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- 저자 : Lily, (검색결과 596 건)
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Lily, Lily,Yadav, K.L.,Prasad, K. Techno-Press 2013 Advances in materials research Vol.2 No.1
Lead-free compound $(Na_{0.5}Bi_{0.5})(Zr_{0.75}Ti_{0.25})O_3$ was prepared using conventional ceramic technique at $1070^{\circ}C$/4h in air atmosphere. X-ray diffraction analysis showed the formation of single-phase orthorhombic structure. Permittivity data showed low temperature coefficient of capacitance ($T_{CC}{\approx}5%$) up to $100^{\circ}C$. Complex impedance studies indicated the presence of grain boundary effect, non-Debye type dielectric relaxation and evidences of a negative temperature coefficient of resistance. The ac conductivity data were used to evaluate the density of states at Fermi level and apparent activation energy of the compound.
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The Effect of HIF-1α siRNA on Growth and Chemosensitivity of Mia-paca Cell Line
Lily Yang,강원경 연세대학교의과대학 2008 Yonsei medical journal Vol.49 No.2
Purpose: Hypoxia-inducible factor-1α (HIF-1α) primarily mediates the hypoxic response. HIF-1α induction by various stimuli contributes to cell proliferation and survival. To investigate the effect of HIF-1α, we used small interfering RNA (siRNA), and expected that cell apoptosis and sensitivity to chemotherapeutic drug increase, when we blocked the HIF-1α gene. Thus we performed in vitro and in vivo experiment to clarify the effect of hypoxia-inducible factor-1α on tumor growth. Received June 27, 2007 Accepted October 9, 2007 This paper was presented at the 9th World Congress on Gastrointestinal Cancer (WCGC) at Barcelona, Spain. (Jun 27-30, 2007). The corresponding author wishes to acknowledge the financial support of the Catholic Medical Center Research Foundation made in the program year of 2007 and the Sanofi-aventis. Reprint address: requests to Dr. Won Kyung Kang, Department of Surgery, The Catholic University of Korea, 505 Banpo-4, Seocho, Seoul 137-701, Korea. Tel: 82-2-590-2731, Fax: 82-2-590-1406, E-mail: wonkkang@catholic.ac.krMaterials and Methods: We made control and HIF-1α siRNA using vector plasmid and then transfected Mia-paca cell lines with these RNAs. After selection with geneticin, two new cell lines were made, confirmed via immunoblotting. After treating with gemcitabine, each cell line was assayed to confirm the effect of HIF-1α siRNA using the cell proliferation assay and capase-3 assay. And then in vivo study was performed using female athymic nude mice. After subcutaneously injecting each new cell lines, intraperitoneal gemicitabine chemotherapy was performed for 3 weeks. During that period, we analyzed the difference of tumor growth rate. Results: The tumor growth of HIF-1α siRNA-transfected group was slower than that of the control group both in vitro and in vivo experiment. Conclusion: The suppression of HIF-1α results in decrease of cell proliferation and increase of chemosensitivity of pancreatic cancer cell line. Therefore, targeting the HIF-1α may be useful treatment modality for some pancreatic cancers. Purpose: Hypoxia-inducible factor-1α (HIF-1α) primarily mediates the hypoxic response. HIF-1α induction by various stimuli contributes to cell proliferation and survival. To investigate the effect of HIF-1α, we used small interfering RNA (siRNA), and expected that cell apoptosis and sensitivity to chemotherapeutic drug increase, when we blocked the HIF-1α gene. Thus we performed in vitro and in vivo experiment to clarify the effect of hypoxia-inducible factor-1α on tumor growth. Received June 27, 2007 Accepted October 9, 2007 This paper was presented at the 9th World Congress on Gastrointestinal Cancer (WCGC) at Barcelona, Spain. (Jun 27-30, 2007). The corresponding author wishes to acknowledge the financial support of the Catholic Medical Center Research Foundation made in the program year of 2007 and the Sanofi-aventis. Reprint address: requests to Dr. Won Kyung Kang, Department of Surgery, The Catholic University of Korea, 505 Banpo-4, Seocho, Seoul 137-701, Korea. Tel: 82-2-590-2731, Fax: 82-2-590-1406, E-mail: wonkkang@catholic.ac.krMaterials and Methods: We made control and HIF-1α siRNA using vector plasmid and then transfected Mia-paca cell lines with these RNAs. After selection with geneticin, two new cell lines were made, confirmed via immunoblotting. After treating with gemcitabine, each cell line was assayed to confirm the effect of HIF-1α siRNA using the cell proliferation assay and capase-3 assay. And then in vivo study was performed using female athymic nude mice. After subcutaneously injecting each new cell lines, intraperitoneal gemicitabine chemotherapy was performed for 3 weeks. During that period, we analyzed the difference of tumor growth rate. Results: The tumor growth of HIF-1α siRNA-transfected group was slower than that of the control group both in vitro and in vivo experiment. Conclusion: The suppression of HIF-1α results in decrease of cell proliferation and increase of chemosensitivity of pancreatic cancer cell line. Therefore, targeting the HIF-1α may be useful treatment modality for some pancreatic cancers.
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Prevalence and Risk Factors of Functional Gastrointestinal Disorders in Infants in Indonesia
Lily Arsanti Lestari,Adhyatma Noor Rizal,Wahyu Damayanti,Yulianti Wibowo,Chang Ming,Yvan Vandenplas 대한소아소화기영양학회 2023 Pediatric gastroenterology, hepatology & nutrition Vol.26 No.1
Purpose: Information regarding functional gastrointestinal disorders (FGIDs) in infants is currently lacking in Indonesia. This study aimed to describe the prevalence and risk factors of FGIDs in infants aged 6 weeks to 4 months in Indonesia. Methods: This cross-sectional study of 433 infants was conducted between September 2018 and February 2020. Information on FGIDs was collected using the Infant Gastrointestinal Symptom Questionnaire and the Feeding Practice and Gut Comfort Questionnaire. Adapted Rome IV criteria were used to define the FGIDs. Results: The prevalence of regurgitation was 26.3%; 16.8% of the infants presented cryingrelated symptoms and 5.5% exhibited constipation. The statistical analyses revealed that constipation was associated with sex (odds ratio [OR], 2.74; 95% confidence interval [CI], 1.07-7.71; p=0.043), employment of the father (OR, 0.3; 95% CI, 0.12-0.77; p=0.01), and education of the mother (OR, 1.92; 95% CI, 1.07-3.51; p=0.031). Length at birth (OR, 0.74; 95% CI, 0.55-0.99; p=0.042) was associated with constipation. Length at visit (OR, 0.83; 95% CI, 0.76-0.91; p<0.001) was associated with regurgitation, and the weight at visit (OR, 0.58; 95% CI, 0.35-0.96; p=0.038) was associated with crying and/or colic. A history of parental FGIDs was associated with crying-related symptoms (OR, 2.12; 95% CI, 1.23-3.68; p=0.007). Conclusion: Regurgitation, crying, and constipation are common FGIDs in infants. Some parental and infant characteristics may be predictors for FGIDs. Further investigations are needed to evaluate the clinical relevance of our findings. Understanding the determinants of FGIDs will benefit healthcare professionals and parents to improve infant’s quality of life and better manage these condition.
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Real-Data Comparison of Data Mining Methods in Prediction of Diabetes in Iran
Lily Tapak,Hossein Mahjub,Omid Hamidi,Jalal Poorolajal 대한의료정보학회 2013 Healthcare Informatics Research Vol.19 No.3
Objectives: Diabetes is one of the most common non-communicable diseases in developing countries. Early screening and diagnosis play an important role in effective prevention strategies. This study compared two traditional classification methods (logistic regression and Fisher linear discriminant analysis) and four machine-learning classifiers (neural networks, support vector machines, fuzzy c-mean, and random forests) to classify persons with and without diabetes. Methods: The data set used in this study included 6,500 subjects from the Iranian national non-communicable diseases risk factors surveillance obtained through a cross-sectional survey. The obtained sample was based on cluster sampling of the Iran population which was conducted in 2005–2009 to assess the prevalence of major non-communicable disease risk factors. Ten risk factors that are commonly associated with diabetes were selected to compare the performance of six classifiers in terms of sensitivity, specificity, total accuracy, and area under the receiver operating characteristic (ROC) curve criteria. Results: Support vector machines showed the highest total accuracy (0.986) as well as area under the ROC (0.979). Also, this method showed high specificity (1.000) and sensitivity (0.820). All other methods produced total accuracy of more than 85%, but for all methods, the sensitivity values were very low (less than 0.350). Conclusions: The results of this study indicate that, in terms of sensitivity, specificity, and overall classification accuracy, the support vector machine model ranks first among all the classifiers tested in the prediction of diabetes. Therefore, this approach is a promising classifier for predicting diabetes, and it should be further investigated for the prediction of other diseases.
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HHT method for system identification and damage detection: an experimental study
Lily L. Zhou,Gang Yan 국제구조공학회 2006 Smart Structures and Systems, An International Jou Vol.2 No.2
Recently, the Hilbert-Huang transform (HHT) has gained considerable attention as a novel technique of signal processing, which shows promise for the system identification and damage detection of structures. This study investigates the effectiveness and accuracy of the HHT method for the system identification and damage detection of structures through a series of experiments. A multi-degree-of-freedom (MDOF) structural model has been constructed with modular members, and the columns of the model can be replaced or removed to simulate damages at different locations with different severities. The measured response data of the structure due to an impulse loading is first decomposed into modal responses using the empirical mode decomposition (EMD) approach with a band-pass filter technique. Then, the Hilbert transform is subsequently applied to each modal response to obtain the instantaneous amplitude and phase angle time histories. A linear least-square fit procedure is used to identify the natural frequencies and damping ratios from the instantaneous amplitude and phase angle for each modal response. When the responses at all degrees of freedom are measured, the mode shape and the physical mass, damping and stiffness matrices of the structure can be determined. Based on a comparison of the stiffness of each story unit prior to and after the damage, the damage locations and severities can be identified. Experimental results demonstrate that the HHT method yields quite accurate results for engineering applications, providing a promising tool for structural health monitoring.
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Lily Nari Kim,Eun-Geun Kim,김준회,Sung-Eun Choi,박욱,권성훈 대한화학회 2012 Bulletin of the Korean Chemical Society Vol.33 No.11
We have developed magnetically controllable gold nanoparticles by synthesizing superparamagnetic Fe3O4 core/gold shell nanoparticles. The core/shell particles have the capability of forming gold 1D chains in the presence of an external magnetic field. Here we demonstrate dynamic and reversible self-assembly of the gold 1D chain structures in an aqueous solution without any templates or physical or chemical attachment. The spatial configuration of gold chains can be arbitrarily manipulated by controlling the direction of a magnetic field. This technique can provide arbitrary manipulation of gold 1D chains for fabrication purpose. To demonstrate this capability, we present a technique for immobilization of the gold particle chains on a glass substrate.
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USING VIDEO MODELING TO SUPPORT COMMUNICATION INTENTS FOR AN ADOLESCENT WITH AUTISM
( Lily Yip ) 대구대학교 한국특수교육문제연구소 2015 Asia-Pacific Journal of Intellectual Disabilities Vol.2 No.1
Individuals with autism tend to be devalued because of the Triad of Impairment in which impairment of social communication is one. A lack of understanding regarding the subtle aspects of social communication and interaction can make it difficult for individuals with autism to make friends or get and keep a job. This three-month case study design aims to explore how video modeling can improve communication intents. The subject is a 19- year-old female with autism and mild intellectual disability. The subject uses non-conventional ways to communicate requests and protests. The communication needs and abilities matrix is used to establish the profile of the subject. The social interaction and communication pattern of the subject is analyzed through classroom observation, video record and interviewing of the parents and teachers. Using video modeling, the subject demonstrated the ability to communicate intents of request and protest successfully across two functional settings. Given the preference of individuals with autism for visual stimuli and avoidance of face-to-face attention, video-based instruction is promising in increasing social and adaptive skills. It is hope of this study to inspire and generate interest in teachers and parents to use video modeling to instruct lifelong planning for quality living and societal integration for individuals with autism. Using video modelling to support communication intents for an adolescent with autism
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