복강경하 대장절제술을 시행 받는 환자에서 라모세트론과 온단세트론외 술 후 오심 및 구토 예방 효과 비교

김효중;어전영;어근무;어정한;엄세훈;조광래;김명훈 인제대학교 2011 仁濟醫學 Vol.32 No.-

Objectives : We evaluated the efficacy of ramosetron and ondansetron for preventing postoperative nausea and vomiting (PONV) in laparoscopic colectomy. Methods and Materials : Eighty patients who received laparoscopic colectomy were randomly divided into two groups: R group (ramosetron 0.1mg PO) and O group (ondansetron 4mg twice IV). Injection or oral medication was administered before the induction of anesthesia in each group. Injection was administered at the end of surgery in O group. General anesthesia was induced using propofol and rocuronium, and maintained with sevoflurane, remifentanil and air (FiO2 0.5), We investigated the incidences of PONV in each group by the Rhodes index of nausea, vomiting and retching (RINVR) at postoperative 6 and 24 hours. Results : The incidence of PONV was not different between group at each time points after surgery (at postoperative 6 hours: 20% in group R, 17.5% in group 0, at postoperative 24 hours; 12.5% in group R, 7.5% in group 0). There was no difference in the severity of PONV, satisfaction, rescue drug usage. Conclusion : Prophylactic therapy with ramosetron is as effective as conventional prophylactic therapy with ondansetron for preventing PONV in general anesthesia for laparoscopic colectomy.

당뇨병과 동반된 화농성 간농양의 임상상 및 예후인자

오은숙,강무일,이원영,오기원,임동준,이소영,이정민,고승현,김성래,안유배,손현식,윤건호,차봉연,이광우,손호영,강성구 대한당뇨병학회 2000 임상당뇨병 Vol.1 No.1

연구배경: 감염질환은 혈관질환과 함께 당뇨병의 중요한 사망원인의 하나이며, 혈당조절이 불량할수록 감염 빈도가 증가됨은 잘 알려져 있다. 간농양의 발생이 있어서도 당뇨병은 중요한 기저질환 중의 하나이다. 일반적으로 간농양의 가장 흔한 원인균은 Escherichi coli라고 알려져 있으나, 최근 당뇨병을 가진 간농양 환자에서 Klesiella pneumoniae의 검출이 증가되고 있다. 또 최근 연구에 의하면 K.pneumonie가 간농양의 가장 흔한 원인균이며, K. pneumoniae에 의한 간농양은 K.pneumoniae 이외의 균주에 의한 간농양보다 당뇨병과 밀접히 관련되어 있다고 보고된 바 있다. 이에 저자들은 간농양 환자를 대상으로 당뇨병환자의 빈도를 알아보고, 그 원인균 및 특징을 비당뇨병 환자들의 경우와 비교해 보고자 하였다. 방법: 1992년 1월부터 1999년 6월까지 방사선학적 검사 혹은 수술에 의해 간농양이 확인되거나, 경피적 천자나 수술을 통한 배농액 배양, 혹은 혈액 검사에서 원인균이 증명된 182명의 환자를 대상으로 후향적 임상고찰을 실시하였다. 결과: 화농성 농양을 가진 167명의 환자(남:94명, 여:73명)중 당뇨병을 가진 환자는 54명 (남:30명, 여:24명)으로 32.3%를 차지하였다. 환자의 평균나이는 당뇨군에서 62.1 ± 13.4세, 비당뇨군에서는 55.1 ±15.5세로 당뇨군에서 높았으며(p=0.0021), 남녀간의 평균나이 비교 시 두 군 모두 여성의 나이가 의미있게 높았다. 비당뇨군에 비하여 당뇨군의 경우 저알부민혈증의 빈도와 aspartate transaminase가 증가되어있었다. 원인균주는 K. pneumoniae (당뇨군54%, 비당뇨군 39.1%), E. coli(당뇨군 17.5%, 비당뇨군 18.8%), Pseudomonas aeruginosa, Streptococcus viridans, Enterococcus 순이었으며 두 군간의 의미는 차이는 없었으나 K. pneumoniae의 경우 다른 균종에 비해 단독감염의 빈도가 높았다(82.8%). 사망률은 당뇨군에서 16.7%, 비당뇨군에서 7.1%로 당뇨군에서 의미있게 높았으며(p=0.019), 당뇨군에서의 사망환자는 모두 패혈증이 동반되어 있었다. 당뇨환자의 사망군은 생존군에 비해 당뇨병 이환기간이 길고 혼합감염의 빈도가 높았다(p=0.046). 검사실 소견에서는 총 빌리루빈 및 알카리성 포스파타제의 증가가 관찰되어 있었다. 결론: E. coli가 간농양의 주된 원인균이라는 기존 보고와는 달리 당뇨군과 비당뇨군 모두 K. pneumoniae가 간농양의 주된 원인균이었다. 또한 당뇨 유병기간이 길고 당뇨조절이 불량한 환자에서 혼합감염이며 총 빌리루빈 및 알카리성 포스파타제의 증가등과 같은 위험인자가 존재할 경우 사망률이 증가될 수 있으므로 이들 군에서는 적극적인 치료가 필요할 것으로 사료된다. Background: Liver abscesses are commonly associated with underlying disease, particularly diabete mellitus. The number of the liver abscesses caused by Klebslella pneumoniae in diabetic patient has been increased in Korea nowadays. This study was conducted to clarify the clinical presentation and prognostic factors of pyogenic liver abscesses, especially in diabetic patients and to determine the proportion of K. pneunomiae as a pathogen in liver abscess in Korea. Methods: Medical records of 167 patients treated for pyogenic liver abscess from January, 1992 through June, 1999 were reviewed retrospectively in detail. Major Pathogenic organism, clinical manifestations, prognostic factors, the importance of diabetes mellilus as an underlying disease and its effect on clinical features and prognosis were analyzed. Results: Among 167 cases of pyogenic liver abscess, underlying diabetes mellitus was present in 32.3%. The mean age of patients was 62.7 13.4 years in diabetic liver abscess group and 55.1 15.5 years in non-diabetic liver abscess group. Most liver abscesses were cryptogenic in origin or secondary to the billary tree diseases. The clinical presentations among the two groups were not significantly different. When compared to patients without diabetes, patients with diabetes had significantly higher proportions of hypoalbuminemia and elevated aspartate transaminase level. The most common organism of the pyogenic abscess was K. pneumoniae in both groups. Percutaneous drainage of the abscess with appropriate antibiotics was the most commonly used therapeutic modality in liver abscess. The mortality rate of diabetic liver abscess is 16.1 % and 7.1% in nondiabetic liver abscess. Complications, especially septicemla, were found more frequently in patients with diabetes than in patients without diabetes (64.8% vs 28.3%, septicemia : 31.5% vs 9.7%). The factors influencing mortality in the diabetic liver abscess were disease duration, mixed infection, presence of septicemia, elevated bilirubin and alkaline phosphatase. Conclusions: In contrast to prior report that the E. coli was the most common pathogen in liver abscess, we found that K. pneumoniae was the most common organism cultured in liver abscess. Diabetic patients have more complications and higher mortality than patients without diabetes. Early detection and proper treatment are needed to improve the outcome for diabetic patient with liver abscess.

Rocuronium의 애별투여방법이 모지내전근의 이완에 미치는 영향

최영균,김승수,이원진,조광래,이상은,김영환,임세훈,이정한,이근무,정순호,김영재,신치만 인제대학교 2009 仁濟醫學 Vol.30 No.-

Objective : There are controversies in pnmmg technique of rocuronium whether it can or can't shorten the onset time. We want to compare the effects of two different priming doses and intervals of rocuronium. Materials and Methods : After giving propofol, 50 patients were randomly assigned to 5 groups. Group I received a placebo, followed 3 min later by rocuronium 0.6 mg/kg. Priming doses and intervals of Group II, Ill, N, V were 0.06 rng/kg and 2 min, 0.12 mg/kg and 2 min, 0.06 rug/kg and 3 min, 0.12 mg/kg and 3 min, respectively. Total dose of rocuronium was 0.6mg/kg. Train of four (TOF) count or ratio and 1st twitch height of TOF (T1) were monitored with 15 secondsintervals. TOF ratio of each groups just before bolus injection, duration for TOF count to reach zero and duration for Tl to reach 95% depression after bolus injection were compared. Results : Duration for TOF count to reach zero and duration for Tl to reach 95% depression after bolus injection were decreased in priming groups compared to Group 1 (P < 0.01) In group V, significant depression of TOF ratio just before bolus injection was seen (P < 0.05). Conclusion : Priming technique with rocuronium is effective method to shorten the onset of neuromuscular block. But priming dose of rocuronium itself could cause hypoxia and aspiration in awake patients and should be used carefully. Priming dose of rocuronium 0.06 mg/kg and 2 minutes interval maybe relatively safe method.

荳科采蔬의 栽培方法改善에 關한 硏究(第2報) : 강남콩의 品種特性比較 및 生長調節物質 處理에 依한 熟期調節 Evalustion of Bean Cultivars and Ways of Concentrating Pod Harvest by means of Chemical Sprays

李政明,李承雨,金侊來 경희대학교 부설 식량자원개발연구소 1982 硏究論文集 Vol.3 No.-

From the cultivar evaluation experiments conducted in 1981, 'Harvester' and 'Improved Tendergreen' (green-podded cv.) and 'Surecrop Stringless Wax' and 'Royal Burgundy' (yellow-podded cv.) were ranked high on the basis of total pod yield, pod to plant weight ratio, and shape. Number of root nodules per gram dry root varied considerably depending upon the cultivars. Among the cultivars tested, 'Topcrop' and 'Tendercrop' showed the highest nodule number. Ethephon 25-50 ppm, sprayed after considerable pod set, was effective in increasing once-over-harvested pod yield. Number of root nodules pet plant or per gram dry root was not influenced by the chemical sprays.

矮性강남콩 品種의 生育 및 뿌리혹 發生에 미치는 GA 및 SADH 效果

李政明,金侊來,鄭承龍 慶熙大學校 1980 論文集 Vol.10 No.-

Experiments were conducted to investigate the effect of GA and SADH on the growth and root nodule development of 5 bush-type snapbean cultivars. Plants were grown in 24-cm plastic pots from April to August, 1980, GA treatment increased shoot fresh weight and root dry weight, but decreased nodule number per plant and per unit root dry weight. SADG in-creased root dry weight and nodule number. SADH 1,000 ppm was most effective in increasing nodule number. Among the cultivars tested, 'Heuksando' showed the highest nodule number and 'Jinzu' the lowest. 'The effect of growth regulators varied considerably depending upon the cultivars tested.

荳科菜蔬의 栽培方法改善에 關한 硏究(第2報) : 강남콩의 品種特性比較 및 生長調節物質 處理에 依한 熱期調節 Evalution of Bean Cultivars and Ways of Concentrating Pod Harvest by means of Chemical Sprays

李政明,李承雨,金侊來 慶熙大學校 1982 論文集 Vol.11 No.-

From the cultivar evaluation experiments conducted in 1981, 'Harvester' and 'Improved Tendergreen' (green-podded cv.) and 'Surecrop Stringless Wax' and 'Royal Burgundy' (yellow-podded cv.) were ranked high on the basis of total pod yield, pod to plant weight ratio, and shape. Number of root nodules per gram dry root varied considerably depending upon the cultivars. Among the cultivars tested, 'Topcrop' and 'Tendercrop' showed the highest nodule number. Ethephon 25-50 ppm, sprayed after considerable pod set, was effective in increasing once-over-harvested pod yield. Number of root nodules per plant or per gram dry root was not influenced by the chemical sprays.

Characteristics in Separation of CCI₂F₂/Air Gas Mixture by Polyimide Membrane

이광래 江原大學校 産業技術硏究所 1994 産業技術硏究 Vol.14 No.-

폴리이미드 분리막에 의한 CC?F?/Air 혼합물의 분리특성에 관하여 온도, 압력, stage cut(θ), 주입기체 조성등의 영향을 규명하였다. 본 연구의 실험범위 내에서 이상분리인자(ideal separation factor)는 60-200이었으며, glassy polymer인 폴리이미드 분리막에 대하여 투과도가 높은 air의 투과도는 CCI?F? (dichlorodifluoromethane, CFC-12)에 의하여 상당히 감소함을 알 수 있었다. 그러나, 폴리이미드 분리막에 대한 투과도가 낮은 CC?F?의 투과도는 air에 의하여 투과도가 증가하였다. 또한, 수학적 모델에 의한 예측치가 실험치와 잘 일치됨을 알 수 있었다.

진정한 통일을 위한 제언 : 결혼이 곧 행복인가

이광래,임규정 군산대학교 현대이념연구소 1996 現代理念硏究 Vol.11 No.-

대학 체육교육과와 체육학과의 전공교육과정에 대한 비교연구 : 과목명칭과 학점 및 시간수를 중심으로

이광재,하명수,김윤래 江原大學校附設體育科學硏究所 1988 江原大學校附設體育科學硏究所論文集 Vol.- No.13

To identify the difference of Major Curriculum between Department of Physical Education in College of Education of both different department were compared as follows. Theoritical Subjects had more Score than Practical Skill, and elective Subjects had more score than required subject in a credit of Major subject. There was no differencies in the name of Subject. The numbers of credit according to theoritical area on major subject which consists more score than other major subjects were following orders; Teaching of P.E, Measurement and Evaluation of Physical Education, Health Education, and Sports Philosophy in P.E Dept. of Educational College. Sports Philosophy, Sports History, Measurement and Evaluation of P.E, and Administration of P.E in P.E Dept. of College of Sports Science. On the other hand practical skill of major subjects was following order. Ball Game, Gymnastics, Dance, and Tract and Field in both Department. But there is much more needs of course of study for handcapped.

소수성 알루미나막의 증기투과에 의한 에탄올의 분리

이상인,송근호,이광래 강원대학교 산업기술연구소 2000 産業技術硏究 Vol.20 No.A

The surface of porous alumina membrane was modified with silane coupling agent in order to enhance hydrophobicity. The contact angle of water to the surface-modified alumina membrane was greater than 90˚. The surface-modified membrane was tested in vapor permeation for the concentration of aqueous ethanol.With the increase of ethanol concentration in the feed, permeation flux increased due to the greater affinity of ethanol with surface-modified alumina membrane than that of water. The experimental results showed that the permeation rate of surface-modified alumina membrane was 15~1000 times greater than that of polymer membranes.