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Maxillary anterior single implant prosthesis ; a clinical case
Kim Seung-June,Kwon Kung-Rock,Lee Sung-Bok,Woo Yi-Hyung,Choi Dae-Gyun,Choi Boo-Byung The Korean Academy of Prosthodonitics 2001 대한치과보철학회지 Vol.39 No.3
Achieving an aesthetic implant-supported restoration in the single tooth missing case can be challenging when the implant site is in e anterior region. The objective of this report is to focus on presurgical evaluation of implant site and systematic development of related prosthetic modalities. An accurate diagnostic evaluation, a systematically developed pesurgical plan, and knowledge and clinical skill of the various related therapeutic modalities are indispensible. Collection of patient's information, appropriate abutment selection, soft tissue contour, implant axis, and occlusion need to be discussed for aesthetic clinical outcome. For aesthetic restoration, such as surgical guide stent for precise implant positioning customized provisional restoration for development of optimal periimplant soft tissue contours, and fabrication customized abutment (mesiostructure) for veriable emergence profile, are recommended.
Prognostic Value of Pre- and Post-Treatment FDG PET/CT Parameters in Small Cell Lung Cancer Patients
Kim, Hyoungwoo,Yoo, Ie Ryung,Boo, Sun Ha,Park, Hye Lim,O, Joo Hyun,Kim, Sung Hoon 대한핵의학회 2018 핵의학 분자영상 Vol.52 No.1
Purpose To evaluate the prognostic value of PET parameters obtained from pre- and post-treatment FDG PET/CT examinations in patients with SCLC. Methods Fifty-nine patients with initially diagnosed SCLC from 2009 to 2014 were included and had chemotherapy and/or concurrent chemoradiotherapy. FDG PET/CT examinations were performed before (PET1) and after (PET2) treatment to evaluate treatment response. A region of interest was placed over the primary lesion and metastatic lymph nodes within the thoracic cavity. PET parameters including change from PET1 to PET2 (${\Delta}$ in %) were acquired: SUVmax, SUVpeak, MTV2.5, TLG, ${\Delta}SUVmax$, ${\Delta}SUVpeak$, ${\Delta}MTV$ and ${\Delta}TLG$. Patient characteristics including staging, age, sex, LDH and response evaluation by RECIST were surveyed. Statistical analysis was done using Kaplan-Meier method and Cox regression analysis with respect to OS and PFS. Results The median follow-up was 9.6 months (2.5-80.5 months). 27 patients were LD and 32 were ED. Forty-six patients (78.0%) had died, and median OS was 8.6 months; 51 patients (86%) showed disease progression, and median PFS was 2.5 months. On univariate analysis, patients with ED, high interval change (${\Delta}SUVmax$ and ${\Delta}SUVpeak$) and low PET2 parameters showed longer OS and PFS. Multivariate analyses demonstrated that ${\Delta}SUVpeak$ (HR 2.6, P = 0.002) was an independent prognostic factors for OS, and MTV2.5 of PET2 (HR 2.8, P = 0.001), disease stage (HR 2.7, P = 0.003) and RECIST (HR 2.0, P = 0.023) were independent prognostic factors for PFS. Conclusions Metabolic and volumetric PET parameters obtained from pre- and post-treatment FDG PET/CT examinations in patients with SCLC have significant prognostic information.