http://chineseinput.net/에서 pinyin(병음)방식으로 중국어를 변환할 수 있습니다.
변환된 중국어를 복사하여 사용하시면 됩니다.
Deoxy[Hb+Mb] increases consistently up to peak oxygen consumption in elite cyclists
( Philippe Gendron ),( Louis Laurencelle ),( Francois Trudeau ),( Claude Lajoie ) 한국스포츠정책과학원(구 한국스포츠개발원) 2018 International Journal of Applied Sports Sciences Vol.30 No.1
This study aimed to compare deoxygenation in the vastus lateralis in the skeletal muscle microvasculature of nine world-class/elite (WC/E) vs. thirty-one well-trained/trained (T) cyclists by near infrared spectroscopy (NIRS) during a maximal aerobic power (MAP) test. Interaction analysis showed that 1st degree polynomial trends across % peak oxygen consumption (%VO<sub>2</sub>peak) differed significantly between WC/E and T cyclists on deoxygenated hemoglobin-myoglobin (Δ[HHb]) and on total hemoglobin-myoglobin (Δ[THb]) from 70 to 100% of VO<sub>2</sub>peak. These results show that the linear slopes of these trends were different. Near-plateau of Δ[HHb] was observed in T cyclists, whereas a consistent increase up to VO<sub>2</sub>peak was seen in WC/E cyclists. The Δ[THb] curve declined in T cyclists suggesting that blood volume in the vastus lateralis microcirculation decreases from 70 to 100% of VO<sub>2</sub>peak whereas it increases slowly but continuously to 95% of VO<sub>2</sub>peak in WC/E cyclists. The results of this study showed that deoxygenation in the vastus lateralis increases consistently up to VO<sub>2</sub>peak in WC/E cyclists and seems to be influenced by blood volume in the microcirculation.
Diffusion and adoption of the Long-Term Athlete Development model among Canadian coaches
( François Trudeau ),( Louis Laurencelle ),( Charlotte Beaudoin ),( Claude Lajoie ) 한국스포츠정책과학원 2021 International Journal of Applied Sports Sciences Vol.33 No.2
The aim of the present study was to document the process of Long-term Athlete Development (LTAD) adoption by Canadian sport coaches, and to identify predictors of: 1) their attitude and intention to adopt such a social innovation, and 2) their LTAD adoption level. Using Rogers’ innovation diffusion theory, a survey of 499 Canadian coaches was conducted to identify the factors associated with three variables: coaches’ attitude towards LTAD, intention to adopt LTAD, and LTAD adoption status. 279 (56%)(35.4 ± 12.1 years) of them knew LTAD and filled out the entire questionnaire. Perceived knowledge of LTAD, its trialability, observability, intention to adopt, coaches’ certification level, and organisational support were the best predictors of LTAD model adoption level in coaching’ practice (R2=0.579, F9,184=28.32, p<0.001). Coaches in late-developing sports declared having greater knowledge of LTAD, more capacity for its implementation, and lower perceived complexity of application.
Precise Manipulation of Chromosomes in Vivo Enables Genome-Wide Codon Replacement
Isaacs, Farren J.,Carr, Peter A.,Wang, Harris H.,Lajoie, Marc J.,Sterling, Bram,Kraal, Laurens,Tolonen, Andrew C.,Gianoulis, Tara A.,Goodman, Daniel B.,Reppas, Nikos B.,Emig, Christopher J.,Bang, Duhe American Association for the Advancement of Scienc 2011 Science Vol.333 No.6040
<P>We present genome engineering technologies that are capable of fundamentally reengineering genomes from the nucleotide to the megabase scale. We used multiplex automated genome engineering (MAGE) to site-specifically replace all 314 TAG stop codons with synonymous TAA codons in parallel across 32 Escherichia coli strains. This approach allowed us to measure individual recombination frequencies, confirm viability for each modification, and identify associated phenotypes. We developed hierarchical conjugative assembly genome engineering (CAGE) to merge these sets of codon modifications into genomes with 80 precise changes, which demonstrate that these synonymous codon substitutions can be combined into higher-order strains without synthetic lethal effects. Our methods treat the chromosome as both an editable and an evolvable template, permitting the exploration of vast genetic landscapes.</P>
채종서,미트라게게르치,한인식,S. Y. Han,I. W. Jeong,주관식,김은주,김용균,E. Kistenev,권영일,J. G. Lajoie,Z. Li,J.H.Lee,K. S. Lim,J. M. Park,K. S. Park,H. S. Song,D. G. Sue,A. Sukhanov 한국물리학회 2014 THE JOURNAL OF THE KOREAN PHYSICAL SOCIETY Vol.65 No.1
The Si Mini-Pad sensor is an essential component of the MPC-EX preshower detector. Thisdetector will be integrated into the PHENIX experiment at Brookhaven National Laboratory’s RelativisticHeavy Ion Collider. We describe the development of the surface pattern and the fabricationprocess of the Si Mini-Pad sensor and present a test by the low energyirradiation that is sensitiveto the surface design.
( Philippe Gendron ),( Pascal Dufresne ),( Louis Laurencelle ),( Francois Trudeau ),( Simon Bergeron-vaillancourt ),( Anthony Bonal ),( Claude Lajoie ) 한국스포츠정책과학원(구 한국스포츠개발원) 2016 International Journal of Applied Sports Sciences Vol.28 No.1
The purpose was to examine improvements of performance and different physiological parameters in ten trained male cross-country mountain bikers after a supra-maximal interval training (SMIT) program of 8 sessions. Each session comprised 60 to 90 repeated 1-minute bouts consisting of a 20-s effort at 115% of maximal aerobic power (MAP), followed by 40-s recovery at 50% of MAP. Performance time to complete the virtual time-trial performance test was reduced significantly by -4.2%. Pulmonary sub-maximal oxygen consumption and deoxyhemoglobin in vastus lateralis decreased significantly by .4.7% and -21.9% respectively during the MAP test. Our findings suggest that SMIT program might improve performance and cycling efficiency in XC mountain bikers.
Effects of Damage Caused by Non-ionizing Energy Loss in Si Mini-Pad Sensors for the PHENIX MPC-EX
채종서,미트라게게르치,한인식,S. Y. Han,I. W. Jeong,주관식,김은주,S. G. Kim,김용균,E. Kistenev,권영일,J. G. Lajoie,Z. Li,J. H. Lee,K. S. Lim,S. H. Lim,J. M. Park,K. S. Park,S. Y. Park,H. S. Song,D. G. Sue,A. Sukhanov 한국물리학회 2014 THE JOURNAL OF THE KOREAN PHYSICAL SOCIETY Vol.65 No.11
The PHENIX MPC-EX is an W/Si pre-shower detector operating at small angles with respectto the beam in the Relativistic Heavy Ion Collider (RHIC). The Si Mini-Pad sensors are the activeelement of the detector. The expected hadron flux to the Si Mini-Pad sensors will generate significantnon-ionizing energy loss in the sensors, which may damage the crystalline structure of thesensor’s bulk material. We investigated the nature of the hadron flux to the Si Mini-Pad sensorsthrough a full simulation and determined its effect on the sensor’s characteristics based on a beamtest. The investigation showed key issues in designing a preshower detector using silicon sensorsand operating under a large neutron fluence and offered valuable information on the operation ofthe MPC-EX detector.