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미얀마의 말라리아, 결핵 및 간염의 표준 진단법 및 치료법 현황
한은택,이종석,정재훈,장철훈,미야트 투트 뉴느트,Wah Wah Aung,Yi Yi Kyaw,Kyaw Zin Thant 대한진단검사의학회 2017 Laboratory Medicine Online Vol.7 No.3
Malaria, tuberculosis, and hepatitis are common and notorious infectious diseases in Myanmar. Despite intensive efforts to control these diseases, their prevalence remains high. For malaria, which is a vector-borne disease, a remarkable success in the reduction of new cases has been achieved. However, the annual number of tuberculosis cases has increased over the last few decades, and the prevalence of chronic viral hepatitis infection has been high in Myanmar and other nearby countries. Early detection and prompt treatment are crucial to control these diseases. We have devoted our research efforts to understanding the status of these infectious diseases and working towards their eventual elimination for the last four years with the support of the Korea International Cooperation Agency. In the modern era, an infection that develops in one geographical area can spread globally because national borders do not effectively limit disease transmission. Our efforts to understand the status of infectious diseases in Myanmar will benefit not only Myanmar but also neighboring countries such as Korea. 말라리아, 결핵, 간염은 미얀마의 중요한 감염 질환으로, 퇴치를 위한 노력에도 불구하고 여전히 심각한 상황이다. 곤충 매개 질환의 하나인 말라리아는 관리 목표치에 도달하여 관리가 잘 이루어지고 있음을 보여주고 있다. 하지만 결핵은 과거 수십년간 오히려 증가하고 있으며, 만성 바이러스성 간염은 주변 국가들에 비해 여전히 높은 수준이다. 이들 감염 질환을 통제하는데 중요한 방법은 조기 진단과 치료이다. 저자들은 최근 4년간 KOICA의 지원으로 미얀마의 주요 감염병의 실태를 파악하고, 감염병 퇴치를 위한 노력을 기울여 왔다. 지금은 이동 수단의 발달로 인해 감염병의 전파에서 국경의 한계가 없어졌기에, 세계 어느 곳에서의 감염도 다른 지역의 사람들에게 끼치는 영향이 크다. 비록 우리나라에서 멀리 떨어진 곳이기는 하나, 미얀마의 감염병 퇴치 노력이 우리나라와 전 세계의 인류 보건 향상에 중요한 영향을 끼칠 것으로 생각한다.
Hlaing Myat Thu,Theingi Win Myat,Mo Mo Win,Kyaw Zin Thant,Shofiqur Rahman,Kouji Umeda,Sa Van Nguyen,Faustino C. Icatlo Jr,Kyoko Higo-moriguchi 한국축산식품학회 2017 한국축산식품학회지 Vol.37 No.1
The rotavirus-induced diarrhea of human and animal neonates is a major public health concern worldwide. Until recently, no effective therapy is available to specifically inactivate the rotavirion particles within the gut. Passive immunotherapy by oral administration of chicken egg yolk antibody (IgY) has emerged of late as a fresh alternative strategy to control infectious diseases of the alimentary tract and has been applied in the treatment of diarrhea due to rotavirus infection. The purpose of this concise review is to evaluate evidence on the properties and performance of anti-rotavirus immunoglobulin Y (IgY) for prevention and treatment of rotavirus diarrhea in human and animal neonates. A survey of relevant anti-rotavirus IgY basic studies and clinical trials among neonatal animals (since 1994-2015) and humans (since 1982-2015) have been reviewed and briefly summarized. Our analysis of a number of rotavirus investigations involving animal and human clinical trials revealed that anti-rotavirus IgY significantly reduced the severity of clinical manifestation of diarrhea among IgY-treated subjects relative to a corresponding control or placebo group. The accumulated information as a whole depicts oral IgY to be a safe and efficacious option for treatment of rotavirus diarrhea in neonates. There is however a clear need for more randomized, placebo controlled and double- blind trials with bigger sample size to further solidify and confirm claims of efficacy and safety in controlling diarrhea caused by rotavirus infection especially among human infants with health issues such as low birth weights or compromised immunity in whom it is most needed.
Molecular Evidence of Drug Resistance in Asymptomatic Malaria Infections, Myanmar, 2015
Nyunt, Myat Htut,Shein, Thinzar,Zaw, Ni Ni,Han, Soe Soe,Muh, Fauzi,Lee, Seong-Kyun,Han, Jin-Hee,Thant, Kyaw Zin,Han, Eun-Taek,Kyaw, Myat Phone Centers for Disease Control and Prevention 2017 Emerging infectious diseases Vol.23 No.3
<P>Artemisinin resistance containment in Myanmar was initiated in 2011 after artemisinin-resistant <I>Plasmodium falciparum</I> malaria was reported. Molecular evidence suggests that asymptomatic malaria infections harboring drug resistance genes are present among residents of the Myanmar artemisinin resistance containment zone. This evidence supports efforts to eliminate these hidden infections.</P>