現代建築空間에 表現된 場所性에 관한 硏究

우수령,李根宅,朴斗涌 嶺南大學校 環境問題硏究所 1991 環境硏究 Vol.10 No.2

The logic of Modern Architecture in the early part of the 20th century was begun to be criticized intensely, and functionalism, idealism, philosophy of university brought about the loss of identity. The attempt to retrieve the humanity by a methodology for solutions of given problems leads contemporary architecture to the pluralism. Consequently, contemporary architecture is to harmonize architecture with environment, and that is possible when we introduce the concept of place into architecture. The concept of place is not new, but rediscovery. Place is every-where human exists. For a long time a place has been understood in Genius Loci and a guardian deity. It is parted into natural and man-made place, and they are subdivided into romantic, classical, cosmic, complex landscape/architecture. Place is not abstract or geometrical but concrete. By definition, combination and concentration of space and control of the direction, place is where man orients, shelters and feels enclosure, intimacy, security and position. A method to express a sense of place based on a mental image of human who experiences a place is embodied through visualization, complementation and symbolization and when a sense of place is expressed. It is possible that man orients and is individualized.

In to the Digital Age : A Complement or Displacement?

Lee, Too-Young 한국문헌정보학회 1996 한국문헌정보학회지 Vol.30 No.4

Library and Information Policy in Korea and Current Issues

이두영,Lee, Too-Young 한국도서관협회 1999 圖協會報 Vol.40 No.3

이 발표문은 일본의 학술정보센터 (NACSIS, National Center for science Information Systems)가 수행하는 ‘국제공동연구’ 프로젝트에 참여한 우리 협회 이두영 회장이 지난 3월 5일 NACSIS(일본.동경)에서 열린 보고회에서 참석하여 발표한 것임.

Morphine Postconditioning Attenuates ICAM-1 Expression on Endothelial Cells

Min, Too Jae,Kim, Joong-il,Kim, Jae-Hwan,Noh, Kyung Hee,Kim, Tae Woo,Kim, Woon-Young,Lee, Yoon-Sook,Park, Young Cheol The Korean Academy of Medical Sciences 2011 JOURNAL OF KOREAN MEDICAL SCIENCE Vol.26 No.2

<P>The purpose of this study is to determine 1) whether morphine postconditiong (MPostC) can attenuate the intercellular adhesion molecules-1 (ICAM-1) expression after reoxygenation injury and 2) the subtype(s) of the opioid receptors (ORs) that are involved with MPostC. Human umbilical vein endothelial cells (HUVECs) were subjected to 6 hr anoxia followed by 12 hr reoxygenation. Three morphine concentrations (0.3, 3, 30 µM) were used to evaluate the protective effect of MPostC. We also investigated blockading the OR subtypes' effects on MPostC by using three antagonists (a µ-OR antagonist naloxone, a κ-OR antagonist nor-binaltorphimine, and a δ-OR antagonist naltrindole) and the inhibitor of protein kinase C (PKC) chelerythrine. As results, the ICAM-1 expression was significantly reduced in the MPostC (3, 30 µM) groups compared to the control group at 1, 6, 9, and 12 hours reoxygenation time. As a consequence, neutrophil adhesion was also decreased after MPostC. These effects were abolished by coadministering chelerythrine, nor-binaltorphimine or naltrindole, but not with naloxone. In conclusion, it is assumed that MPostC could attenuate the expression of ICAM-1 on endothelial cells during reoxygenation via the κ and δ-OR (opioid receptor)-specific pathway, and this also involves a PKC-dependent pathway.</P>

Morphine Attenuates Endothelial Cell Adhesion Molecules Induced by the Supernatant of LPS-Stimulated Colon Cancer Cells

Min, Too Jae,Park, Sang-Hee,Ji, Yi-Hwa,Lee, Yoon-Sook,Kim, Tae Woo,Kim, Jae Hwan,Kim, Woon-Young,Park, Young-Cheol The Korean Academy of Medical Sciences 2011 JOURNAL OF KOREAN MEDICAL SCIENCE Vol.26 No.6

<P>A large reservoir of bacterial lipopolysaccharide (LPS) is available in the colon and this could promote colon cancer metastasis by enhancing tumor cell adhesion, intravasation, and extravasation. Furthermore, adhesion molecules like ICAM-1, VCAM-1, and E-selectin play important roles in the adhesion of tumor cells to endothelium. This study was designed to determine whether morphine can attenuate the expressions of adhesion molecules up-regulated by the supernatant of LPS-stimulated HCT 116 colon cancer cells (LPS-Sup). In this study, we divided to three groups by cell-growth medium of human umbilical vascular endothelial cells (HUVECs): the control group was incubated in growth factor-free endothelial medium, the Sup group was incubated in the supernatant of HCT 116 cells (Sup), and the LPS-Sup group was incubated in LPS-Sup. To observe effect of morphine to the adhesion molecules expressions in the LPS-Sup group, we co-treated morphine with LPS or added it to LPS-Sup. Adhesion molecule expressions on HUVECs in all three groups were measured during incubation period. Consquentially, ICAM-1, VCAM-1, and E-selectin expressions on HUVECs were significantly lower when morphine was co-treated with LPS than not co-treated. Thus, we suggest that morphine affects the expressions of adhesion molecules primarily by attenuating LPS stimuli on tumor cells.</P>

전자자원 라이선스 관련 메타데이터 설정에 관한 연구

이두영,강순희,Lee, Too-Young,Kang, Soon-Hee 한국과학기술정보연구원 과학기술정보센터 2004 Journal of Information Science Theory and Practice Vol.35 No.4

오늘날 대부분의 도서관 전자자원 이용은 라이선스 계약에 의해 이루어지고 있다. 이용자의 전자자원 접속 및 이용은 라이선스 조건 범위 내에서 허용된다. 따라서 전자자원을 효율적으로 관리하고 적절한 서비스를 제공하기 위해서는 라이선스 관련 데이터요소를 체계적으로 관리할 필요가 있다. 이에 본 연구는 전자자원 관리를 위한 라이선스 관련 메타데이터를 설정하는데 그 목적이 있다. 본 연구방법으로 전자자원 메타데이터 스키마, 저작권 권리표현언어의 분석과 외국 대학도서관 전자자원 관리시스템의 라이선스 관련 데이터요소의 비교분석을 하였다. 이를 종합하여 최종적으로 전자자원 라이선스 관련 핵심요소와 선택요소로 구분하여 라이선스 관련 메타데이터를 설정하였다. Lately, most of the libraries subscribe electronic resources such as e-journals, under the license contracts for the access and use of these electronic resources. It was found that the management of licensed electronic resources in the library has become one of the major problems due to the lack of proper metadata elements in the existing management system of electronic resources. The purpose of the study is to establish metadata for licensed electronic resources.

조직문화가 지식공유에 미치는 영향에 관한 연구

이두영,남궁민,Lee, Too-Young,NamGoong, Min 한국과학기술정보연구원 과학기술정보센터 2002 Journal of Information Science Theory and Practice Vol.33 No.4

지식기반 사회에서 지식이 조직의 자산으로 인식되면서 지식의 효율적 관리 및 활용 필요성과 함께 지식경영이 주목을 끌게 되었다. 지식경영을 위해서는 조직구성원들이 업무를 수행하면서 얻은 노하우나 경험과 같은 지식을 조직 차원에서 공유하는 것이 중요하다. 그러나 자신의 지식은 자신만이 가지고 있기를 원하고, 다른 사람의 지식은 알아내서 갖고 싶어하는 것이 일반적인 사람의 성향이다. 그래서 조직 안에서 조직 구성원들 각자의 지식을 서로 공개하고 공유하려는 노력은 극히 부진한 것으로 나타났다. 본 연구는 조직 내에서 지식공유의 필요성에 대한 인식의 결여와 이를 위한 프로그램이나 공동의 노력이 극히 부진한 원인과 지식공유가 성공적으로 이루어질 수 있는 방안을 조직문화의 변화로부터 찾고자 하였다. In knowledge-based society, it is understood that the knowledge is an essential resources for effective management of the organization. Lately, knowledge management has been accepted by many organization as a new theory of management. But the problem is that people, a component of the organization tend not to open their own knowledge to others, but to keep seeking knowledge of others. It can be found in many research papers that there have been very little efforts for sharing knowledge among members of organization. The purpose of the study is to investigate the reasons for not sharing knowledge or ideas with others, to identify some cultural factors effecting their closed-minded attitude towards the sharing knowledge, and to find the solutions from the organizational culture.

치열의 임상분석

이광렬,이철호,유정준,박세영,임석원,김현식,이종균 대한대장항문학회 1996 Annals of Coloproctolgy Vol.12 No.4

학술 커뮤니케이션의 새로운 동향 : 자유이용을 중심으로

이두영,황옥경,Lee, Too-Young,Hwang, Ok-Gyung 한국과학기술정보연구원 과학기술정보센터 2003 Journal of Information Science Theory and Practice Vol.34 No.2

라이센싱을 통한 전자 저널의 이용은 학술 정보의 제한적인 이용 및 보존 문제를 부각시켜 왔고 이에 대한 해결방안으로 현재 다양한 학술 커뮤니케이션 유형들이 시도되고 있다. 자유이용은 이러한 대안적인 학술 커뮤니케이션 유형 중의 하나로서 새롭게 제시된 모델이다. 본 논문에서는 자유이용의 등장 배경 및 발전의 역사를 짚어보고 자유이용의 확산을 위해 선결되어야 할 문제점들을 고찰한 뒤 자유이용의 발전을 위해 도서관에 기대되어지는 역할을 제시하였다. The serials pricing and licensing crises have caused the problem of limited access to scholarly information and the problem of its preservation. To cope with these crises, various types of scholarly communication models are under study now. Open Access is one of the possible solutions among these new trials. This study has investigated the history of Open Access, articulated the first considerations for the spread of Open Access, and proposed the role of librarians during the progress.

학술정보 관리 및 유통시스템 구축 방안에 관한 연구

이두영,남태우,조인숙,Lee Too-Young,Nam Tae-Woo,Cho In-Sook 한국문헌정보학회 1997 한국문헌정보학회지 Vol.31 No.4

This study surveys science information resources and science information resource services institutions existing in the field of scientific research to analyse their strengths and weaknesses, which provide theoretical foundation of planning an effective and efficient nation-wide science information transfer system for Korea. This study also suggests right directions of developing a centralised system of science information for Korea. 본 연구는 우리나라 학술정보의 효율적인 관리 및 원활한 유통체제를 확립하기 위한 방안으로 우리나라 학술분야의 정보력실태조사를 통하여 국내외 학술정보서비스 및 유통현황조사 및 문제점을 분석하였다. 또한 국가적 학술정보 유통시스템 확립을 위한 기본 연구방향과 카테고리를 설정하고 종합방안을 제시하였다.