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        Evaluation of the limit ice thickness for the hull of various Finnish-Swedish ice class vessels navigating in the Russian Arctic

        Kujala, Pentti,Korgesaar, Mihkel,Kamarainen, Jorma The Society of Naval Architects of Korea 2018 International Journal of Naval Architecture and Oc Vol.10 No.3

        Selection of suitable ice class for ships operation is an important but not simple task. The increased exploitation of the Polar waters, both seasonal periods and geographical areas, as well as the introduction of new international design standards such as Polar Code, reduces the relevancy of using existing experience as basis for the selection, and new methods and knowledge have to be developed. This paper will analyse what can be the limiting ice thickness for ships navigating in the Russian Arctic and designed according to the Finnish-Swedish ice class rules. The permanent deformations of ice-strengthened shell structures for various ice classes is determined using MT Uikku as the typical size of a vessel navigating in ice. The ice load in various conditions is determined using the ARCDEV data from the winter 1998 as the basic database. By comparing the measured load in various ice conditions with the serviceability limit state of the structures, the limiting ice thickness for various ice classes is determined. The database for maximum loads includes 3-weeks ice load measurements during April 1998 on the Kara Sea mainly by icebreaker assistance. Gumbel 1 distribution is fitted on the measured 20 min maximum values and the data is divided into various classes using ship speed, ice thickness and ice concentration as the main parameters. Results encouragingly show that present designs are safer than assumed in the Polar Code suggesting that assisted operation in Arctic conditions is feasible in rougher conditions than indicated in the Polar Code.

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        Evaluation of the limit ice thickness for the hull of various Finnish- Swedish ice class vessels navigating in the Russian Arctic

        Pentti Kujala,Mihkel K~orgesaar,Jorma Kamarainen 대한조선학회 2018 International Journal of Naval Architecture and Oc Vol.10 No.3

        Selection of suitable ice class for ships operation is an important but not simple task. The increased exploitation of the Polar waters, both seasonal periods and geographical areas, as well as the introduction of new international design standards such as Polar Code, reduces the relevancy of using existing experience as basis for the selection, and new methods and knowledge have to be developed. This paper will analyse what can be the limiting ice thickness for ships navigating in the Russian Arctic and designed according to the Finnish-Swedish ice class rules. The permanent deformations of ice-strengthened shell structures for various ice classes is determined using MT Uikku as the typical size of a vessel navigating in ice. The ice load in various conditions is determined using the ARCDEV data from the winter 1998 as the basic database. By comparing the measured load in various ice conditions with the serviceability limit state of the structures, the limiting ice thickness for various ice classes is determined. The database for maximum loads includes 3-weeks ice load measurements during April 1998 on the Kara Sea mainly by icebreaker assistance. Gumbel 1 distribution is fitted on the measured 20 min maximum values and the data is divided into various classes using ship speed, ice thickness and ice concentration as the main parameters. Results encouragingly show that present designs are safer than assumed in the Polar Code suggesting that assisted operation in Arctic conditions is feasible in rougher conditions than indicated in the Polar Code.

      • Differentiated Troy<sup>+</sup> Chief Cells Act as Reserve Stem Cells to Generate All Lineages of the Stomach Epithelium

        Stange, Daniel E.,Koo, B.K.,Huch, M.,Sibbel, G.,Basak, O.,Lyubimova, A.,Kujala, P.,Bartfeld, S.,Koster, J.,Geahlen, Jessica H.,Peters, Peter J.,van Es, Johan H.,van de Wetering, M.,Mills, Jason C.,Cle Cell Press ; MIT Press 2013 Cell Vol.155 No.2

        Proliferation of the self-renewing epithelium of the gastric corpus occurs almost exclusively in the isthmus of the glands, from where cells migrate bidirectionally toward pit and base. The isthmus is therefore generally viewed as the stem cell zone. We find that the stem cell marker Troy is expressed at the gland base by a small subpopulation of fully differentiated chief cells. By lineage tracing with a Troy-eGFP-ires-CreERT2 allele, single marked chief cells are shown to generate entirely labeled gastric units over periods of months. This phenomenon accelerates upon tissue damage. Troy<SUP>+</SUP> chief cells can be cultured to generate long-lived gastric organoids. Troy marks a specific subset of chief cells that display plasticity in that they are capable of replenishing entire gastric units, essentially serving as quiescent ''reserve'' stem cells. These observations challenge the notion that stem cell hierarchies represent a ''one-way street.''

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