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Improving Product Quality through Conflict Management: A Study of Hong Kong ODM Suppliers
Lam, Ping-Kit,Chin, Kwai-Sang The Korean Society for Quality Management 2004 The Asian Journal on Quality Vol.5 No.2
Client-supplier collaboration in new product development (NPD) has been a strategy in response to fierce global competition. Traditionally, Hong Kong suppliers collaborate with worldwide clients through original equipment manufacturing (OEM) arrangement in which suppliers manufacture products according to clients' design. In recent years, a growing number of Hong Kong suppliers have transformed to original design manufacturing (ODM) in which they are assigned a design responsibility other than manufacturing products. The ODM arrangement necessitates a close interaction between clients and suppliers, which brings about intense conflict. Conflict has been recognized as an important factor affecting NPD performance including product quality. This paper studies the conflict handling practices of Hong Kong ODM suppliers based on 87 survey data. The results show that the suppliers frequently adopt effective conflict handling practices by which they can develop products of good quality through better design decisions. The results also suggest that the use of ineffective conflict handling behaviors, particularly avoiding, should be reduced for better product quality.
Lam, Ping-Kit,Chin, Kwai-Sang,Cheung, Wai-Ying The Korean Society for Quality Management 2006 The Asian Journal on Quality Vol.7 No.1
Client-supplier collaboration has been an imperative approach to new product development (NPD), in which a good product specification management system and practice is crucial to the assurance of product quality. This study investigates product specification management in client-supplier collaborative NPD. Based on the interviews and survey study, 12 problems and 13 good practices of product specification management are identified. It also compares the importance and degree of the implementation of the product specification practices in Hong Kong electronics industry. The results suggest that more intensive practices should be implemented for better product specification management.
Chan Mooi Kwai,Wai Wen Xuan,Ang Ruo Ping,Chew Ai Lan,Khoo Boon Yin 한국미생물학회 2020 미생물학회지 Vol.56 No.1
The expression of in-house DNA topoisomerase I (Topo1) was optimized in order to develop a gel-based DNA relaxation assay for the screening of potential bioactive compounds. Results showed that nearly 4-fold increment in total protein level was achieved in the culture supernatant with 1.0% (v/v) methanol feeding every 24 h and cultivated for 72 h at 28°C. Crude recombinant TopoI was shown to relax the supercoiled plasmid DNA completely in the developed gel-based assay and reactions were not affected by DMSO addition and the features on electrophoresed gel could be improved by chloroform: isoamylalcohol extraction. The recombinant protein was then purified and the enzymatic activity of the recombinant TopoI in the crude and purified culture supernatant was studied and compared with a commercial TopoI. DNA relaxation assay showed that the purified recombinant TopoI is a more reliable source with an activity of approximately 20~30 U/μl. The developed assay was finally evaluated by determining the inhibitory effects of flavonoids and positive control Camptothecin on the recombinant TopoI catalytic activity. The efficiency of the gel-based assay using purified recombinant TopoI was further evaluated against a cell-based cytotoxicity assay in which the inhibitory effects on cell growth by the flavonoids and Camptothecin were assessed. The similar inhibitory trends shown by both assays demonstrated that potential inhibitors can be preliminarily screened using a gel-based assay prior to identification of the inhibitors using a cell-based assay to detect the DNA intercalating agents that interrupt the TopoI catalytic activity.