CATCH22의 분자유전학적 특성에 관한 연구

길홍량,이영하,정용헌 충남대학교 의과대학 지역사회의학연구소 2000 충남의대잡지 Vol.27 No.2

To investigate molecular genetic characteristics of CATCH 22 syndrome, we studied the correlation between phenotype and target gene screening and mode of inheritance using FISH (fluroscence in situ hybridization) and STRP(short tandem-repeated polymorphism). Hemizygosity for a region of 22q11.2 was found in 21 CATCH 22 patients. 2 of 19 family (11%) had familial CATCH 22 syndrome and affected 2 parents were mothers. No familial cases were found among CATCH 22 syndrome with absent thymus/ DiGeorge syndrome. The conotruncai cardiac anomalies such as Tetralogy of Fallot and vascular anomalies were common among CATCH 22 syndrome. Both the STRP maker screening(D22S941) and FISH(D22S75) were efficient and useful for the detection of chromosome 22q11 deletion and the evaluation of parent of origin but show some heterogeniety. Markers D22S75 and D22S941 appear to be consistently hemizygous in patients with deletions, so it was very useful in screening the patients with the conotrucal cardiac anomalies.

生産性을 考慮한 切削加工에 對한 最適切削條件의 自動選定에 關한 硏究

李吉雨,金泳祥 홍익대학교 산업기술연구소 1996 産業技術 Vol.6 No.-

In recent years machining turns to flexible manufacturing. Industry in machining requires to increase machining productivity and to reduce costs. To adapt this trend it is necessary to optimize machining condition Even though many researches in this are introduced various way to set the optimal condition, still there are not enough. Therefore this research was done to select the optimal cutting condition for industry, and to develope the computer program to select the optimal cutting condition automatically. Also, this program was applied to many companies, and compare costs per minute. The results of this research will contribute to increase machining productivity of various companies with the automatic selection of optimal cutting condition.

불감시간이 있는 공정의 저차 이산시간 모형과 제어

이광원,고영길,원종남 亞洲大學校 1985 論文集 Vol.8 No.-

For the process with dead time, a low-order discrete-time modeling method is suggested and a digital predictor-controller has been developed. It is easy to adjust the model parameters under a different sampling rate and controller tuning is possible on the spot. A simple predictor is presented, which removes the dominant pole of the process.

인성연구의 최근 동향 : Analysis of the Research Sabjects and Evaluation Instruments 연구주제 및 평가도구별 분석

전영길,정영애,양병한 창원대학교 학생생활연구소 1995 학생생활연구 Vol.8 No.-

意思決定論序說 : 規範的 理論模型

權寧贊,朴英熙,尹正吉 건국대학교 1975 學術誌 Vol.19 No.1

Decision making is one of the most important functions of administrators and it is a key element of management functions which is "to determine what you want people to accomplish, to check periodically on flow well they are accomplishing it, and to develop methods by which they well perform more effectively". In other words, deciding what to do, and how to do it, is then, the heart of the management function. The purpose of this paper is writing the teat book of the theory and the pratice in decision-making. But we only paid the attention on introducing and analysing some normative models of public policy making because of limiting time and volume here. An important thought relatively new and less developed addition to the formal line of organizational analysis is the study of organizational decision-making. The theory of decision-making is at present largely a non-organizational theory that deaths with decisions made by individuals, disregarding whether the individuals are card players, shoppers in a supermarket, or executive. Moreover, like the classical administrative approach, decision-makings theory in large part is prescriptive ; i.e., it indicates-often on the basis of mathematical analysis and logical reasoning, sometimes on the basis of "distilled common sense"-what steps a decision-mailer should follow if he wishes to make rational decision. However, in recent years there has been growing interest in a descriptive theory of decision-making which reports and analyzes how people actually make decisions, what prevents them from making rational ones, and under what conditions they will make comparatively rational decisions. The descriptive approach still requires considerable development and needs to be extended from the individual to the organization level. According to Yehezkel Dror's classification in this paper, we concentrated on six main normative models that deal with phases of policy-making: (1) the pure-rationality model: (2) the "economically rational" model; (3) the sequential-decision model; (4) the incremental-change model: (5) the satisfying model; and (6) the extrarational-processes model. In this paper, we have described and critically analyze these six nomative models one by one, paying special attention to the assumptions on which they are based, to their domains of validity, and to their major limitations. To bun up, Dror analyzed the previous sirs normative models and he constructed his own optimal normative model of policy-making which had mixed the "economically" rational model and the extrarational model. The optimal model of public policy making tries to reject pure rationality on the one hand, and to provide an optimal goal that is more than an incrementally improved extrapolation of the present situation on the other hand. Dror intended the optimal model to be both an analytical tool for understanding policy-making and a goal that actual public policy making can approximate if the policymakers are willing to try. It should be judged not as an end in itself, but only as an operational tool, that is, by its usef71ness for analyzing, evaluating, and improving public policy-making. All five of the normative models except the extrarational model discussed above share one basic assumption, namely, that purse rationality, when it can be achieved at a reasonable cost, is the best method for decisionmaking and policymaking. The differences between the pure-rationality model and the other four are not in their basic assumptions but in the way they estimate the practicality and justification for a pure-rationality policy in terms of benefits arid costs. The economically rational model deviates from pure rationality because it accepts the restraints that limited resources put on trying to achieve pure rationality. The sequential-decision model in effect proposes a new type of policy making strategy to be considered by pure-rationality and economic피Iy rational standards. The incremental change model deviates from pure rationality on the grounds that innovative policies are necessarily risky and unpredictable, and that the unexpected results of such policies will likely be very costly. The satisfying model deviates from pure rationality on the grounds that, fur social-psychological reasons, policymakers do not look for new alternatives after they have found one they consider satisfactory. But all these models are clearly derived from the pure-rationality model, are themselves justified in terms of "pure rationality," and are presented as realistic second-bests to the unachievable ideal, pure rationality. The model that is exactly opposite to the pure-rationality model is therefore not one of these four models. It is rather the extrarational model, whose various forma are based on some acceptance of extrarational processes as an optimal method for decisionmaking and policymaking. A normative model of public policymaking exists as a tool for systematically analyzing public policymaking, as a basis for the criteria and standards needed to evaluate policymaking, and as a guide for formulating effective proposals for any improvements that are found to be desirable. Such a model should be normative, not in the sense of setting forth final goals, but in the instrumental sense of establishing processes and structures whereby a maximum net output of whatever coals and values are desired can be achieved. In contrast, a non-normative behavioral model is good enough for analyzing policymaking, but to make improvements in policymaking, one needs a model which is suitable not only for scientific analysis of actual behavior, but also for evaluating that behavior, and for deriving suggestions for improving that behavior. The normative model must therefore also be idealistic enough that it can stimulate consistent, through-going proposals for innovative improvements based on the best available knowledge. Insofar as the normative model used to evaluate public policymaking is either too utopian or too realistic, it will lead to a picture that is either too dark or too bright, respectively, neither picture being much good for deciding how to improve the situation. Dror's optimal model of public policymaking has a characteristics of avoiding both extremes deseribed above.

J.J. Rousseau의 哲學과 體育思想의 理解

金隆吉,孫俊丘 대구대학교 인문과학연구소 1994 人文科學硏究 Vol.12 No.-

purpose of this paper are to understand J.J Rousseau, as a pioneer of modern liberal education, and his profound philosophy and physical education, to compare modern physical education to this theory, and to review the present sports problems. In order to these, preferencialy Roussear's lifetime and idea are analized, and reviewed the making process of his philosophy, then understanded true educational theam in the view of physical education philosophy. Therefore, it can be perceived the following in order to surmount the confussion of substances and the aim of sports, and overcome present situation that issubstandcial distortion or the loss of humanism. First, Rousser emphasised on a physical trainning for thinking faculty and ethnic usefulness. It shoud be perceived the coordinates that might be perceptional transition of physical value and the trend of present education, because of the aims of present education might be the entrance into a school of higher grade and neglect the intercorelation among inteligency, vitue, and physique as if they are all. Second, another purpose of physical trainning of naturalism emphasises the disciplinsm that could be perceived the key point of physical trainning and health for present people in industrialized society, also it coud be reperceived its value and teaching instruction. Third, it shoud be received as warnin for spreading the neglected juvenile's personality. interest, and development stage. As result of "everything according to nature ······" Roussreu's instruction method of juvenile development stage in the view of his basic philosophic creed is the mean that changed the situation which everone only concerns of a result and a uniform instruction. Last, according to Rousseau's philosophy as ideal educational standard for fighteous humanism, that is, "natural man" means true health and sportsmanship, it shoud be received the severe article that deep comprehension and love between teacher and student is extincted. the pursuit of learning and personality are divied. and there exsist only transaction and loss of humanism between them.

칸디다 질염에 대한 경구용 Fluconazole(Diflucan) 1회 요법의 임상적 평가

강길전,김영범 최신의학사 1991 最新醫學 Vol.34 No.10

Socrates의 철학이 체육사상에 미치는 영향

김명미,김융길 한국스포츠리서치 2003 한국 스포츠 리서치 Vol.14 No.2

The purpose of this study is to examine the interrelation between Socrates' life and physical education. In the history of physical education, physical idea was discussed widely whether objective aspects or subjective aspects through the process of human society. Socrates thought that although soul man's master, body is his servant, this is based on the theory of Socrates idea which is soul and body are one Socrates insisted that the whole person formed through physical training is very valuable because he could gain happy and satisfaction from biological and physiological development. Socrates shows his concept of individual human perfection and relates it of social and mental perfection in his Greek period. Socrates discards all the dogmas of revealed formation which represent luxury and extravagance and believes only that people will have health when they are fully mature between soul and body. Therefore his concept of perfection is the harmony of soul and body in order to approach his concept, Socrates already talks with young men and is wondering without shows. In the end Socrates recognized goodness on the basis of intellectual reliance and finally reached to the true self identity through the insight and reflection According to "know yourself" which is the matter of Socrates life, Socrates awakes himself all the time.

熱處理에 의한 양배추 시들음병 防除

張田益,秦石天,文英仁,姜榮吉 제주대학교 아열대농업연구소 2000 亞熱帶農業硏究 Vol.17 No.-

This study was conducted to evaluate the efficacy of soil heating treatment for the control of cabbage yellows. The results obtained are summarized as follows ; 1.The density of Fusarium oxysporum was not changed with time at room temperature while it was not isolated 25 and 5 days after the heating treatment of 35 and 40℃, respectively. However any of it was not detected above 45℃. 2.When cabbage was grown in the soil inoculated with the pathogen after the inoculated soil was incubated for 1, 3, 5 and 7 days at 45℃, Fusarium oxysporum wilt was not observed for cabbage grown in the soil incubated for more than 3 days. 3.Pseudomonas sp. and Bacilus sp. antagonists that show antifungal activity to were Fusarium oxysporum in petri dish assays were isolated. The growth temperature of Bacillus sp. was higher than that of Fusarium oxysporum.

太陽熱 消毒에 의한 양배추 시들음병 防除 效果

張田益,秦石天,文英仁,姜榮吉 제주대학교 아열대농업연구소 2000 亞熱帶農業硏究 Vol.17 No.-

This study was conducted to evaluate the efficacy of soil solarization, alone and combined with various treatments for the control of soil-borne diseases of cabbage at Cheju from 1988∼ 1999. The results obtained are summarized as follows ; 1.The average of maximum soil temperature at the l0cm depth under soil sruface from Aug. 4 to Sept. 3, 1998 were 6.5℃ higher under polyethylene(P.E.) film mulch compared with 35.4℃ of control. The maximum soil temperatures of above 40℃ at the 10cm depth were recorded for 23 days in the P.E. film mulch. 2.The infection rate of F. oxysporum wilt of cabbages grown after the treatment of disinfector dazomet+P.E. film mulch, was lowest, followed by manure+P.E. film mulch, and alone P.E. film mulch. 3.The leaf length of cabbages grown after P.E. film mulch were greater compared with untreated control but head weight showed no difference between P.E. film mulch and control.