.17 No.9

In this paper, a general discrete-time complex dynamical network is regarded to be composed of the nodes subsystem and the links subsystem which are mutually coupled. Different from the existing researches on the stabilization and synchronization of nodes group, this paper mainly focuses on the dynamical behavior of connection relationships between the nodes, and the network nodes only play a helping and secondary role in the dynamics of connection relationships. Due to the state of the links subsystem is difficult to be measured accurately in practice appliances, the Riccati difference equation without any control input is employed as the dynamic model of the links subsystem, in which the dynamic coupling term is the first order polynomial about the state of nodes. With the helping of controlled nodes, the tracking problem is discussed for the links subsystem. By using thecoupling algebraic relation between the reference tracking targets of the nodes subsystem and the given trackingtarget of the links subsystem, the tracking control scheme is proposed for the nodes subsystem to force the linkssubsystem converges asymptotically to the given target. Finally, the simulations are used to show the validity of themethod in this paper.

Flavonoid Glycosides and Potential Antivirus Activity of Isolated Compounds from the Leaves of Eucalyptus citriodora

Zhong-Liu Zhou,Wen-Qing Yin,Xiao-Peng Zou,Dan-Ying Huang,Cui-Liu Zhou,Lian-Mei Li,Ke-Cheng Chen,Zi-Ying Guo,San-Qing Lin 한국응용생명화학회 2014 Applied Biological Chemistry (Appl Biol Chem) Vol.57 No.6

The extraction and solvent partition of the leaves ofEucalyptus citriodora, and repeated column chromatography for n-BuOH fraction yielded a new flavonoid glycoside, citrioside C (1),along with three known flavonoid glycosides (2-4). The latter wereidentified with kaempferol-3-O-β-D-glucopyranosyl (12)-α-L-rhamnoside(2), kaempferol-3-O-α-L-rhamnoside (3), and quercetin-3-O-α-Lrhamnoside(4). Their chemical structures were identified on thebasis of spectroscopic data analyses including NMR, MS, UV, andIR. All constitutents were isolated for the first time from the leavesof Eucalyptus citriodora. The potential antivirus activity of all theisolated compounds was evaluated. Compound 4 showed potentantiviral activity against respiratory syncytial virus with 50%inhibition concentration (IC50) value of 1.9 μg/mL and selectiveindex value of 9.8.

Molecular Characterization of Taenia multiceps Isolates from Gansu Province, China by Sequencing of Mitochondrial Cytochrome C Oxidase Subunit 1

Wen Hui Li,Wan Zhong Jia,Zi Gang Qu,Zhi Zhou Xie,Jian Xun Luo,Hong Yin,Xiao Lin Sun,Radu Blaga,Bao Quan Fu 대한기생충학열대의학회 2013 The Korean Journal of Parasitology Vol.51 No.2

중국조선족 뇌졸중환자의 인지기능의 다면적 분석비교

류명인,림은자,소희영,Liu, Ming Ren,Lin, Yin Zi,So, Hee-Young 한국재활간호학회 2006 재활간호학회지 Vol.9 No.1

Purpose: This study was to explore the cognitive function of Korean-Chinese stroke patient in China. Method: The study sample was 100 who were possible to communicate and agreed. The data were collected from one Brain's hospital at Yanji in China and by trained nurse from December 12, 2005 to April 28, 2006. The measurement tools were Digit span, Trail making, and MMSE-K. The data were analysed by SPSS Win 11.5 using frequency, t-test, ANOVA, and Pearson's correlation coefficients. Results: The mean score of DSF was 5.07, 3.42 of DSB, 161.37 of TMA, 229.28 of TMB, 22.64 of MMSE-K. There was a significant difference in DSF (F=6.35, p=.001), DSB (F=6.10, p=.001), TMA (F=3.53, p=.018), TMB (F=3.26, p=.025), MMSE-K score (F=12.97, p=.000) according to age, and DSF (F=6.67, p=.000), DSB (F=6.01, p=.000), TMA (F=5.82, p=.001), TMB (F=6.23, p=.001), and MMSE-K score (F=13.02, p=.000) according to educational level, and DSF (F=5.35, p=.006), DSB (F=3.16, p=.047), TMA (F=3.30, p=.041), TMB (F=3.42, p=.037), and MMSE-K score (F=4.95, p=.009) according to duration of disease, and DSB (F=3.54, p=.018), and MMSE-K (F=6.05, p=.001) according to frequencies of hospitalization. There was high correlation between DSF and DSB (r=.581, p=.000), TMA and TMB (r=.936, p=.000), MMSE-K and DSF (r=.579, p=.000), MMSE-K and DSB (r=.591, p=.000), DSF and TMA (r=.727, p=.000), and DSF and TMB (r=.721, p=.000). Conclusion: The cognitive evaluation score of Korean-Chinese stroke patients in China was in normal limit. The age, educational level, duration of disease and income were significant demographic characteristic affecting cognitive function. Further study need to compare the cognitive function of Korean-Chinese stoke patients in China and stoke patients in Korea.

An Efficient Multi-PCA Based On-line Monitoring Scheme for Multi-Stages Imperial Smelting Process

Zhi-kun Hu,Zhi-wen Chen,Wei-Hua Gui,Chun-hua Yang,Lin-zi Yin,Xiao-qi Peng 제어·로봇·시스템학회 2013 International Journal of Control, Automation, and Vol.11 No.2

Imperial Smelting Process (ISP) is one of the main methods for Zinc and Lead smelting. In this paper, we firstly focus on its unique characteristics that ISP consists of many feeding cycles repeated in a similar way, and the normal process changes and multiple operating conditions would be frequently found in the process which would always lead to false alarms. To this end, we classify each feeding cycles of ISP into initial stage, transition stage, and steady stage, and use standard PCA, first order perturbation (FOP) based recursive dynamic PCA and multi-mode approach to deal with them respectively. The monitoring results using real data show that the proposed scheme can be able to eliminate false alarms and detect faults efficiently.