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대학교 축구선수와 일반학생들의 심폐기능에 관한 비교 연구
고기채,이재문,석서규 경희대학교 체육과학연구소 1997 體育學論文集 Vol.25 No.-
The purpose of this study was to investigate differences of and the cardiovascular function between some Trained soccer Players(TSP) and Untrained Students(US). The subiects are 15 persons respect. I acquired scientific data from Cycle Eergometer with gradual increase of, step load By this research, we draw a conclusion as follows; 1.In the Tidal Volume, It showed that there was not any remarkable differences between the 2 groups. 2.In the Ventilation, It showed that there was not any remarkable differences between the 2 groups at rest. In the maximum Ve, It showed that there was a difference(p<.01) between US 106.73± 17.16 l/min and TSP 126.74± 72.86 l/min. 3.In respiratory rate, It showed that there was not any remarkable difference between the 2 groups at rest. 4.In the Heart Rate, It showed that there was not any remarkable difference between the 2 groups at rest. In maximum Heart Rate, It showed that there was a difference(p<.01) between US 197.37±9.95 beat/min and TSP 182.33 ±7.79 beats/min. 5.In Oxygen pulse, It showed that there was not any remarkable difference between the 2 groups at rest. In maximum Oxygen pulse, It showed that there was a difference(p<.01) between US 14.89±2.56ml/beats and TSP 20.26 ± 3.72ml/beats. 6.In the Oxygen Consumption. It showed that there was not any remarkable differences between the 2 groups at rest. In maximum Oxygen Consumption, It showed that there was a difference(p<.01) between US 2925.25±407.87ml/min and TSP 3670.13±555.18ml/min. 7.In the Ventilation of Carbon dixide production, It showed that there was not any remarkable difference between the 2 groups at rest. In maximum Ventilation. of Carbon dixide production. It showed that there was a notable differences(p<.05) between US 3865.00±673.97ml/min and TSP 4431.33 ±433.53ml/min. 8.In the Oxygen Consumption Per kg body weight, It showed that there was not any remarkable differences between the 2 groups at rest. In maximum Oxygen Consumption per kg body weight, It, showed that there was a difference(p<.(11) between US 42.97±7.98ml/kg/min and TSP 51.90±6.03 ml/kg/min.
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흰쥐 앞뇌중격부의 콜린성신경세포에서 Nerve Growth Factor 및 Galanin 의 공존
고기석,장병준,조익현 건국대학교 의과학연구소 1999 건국의과학학술지 Vol.9 No.-
Mammalian forebrain septal area, which is closely concerned in learning and memory, contains a lot of cholinergic neurons. It has been well-known that these neurons have high levels of some neurosubstances including acetylcholine. It has been reported that galanin as a neuromodulator/neurotransmitter and a nerve growth factor(NGF) as a neurotrophic factor are densely localized in rat forebrain septal area. However, the precise localization, co-localization and correlation between these neurosubstances have not been clearly elucidated yet. To identify the co-localization of these substances in rat forebrain septal area, immunohistochemistry using antibodies to choline acetyltransferase(ChAT), NGF and galanin has been accomplished on serial paraffin-sections of forebrain septal area. 1. High concentrations of ChAT, NGF and galanin positive neurons were observed in the medial septal nucleus(MS) and the diagonal bands of Broca(DBB) in the basal forebrain. 2. Approximately 80.6% of cholinergic neurons were NGF positive, and 78.0% of the neurons were galanin positive, and 71.6% of the cells exhibited positive reaction for both substances, in the forebrain septal area. 3. Some of ChAT, NGF and galanin positive neurons were distributed individually in the forebrain septal area. Based on the results mentioned above, it could be concluded that NGF and galanin were co-localized in most cholinergic neurons of the forebrain septal area. It seems that there are functional reciprocal between these substances in the forebrain septal area.
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수태중인 생쥐에 있어서 림프구아형 및 자연살해세포 활성도의 변화
최임순,고기석,신주옥 THE KOREAN SOCIETY FOR BIOMEDICAL LABORATORY SCIEN 1996 Journal of biomedical laboratory sciences Vol.2 No.2
수태기간중 태아가 모체에 의해 면역학적으로 거부반응을 일으키지 않고 동종이식 상태로 유지되는 기작을 밝히는 연구의 일환으로 C3H/HeJ계의 암컷 생쥐와 DBA/2계의 수컷 생쥐를 교배하여 모체에서 발생되는 체계적인 면역기능 및 국소적 면역기능현상에 대하여 연구하고자 수태기간별로 비장 및 자궁으로 들어가는 림프절에서 T세포 및 B세포의 아형을 측정하였고 자연살해 세포의 활성도를 측정하였다. 또한 수태혈청 및 수태성 호르몬이 자연살해세포의 활성도에 미치는 영향을 알아보았다. 각 수태기간별로 비장세포에 있어서 T세포와 B세포의 아형을 관찰한 결과, Thy-1.2+ 세포는 수태기간중 중기 이후에 감소하기 시작하여 수태 4기에는 대조군에 비하여 유의하게 감소하였으며 수태말기에는 회복하였다. L3T4+ 세포도 Thy-1.2+ 세포와 비교하여 비슷한 경향으로 감소 또는 증가하였다. Ly2+ 세포는 수태중기 이후부터 대조군에 비하여 유의하게 증가하였으며, B세포는 수태중기 이후부터 수태말기까지 계속 증가하였다. 비장에 있어서 자연살해세포의 세포독성은 수태 5일에서 수태 8일사이에 가장 증가하였으며 그 이후는 대조군 수준으로 감소하였다. 정상혈청 및 수태혈청의 자연살해세포의 세포독성에 대한 영향을 수태시기별로 조사한 결과, 정상혈청과 수태혈청 모두 자연살해세포의 세포독성을 유의하게 억제하였으며, Progesterone은 시험관 내 실험과 생체내 실험 모두 약리적인 농도이상에서 농도에 의존적으로 자연살해세포의 세포독성을 증가시켰으며, HCG는 5 unit/ml에서 5000 unit/ml까지 처리농도에 비례하여 자연살해세포의 세포독성을 억제하였다. 자궁으로 들어가는 림프절에서 T세포의 아형은 Thy-1.2+ 세포는 수태 2기부터 증가하여 대조군보다 유의하게 증가하였으며, L3T4+ 세포의 유의한 변화없이 Ly2+ 세포가 수태 2기 이후부터 대조군에 비하여 유의하게 증가하였고 분만 직전에는 조금 감소하였다. 자궁으로 들어가는 림프절에서의 자연살해세포의 세포독성은 착상직후 대조군에 비하여 유의하게 증가하였으며, 수태중기와 수태후기에도 대조군에 비하여 세포독성이 증가하였으며, 같은시기의 비장세포의 자연살해세포의 세포독성보다 높게 나타났다. The conceptus which are resulted by mating between two genetically non-identical partners can be considered to be an allograft to the mother science which is not rejected by the mother's immunological attack. The present studies have been, therefore, attempted in order to elucidate the mechanism by which protection of the feto-placental allograft, between the C3H/HeJ female mouse and DBA/2 male mouse occurred. For this purpose, firstly systemic immunity was investigated by measuring T and B lymphocytes subsets. Natural killer cell activity in maternal splenic tissue and by observing the effects of pregnancy serums, progesterone and hCG on immune systems. Secondly, local immunity also investigated by measuring T lymphocytes subsets, natural killer cell activity in lymph nodes draining the uterus. The subsets of Thy-1.2+. cells and L3T4+ cells decreased slightly while the subsets of Ly2+ cell increased significantly compared with those of the control group beyond the mid-gestational stage. The subsets of B cell gradually in-creased from the mid-gestational stage untill delivery. The natural killer cell activity in the maternal splenic tissue significantly increased during the period of 5th to 8th day of gestation. The natural killer cell activity was significantly suppressed by the pregnancy serums and non-pregnant serums compared with those of serum-free group. The treatment of hCG significantly suppressed natual killer cell activity in the dose dependent manner (1 unit/ml-1000 unit/ml) while progesterone increased the natural killer cell activity at phamarcological dose only. In the lymph nodes draining the uterus, the subsets of Thy-1.2+ cells significantly increased during the period of implantation and L3T4+ cell subsets slightly increased during the mid-gestational stage. The subsets of Ly2+ cell increased significantly during the mid-gestational stage, but decreasing slightly before delivery. The natural killer cell activity was significantly elevated after the implantation period in the lymph nodes draining the uterus. The natural killer cell activity of the lymph nodes draining the uterus was higher than those of splenic tissue during the same periods of gestation. It is therefore, concluded that during the pregnancy, the phenomena which the feto -placental allograft has not been rejected and rather protected from the maternal immunological attack might be due to local immune suppression in feto-maternal interface tissues rather than systemic immune suppression. And the subsets of Thy-1.2+ cells and L3T4+ cells mainly contribute to accepting allograft in early stage of pregnancy, while the subsets of Ly2+ cell and the subsets of B cell increased significantly compared with those of the control group beyond the mid-gestational stage, so their role in systemic immunity and local immunity gradually increased from the midgestational stage untill delivery.
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박히준,채윤병,차웅석,박종배,이혜정,이향숙,인창식,고형균,김수영,최일환,김강식,문정배,배기태,유경환,육근영,정병주,손인철,임사비나 WHO COLLABORATING CENTRE FOR TRADITIONAL MEDICINE 2004 東西醫學硏究所 論文集 Vol.2004 No.-
Background : The cun measurement System, an essential and convenient method in locating acupoints, has been widely used in the practice of acupuncture. However, traditional cun measurement has been criticized for its lack of reliability. Objectives : The purposes of this study are to determine if one cun measured by the directional methods have a consistency with that of proportional methods and to investigate which factors are related with these differences, especially in forearm. Methods : The distance between the elbow crease and the wrist crease of forearm was compared to a reference value of one cun obtained by the directional method. In this method, one cun is one third of the distance between index finger and Small finger of a subject, measured at proximal interphalangeal joint. In addition, to investigate the factors influencing the differences between these two methods, we measured the height and body weight and calculated body mass index (BMI). Finally we analyzed the factors correlated with these lengths by linear regression test. Results : The results showed that one cun obtained by the directional methods were significantly different from one cun by the proportional methods in forearm. It was demonstrated that the length acquired with the directional method was more correlated with body weight and body mass index, while the length obtained by the proportional method was more correlated with the height.
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