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Anti-HIV-1 Activity of Lignans from the Fruits of Schisandra rubriflora
Wei-Lie Xiao,Rui-Rui Wang,Wei Zhao,Ren-Rong Tian,Shan-Zhai Shang,Liu-Meng Yang,Jian-Hong Yang,Jian-Xin Pu,Yong-Tang Zheng,Han-Dong Sun 대한약학회 2010 Archives of Pharmacal Research Vol.33 No.5
This study investigated the 70% aqueous acetone extract of the fruits of Schisandra rubriflora which led to the isolation of eight lignans, including a new isolate, rubrisandrin C (1), and seven known lignans (2-8) . The structure of 1 was established by extensive 1D and 2D NMR spectroscopy and its absolute stereochemistry was determined by CD spectrum. Compounds 1-5 and 7-8 were evaluated for their anti-HIV-1 activity that showed inhibitory activity on HIV-1IIIB induced syncytium formation with EC50 values in the range of 2.26~20.4 μg/mL. Compounds 1 and 7 exerted their obvious protection of HIV-1IIIB inducted MT-4 host cells lytic effects with a selectivity index of 15.4 and 24.6, respectively.
A Review of Virtual Anchor Node Technology: Construction and Application
Zhang Hong-lie,Li Cheng,Zhao Xin,Liu Yan-ju 보안공학연구지원센터 2015 International Journal of Multimedia and Ubiquitous Vol.10 No.4
The localization accuracy of the wireless sensor network node is improved by introducing the virtual anchor node, so the virtual anchor node is constructed and applied by many researchers to optimize the localization algorithm further. This paper presents the broad definition of the virtual anchor node and indicates its significance in the wireless sensor network node localization; the wireless sensor network node localization algorithm based on the virtual anchor node is introduced mainly in two aspects of constructing the virtual anchor node and its application in localization. The scheme for constructing the virtual anchor node includes the random construction method, the geometric constraint method, the node upgrade method, the network training method, etc. And the scheme for its application in localization includes the model reconstruction method, the rank sequence method, etc. By making a concrete analysis of the localization scheme based on the virtual anchor node, its future research prospect and its application development trend are put forward.
Fu You Fu,Lie Zhao Liu,You Rong Chai,Li Chen,Tao Yang,Ai Fen Ma,Cun Ming Qu,Lin Jiang,Zheng Sheng Zhang,Jia Na Li 한국유전학회 2007 Genes & Genomics Vol.29 No.3
Husk proportion (HP) and lignin content (LC) are two important traits of seed quality of B. napus. Efficient selection of these two traits is an important way to improve the seed quality in meal improvement. A set of recombinant inbred lines (RILs) of B. napus (GH06 × Zhongyou 821) was used for mapping QTLs of HP and LC in a two-year study in different environments. 509 markers (78 SSR markers, 66 RAPD markers and 365 SRAP markers) were mapped on 26 linkage groups with an average length of 73.96 cM. The map covered a total of 1923 cM, and the average distance between two adjacent markers was 3.78 cM. Analysis of variance of LC and HP indicated that. LC might not be significantly affected by environment (F = 2.96 < 3.02) and HP might be affected by genotype × environment interactions. A total of 15 significant QTLs were detected in eight linkage groups with a LOD threshold value of 2.5 (LR ≥ 11.5) by CIM, explaining 4.99-16.14% of phenotype variation. Some QTLs of LC and HP were detected in near regions of the same linkage groups, such as qLCBB05-6-1 and qLCWZ06-6-1, qLCBB05-10-2 and qLCBB06-10-1 and qLCWZ06-10-2, qHPBB05-9-3 and qHPBB06-9-1, qHPBB05-10-4 and qHPBB06-10-2 and qHPBB06-10-3 and qHPWZ06-10-1. This study indicates that the repeatedly detected QTLs of LC and HP might be major-effect QTLs of LC and HP.
Preliminary Study of the Effect of Secondary Airflow on Fiber Attenuation During Melt Blowing
Huawei Xu,Zhijun Zhou,Jie Liu,Lie Zhao,Sheng Xie,Junfeng Zhang 한국섬유공학회 2022 Fibers and polymers Vol.23 No.11
In order to enhance the fiber attenuation during the melt-blown process, a pair of air nozzle, which could eruptairflow as secondary airflow, below the spinning die was arranged and used. Firstly, the effect of applying secondary airflowon the whole airflow was explored by Computational Fluid Dynamics (CFD) simulation. The simulation results demonstratethe interactive relationship between the primary airflow from the spinning die and the secondary airflow. Then, the airvelocity of the whole airflow at conditions of with and without secondary airflow was experimental verified. Finally, theeffect of secondary airflow on the fiber diameter and the fiber evenness was investigated by a spinning experiment. Thespinning results reveals that the application of secondary airflow does not certainly enhance the fiber attenuation. The fiberdiameter decreases only when the inlet velocity of secondary airflow is higher than a critical value. In addition, the spinningexperiment indicates that the application of secondary airflow improves the evenness of fiber.
Mapping of QTLs controlling content of fatty acid composition in rapeseed (Brassica napus)
Xing Ying Yan,Jia Na Li,Rui Wang,Meng Yan Jin,Li Chen,Wei Qian,Xin Na Wang,Lie Zhao Liu 한국유전학회 2011 Genes & Genomics Vol.33 No.4
The improvement of fatty acid composition is one of the major goals of breeding in rapeseed (Brassica napus). The aim of this study was to provide more information on the genetic determination of fatty acid composition by investigating quantitative trait loci (QTLs). The study was based on two-year of field trials (in 2006 and 2007) with a population of recombinant inbred lines (RILs), which originated from a cross between GH06 and P174. The level of erucic acid (C22:1) was significantly negatively correlated with those of palmitic acid (C16:0), oleic acid (C18:1), linoleic acid (C18:2), linolenic acid (C18:3), and eicosenoic acid (C20:1) in both years. A total of 40 QTLs for six fatty acids were detected and most of them were clustered on linkage groups N8, N9, and N13. These results suggested strongly that there were significant correlations between the levels of fatty acid components and would be useful for the future improvement of breeding programs focused on fatty acids in rapeseed.