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加味香砂六君子湯이 생쥐 小腸에서 放射線照射 後 保護效果와 Apoptosis에 미치는 影響
이태업,김진성,윤상협,류봉하,박동원,류기원 대한한방종양학회 2000 대한한방종양학회지 Vol.6 No.1
The present study was performed in order to evaluate the effects of the gamihyangsayukgunjatang on radioprotection and apoptoss in small intestines of mice after whole bdy irradiation. Two hundred forty mice were divided into 40 groups according to the radiation dose and the gamihyangsayukgunjatang treatment. The extracts of the herbal medicines were orally administered to each group differently before and/or after irradiation. The gamihyangsayukgunjatang treated groups were divided into 3 groups. Sample Ⅰ was the group treated with the gamihyangsayukgunjatang for 3 days before the radiation, sample Ⅱ was the group treated with the gamihyangsayukgunjatang for 3 days after the radiation. Sample Ⅲ was the group treated with the gamihyangsayukgunjatang for both 3 days before and after the radiation. To analyze the crypt survival, the micradony survival assay was used according to the Withers and Elind's method. To analyze the apptosis, the TUNEL assay was done. The reslts obtained are a follows : 1. From the microcolony survival assay, the gamihyangsayukgunjatang treated groups showed theradioprotective effect with a statistical ignificance(p<0.05), as compared to the control group. Comparing the radioprotective effect among the 3 groups, sample Ⅲ was statistically more significant than sample Ⅰand Ⅱ (p<O.O5). Sample Ⅰ showed no effect. In accordance with the research mentioned above, it is suggested that the radioprotective effect of the gamihyangsayukgunjatang is more useful for the treatment of the radiation injury rather that the prevention. 2. The results of the TUNEL assay showed that the apoptotic index in the gamihyangsayukgunjatang treaed group was slightly decreased with no effectiveness, as compared to the control group. According to the above results, it could be suggested that the gammyangsayukgummang has a prominent protective effect in mice intestines against the radiation damage. However, the radioprotective effect does not seem to be related to inhibition of the apoptosis.
최정태,안무업,안희철,최영미,정재봉,서정열,유기철,이삼우,박석현,조준휘,김성환,김아진,송근정 대한응급의학회 2001 대한응급의학회지 Vol.12 No.4
Purpose : This study was conducted to develop field triage, transportation, distribution, and prehospital care at a fire disaster by analyzing the victims of the fore that broke out at a bar in Incheon. Method : We analyzed the cases of the victims of a fire in Incheon in Oct. 1999. We determined the primary care hospital, the arrival time, the burn size, the outcome, and the injury type from the medical records, the concerned organ records, and interviews with concerned persons. Result : The total number of victims was 137: 56 prehospital deaths, 1 hospital death, and 80 survivals. The Pearson correlation coefficient between the burn size and the severity was -0.175. There were 121(89.6%) cases of inhalation injury, 59 (43.7%) cases of flame burns, 66 (48.9%) cases of hypoxic brain damage, and 16 (11.9%) cases involving other types of injury. Conclusion : The causes of death of the fire victims were inhalation injury and hypoxic brain damage due to CO poisoning and other toxic inhalants. We propose the use of a simple triage and rapid treatment(START) system and a reassessment the delayed category in fire disasters.
Ki Young Kim,Jung Mo Lee,Chang-Eob Baag,Wooil M. Moon,Heeok Jung,So Young Lee 한국지질과학협의회 2007 Geosciences Journal Vol.11 No.3
In order to reveal the perspective of velocity struc-ture in the southern part of the Korean peninsula, a seismic exper-iment was carried out along a WNW-ESE profile of 294-km lengthin December, 2002. In 100-m deep dril-holes, seismic explosives of1000 and 500 kg were detonated on the west coast and near thecenter of the profile, respectively. The seismic signals were detectedby 198 portable seismometers spaced approximately at an 1.5 kminterval and digitally recorded for 115 s at an 120-Hz samplingrate. Normal moveout corrections were applied to yield reflectionimages for P, S, and PS converted waves followed by time-to-depthconversion through forward modeling of travel times using thefourth-order equation for wide angle reflections. Three distinctreflection events are identified at average two-way travel times ofTheir converted depths are 13.71, 23.37, and 33.67 km, respec-tively, and the P-wave interval velocities betwen the depth bound-aries including the free surface are 5.60, 6.19, and 6.96 km/s fromtop to bottom. The reflection Moho is imaged as a sharp boundaryin the midle of the profile while multi-layers are featured nearboth ends of the profile.
울산 남부 초등학교 계단사고에서 발생한 압좌손상의 고찰
안무업,유기철,송근정 대한응급의학회 1997 대한응급의학회지 Vol.8 No.4
Background: Fatal events have shown us how very easily a mass of human beings may asphyxiate themselves. An accident of this type happened March 3, 1997 at Nambu primary school in Ulsan. We analyse this incident to supply basic data for crowed disaster planning. Method: We conducted a sruvey at the scene of the accident and two hospitals at which the patients were admitted. We interviewed victims, victim's family, and rescuers. We analysed several aspects: prehospital management, in hospital management, traumatic and crush asphyxia symptom, and management of patients with changes in mental status. Results: One child died and 10 children were injured. The mean ISS(injury severity score) and RTS(reviced trauma score) was 4.6 and 11.3 respectively. 8 cases of traumatic and crush asphyxia was occurred. And, the seven out of 10 patients suffered changes in mental status. Conclusion: It is importmant to understand at crowd disaster that the injured persons require basic airway care and breathing support as rapidly as possible, prior to any other managements and studies.
실물화재실험을 통한 화재현장 피해자의 일산화탄소와 저산소증에 의한 손상예측
안무업,유기철,송근정 대한응급의학회 1997 대한응급의학회지 Vol.8 No.4
Background: The fire victims are affected not only by burn and trauma but also carbon monoxide(CO) and hypoxia. It may be useful to triage mass casualties of fire field tht preestimate the victim's injury sevrrities by experiments of measuring the concentration of CO and oxygen according to time progression. Method: We prepared one house of apartment as like usual residental environment. The mesuring of concentrations of CO and oxygen was started from firing. Result: 3.8 Min. after firing: CO concentration(0.007%) was reached to the level that can give rise to spontaneous headache, 5 Min: The concentration of CO was increased. At this level(0.0012%), the victims of fire may be suffered severe headache inspite of mild movement. 5.5 Min: At this time, 0.02% of CO concentration that the victims can't escape by themselves was checked. 6 Min: 0.08% was measured, most patients may be unconscious and the symptoms will be more severe at this CO concentration because of hypoxia. 6.4Min: It was absolutly impossible to be survival at this time due to incresing of CO concentration(0.195%) and decreasing of O2 concentration(5%). Conclusion: It is within 5.5 Min. that the patient can escape by themselves, and impossible to be survival more than 6.5 Min. in fire field. Rescuers and EMTs must consider time factor as well as sysmtoms of patients.
류재만,엄기일,김잉곤,홍승업 大韓成形外科學會 1995 Archives of Plastic Surgery Vol.22 No.6
Double eyelid operation is the most frequent method for cosmetic purposes in Korean women. It is believed that beautiful eyes have wide apertures, thin lids, naturaly looking folds of proper width and length, without epicanthal folds, under the influence of western culture. Double eyelid operations are classified into an in-fold type and an out-fold type. The in-fold type is a common operation method with a more naturaly looking result. However, the medial side of the fold is too shallow and low sided due to the epicanthal fold. The out-fold type is prominent and brisky but this result is an unnatural fold of the medial side due to the epicanthal fold. From september, 1992 to January, 1995 we have performed 52 cases of double eyelid operations in oriental women using procedures in which epicanthal fold excision and medial canthal fixation were performed. The patients' ages ranged from 13 to 49 years. (mean : 22.3 yr. old). There were 5 males and 47 females. After thorough follow-up (mean : 18.3 mo.), 50 cases showed excellent results, providing a wide lid aperture, reduced intercanthal distance, naturaly looking attractive folds of proper width and length without epicanthal folds.