Zn₁-xFexSe의 고유결함에 관한 연구

박남천,송재홍,채건식,오재근,김영국,손인호 慶南大學校 附設 基礎科學硏究所 1995 硏究論文集 Vol.7 No.-

We studied the native defects of dilute magnetic semiconductors Zn₁-xFexSe epilayer by using SAW device. The energy gap of Zn₁-xFexSe for each epilayer(x=0.0213, 0.0915) was 2.57eV, 2.74eV at room temperature (294K). The trap level for x=0.0213, 0.0915 were calculated by measuring Transverse Acoustoelectric Voltage(TAV). Also we can calculated cross section.

ZnSe의 광전압효과

박남천,채건식,김영국,설정식,손인호 慶南大學校 附設 基礎科學硏究所 1997 硏究論文集 Vol.10 No.-

We have measured the energy gap in ZnSe as a function of temperature by Laser-Generaeted Photocharge Voltage Spectroscopy(PVS). Trap levels were calculated quasi equibrium, peak shape, initial rise methods. And We have measured the Photocharge Voltage as a function of temperature with varing heating rate. The trapping cross-section of ZnSe was calculated by the methods of Grossweiner.

직업적인 납 노출이 없는 일부 중년 한국인의 골중납량 및 혈중납량

김남수,최성우,김진호,함정오,박해윤,안규동,이병국 大韓産業醫學會 2007 대한직업환경의학회지 Vol.19 No.4

목적: 우리나라에서 납에 직업적으로 노출되지 않은 일부 중년 성인들의 골중납량과 혈중납량의 수준과 상호관련성을 알아보기 위하여 40세 이상 남자 86명 여자 51명 총 137명을 대상으로 본 연구를 시도하였다. 방법: 연구변수로 골중납량인 경골납량,혈중납량을 택하였다. 경골납량은 K-shell XRF를 이용하여 각 대상 자들을 30분간 측정하였고,혈중납량은 원자흡광광도계법으로 분석하였다. 결과: 총대상자 137명의 경골납량의 평균±표준편차는 3.49±4.99 μg/g이었으며, 남자와 여자는 각각 3.90± 4.88 μg/g 및 2.80±5.14 μg/g이었으나 양군 평균의 통계적 차이는 없었다. 한편 총대상자 137명의 혈중납량의 평균±표준편차는 3.70±1.35 μg/dl이었으며,남자와 여자는 각각 3.93±1.25 μg/dl 및 3.30±1.42 μg/dl이었으나 양군 평균의 통계적 차이는 없었다. 음주,흡연 및 BMI를 통제한 후 혈중납량을 종속변수로 한 중 회귀분석에서 연령은 양의 영향을 주는 변수로 나타났다. 여자대상자만을 대상으로 한 중 회귀분석에서 교란변수를 통제한 후 연령은 경골납량에 경계수준의 양의영향을 나타내었다. 결론: 40세 이상의 우리나라 중년성인의 경골납량의 평균±표준편차는 3.49±4.99 μg/g이었으며,혈중납량의 평균±표준편차는 3.70±1.35 μg/dl이었다 혈중납량은 연령과 성과 유의한 양의 관련성이 있었으나,골중납량은 여자에서만 연령과 경계수준의 유의한 관련을 나타냈다. Objectives: In order to investigate the level and the association between bone lead and blood lead levels of non-occupationally, lead-exposed Koreans, the authors studied the lead biomarkers of 137 middle aged Koreans (86 males and 51 females) older than whose age were above 40 years. Methods: The tibia lead level was selected as the bone lead indicator of cortical bone, and the blood lead level was also measured. The tibia lead level was measured by K-shell XRF with 30-minute measurement of each subjects. The blood lead level was analyzed by AAS method. Results: The mean (SD) of the tibia lead level of the 137 study subjects was 3.49 (4.99) ,㎍/g, and tended to be higher. The mean (SD) of tibia lead level in male subjects (was 3.90 (4.88) ㎍/g) and larger than in that of female subjects (2.80 (5.14) ㎍/g), but without no statistical significance was observed. The mean (SD) of blood lead level of all total subjects was 3.70 (1.35) ,㎍/dl, and tended to be higher. The mean (SD) of blood lead level in male subjects (was 3.93 (1.25) ㎍/dl) and larger than in that of female subjects (3.30 (1.42) ㎍/dl), but without no statistical significance was observed. In multiple regression analysis of blood lead levels after adjusting for covariates, age was a significant independent variable. A weak association of age with tibia lead in female subjects was also observed in multiple regression analysis. Conclusion: The mean (SD) of tibia and blood lead levels of middle aged Koreans whose ages were over 40 years old were 3.49 (4.99) ㎍/g and 3.70 (1.35) ㎍/dl, respectively. Age and sex were positive predictors of blood lead level in multiple regression analysis after controlling for the covariates. However, in multiple regression analysis whereas age was weakly association with tibia lead level only in female subjects in multiple regression analysis.

진행된 HIV 감염 환자에서 십이지장의 미란성 병변으로 발현한 Mycobacterium genavense 감염 1예

진상만,박종선,김홍빈,오명돈,최강원,김희연,국윤호,김남중 대한감염학회 2007 감염과 화학요법 Vol.39 No.4

Mycobacterium genauense는 최근에 알려진 미코박테륨으로서, 식욕 부진, 체중 감소, 설사, 림프절 병증 등 파종성 Myocobacterium avium-intracellulare complex 감염과 유사한 임상상을 보이며, 위장관 침범을 잘 하는 것으로 알려져 있으나 아직 국내에서 증례는 보고된 바가 없다. 저자들은 진행된 HIV 감염 환자에서 십이지장의 미란성 병변으로 발현한 Mycobacterium genavense 감염 1예를 경험하였기에 문헌 고찰과 함께 보고하는 바이다. 환자는 상복부 동통과 발열, 설사로 내원하였다. 십이지장의 미란성 병변에서 시행한 조직검사에서 항산균이 가득 차있는 거품세포가 관찰되었으며, 이 검체에서 16S rRNA 유전자의 중합연쇄반응 검사를 시행하여 Mycobacterium genavense를 확인하였다. Mycobacterium genavense, first identified in 1990, is known as a pathogen that mimics disseminated Myocobacterium avium-intracellulare complex (MAC) infection with particular propensity for the gastrointestinal tract. In Korea, no case with the organism has been reported. Herein we report a case of Mycobacterium genavense infection that manifested with erosive lesion of duodenum in a patient with acquired immune deficiency syndrome. The patient presented with epigastric pain and fever, diarrhea. Duodenal biopsy showed histiocytic infiltration with numerous acid-fast bacilli. Identification of the mycobacterial isolate by the polymerase chain reaction restriction analysis of 16S rRNA gene revealed Mycobacterium genavense.

압전박막공진기 설계 및 제작

김인태,박윤권,김용국,이윤희,이전국,김남수,주병권 경북대학교 센서기술연구소 2002 센서技術學術大會論文集 Vol.13 No.1

원격 영상 정보 시스템의 개발

김선호,유선국,김용구,박성욱,김성림,김남현 대한의료정보학회 1996 Healthcare Informatics Research Vol.2 No.1

골내 고정 장치용 초내식성 오스테나이트 및 듀플렉스 스테인리스강 가공재의 특성

오근택,강국진,박용수,김경남 大韓齒科器材學會 2003 대한치과재료학회지 Vol.30 No.3

Nickel is one of the most common causes of allergic contact dermatitis and hypersensitivity. In case of stainless steel as biomaterials, the higher the corrosion resistance and the lower the nickel content, the better it is or the human body. However, because nickel plays an essential role in the stabilization of the austenitic phase and the corrosion resistance of stainless steel, it is difficult to remove the nickel from the constituents of stainless steels completely. Therefore, the purpose of this study was to investigate corrosion resistance, cytotoxicity, and mechanical property of super stainless steels, which had high corrosion resistance by synergistic effect of Mo(or W) and N, with respect to nickel content and to evaluate their potential for orthodontic applications. Super austenitic stainless steel(SR-50A) had high nickel content of 22% and super duplex stainless steels nickel contents of 6~10%. Super austenitic and duplex stainless steels had nitrogen contents of above 0.2%. Also, these steels had high Mo or W contents which were able to increase the localized corrosion resistance. In terms of hardness, super stainless steels, which had Vickers hardness values of 374~400 Hv in cold-rolled state and 186~285 Hv in annealed state, exhibited higher values than 316L S. S.. Duplex stainless steels exhibited higher mechanical properties than austenitic stainless steels. In terms of corrosion resistance, super stainless steels exhibited lower passive current density(2.3~3.8 ㎂/cm^2) than pure Ti(6.6㎂/cm^2) in the body-simulated solution and similar potentiodynamic polarization behaviors. Pitting corrosion occurred in 316L S. S. but not in the others. Thus these steels were considered to have high corrosion resistance in the human body. In terms of cytotoxicity, SR-5OA and SAF2507 exhibited none cytotoxicity and the others slight. This results indicated that the cytotoxicity of alloys containing nickel had no relation with nickel content because SR-5OA with the highest nickel content exhibited none cytetoxicity In conclusion, it is considered that super stainless steels with high corrosion resistance and good biocompatibility can be used for orthodontic applications because of the enhanced passive film by high addition of Mo, W, N, etc.

골수구성 백혈병 환자에게 발생한 결핵성 림프절염

이창섭,송진수,최평균,조재현,방지환,박경화,박완범,김홍빈,김남중,윤성수,박선양,김병국,오명돈,최강원 대한감염학회 2006 감염과 화학요법 Vol.38 No.5

혈액질환 가운데 결핵 발생이 증가한다고 알려진 것은 호지킨 림프종을 포함한 림프증식성질환 그리고 모양세포성 백혈병 등이 있다. 또한 동종 골수이식을 받은 환자에서도 결핵은 증가한다고 알려져있다. Kaplan 등은 골수구성 백혈병 환자에서 결핵 발생이 증가한다고 보고하였다. 그러나 골수구성 백혈병 환자에서 결핵의 발생이 증가하는 이유에 대해서는 아직까지 정확하게 밝혀지지 않았다. 저자들이 2년 동안 후향적으로 조사한 180명의 성인 골수구성 백혈병 환자들 가운데 결핵이 발생한 환자는 4명이었고, 발생 부위는 모두 림프절이었다. 결핵은 골수구성 백혈병의 특정 아형에만 국한되어 발생하지 않았지만, 50%에서 FAB 분류에 의한 M4였다. 림프절이 종대된 골수구성 백혈병 환자에서 특히, 결핵의 유병율이 높은 나라에서는 결핵성 림프절염도 감별진단에 포함시켜야 한다. During the neutropenic phase, leukemia patients receiving chemotherapy are prone to bacterial and, fungal infections; occasionally mycobacterial, viral and protozoal organisms may also cause infections. Mycobacterium tuberculosis infection was reported very rarely in these patients. This report describes four patients with M. tuberculosis infection identified from 185 adult patients who were diagnosed myelogenous leukemia between January 2003, and December 2004. There was no patient with M. tuberculosis infection from 44 lymphoid leukemia and 11 acute biphenotypic leukemia patients. Sites of infection were all lymph nodes. Three among four patients were presented with lymphadenopathy at initial diagnosis of leukemia, and the other one presented with lymphadenopathy after induction chemotherapy. There was no patient presented with lymphadenopathy during the neutropenic phase. Tuberculous lymphadenitis was presented in a patient with three acute myelogenous leukemia (FAB class 2 M4, 1 M2) and a chronic myelogenous leukemia, accelerated phase. An acute myelogenous leukemia patient had a leukemic cell and tubercle bacilli in the same lymph node. Tuberculosis should also be included as a differential diagnosis in myelogenous leukemia patient with lymphadenopathy, especially in the countries in which the disease is endemic.

Role of a Burr Hole and Calvarial Bone Marrow-Derived Stem Cells in the Ischemic Rat Brain : A Possible Mechanism for the Efficacy of Multiple Burr Hole Surgery in Moyamoya Disease

Nam, Taek-kyun,Park, Seung-won,Park, Yong-sook,Kwon, Jeong-taik,Min, Byung-kook,Hwang, Sung-nam The Korean Neurosurgical Society 2015 Journal of Korean neurosurgical society Vol.46 No.6

Objective : This study investigates the role of a burr hole and calvarial bone marrow-derived stem cells (BMSCs) in a transient ischemic brain injury model in the rat and postulates a possible mechanism for the efficacy of multiple cranial burr hole (MCBH) surgery in moyamoya disease (MMD). Methods : Twenty Sprague-Dawley rats (250 g, male) were divided into four groups : normal control group (n=5), burr hole group (n=5), ischemia group (n=5), and ischemia+burr hole group (n=5). Focal ischemia was induced by the transient middle cerebral artery occlusion (MCAO). At one week after the ischemic injury, a 2 mm-sized cranial burr hole with small cortical incision was made on the ipsilateral (left) parietal area. Bromodeoxyuridine (BrdU, 50 mg/kg) was injected intraperitoneally, 2 times a day for 6 days after the burr hole trephination. At one week after the burr hole trephination, brains were harvested. Immunohistochemical stainings for BrdU, CD34, VEGF, and Doublecortin and Nestin were done. Results : In the ischemia+burr hole group, BrdU (+), CD34 (+), and Doublecortin (+) cells were found in the cortical incision site below the burr hole. A number of cells with Nestin (+) or VEGF (+) were found in the cerebral parenchyma around the cortical incision site. In the other groups, BrdU (+), CD34 (+), Doublecortin (+), and Nestin (+) cells were not detected in the corresponding area. These findings suggest that BrdU (+) and CD34 (+) cells are bone marrow-derived stem cells, which may be derived from the calvarial bone marrow through the burr hole. The existence of CD34 (+) and VEGF (+) cells indicates increased angiogenesis, while the existence of Doublecortin (+), Nestin (+) cells indicates increased neurogenesis. Conclusion : Based on these findings, the BMSCs through burr holes seem to play an important role for the therapeutic effect of the MCBH surgery in MMD.

Project Management Current For Nuclear Research Facility

Park Kook-Nam,Wu Sang-IK,Oh Soo-Youl,Lim In-Cheol 대한산업공학회 2012 대한산업공학회 추계학술대회논문집 Vol.2012 No.11