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박장규,성열훈,성범진,김영호,이증훈 충남대학교 의과대학 지역사회의학연구소 1990 충남의대잡지 Vol.17 No.2
The authors evaluated response to PUVA therapy in 44 vitiligo petients who did'nt show the spontaneous re-pigmentation. In the responded group to PUVA therapy after systemic administration of 8-methoxy psoralen, average MPD of female patients was 3.4 times higher than males, interestingly. Number of irradiation of UVA was similar between male and female, but total doses of female patients group were about 2 times than males till the first re-pigmented spots were noted. The response to PUVA therapy was quite different according to duration of disease and site of lesion. Therefore, we suppose that it is necessary to consider sex of patient, duration of disease, location of vitiligo before making a plan of PUVA therapy.
Lee, Ju-Suk,Kim, Ye-Jin,Ryu, Ki-Hyun,Han, Tae-Ho,Park, Kuen-Woo,Chung, Kyu-Hwan,Lee, Chan,Lee, Gung-Pyo,Kim, Sun-Hyung,Hong, Jin-Sung,Park, Young-Doo,Woo, Eun-Taeck,Park, Sung-Chul,Son, Dae-Yeul 한국원예학회 2012 Horticulture, Environment, and Biotechnology Vol.53 No.2
Pollen of genetically modified (GM) pepper containing the gene for cucumber mosaic virus (CMV) coat protein (CP) and GM Chinese cabbage with high phenylethylisothiocyanate (PEITC) content was investigated for assessment of allergic risk. Amino acid (AA) sequences of the inserted gene products of GM virus resistant pepper and GM Chinese cabbage with high PEITC content were compared with those of known allergens. No known allergen greater than 35% AA sequence homology, over 80 AA window or more than 8 consecutive identical AA was found. Protein patterns of GM/non-GM pepper and Chinese cabbage pollen extracts in SDS-PAGE analysis showed the same distribution of protein bands among the GM and non-GM pepper or Chinese cabbage, respectively. Sera from pollen allergic patients showed some IgE reactivity via immunoblotting and ELISA; however, no differences were observed between the pollen of GM and non-GM pepper or Chinese cabbage, respectively. Based on these results, we conclude that pollens of the virus resistant GM pepper and GM Chinese cabbage with high PEITC have no differences in their protein composition or allergenicity relative to non-GM pepper and Chinese cabbage.
Implementation of Cardiovascular Disease (CVD) Level Prediction Processor using Aptamer Biochip
Kyu-Yeul Wang,Sang-Seol Lee,Joo-Kyung Kim,Oh Hyuk Kwon,Ji-Yoon Kim,Byoung-Tak Zhang,Chong Ho Lee,Jeahyun Park,Duck-Jin Chung 대한전자공학회 2007 ITC-CSCC :International Technical Conference on Ci Vol.2007 No.7
In the developed country, cardiovascular disease (CVD) has considerably affected in a notice of death. In recent study, 40% of the disease mortality is related with CVD in the case of United States. Because of dangerousness of CVD, there is the growth of need that the method predicts whether some patient has CVD. To meet those need, there are so many efforts include our study. In our study, we propose the efficient diagnosis system to cover public people with cheap medical fee. The processor use aptamer biochip which is manufactured by Geno Prot Inc. to generate test pattern. This aptamer biochip is used for detection of specific protein included in patient’s serum. We can get abbreviated test set by using hypernetwork model. And then the processor generates CVD prediction results with the reduced data and only spends minimal processing time. The proposed CVD processor is verificated through Xilinx FPGA. The results show that the processor is well qualified as CVD diagonosis processor.
Undergraduate courses for enhancing design ability in naval architecture
Lee, Kyu-Yeul,Ku, Namkug,Cha, Ju-Hwan The Society of Naval Architects of Korea 2013 International Journal of Naval Architecture and Oc Vol.5 No.3
Contemporary lectures in undergraduate engineering courses typically focus on teaching major technical knowledge-based theories in a limited time. Therefore, most lectures do not allow the students to gain understanding of how the theories are applied, especially in Naval Architecture and Ocean Engineering departments. Shipyards require students to acquire practical ship design skills in undergraduate courses. To meet this requirement, two lectures are organized by the authors; namely, "Planning Procedure of Naval Architecture & Ocean Engineering" (PNAOE) and "Innovative Ship Design" (ISD). The concept of project-based and collaborative learning is applied in these two lectures. In the PNAOE lecture, sophomores receive instruction in the designing and building of model ships, and the students' work is evaluated in a model ship contest. This curriculum enables students to understand the concepts of ship design and production. In the ISD lecture, seniors learn how to develop their creative ideas about ship design and communicate with members of group. They are encouraged to cooperate with others and understand the ship design process. In the capstone design course, students receive guidance to facilitate understanding of how the knowledge from their sophomore or junior classes, such as fluid mechanics, statics, and dynamics, can be applied to practical ship design. Students are also encouraged to compete in the ship design contest organized by the Society of Naval Architects of Korea. Moreover, the effectiveness of project-based and collaborative learning for enhancing interest in the shipbuilding Industry and understanding the ship design process is demonstrated by citing the PNAOE and ISD lectures as examples.
Economic Optimization Study for a $125,000m^3$ Class LNG Carrier
Lee, Kyu-Yeul,Lee, Dong-Kon,Jung, Ho-Hyun,Lee, Chul-Hee The Society of Naval Architects of Korea 1984 大韓造船學會誌 Vol.21 No.4
This study is concerned with the economic aspects of $125,000m^3$ class LNG carriers with different propulsion plant such as conventional steam turbine and slow speed diesel engine with reliquefaction plant. The ship's speed and L/B ratio were optimized with criterion of required freight rate(RFR) by using the PROCAL computer program package. In order to investigate the effect of fuel oil price, round trip distance and boil-off rate on the RFR and the optimum speed, sensitivity analysis were also performed.
Lee Sang Hun,Lee Kyu-Yeul,Woo Yoonwhan,Lee Kang-Soo The Korean Society of Mechanical Engineers 2005 JOURNAL OF MECHANICAL SCIENCE AND TECHNOLOGY Vol.19 No.2
We propose a feature-based multi-resolution representation of B-rep solid models using history-based Boolean operations based on the merge-and-select algorithm. Because union and subtraction are commutative in the history-based Boolean operations, the integrity of the models at various levels of detail (LOD) is guaranteed for the reordered features regardless of whether the features are subtractive or additive. The multi-resolution solid representation proposed in this paper includes a non-manifold topological merged-set model of all feature primitives as well as a feature-modeling tree reordered consistently with a given LOD criterion. As a result, a B-rep solid model for a given LOD can be provided quickly, because the boundary of the model is evaluated without any geometric calculation and extracted from the merged set by selecting the entities contributing to the LOD model shape.
A User-Oriented Interactive Model for the Conceptual Design of Bulk Cargo Ships
Lee, Dong-Kon,Lee, Kyung-Ho,Han, Soon-Hung,Lee, Soon-Sub,Lee, Kyu-Yeul,Shin, Soo-Chol,Shin, Dong-Won,Lee, Jong-Chol,Kwon, Sung-Chil The Society of Naval Architects of Korea 1994 Selected papers of the society of naval architects Vol.2 No.1
This paper describes a design model for the conceptual design of ships. Existing design models have problems such that their operating mode of batch versions cannot reflect the design procedures in reality. Reliability of the results is low because the performance estimations are based mainly on empirical formulas. To improve the problems of existing design models, a new design model has been developed. The new model consists of an interactive user interface, a database of main engines, a database of particulars of existing ships, and ten modules for performance estimations. To develop such a user-oriented system, the concept of graphical user interface (GUI) is adopted.
Undergraduate courses for enhancing design ability in naval architecture
Kyu-Yeul Lee,Namkug Ku,Ju-Hwan Cha 대한조선학회 2013 International Journal of Naval Architecture and Oc Vol.5 No.3
Contemporary lectures in undergraduate engineering courses typically focus on teaching major technical knowledge-based theories in a limited time. Therefore, most lectures do not allow the students to gain understanding of how the theories are applied, especially in Naval Architecture and Ocean Engineering departments. Shipyards require students to acquire practical ship design skills in undergraduate courses. To meet this requirement, two lectures are organized by the authors; namely, “Planning Procedure of Naval Architecture & Ocean Engineering” (PNAOE) and “Innovative Ship Design” (ISD). The concept of project-based and collaborative learning is applied in these two lectures. In the PNAOE lecture, sophomores receive instruction in the designing and building of model ships, and the students’ work is evaluated in a model ship contest. This curriculum enables students to understand the concepts of ship design and production. In the ISD lecture, seniors learn how to develop their creative ideas about ship design and communicate with members of group. They are encouraged to cooperate with others and understand the ship design process. In the capstone design course, students receive guidance to facilitate understanding of how the knowledge from their sophomore or junior classes, such as fluid mechanics, statics, and dynamics, can be applied to practical ship design. Students are also encouraged to compete in the ship design contest organized by the Society of Naval Architects of Korea. Moreover, the effectiveness of project-based and collaborative learning for enhancing interest in the shipbuilding Industry and understanding the ship design process is demonstrated by citing the PNAOE and ISD lectures as examples.
Lee Sang Hun,Lee Kyu-Yeul,Woo Yoonwhan,Lee Kang-Soo The Korean Society of Mechanical Engineers 2005 JOURNAL OF MECHANICAL SCIENCE AND TECHNOLOGY Vol.19 No.2
The requirements of multi-resolution models of feature-based solids, which represent an object at many levels of feature detail, are increasing for engineering purposes, such as analysis, network-based collaborative design, virtual prototyping and manufacturing. To provide multi-resolution models for various applications, it is essential to generate adequate solid models at varying levels of detail (LOD) after feature rearrangement, based on the LOD criteria. However, the non-commutative property of the union and subtraction Boolean operations is a severe obstacle to arbitrary feature rearrangement. To solve this problem we propose history-based Boolean operations that satisfy the commutative law between union and subtraction operations by considering the history of the Boolean operations. Because these operations guarantee the same resulting shape as the original and reasonable shapes at the intermediate LODs for an arbitrary rearrangement of its features, various LOD criteria can be applied for multi-resolution modeling in different applications.